Deep immune profiling by mass cytometry links human T and NK cell differentiation and cytotoxic molecule expression patterns

Journal of Immunological Methods

Volumn 453, Issue , 2018, Pages 3-10

  Bengsch, Bertram ^a   Ohtani, Takuya ^a,b   Herati, Ramin Sedaghat ^a   Bovenschen, Niels ^c   Chang, Kyong Mi ^a,b   Wherry, E John ^a  

^a UNIVERSITY OF PENNSYLVANIA   (United States)

^b VETERANS AFFAIRS MEDICAL CENTER   (United States)

^c UNIVERSITY MEDICAL CENTER UTRECHT   (Netherlands)

Author keywords

Cytotoxic; Granzymes and perforin; Mass cytometry; NK cell; T cell; T cell differentiation

Indexed keywords

CD56 ANTIGEN; CHEMOKINE RECEPTOR CX3CR1; CYTOTOXIC FACTOR; GRANULYSIN; GRANZYME A; GRANZYME B; PERFORIN; CX3CR1 PROTEIN, HUMAN; PORE FORMING CYTOTOXIC PROTEIN;

ARTICLE; AUTOIMMUNITY; CD4+ T LYMPHOCYTE; CD8+ T LYMPHOCYTE; CONTROLLED STUDY; HUMAN; HUMAN CELL; INFECTION; LYMPHOCYTE DIFFERENTIATION; MASS CYTOMETRY; NATURAL KILLER CELL; NORMAL HUMAN; PERIPHERAL BLOOD MONONUCLEAR CELL; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEOMICS; T LYMPHOCYTE; TFH CELL; TH1 CELL; TUMOR IMMUNOLOGY; CELL CULTURE; CELL DIFFERENTIATION; CYTOTOXICITY; IMMUNOLOGICAL MEMORY; IMMUNOLOGY; ISOLATION AND PURIFICATION; MASS SPECTROMETRY; METABOLISM; PHYSIOLOGY; PROCEDURES; SINGLE CELL ANALYSIS;

CD56 ANTIGEN; CD8-POSITIVE T-LYMPHOCYTES; CELL DIFFERENTIATION; CELLS, CULTURED; CX3C CHEMOKINE RECEPTOR 1; CYTOTOXICITY, IMMUNOLOGIC; HEALTHY VOLUNTEERS; HUMANS; IMMUNOLOGIC MEMORY; KILLER CELLS, NATURAL; MASS SPECTROMETRY; PORE FORMING CYTOTOXIC PROTEINS; PROTEOMICS; SINGLE-CELL ANALYSIS; TH1 CELLS;

EID: 85016765617     PISSN: 00221759     EISSN: 18727905     Source Type: Journal    
DOI: 10.1016/j.jim.2017.03.009     Document Type: Article

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