메뉴 건너뛰기




Volumn 17, Issue 1, 2017, Pages

Impact of antiviral therapy on hepatocellular carcinoma and mortality in patients with chronic hepatitis C: Systematic review and meta-analysis

Author keywords

Antiviral therapy; Chronic hepatitis C; Hepatocellular carcinoma; Mortality; Sustained virologic response

Indexed keywords

ALPHA INTERFERON; BETA INTERFERON; LYMPHOBLAST INTERFERON; PEGINTERFERON; RIBAVIRIN; ANTIVIRUS AGENT;

EID: 85017035440     PISSN: None     EISSN: 1471230X     Source Type: Journal    
DOI: 10.1186/s12876-017-0606-9     Document Type: Article
Times cited : (47)

References (78)
  • 1
    • 84939653819 scopus 로고    scopus 로고
    • Hepatitis C guidance: AASLD-IDSA recommendations for testing, managing, and treating adults infected with hepatitis C virus
    • AASLD/IDSA HCV Guidance Panel. Hepatitis C guidance: AASLD-IDSA recommendations for testing, managing, and treating adults infected with hepatitis C virus. Hepatology. 2015;62:932-54.
    • (2015) Hepatology , vol.62 , pp. 932-954
  • 3
    • 77950597305 scopus 로고    scopus 로고
    • Twelve weeks posttreatment follow-up is as relevant as 24 weeks to determine the sustained virologic response in patients with hepatitis c virus receiving pegylated interferon and ribavirin
    • Martinot-Peignoux M, Stern C, Maylin S, Ripault MP, Boyer N, Leclere L, Castelnau C, Giuily N, El Ray A, Cardoso AC, et al. Twelve weeks posttreatment follow-up is as relevant as 24 weeks to determine the sustained virologic response in patients with hepatitis c virus receiving pegylated interferon and ribavirin. Hepatology. 2010;51:1122-6.
    • (2010) Hepatology , vol.51 , pp. 1122-1126
    • Martinot-Peignoux, M.1    Stern, C.2    Maylin, S.3    Ripault, M.P.4    Boyer, N.5    Leclere, L.6    Castelnau, C.7    Giuily, N.8    Ray, A.9    Cardoso, A.C.10
  • 4
    • 84980318493 scopus 로고    scopus 로고
    • A comprehensive long-term prognosis of chronic hepatitis C patients with antiviral therapy: a meta-analysis of studies from 2008 to 2014
    • Wen Y, Zheng YX, de Tan M. A comprehensive long-term prognosis of chronic hepatitis C patients with antiviral therapy: a meta-analysis of studies from 2008 to 2014. Hepat Mon. 2015;15:e27181.
    • (2015) Hepat Mon , vol.15
    • Wen, Y.1    Zheng, Y.X.2    Tan, M.3
  • 6
    • 77957661914 scopus 로고    scopus 로고
    • Critical evaluation of the Newcastle-Ottawa scale for the assessment of the quality of nonrandomized studies in meta-analyses
    • Stang A. Critical evaluation of the Newcastle-Ottawa scale for the assessment of the quality of nonrandomized studies in meta-analyses. Eur J Epidemiol. 2010;25:603-5.
    • (2010) Eur J Epidemiol , vol.25 , pp. 603-605
    • Stang, A.1
  • 8
    • 0037098199 scopus 로고    scopus 로고
    • Quantifying heterogeneity in a meta-analysis
    • Higgins JP, Thompson SG. Quantifying heterogeneity in a meta-analysis. Stat Med. 2002;21:1539-58.
    • (2002) Stat Med , vol.21 , pp. 1539-1558
    • Higgins, J.P.1    Thompson, S.G.2
  • 11
    • 0033934949 scopus 로고    scopus 로고
    • Trim and fill: a simple funnel-plot-based method of testing and adjusting for publication bias in meta-analysis
    • Duval S, Tweedie R. Trim and fill: a simple funnel-plot-based method of testing and adjusting for publication bias in meta-analysis. Biometrics. 2000;56:455-63.
    • (2000) Biometrics , vol.56 , pp. 455-463
    • Duval, S.1    Tweedie, R.2
  • 13
    • 0034823867 scopus 로고    scopus 로고
    • Funnel plots for detecting bias in meta-analysis: guidelines on choice of axis
    • Sterne JA, Egger M. Funnel plots for detecting bias in meta-analysis: guidelines on choice of axis. J Clin Epidemiol. 2001;54:1046-55.
    • (2001) J Clin Epidemiol , vol.54 , pp. 1046-1055
    • Sterne, J.A.1    Egger, M.2
  • 14
    • 0028659004 scopus 로고
    • Operating characteristics of a rank correlation test for publication bias
    • Begg CB, Mazumdar M. Operating characteristics of a rank correlation test for publication bias. Biometrics. 1994;50:1088-101.
    • (1994) Biometrics , vol.50 , pp. 1088-1101
    • Begg, C.B.1    Mazumdar, M.2
  • 15
    • 0030922816 scopus 로고    scopus 로고
    • Bias in meta-analysis detected by a simple, graphical test
    • Egger M, Davey Smith G, Schneider M, Minder C. Bias in meta-analysis detected by a simple, graphical test. BMJ. 1997;315:629-34.
    • (1997) BMJ , vol.315 , pp. 629-634
    • Egger, M.1    Davey Smith, G.2    Schneider, M.3    Minder, C.4
  • 17
    • 12144289051 scopus 로고    scopus 로고
    • Interferon treatment improves survival in chronic hepatitis C patients showing biochemical as well as virological responses by preventing liver-related death
    • Kasahara A, Tanaka H, Okanoue T, Imai Y, Tsubouchi H, Yoshioka K, Kawata S, Tanaka E, Hino K, Hayashi K, et al. Interferon treatment improves survival in chronic hepatitis C patients showing biochemical as well as virological responses by preventing liver-related death. J Viral Hepat. 2004;11:148-56.
    • (2004) J Viral Hepat , vol.11 , pp. 148-156
    • Kasahara, A.1    Tanaka, H.2    Okanoue, T.3    Imai, Y.4    Tsubouchi, H.5    Yoshioka, K.6    Kawata, S.7    Tanaka, E.8    Hino, K.9    Hayashi, K.10
  • 19
    • 33745838657 scopus 로고    scopus 로고
    • Long-term effect of interferon alpha-2b plus ribavirin therapy on incidence of hepatocellular carcinoma in patients with hepatitis C virus-related cirrhosis
    • Hung CH, Lee CM, Lu SN, Wang JH, Hu TH, Tung HD, Chen CH, Chen WJ, Changchien CS. Long-term effect of interferon alpha-2b plus ribavirin therapy on incidence of hepatocellular carcinoma in patients with hepatitis C virus-related cirrhosis. J Viral Hepat. 2006;13:409-14.
    • (2006) J Viral Hepat , vol.13 , pp. 409-414
    • Hung, C.H.1    Lee, C.M.2    Lu, S.N.3    Wang, J.H.4    Hu, T.H.5    Tung, H.D.6    Chen, C.H.7    Chen, W.J.8    Changchien, C.S.9
  • 21
    • 77954696779 scopus 로고    scopus 로고
    • Meta-analysis: reduced incidence of hepatocellular carcinoma in patients not responding to interferon therapy of chronic hepatitis C
    • Miyake Y, Iwasaki Y, Yamamoto K. Meta-analysis: reduced incidence of hepatocellular carcinoma in patients not responding to interferon therapy of chronic hepatitis C. Int J Cancer. 2010;127:989-96.
    • (2010) Int J Cancer , vol.127 , pp. 989-996
    • Miyake, Y.1    Iwasaki, Y.2    Yamamoto, K.3
  • 25
    • 0030744373 scopus 로고    scopus 로고
    • Effectiveness of interferon Alfa on incidence of hepatocellular carcinoma and decompensation in cirrhosis type C. European concerted action on viral hepatitis (EUROHEP)
    • Fattovich G, Giustina G, Degos F, Diodati G, Tremolada F, Nevens F, Almasio P, Solinas A, Brouwer JT, Thomas H, et al. Effectiveness of interferon Alfa on incidence of hepatocellular carcinoma and decompensation in cirrhosis type C. European concerted action on viral hepatitis (EUROHEP). J Hepatol. 1997;27:201-5.
    • (1997) J Hepatol , vol.27 , pp. 201-205
    • Fattovich, G.1    Giustina, G.2    Degos, F.3    Diodati, G.4    Tremolada, F.5    Nevens, F.6    Almasio, P.7    Solinas, A.8    Brouwer, J.T.9    Thomas, H.10
  • 27
    • 0032169816 scopus 로고    scopus 로고
    • Retrospective analysis of the effect of interferon therapy on the clinical outcome of patients with viral cirrhosis
    • Benvegnu L, Chemello L, Noventa F, Fattovich G, Pontisso P, Alberti A. Retrospective analysis of the effect of interferon therapy on the clinical outcome of patients with viral cirrhosis. Cancer. 1998;83:901-9.
    • (1998) Cancer , vol.83 , pp. 901-909
    • Benvegnu, L.1    Chemello, L.2    Noventa, F.3    Fattovich, G.4    Pontisso, P.5    Alberti, A.6
  • 28
    • 0032560376 scopus 로고    scopus 로고
    • Effect of interferon-alpha on progression of cirrhosis to hepatocellular carcinoma: a retrospective cohort study
    • International Interferon-alpha Hepatocellular Carcinoma Study Group. Effect of interferon-alpha on progression of cirrhosis to hepatocellular carcinoma: a retrospective cohort study. Lancet. 1998;351:1535-9.
    • (1998) Lancet , vol.351 , pp. 1535-1539
  • 29
    • 0343111507 scopus 로고    scopus 로고
    • Relation of interferon therapy and hepatocellular carcinoma in patients with chronic hepatitis C. Osaka hepatocellular carcinoma prevention study group
    • Imai Y, Kawata S, Tamura S, Yabuuchi I, Noda S, Inada M, Maeda Y, Shirai Y, Fukuzaki T, Kaji I, et al. Relation of interferon therapy and hepatocellular carcinoma in patients with chronic hepatitis C. Osaka hepatocellular carcinoma prevention study group. Ann Internal Med. 1998;129:94-9.
    • (1998) Ann Internal Med , vol.129 , pp. 94-99
    • Imai, Y.1    Kawata, S.2    Tamura, S.3    Yabuuchi, I.4    Noda, S.5    Inada, M.6    Maeda, Y.7    Shirai, Y.8    Fukuzaki, T.9    Kaji, I.10
  • 30
    • 0033520109 scopus 로고    scopus 로고
    • Interferon therapy reduces the risk for hepatocellular carcinoma: national surveillance program of cirrhotic and noncirrhotic patients with chronic hepatitis C in Japan. IHIT study group. Inhibition of hepatocarcinogenesis by interferon therapy
    • Yoshida H, Shiratori Y, Moriyama M, Arakawa Y, Ide T, Sata M, Inoue O, Yano M, Tanaka M, Fujiyama S, et al. Interferon therapy reduces the risk for hepatocellular carcinoma: national surveillance program of cirrhotic and noncirrhotic patients with chronic hepatitis C in Japan. IHIT study group. Inhibition of hepatocarcinogenesis by interferon therapy. Ann Internal Med. 1999;131:174-81.
    • (1999) Ann Internal Med , vol.131 , pp. 174-181
    • Yoshida, H.1    Shiratori, Y.2    Moriyama, M.3    Arakawa, Y.4    Ide, T.5    Sata, M.6    Inoue, O.7    Yano, M.8    Tanaka, M.9    Fujiyama, S.10
  • 31
    • 0032996855 scopus 로고    scopus 로고
    • Interferon therapy lowers the rate of progression to hepatocellular carcinoma in chronic hepatitis C but not significantly in an advanced stage: a retrospective study in 1148 patients. Viral hepatitis therapy study group
    • Okanoue T, Itoh Y, Minami M, Sakamoto S, Yasui K, Sakamoto M, Nishioji K, Murakami Y, Kashima K. Interferon therapy lowers the rate of progression to hepatocellular carcinoma in chronic hepatitis C but not significantly in an advanced stage: a retrospective study in 1148 patients. Viral hepatitis therapy study group. J Hepatol. 1999;30:653-9.
    • (1999) J Hepatol , vol.30 , pp. 653-659
    • Okanoue, T.1    Itoh, Y.2    Minami, M.3    Sakamoto, S.4    Yasui, K.5    Sakamoto, M.6    Nishioji, K.7    Murakami, Y.8    Kashima, K.9
  • 33
    • 0035042901 scopus 로고    scopus 로고
    • Long-term interferon therapy for 1 year or longer reduces the hepatocellular carcinogenesis rate in patients with liver cirrhosis caused by hepatitis C virus: a pilot study
    • Ikeda K, Saitoh S, Kobayashi M, Suzuki Y, Suzuki F, Tsubota A, Arase Y, Murashima N, Chayama K, Kumada H. Long-term interferon therapy for 1 year or longer reduces the hepatocellular carcinogenesis rate in patients with liver cirrhosis caused by hepatitis C virus: a pilot study. J Gastroenterol Hepatol. 2001;16:406-15.
    • (2001) J Gastroenterol Hepatol , vol.16 , pp. 406-415
    • Ikeda, K.1    Saitoh, S.2    Kobayashi, M.3    Suzuki, Y.4    Suzuki, F.5    Tsubota, A.6    Arase, Y.7    Murashima, N.8    Chayama, K.9    Kumada, H.10
  • 39
    • 33845669536 scopus 로고    scopus 로고
    • A sustained virological response to interferon or interferon/ribavirin reduces hepatocellular carcinoma and improves survival in chronic hepatitis C: a nationwide, multicentre study in Taiwan
    • Yu ML, Lin SM, Chuang WL, Dai CY, Wang JH, Lu SN, Sheen IS, Chang WY, Lee CM, Liaw YF. A sustained virological response to interferon or interferon/ribavirin reduces hepatocellular carcinoma and improves survival in chronic hepatitis C: a nationwide, multicentre study in Taiwan. Antivir Ther. 2006;11:985-94.
    • (2006) Antivir Ther , vol.11 , pp. 985-994
    • Yu, M.L.1    Lin, S.M.2    Chuang, W.L.3    Dai, C.Y.4    Wang, J.H.5    Lu, S.N.6    Sheen, I.S.7    Chang, W.Y.8    Lee, C.M.9    Liaw, Y.F.10
  • 41
    • 79959585302 scopus 로고    scopus 로고
    • Long-term outcome of chronic hepatitis C in a population-based cohort and impact of antiviral therapy: a propensity-adjusted analysis
    • Di Martino V, Crouzet J, Hillon P, Thévenot T, Minello A, Monnet E. Long-term outcome of chronic hepatitis C in a population-based cohort and impact of antiviral therapy: a propensity-adjusted analysis. J Viral Hepat. 2011;18:493-505.
    • (2011) J Viral Hepat , vol.18 , pp. 493-505
    • Martino, V.1    Crouzet, J.2    Hillon, P.3    Thévenot, T.4    Minello, A.5    Monnet, E.6
  • 42
    • 78651511517 scopus 로고    scopus 로고
    • Alpha-fetoprotein above normal levels as a risk factor for the development of hepatocellular carcinoma in patients infected with hepatitis C virus
    • Tateyama M, Yatsuhashi H, Taura N, Motoyoshi Y, Nagaoka S, Yanagi K, Abiru S, Yano K, Komori A, Migita K, et al. Alpha-fetoprotein above normal levels as a risk factor for the development of hepatocellular carcinoma in patients infected with hepatitis C virus. J Gastroenterol. 2011;46:92-100.
    • (2011) J Gastroenterol , vol.46 , pp. 92-100
    • Tateyama, M.1    Yatsuhashi, H.2    Taura, N.3    Motoyoshi, Y.4    Nagaoka, S.5    Yanagi, K.6    Abiru, S.7    Yano, K.8    Komori, A.9    Migita, K.10
  • 44
    • 84876698826 scopus 로고    scopus 로고
    • Nonresponse to interferon-alpha based treatment for chronic hepatitis C infection is associated with increased hazard of cirrhosis
    • Cozen ML, Ryan JC, Shen H, Lerrigo R, Yee RM, Sheen E, Wu R, Monto A. Nonresponse to interferon-alpha based treatment for chronic hepatitis C infection is associated with increased hazard of cirrhosis. PLoS One. 2013;8:e61568.
    • (2013) PLoS One , vol.8
    • Cozen, M.L.1    Ryan, J.C.2    Shen, H.3    Lerrigo, R.4    Yee, R.M.5    Sheen, E.6    Wu, R.7    Monto, A.8
  • 46
    • 84964076463 scopus 로고    scopus 로고
    • Improved survival among all interferon-alpha-treated patients in HCV-002, a veterans affairs hepatitis C cohort of 2211 patients, despite increased cirrhosis among nonresponders
    • Cozen ML, Ryan JC, Shen H, Cheung R, Kaplan DE, Pocha C, Brau N, Aytaman A, Schmidt WN, Pedrosa M, et al. Improved survival among all interferon-alpha-treated patients in HCV-002, a veterans affairs hepatitis C cohort of 2211 patients, despite increased cirrhosis among nonresponders. Dig Dis Sci. 2016;61:1744-56.
    • (2016) Dig Dis Sci , vol.61 , pp. 1744-1756
    • Cozen, M.L.1    Ryan, J.C.2    Shen, H.3    Cheung, R.4    Kaplan, D.E.5    Pocha, C.6    Brau, N.7    Aytaman, A.8    Schmidt, W.N.9    Pedrosa, M.10
  • 48
    • 0041530326 scopus 로고    scopus 로고
    • Favorable prognosis of chronic hepatitis C after interferon therapy by long-term cohort study
    • Imazeki F, Yokosuka O, Fukai K, Saisho H. Favorable prognosis of chronic hepatitis C after interferon therapy by long-term cohort study. Hepatology. 2003;38:493-502.
    • (2003) Hepatology , vol.38 , pp. 493-502
    • Imazeki, F.1    Yokosuka, O.2    Fukai, K.3    Saisho, H.4
  • 52
    • 0031975797 scopus 로고    scopus 로고
    • Long-term evaluation of interferon therapy in hepatitis C virus-associated cirrhosis: does IFN prevent development of hepatocellular carcinoma?
    • Tanaka K, Sata M, Uchimura Y, Suzuki H, Tanikawa K. Long-term evaluation of interferon therapy in hepatitis C virus-associated cirrhosis: does IFN prevent development of hepatocellular carcinoma? Oncol Rep. 1998;5:205-8.
    • (1998) Oncol Rep , vol.5 , pp. 205-208
    • Tanaka, K.1    Sata, M.2    Uchimura, Y.3    Suzuki, H.4    Tanikawa, K.5
  • 53
    • 0036590390 scopus 로고    scopus 로고
    • Transient biochemical response in interferon therapy decreases the development of hepatocellular carcinoma for 5 years and improves the long-term survival of chronic hepatitis C patients
    • Okanoue T, Itoh Y, Kirishima T, Daimon Y, Toyama T, Morita A, Nakajima T, Minami M. Transient biochemical response in interferon therapy decreases the development of hepatocellular carcinoma for 5 years and improves the long-term survival of chronic hepatitis C patients. Hepatol Res. 2002;23:62-77.
    • (2002) Hepatol Res , vol.23 , pp. 62-77
    • Okanoue, T.1    Itoh, Y.2    Kirishima, T.3    Daimon, Y.4    Toyama, T.5    Morita, A.6    Nakajima, T.7    Minami, M.8
  • 55
    • 35648970573 scopus 로고    scopus 로고
    • Effect of sustained virological response on long-term clinical outcome in 113 patients with compensated hepatitis C-related cirrhosis treated by interferon alpha and ribavirin
    • Braks RE, Ganne-Carrie N, Fontaine H, Paries J, Grando-Lemaire V, Beaugrand M, Pol S, Trinchet JC. Effect of sustained virological response on long-term clinical outcome in 113 patients with compensated hepatitis C-related cirrhosis treated by interferon alpha and ribavirin. World J Gastroenterol. 2007;13:5648-53.
    • (2007) World J Gastroenterol , vol.13 , pp. 5648-5653
    • Braks, R.E.1    Ganne-Carrie, N.2    Fontaine, H.3    Paries, J.4    Grando-Lemaire, V.5    Beaugrand, M.6    Pol, S.7    Trinchet, J.C.8
  • 57
    • 34548170062 scopus 로고    scopus 로고
    • Efficacy and anticarcinogenic activity of interferon for hepatitis C virus-related compensated cirrhosis in patients with genotype 1b low viral load or genotype 2
    • Hasegawa E, Kobayashi M, Kawamura Y, Yatsuji H, Sezaki H, Hosaka T, Akuta N, Suzuki F, Suzuki Y, Arase Y, et al. Efficacy and anticarcinogenic activity of interferon for hepatitis C virus-related compensated cirrhosis in patients with genotype 1b low viral load or genotype 2. Hepatol Res. 2007;37:793-800.
    • (2007) Hepatol Res , vol.37 , pp. 793-800
    • Hasegawa, E.1    Kobayashi, M.2    Kawamura, Y.3    Yatsuji, H.4    Sezaki, H.5    Hosaka, T.6    Akuta, N.7    Suzuki, F.8    Suzuki, Y.9    Arase, Y.10
  • 65
    • 79959706191 scopus 로고    scopus 로고
    • Eradication of hepatitis C virus reduces the risk of hepatocellular carcinoma in patients with compensated cirrhosis
    • Velosa J, Serejo F, Marinho R, Nunes J, Glória H. Eradication of hepatitis C virus reduces the risk of hepatocellular carcinoma in patients with compensated cirrhosis. Dig Dis Sci. 2011;56:1853-61.
    • (2011) Dig Dis Sci , vol.56 , pp. 1853-1861
    • Velosa, J.1    Serejo, F.2    Marinho, R.3    Nunes, J.4    Glória, H.5
  • 66
    • 79951704255 scopus 로고    scopus 로고
    • Long-term outcome after antiviral therapy of patients with hepatitis C virus infection and decompensated cirrhosis
    • Iacobellis A, Perri F, Valvano MR, Caruso N, Niro GA, Andriulli A. Long-term outcome after antiviral therapy of patients with hepatitis C virus infection and decompensated cirrhosis. Clin Gastroenterol Hepatol. 2011;9:249-53.
    • (2011) Clin Gastroenterol Hepatol , vol.9 , pp. 249-253
    • Iacobellis, A.1    Perri, F.2    Valvano, M.R.3    Caruso, N.4    Niro, G.A.5    Andriulli, A.6
  • 67
    • 79953216393 scopus 로고    scopus 로고
    • Impact of diabetes mellitus on incidence of hepatocellular carcinoma in chronic hepatitis C patients treated with interferon-based antiviral therapy
    • Hung CH, Lee CM, Wang JH, Hu TH, Chen CH, Lin CY, Lu SN. Impact of diabetes mellitus on incidence of hepatocellular carcinoma in chronic hepatitis C patients treated with interferon-based antiviral therapy. Int J Cancer. 2011;128:2344-52.
    • (2011) Int J Cancer , vol.128 , pp. 2344-2352
    • Hung, C.H.1    Lee, C.M.2    Wang, J.H.3    Hu, T.H.4    Chen, C.H.5    Lin, C.Y.6    Lu, S.N.7
  • 68
    • 79960268165 scopus 로고    scopus 로고
    • Post-challenge hyperglycemia is a significant risk factor for the development of hepatocellular carcinoma in patients with chronic hepatitis C
    • Takahashi H, Mizuta T, Eguchi Y, Kawaguchi Y, Kuwashiro T, Oeda S, Isoda H, Oza N, Iwane S, Izumi K, et al. Post-challenge hyperglycemia is a significant risk factor for the development of hepatocellular carcinoma in patients with chronic hepatitis C. J Gastroenterol. 2011;46:790-8.
    • (2011) J Gastroenterol , vol.46 , pp. 790-798
    • Takahashi, H.1    Mizuta, T.2    Eguchi, Y.3    Kawaguchi, Y.4    Kuwashiro, T.5    Oeda, S.6    Isoda, H.7    Oza, N.8    Iwane, S.9    Izumi, K.10
  • 70
    • 84863110199 scopus 로고    scopus 로고
    • Decrease in alpha-fetoprotein levels predicts reduced incidence of hepatocellular carcinoma in patients with hepatitis C virus infection receiving interferon therapy: a single center study
    • Osaki Y, Ueda Y, Marusawa H, Nakajima J, Kimura T, Kita R, Nishikawa H, Saito S, Henmi S, Sakamoto A, et al. Decrease in alpha-fetoprotein levels predicts reduced incidence of hepatocellular carcinoma in patients with hepatitis C virus infection receiving interferon therapy: a single center study. J Gastroenterol. 2012;47:444-51.
    • (2012) J Gastroenterol , vol.47 , pp. 444-451
    • Osaki, Y.1    Ueda, Y.2    Marusawa, H.3    Nakajima, J.4    Kimura, T.5    Kita, R.6    Nishikawa, H.7    Saito, S.8    Henmi, S.9    Sakamoto, A.10
  • 71
    • 84871487025 scopus 로고    scopus 로고
    • Association between sustained virological response and all-cause mortality among patients with chronic hepatitis C and advanced hepatic fibrosis
    • van der Meer AJ, Veldt BJ, Feld JJ, Wedemeyer H, Dufour JF, Lammert F, Duarte-Rojo A, Heathcote EJ, Manns MP, Kuske L, et al. Association between sustained virological response and all-cause mortality among patients with chronic hepatitis C and advanced hepatic fibrosis. JAMA. 2012;308:2584-93.
    • (2012) JAMA , vol.308 , pp. 2584-2593
    • Meer, A.J.1    Veldt, B.J.2    Feld, J.J.3    Wedemeyer, H.4    Dufour, J.F.5    Lammert, F.6    Duarte-Rojo, A.7    Heathcote, E.J.8    Manns, M.P.9    Kuske, L.10
  • 74
    • 84940676581 scopus 로고    scopus 로고
    • Efficacy of interferon-beta plus ribavirin combination treatment on the development of hepatocellular carcinoma in Japanese patients with chronic hepatitis C
    • Ikezaki H, Nomura H, Furusyo N, Ogawa E, Kajiwara E, Takahashi K, Kawano A, Maruyama T, Tanabe Y, Satoh T, et al. Efficacy of interferon-beta plus ribavirin combination treatment on the development of hepatocellular carcinoma in Japanese patients with chronic hepatitis C. Hepatol Res. 2016;46:E174-80.
    • (2016) Hepatol Res , vol.46 , pp. E174-E180
    • Ikezaki, H.1    Nomura, H.2    Furusyo, N.3    Ogawa, E.4    Kajiwara, E.5    Takahashi, K.6    Kawano, A.7    Maruyama, T.8    Tanabe, Y.9    Satoh, T.10
  • 77
    • 84885349052 scopus 로고    scopus 로고
    • Long-term benefit of hepatitis C therapy in a safety net hospital system: a cross-sectional study with median 5-year follow-up
    • Singal AG, Dharia TD, Malet PF, Alqahtani S, Zhang S, Cuthbert JA. Long-term benefit of hepatitis C therapy in a safety net hospital system: a cross-sectional study with median 5-year follow-up. BMJ Open. 2013;3:e003231.
    • (2013) BMJ Open , vol.3
    • Singal, A.G.1    Dharia, T.D.2    Malet, P.F.3    Alqahtani, S.4    Zhang, S.5    Cuthbert, J.A.6
  • 78
    • 84897463850 scopus 로고    scopus 로고
    • All-cause mortality and liver-related outcomes following successful antiviral treatment for chronic hepatitis C
    • Dieperink E, Pocha C, Thuras P, Knott A, Colton S, Ho SB. All-cause mortality and liver-related outcomes following successful antiviral treatment for chronic hepatitis C. Dig Dis Sci. 2014;59:872-80.
    • (2014) Dig Dis Sci , vol.59 , pp. 872-880
    • Dieperink, E.1    Pocha, C.2    Thuras, P.3    Knott, A.4    Colton, S.5    Ho, S.B.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.