Sinomenine potentiates P815 cell degranulation via upregulation of Ca2+ mobilization through the Lyn/PLCγ/IP3R pathway

International Journal of Immunopathology and Pharmacology

Volumn 29, Issue 4, 2016, Pages 676-683

  Wang, Nan ^a   Liu, Rui ^a   Liu, Yanping ^a   Zhang, Ruirui ^a   He, Langchong ^a  

^a XI'AN JIAOTONG UNIVERSITY   (China)

Author keywords

anaphylaxis; degranulation; sinomenine

Indexed keywords

ANTIALLERGIC AGENT; ANTIINFLAMMATORY AGENT; CALCIUM; INOSITOL 1,4,5 TRISPHOSPHATE RECEPTOR; INTERLEUKIN 6; LYN PROTEIN-TYROSINE KINASE; MORPHINAN DERIVATIVE; PHOSPHOLIPASE C GAMMA; PROTEIN TYROSINE KINASE; SINOMENINE;

ANAPHYLAXIS; ANIMAL; BAGG ALBINO MOUSE; DEGRANULATION; DRUG EFFECTS; DRUG HYPERSENSITIVITY; INFLAMMATION; MALE; MAST CELL; METABOLISM; MOUSE; PHOSPHORYLATION; SIGNAL TRANSDUCTION; TUMOR CELL LINE; UPREGULATION;

ANAPHYLAXIS; ANIMALS; ANTI-ALLERGIC AGENTS; ANTI-INFLAMMATORY AGENTS; CALCIUM; CELL DEGRANULATION; CELL LINE, TUMOR; DRUG HYPERSENSITIVITY; INFLAMMATION; INOSITOL 1,4,5-TRISPHOSPHATE RECEPTORS; INTERLEUKIN-6; MALE; MAST CELLS; MICE; MICE, INBRED BALB C; MORPHINANS; PHOSPHOLIPASE C GAMMA; PHOSPHORYLATION; SIGNAL TRANSDUCTION; SRC-FAMILY KINASES; UP-REGULATION;

EID: 85016923366     PISSN: 03946320     EISSN: 20587384     Source Type: Journal    
DOI: 10.1177/0394632015621768     Document Type: Article

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