Iron overload induces apoptosis of murine preosteoblast cells via ROS and inhibition of AKT pathway

Oral Diseases

Volumn 23, Issue 6, 2017, Pages 784-794

  Ke, J Y ^a,b   Cen, W J ^a,c   Zhou, X Z ^a   Li, Y R ^b   Kong, W D ^a   Jiang, J W ^d  

^a THE FIRST AFFILIATED HOSPITAL OF JINAN UNIVERSITY   (China)

^b Foshan Chancheng Stomatological Hospital   (China)

^c Hospital of Guangzhou Economic and Technological Development District   (China)

^d MEDICAL COLLEGE OF JINAN UNIVERSITY   (China)

Author keywords

apoptosis; iron overload; periodontal orthodontic treatment; preosteoblast; reactive oxygen species

Indexed keywords

4 [5 (4 METHYL 1 PIPERAZINYL)[2,5' BI 1H BENZIMIDAZOL] 2' YL]PHENOL; ACETYLCYSTEINE; CASPASE 3; CASPASE 7; CASPASE 9; DEFERASIROX; FERRIC AMMONIUM CITRATE; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE; PROTEIN BCL 2; PROTEIN KINASE B; REACTIVE OXYGEN METABOLITE; BENZOIC ACID DERIVATIVE; CASPASE; FERRIC ION; IRON CHELATING AGENT; QUATERNARY AMMONIUM DERIVATIVE; TRIAZOLE DERIVATIVE;

ANIMAL CELL; APOPTOSIS; ARTICLE; CELL CULTURE; CELL PROLIFERATION; CELL VIABILITY; CONTROLLED STUDY; CYTOTOXICITY; DOWN REGULATION; ENZYME ACTIVITY; FLUORESCENCE; GROWTH INHIBITION; HISTOCHEMISTRY; INTRACELLULAR SIGNALING; IRON OVERLOAD; MITOCHONDRIAL MEMBRANE POTENTIAL; MOUSE; NONHUMAN; OSTEOBLAST; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; STAINING; WESTERN BLOTTING; WST-8 ASSAY; ANIMAL; DRUG EFFECT; METABOLISM; MITOCHONDRION; PHOSPHORYLATION; PHYSIOLOGY; SIGNAL TRANSDUCTION;

ANIMALS; APOPTOSIS; BENZOATES; CASPASES; CELLS, CULTURED; DOWN-REGULATION; FERRIC COMPOUNDS; IRON CHELATING AGENTS; MICE; MITOCHONDRIA; OSTEOBLASTS; PHOSPHORYLATION; POLY(ADP-RIBOSE) POLYMERASES; PROTO-ONCOGENE PROTEINS C-AKT; QUATERNARY AMMONIUM COMPOUNDS; REACTIVE OXYGEN SPECIES; SIGNAL TRANSDUCTION; TRIAZOLES;

EID: 85016957239     PISSN: 1354523X     EISSN: 16010825     Source Type: Journal    
DOI: 10.1111/odi.12662     Document Type: Article

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