Reciprocal insulation analysis of Hi-C data shows that TADs represent a functionally but not structurally privileged scale in the hierarchical folding of chromosomes

Genome Research

Volumn 27, Issue 3, 2017, Pages 479-490

  Zhan, Yinxiu ^a,b   Mariani, Luca ^c,i   Barozzi, Iros ^d   Schulz, Edda G ^c,j   Blüthgen, Nils ^e,f   Stadler, Michael ^a,g   Tiana, Guido ^h   Giorgetti, Luca ^a  

^a FRIEDRICH MIESCHER INSTITUTE FOR BIOMEDICAL RESEARCH   (Switzerland)

^b UNIVERSITY OF BASEL   (Switzerland)

^c INSTITUT CURIE   (France)

^d LAWRENCE BERKELEY NATIONAL LABORATORY   (United States)

^e CHARITÉ UNIVERSITÄTSMEDIZIN BERLIN   (Germany)

^f HUMBOLDT UNIVERSITY   (Germany)

^g SWISS INSTITUTE OF BIOINFORMATICS   (Switzerland)

^h UNIVERSITY OF MILAN   (Italy)

ⁱ BRIGHAM AND WOMEN S HOSPITAL   (United States)

^j MAX PLANCK INSTITUTE FOR MOLECULAR GENETICS   (Germany)

more..

Author keywords

[No Author keywords available]

Indexed keywords

TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR CTCF; TRANSCRIPTION FACTOR TAD; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; CATCH ALGORITHM; CELL DIFFERENTIATION; CELLS BY BODY ANATOMY; CHROMOSOMAL MAPPING; CHROMOSOME; CHROMOSOME ANALYSIS; CHROMOSOME STRUCTURE; CONTROLLED STUDY; EMBRYO; EMBRYONIC STEM CELL; FETUS; GENE SEQUENCE; GENETIC ALGORITHM; GENETIC CONSERVATION; GENOME; GENOMICS; HI C MAPPING; IN VITRO STUDY; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; PHYLOGENETIC TREE; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN FOLDING; PROTEIN LOCALIZATION; RECIPROCAL INSULATION ANALYSIS; ALGORITHM; ANIMAL; CELL CULTURE; CHEMISTRY; CHROMATIN ASSEMBLY AND DISASSEMBLY; FEMALE; GENE EXPRESSION REGULATION; GENETICS; INSULATOR ELEMENT; METABOLISM; NEURAL STEM CELL; THEORETICAL MODEL;

ALGORITHMS; ANIMALS; CELLS, CULTURED; CHROMATIN ASSEMBLY AND DISASSEMBLY; CHROMOSOMES; EMBRYONIC STEM CELLS; FEMALE; GENE EXPRESSION REGULATION, DEVELOPMENTAL; INSULATOR ELEMENTS; MICE; MODELS, THEORETICAL; NEURAL STEM CELLS;

EID: 85016499498     PISSN: 10889051     EISSN: 15495469     Source Type: Journal    
DOI: 10.1101/gr.212803.116     Document Type: Article

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