메뉴 건너뛰기




Volumn 21, Issue 4, 2017, Pages 478-493.e7

Autoreactive T Cells and Chronic Fungal Infection Drive Esophageal Carcinogenesis

Author keywords

autoimmune disease; autoreactive T cells; EGFR; esophageal squamous cell carcinoma; fungal infection; IKKalpha; inflammation; mucosal epithelium

Indexed keywords

AMPHOTERICIN B; EPIDERMAL GROWTH FACTOR RECEPTOR; I KAPPA B KINASE ALPHA; TUMOR MARKER; EGFR PROTEIN, MOUSE;

EID: 85017333200     PISSN: 19313128     EISSN: 19346069     Source Type: Journal    
DOI: 10.1016/j.chom.2017.03.006     Document Type: Article
Times cited : (50)

References (49)
  • 2
    • 51349111243 scopus 로고    scopus 로고
    • The tumor necrosis factor family receptors RANK and CD40 cooperatively establish the thymic medullary microenvironment and self-tolerance
    • Akiyama, T., Shimo, Y., Yanai, H., Qin, J., Ohshima, D., Maruyama, Y., Asaumi, Y., Kitazawa, J., Takayanagi, H., Penninger, J.M., et al. The tumor necrosis factor family receptors RANK and CD40 cooperatively establish the thymic medullary microenvironment and self-tolerance. Immunity 29 (2008), 423–437.
    • (2008) Immunity , vol.29 , pp. 423-437
    • Akiyama, T.1    Shimo, Y.2    Yanai, H.3    Qin, J.4    Ohshima, D.5    Maruyama, Y.6    Asaumi, Y.7    Kitazawa, J.8    Takayanagi, H.9    Penninger, J.M.10
  • 4
    • 84920755451 scopus 로고    scopus 로고
    • Mining the human autoantibody repertoire: isolation of potent IL17A-neutralizing monoclonal antibodies from a patient with thymoma
    • Beerli, R.R., Bauer, M., Fritzer, A., Rosen, L.B., Buser, R.B., Hanner, M., Maudrich, M., Nebenfuehr, M., Toepfer, J.A., Mangold, S., et al. Mining the human autoantibody repertoire: isolation of potent IL17A-neutralizing monoclonal antibodies from a patient with thymoma. MAbs 6 (2014), 1608–1620.
    • (2014) MAbs , vol.6 , pp. 1608-1620
    • Beerli, R.R.1    Bauer, M.2    Fritzer, A.3    Rosen, L.B.4    Buser, R.B.5    Hanner, M.6    Maudrich, M.7    Nebenfuehr, M.8    Toepfer, J.A.9    Mangold, S.10
  • 5
    • 0035861314 scopus 로고    scopus 로고
    • IKKalpha provides an essential link between RANK signaling and cyclin D1 expression during mammary gland development
    • Cao, Y., Bonizzi, G., Seagroves, T.N., Greten, F.R., Johnson, R., Schmidt, E.V., Karin, M., IKKalpha provides an essential link between RANK signaling and cyclin D1 expression during mammary gland development. Cell 107 (2001), 763–775.
    • (2001) Cell , vol.107 , pp. 763-775
    • Cao, Y.1    Bonizzi, G.2    Seagroves, T.N.3    Greten, F.R.4    Johnson, R.5    Schmidt, E.V.6    Karin, M.7
  • 6
    • 0034793241 scopus 로고    scopus 로고
    • Rapid identification of yeasts in positive blood cultures by a multiplex PCR method
    • Chang, H.C., Leaw, S.N., Huang, A.H., Wu, T.L., Chang, T.C., Rapid identification of yeasts in positive blood cultures by a multiplex PCR method. J. Clin. Microbiol. 39 (2001), 3466–3471.
    • (2001) J. Clin. Microbiol. , vol.39 , pp. 3466-3471
    • Chang, H.C.1    Leaw, S.N.2    Huang, A.H.3    Wu, T.L.4    Chang, T.C.5
  • 7
    • 84911881867 scopus 로고    scopus 로고
    • B7-H1 expression associates with tumor invasion and predicts patient's survival in human esophageal cancer
    • Chen, L., Deng, H., Lu, M., Xu, B., Wang, Q., Jiang, J., Wu, C., B7-H1 expression associates with tumor invasion and predicts patient's survival in human esophageal cancer. Int. J. Clin. Exp. Pathol. 7 (2014), 6015–6023.
    • (2014) Int. J. Clin. Exp. Pathol. , vol.7 , pp. 6015-6023
    • Chen, L.1    Deng, H.2    Lu, M.3    Xu, B.4    Wang, Q.5    Jiang, J.6    Wu, C.7
  • 9
    • 44449150382 scopus 로고    scopus 로고
    • IL-13 attenuates gastrointestinal candidiasis in normal and immunodeficient RAG-2(-/-) mice via peroxisome proliferator-activated receptor-gamma activation
    • Coste, A., Lagane, C., Filipe, C., Authier, H., Galès, A., Bernad, J., Douin-Echinard, V., Lepert, J.C., Balard, P., Linas, M.D., et al. IL-13 attenuates gastrointestinal candidiasis in normal and immunodeficient RAG-2(-/-) mice via peroxisome proliferator-activated receptor-gamma activation. J. Immunol. 180 (2008), 4939–4947.
    • (2008) J. Immunol. , vol.180 , pp. 4939-4947
    • Coste, A.1    Lagane, C.2    Filipe, C.3    Authier, H.4    Galès, A.5    Bernad, J.6    Douin-Echinard, V.7    Lepert, J.C.8    Balard, P.9    Linas, M.D.10
  • 10
    • 40649097065 scopus 로고    scopus 로고
    • IKKalpha is a critical coregulator of a Smad4-independent TGFbeta-Smad2/3 signaling pathway that controls keratinocyte differentiation
    • Descargues, P., Sil, A.K., Sano, Y., Korchynskyi, O., Han, G., Owens, P., Wang, X.J., Karin, M., IKKalpha is a critical coregulator of a Smad4-independent TGFbeta-Smad2/3 signaling pathway that controls keratinocyte differentiation. Proc. Natl. Acad. Sci. USA 105 (2008), 2487–2492.
    • (2008) Proc. Natl. Acad. Sci. USA , vol.105 , pp. 2487-2492
    • Descargues, P.1    Sil, A.K.2    Sano, Y.3    Korchynskyi, O.4    Han, G.5    Owens, P.6    Wang, X.J.7    Karin, M.8
  • 11
    • 0034888441 scopus 로고    scopus 로고
    • Detection and identification of fungal pathogens by PCR and by ITS2 and 5.8S ribosomal DNA typing in ocular infections
    • Ferrer, C., Colom, F., Frasés, S., Mulet, E., Abad, J.L., Alió, J.L., Detection and identification of fungal pathogens by PCR and by ITS2 and 5.8S ribosomal DNA typing in ocular infections. J. Clin. Microbiol. 39 (2001), 2873–2879.
    • (2001) J. Clin. Microbiol. , vol.39 , pp. 2873-2879
    • Ferrer, C.1    Colom, F.2    Frasés, S.3    Mulet, E.4    Abad, J.L.5    Alió, J.L.6
  • 14
    • 34247868281 scopus 로고    scopus 로고
    • Medullary thymic epithelial cells expressing Aire represent a unique lineage derived from cells expressing claudin
    • Hamazaki, Y., Fujita, H., Kobayashi, T., Choi, Y., Scott, H.S., Matsumoto, M., Minato, N., Medullary thymic epithelial cells expressing Aire represent a unique lineage derived from cells expressing claudin. Nat. Immunol. 8 (2007), 304–311.
    • (2007) Nat. Immunol. , vol.8 , pp. 304-311
    • Hamazaki, Y.1    Fujita, H.2    Kobayashi, T.3    Choi, Y.4    Scott, H.S.5    Matsumoto, M.6    Minato, N.7
  • 15
    • 0033537767 scopus 로고    scopus 로고
    • Abnormal morphogenesis but intact IKK activation in mice lacking the IKKalpha subunit of IkappaB kinase
    • Hu, Y., Baud, V., Delhase, M., Zhang, P., Deerinck, T., Ellisman, M., Johnson, R., Karin, M., Abnormal morphogenesis but intact IKK activation in mice lacking the IKKalpha subunit of IkappaB kinase. Science 284 (1999), 316–320.
    • (1999) Science , vol.284 , pp. 316-320
    • Hu, Y.1    Baud, V.2    Delhase, M.3    Zhang, P.4    Deerinck, T.5    Ellisman, M.6    Johnson, R.7    Karin, M.8
  • 16
    • 0035809983 scopus 로고    scopus 로고
    • IKKalpha controls formation of the epidermis independently of NF-kappaB
    • Hu, Y., Baud, V., Oga, T., Kim, K.I., Yoshida, K., Karin, M., IKKalpha controls formation of the epidermis independently of NF-kappaB. Nature 410 (2001), 710–714.
    • (2001) Nature , vol.410 , pp. 710-714
    • Hu, Y.1    Baud, V.2    Oga, T.3    Kim, K.I.4    Yoshida, K.5    Karin, M.6
  • 17
    • 79958806173 scopus 로고    scopus 로고
    • mTOR kinase inhibitor AZD8055 enhances the immunotherapeutic activity of an agonist CD40 antibody in cancer treatment
    • Jiang, Q., Weiss, J.M., Back, T., Chan, T., Ortaldo, J.R., Guichard, S., Wiltrout, R.H., mTOR kinase inhibitor AZD8055 enhances the immunotherapeutic activity of an agonist CD40 antibody in cancer treatment. Cancer Res. 71 (2011), 4074–4084.
    • (2011) Cancer Res. , vol.71 , pp. 4074-4084
    • Jiang, Q.1    Weiss, J.M.2    Back, T.3    Chan, T.4    Ortaldo, J.R.5    Guichard, S.6    Wiltrout, R.H.7
  • 18
    • 0036088555 scopus 로고    scopus 로고
    • Distinct clinical phenotype and immunoreactivity in Japanese siblings with autoimmune polyglandular syndrome type 1 (APS-1) associated with compound heterozygous novel AIRE gene mutations
    • Kogawa, K., Kudoh, J., Nagafuchi, S., Ohga, S., Katsuta, H., Ishibashi, H., Harada, M., Hara, T., Shimizu, N., Distinct clinical phenotype and immunoreactivity in Japanese siblings with autoimmune polyglandular syndrome type 1 (APS-1) associated with compound heterozygous novel AIRE gene mutations. Clin. Immunol. 103 (2002), 277–283.
    • (2002) Clin. Immunol. , vol.103 , pp. 277-283
    • Kogawa, K.1    Kudoh, J.2    Nagafuchi, S.3    Ohga, S.4    Katsuta, H.5    Ishibashi, H.6    Harada, M.7    Hara, T.8    Shimizu, N.9
  • 19
    • 79955718316 scopus 로고    scopus 로고
    • Transcriptional regulation of the Th17 immune response by IKK(alpha)
    • Li, L., Ruan, Q., Hilliard, B., Devirgiliis, J., Karin, M., Chen, Y.H., Transcriptional regulation of the Th17 immune response by IKK(alpha). J. Exp. Med. 208 (2011), 787–796.
    • (2011) J. Exp. Med. , vol.208 , pp. 787-796
    • Li, L.1    Ruan, Q.2    Hilliard, B.3    Devirgiliis, J.4    Karin, M.5    Chen, Y.H.6
  • 20
    • 84931296945 scopus 로고    scopus 로고
    • Epidermal growth factor receptor protein overexpression and gene amplification are associated with aggressive biological behaviors of esophageal squamous cell carcinoma
    • Lin, G., Sun, X.J., Han, Q.B., Wang, Z., Xu, Y.P., Gu, J.L., Wu, W., Zhang, G.U., Hu, J.L., Sun, W.Y., Mao, W.M., Epidermal growth factor receptor protein overexpression and gene amplification are associated with aggressive biological behaviors of esophageal squamous cell carcinoma. Oncol. Lett. 10 (2015), 901–906.
    • (2015) Oncol. Lett. , vol.10 , pp. 901-906
    • Lin, G.1    Sun, X.J.2    Han, Q.B.3    Wang, Z.4    Xu, Y.P.5    Gu, J.L.6    Wu, W.7    Zhang, G.U.8    Hu, J.L.9    Sun, W.Y.10    Mao, W.M.11
  • 21
    • 33751217161 scopus 로고    scopus 로고
    • A critical role for I kappaB kinase alpha in the development of human and mouse squamous cell carcinomas
    • Liu, B., Park, E., Zhu, F., Bustos, T., Liu, J., Shen, J., Fischer, S.M., Hu, Y., A critical role for I kappaB kinase alpha in the development of human and mouse squamous cell carcinomas. Proc. Natl. Acad. Sci. USA 103 (2006), 17202–17207.
    • (2006) Proc. Natl. Acad. Sci. USA , vol.103 , pp. 17202-17207
    • Liu, B.1    Park, E.2    Zhu, F.3    Bustos, T.4    Liu, J.5    Shen, J.6    Fischer, S.M.7    Hu, Y.8
  • 23
    • 81155128592 scopus 로고    scopus 로고
    • IKKα represses a network of inflammation and proliferation pathways and elevates c-Myc antagonists and differentiation in a dose-dependent manner in the skin
    • Liu, B., Willette-Brown, J., Liu, S., Chen, X., Fischer, S.M., Hu, Y., IKKα represses a network of inflammation and proliferation pathways and elevates c-Myc antagonists and differentiation in a dose-dependent manner in the skin. Cell Death Differ. 18 (2011), 1854–1864.
    • (2011) Cell Death Differ. , vol.18 , pp. 1854-1864
    • Liu, B.1    Willette-Brown, J.2    Liu, S.3    Chen, X.4    Fischer, S.M.5    Hu, Y.6
  • 24
    • 33846237346 scopus 로고    scopus 로고
    • Thymus medulla formation and central tolerance are restored in IKKalpha-/- mice that express an IKKalpha transgene in keratin 5+ thymic epithelial cells
    • Lomada, D., Liu, B., Coghlan, L., Hu, Y., Richie, E.R., Thymus medulla formation and central tolerance are restored in IKKalpha-/- mice that express an IKKalpha transgene in keratin 5+ thymic epithelial cells. J. Immunol. 178 (2007), 829–837.
    • (2007) J. Immunol. , vol.178 , pp. 829-837
    • Lomada, D.1    Liu, B.2    Coghlan, L.3    Hu, Y.4    Richie, E.R.5
  • 25
    • 34548844747 scopus 로고    scopus 로고
    • Epigenetic inactivation of IkappaB Kinase-alpha in oral carcinomas and tumor progression
    • Maeda, G., Chiba, T., Kawashiri, S., Satoh, T., Imai, K., Epigenetic inactivation of IkappaB Kinase-alpha in oral carcinomas and tumor progression. Clin. Cancer Res. 13 (2007), 5041–5047.
    • (2007) Clin. Cancer Res. , vol.13 , pp. 5041-5047
    • Maeda, G.1    Chiba, T.2    Kawashiri, S.3    Satoh, T.4    Imai, K.5
  • 29
    • 66949140382 scopus 로고    scopus 로고
    • Clinical practice guidelines for the diagnosis and management of intravascular catheter-related infection: 2009 Update by the Infectious Diseases Society of America
    • Mermel, L.A., Allon, M., Bouza, E., Craven, D.E., Flynn, P., O'Grady, N.P., Raad, I.I., Rijnders, B.J., Sherertz, R.J., Warren, D.K., Clinical practice guidelines for the diagnosis and management of intravascular catheter-related infection: 2009 Update by the Infectious Diseases Society of America. Clin. Infect. Dis. 49 (2009), 1–45.
    • (2009) Clin. Infect. Dis. , vol.49 , pp. 1-45
    • Mermel, L.A.1    Allon, M.2    Bouza, E.3    Craven, D.E.4    Flynn, P.5    O'Grady, N.P.6    Raad, I.I.7    Rijnders, B.J.8    Sherertz, R.J.9    Warren, D.K.10
  • 30
    • 84926434301 scopus 로고    scopus 로고
    • A normal T cell receptor beta CDR3 length distribution in patients with APECED
    • Niemi, H.J., Laakso, S., Salminen, J.T., Arstila, T.P., Tuulasvaara, A., A normal T cell receptor beta CDR3 length distribution in patients with APECED. Cell. Immunol. 295 (2015), 99–104.
    • (2015) Cell. Immunol. , vol.295 , pp. 99-104
    • Niemi, H.J.1    Laakso, S.2    Salminen, J.T.3    Arstila, T.P.4    Tuulasvaara, A.5
  • 31
    • 33847291297 scopus 로고    scopus 로고
    • NADPH oxidase but not myeloperoxidase protects lymphopenic mice from spontaneous infections
    • Ostanin, D.V., Barlow, S., Shukla, D., Grisham, M.B., NADPH oxidase but not myeloperoxidase protects lymphopenic mice from spontaneous infections. Biochem. Biophys. Res. Commun. 355 (2007), 801–806.
    • (2007) Biochem. Biophys. Res. Commun. , vol.355 , pp. 801-806
    • Ostanin, D.V.1    Barlow, S.2    Shukla, D.3    Grisham, M.B.4
  • 32
    • 35148897233 scopus 로고    scopus 로고
    • Reduction in IkappaB kinase alpha expression promotes the development of skin papillomas and carcinomas
    • Park, E., Zhu, F., Liu, B., Xia, X., Shen, J., Bustos, T., Fischer, S.M., Hu, Y., Reduction in IkappaB kinase alpha expression promotes the development of skin papillomas and carcinomas. Cancer Res. 67 (2007), 9158–9168.
    • (2007) Cancer Res. , vol.67 , pp. 9158-9168
    • Park, E.1    Zhu, F.2    Liu, B.3    Xia, X.4    Shen, J.5    Bustos, T.6    Fischer, S.M.7    Hu, Y.8
  • 33
    • 0017140495 scopus 로고
    • Corneal chromomycosis: double infection by Phialophora verrucosa (Medlar) and Cladosporium cladosporioides (Frescenius)
    • Polack, F.M., Siverio, C., Bresky, R.H., Corneal chromomycosis: double infection by Phialophora verrucosa (Medlar) and Cladosporium cladosporioides (Frescenius). Ann. Ophthalmol. 8 (1976), 139–144.
    • (1976) Ann. Ophthalmol. , vol.8 , pp. 139-144
    • Polack, F.M.1    Siverio, C.2    Bresky, R.H.3
  • 36
    • 34249805682 scopus 로고    scopus 로고
    • Oral and oesophageal squamous cell carcinoma–a complication or component of autoimmune polyendocrinopathy-candidiasis-ectodermal dystrophy (APECED, APS-I)
    • Rautemaa, R., Hietanen, J., Niissalo, S., Pirinen, S., Perheentupa, J., Oral and oesophageal squamous cell carcinoma–a complication or component of autoimmune polyendocrinopathy-candidiasis-ectodermal dystrophy (APECED, APS-I). Oral Oncol. 43 (2007), 607–613.
    • (2007) Oral Oncol. , vol.43 , pp. 607-613
    • Rautemaa, R.1    Hietanen, J.2    Niissalo, S.3    Pirinen, S.4    Perheentupa, J.5
  • 38
    • 84899747138 scopus 로고    scopus 로고
    • Identification of genomic alterations in oesophageal squamous cell cancer
    • Song, Y., Li, L., Ou, Y., Gao, Z., Li, E., Li, X., Zhang, W., Wang, J., Xu, L., Zhou, Y., et al. Identification of genomic alterations in oesophageal squamous cell cancer. Nature 509 (2014), 91–95.
    • (2014) Nature , vol.509 , pp. 91-95
    • Song, Y.1    Li, L.2    Ou, Y.3    Gao, Z.4    Li, E.5    Li, X.6    Zhang, W.7    Wang, J.8    Xu, L.9    Zhou, Y.10
  • 39
    • 0035168386 scopus 로고    scopus 로고
    • Etiology and chemoprevention of esophageal squamous cell carcinoma
    • Stoner, G.D., Gupta, A., Etiology and chemoprevention of esophageal squamous cell carcinoma. Carcinogenesis 22 (2001), 1737–1746.
    • (2001) Carcinogenesis , vol.22 , pp. 1737-1746
    • Stoner, G.D.1    Gupta, A.2
  • 40
    • 84901296354 scopus 로고    scopus 로고
    • The mycobiota: interactions between commensal fungi and the host immune system
    • Underhill, D.M., Iliev, I.D., The mycobiota: interactions between commensal fungi and the host immune system. Nat. Rev. Immunol. 14 (2014), 405–416.
    • (2014) Nat. Rev. Immunol. , vol.14 , pp. 405-416
    • Underhill, D.M.1    Iliev, I.D.2
  • 42
    • 57149083878 scopus 로고    scopus 로고
    • The application of real-time PCR to the analysis of T cell repertoires
    • Wettstein, P., Strausbauch, M., Therneau, T., Borson, N., The application of real-time PCR to the analysis of T cell repertoires. Nucleic Acids Res., 36, 2008, e140.
    • (2008) Nucleic Acids Res. , vol.36 , pp. e140
    • Wettstein, P.1    Strausbauch, M.2    Therneau, T.3    Borson, N.4
  • 43
    • 77952066545 scopus 로고    scopus 로고
    • Reduction of IKKalpha expression promotes chronic ultraviolet B exposure-induced skin inflammation and carcinogenesis
    • Xia, X., Park, E., Liu, B., Willette-Brown, J., Gong, W., Wang, J., Mitchell, D., Fischer, S.M., Hu, Y., Reduction of IKKalpha expression promotes chronic ultraviolet B exposure-induced skin inflammation and carcinogenesis. Am. J. Pathol. 176 (2010), 2500–2508.
    • (2010) Am. J. Pathol. , vol.176 , pp. 2500-2508
    • Xia, X.1    Park, E.2    Liu, B.3    Willette-Brown, J.4    Gong, W.5    Wang, J.6    Mitchell, D.7    Fischer, S.M.8    Hu, Y.9
  • 47
    • 34447333358 scopus 로고    scopus 로고
    • IKKalpha shields 14-3-3sigma, a G(2)/M cell cycle checkpoint gene, from hypermethylation, preventing its silencing
    • Zhu, F., Xia, X., Liu, B., Shen, J., Hu, Y., Person, M., Hu, Y., IKKalpha shields 14-3-3sigma, a G(2)/M cell cycle checkpoint gene, from hypermethylation, preventing its silencing. Mol. Cell 27 (2007), 214–227.
    • (2007) Mol. Cell , vol.27 , pp. 214-227
    • Zhu, F.1    Xia, X.2    Liu, B.3    Shen, J.4    Hu, Y.5    Person, M.6    Hu, Y.7
  • 48
    • 84865545145 scopus 로고    scopus 로고
    • EGFR and HER2 receptor kinase signaling mediate epithelial cell invasion by Candida albicans during oropharyngeal infection
    • Zhu, W., Phan, Q.T., Boontheung, P., Solis, N.V., Loo, J.A., Filler, S.G., EGFR and HER2 receptor kinase signaling mediate epithelial cell invasion by Candida albicans during oropharyngeal infection. Proc. Natl. Acad. Sci. USA 109 (2012), 14194–14199.
    • (2012) Proc. Natl. Acad. Sci. USA , vol.109 , pp. 14194-14199
    • Zhu, W.1    Phan, Q.T.2    Boontheung, P.3    Solis, N.V.4    Loo, J.A.5    Filler, S.G.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.