메뉴 건너뛰기




Volumn 28, Issue 6, 2017, Pages 497-528

Does milk intake promote prostate cancer initiation or progression via effects on insulin-like growth factors (IGFs)? A systematic review and meta-analysis

Author keywords

Insulin like growth factors; Mechanistic pathway; Meta analysis; Milk; Prostate cancer; Systematic review

Indexed keywords

SOMATOMEDIN; SOMATOMEDIN B; SOMATOMEDIN BINDING PROTEIN 1; SOMATOMEDIN BINDING PROTEIN 3; SOMATOMEDIN C; SOMATOMEDIN BINDING PROTEIN 2;

EID: 85016470744     PISSN: 09575243     EISSN: 15737225     Source Type: Journal    
DOI: 10.1007/s10552-017-0883-1     Document Type: Review
Times cited : (68)

References (199)
  • 2
    • 84857338212 scopus 로고    scopus 로고
    • Milk stimulates growth of prostate cancer cells in culture
    • PID: 22043817
    • Tate PL, Bibb R, Larcom LL (2011) Milk stimulates growth of prostate cancer cells in culture. Nutr Cancer 63(8):1361–1366
    • (2011) Nutr Cancer , vol.63 , Issue.8 , pp. 1361-1366
    • Tate, P.L.1    Bibb, R.2    Larcom, L.L.3
  • 3
    • 79955755462 scopus 로고    scopus 로고
    • Associations of circulating and dietary vitamin D with prostate cancer risk: a systematic review and dose-response meta-analysis
    • PID: 21203822
    • Gilbert R, Martin RM, Beynon R et al (2011) Associations of circulating and dietary vitamin D with prostate cancer risk: a systematic review and dose-response meta-analysis. Cancer Causes Control 22(3):319–340
    • (2011) Cancer Causes Control , vol.22 , Issue.3 , pp. 319-340
    • Gilbert, R.1    Martin, R.M.2    Beynon, R.3
  • 4
    • 0032576482 scopus 로고    scopus 로고
    • Xenoendocrine disrupters - environmental impacts
    • Sumpter JP (1998) Xenoendocrine disrupters - environmental impacts. Toxicol Lett 103:337–342
    • (1998) Toxicol Lett , vol.103 , pp. 337-342
    • Sumpter, J.P.1
  • 5
    • 1042265595 scopus 로고    scopus 로고
    • Estrogen: one of the risk factors in milk for prostate cancer
    • COI: 1:CAS:528:DC%2BD2cXjtVCktw%3D%3D, PID: 14729019
    • Qin LQ, Wang PY, Kaneko T et al (2004) Estrogen: one of the risk factors in milk for prostate cancer. Med Hypotheses 62(1):133–142
    • (2004) Med Hypotheses , vol.62 , Issue.1 , pp. 133-142
    • Qin, L.Q.1    Wang, P.Y.2    Kaneko, T.3
  • 6
    • 77951453523 scopus 로고    scopus 로고
    • Milk consumption and circulating insulin-like growth factor-I level: a systematic literature review
    • COI: 1:CAS:528:DC%2BD1MXhtFCgtL3E, PID: 19746296
    • Qin LQ, He K, Xu JY (2009) Milk consumption and circulating insulin-like growth factor-I level: a systematic literature review. Int J Food Sci Nutr 60:330–340
    • (2009) Int J Food Sci Nutr , vol.60 , pp. 330-340
    • Qin, L.Q.1    He, K.2    Xu, J.Y.3
  • 7
    • 64249111139 scopus 로고    scopus 로고
    • Circulating insulin-like growth factor peptides and prostate cancer risk: a systematic review and meta-analysis
    • COI: 1:CAS:528:DC%2BD1MXltFaqt7w%3D, PID: 19142965
    • Rowlands MA, Gunnell D, Harris R et al (2009) Circulating insulin-like growth factor peptides and prostate cancer risk: a systematic review and meta-analysis. Int J Cancer 124(10):2416–2429
    • (2009) Int J Cancer , vol.124 , Issue.10 , pp. 2416-2429
    • Rowlands, M.A.1    Gunnell, D.2    Harris, R.3
  • 8
    • 84862908410 scopus 로고    scopus 로고
    • Circulating insulin-like growth factors and IGF-binding proteins in PSA-detected prostate cancer: The Large Case-Control Study ProtecT
    • COI: 1:CAS:528:DC%2BC38Xos1Kktw%3D%3D, PID: 22106399
    • Rowlands MA, Holly JMP, Gunnell D et al (2012) Circulating insulin-like growth factors and IGF-binding proteins in PSA-detected prostate cancer: The Large Case-Control Study ProtecT. Cancer Res 72(2):503–515
    • (2012) Cancer Res , vol.72 , Issue.2 , pp. 503-515
    • Rowlands, M.A.1    Holly, J.M.P.2    Gunnell, D.3
  • 9
    • 53749097826 scopus 로고    scopus 로고
    • Insulin-like growth factors, their binding proteins, and prostate cancer risk: analysis of individual patient data from 12 prospective studies
    • PID: 18838726
    • Roddam AW, Allen NE, Appleby P et al (2008) Insulin-like growth factors, their binding proteins, and prostate cancer risk: analysis of individual patient data from 12 prospective studies. Ann Intern Med 149(7):461–488
    • (2008) Ann Intern Med , vol.149 , Issue.7 , pp. 461-488
    • Roddam, A.W.1    Allen, N.E.2    Appleby, P.3
  • 10
    • 79952284127 scopus 로고    scopus 로고
    • Hallmarks of cancer: the next generation
    • COI: 1:CAS:528:DC%2BC3MXjsFeqtrk%3D, PID: 21376230
    • Hanahan D, Weinberg RA (2011) Hallmarks of cancer: the next generation. Cell 144(5):646–674
    • (2011) Cell , vol.144 , Issue.5 , pp. 646-674
    • Hanahan, D.1    Weinberg, R.A.2
  • 11
    • 85015912033 scopus 로고    scopus 로고
    • The Albatross plot: a novel graphical tool for presenting results of diversely reported studies in a systematic review
    • Harrison S, Jones H, Martin RM et al (2017) The Albatross plot: a novel graphical tool for presenting results of diversely reported studies in a systematic review. Res Synth Methods (in press)
    • (2017) Res Synth Methods (in press)
    • Harrison, S.1    Jones, H.2    Martin, R.M.3
  • 12
    • 85017897062 scopus 로고
    • The American soldier, vol.1, Adjustment during army life
    • Stouffer SA, Suchman EA, DeVinney LC et al (1949) The American soldier, vol. 1, Adjustment during army life. J Consult Psychol 13(4):310–310
    • (1949) J Consult Psychol , vol.13 , Issue.4 , pp. 310
    • Stouffer, S.A.1    Suchman, E.A.2    DeVinney, L.C.3
  • 13
    • 0029788142 scopus 로고    scopus 로고
    • Methods for summarizing the risk associations of quantitative variables in epidemiologic studies in a consistent form
    • COI: 1:STN:280:DyaK28zptVGgtw%3D%3D, PID: 8797521
    • Chene G, Thompson SG (1996) Methods for summarizing the risk associations of quantitative variables in epidemiologic studies in a consistent form. Am J Epidemiol 144(6):610–621
    • (1996) Am J Epidemiol , vol.144 , Issue.6 , pp. 610-621
    • Chene, G.1    Thompson, S.G.2
  • 14
    • 0026777701 scopus 로고
    • Methods for trend estimation from summarized dose-response data, with applications to metaanalysis
    • COI: 1:STN:280:DyaK38zivVShtA%3D%3D, PID: 1626547
    • Greenland S, Longnecker MP (1992) Methods for trend estimation from summarized dose-response data, with applications to metaanalysis. Am J Epidemiol 135(11):1301–1309
    • (1992) Am J Epidemiol , vol.135 , Issue.11 , pp. 1301-1309
    • Greenland, S.1    Longnecker, M.P.2
  • 15
    • 33646496189 scopus 로고    scopus 로고
    • Generalized least squares for trend estimation of summarized dose-response data
    • Orsini N, Bellocco R, Greenland S (2006) Generalized least squares for trend estimation of summarized dose-response data. Stata J 6(1):40–57
    • (2006) Stata J , vol.6 , Issue.1 , pp. 40-57
    • Orsini, N.1    Bellocco, R.2    Greenland, S.3
  • 16
    • 43749097000 scopus 로고    scopus 로고
    • Metan: fixed- and random-effects meta-analysis
    • Harris RJ, Bradburn MJ, Deeks JJ et al (2008) Metan: fixed- and random-effects meta-analysis. Stata J 8(1):3–28
    • (2008) Stata J , vol.8 , Issue.1 , pp. 3-28
    • Harris, R.J.1    Bradburn, M.J.2    Deeks, J.J.3
  • 17
    • 0037098199 scopus 로고    scopus 로고
    • Quantifying heterogeneity in a meta-analysis
    • PID: 12111919
    • Higgins JPT, Thompson SG (2002) Quantifying heterogeneity in a meta-analysis. Stat Med 21(11):1539–1558
    • (2002) Stat Med , vol.21 , Issue.11 , pp. 1539-1558
    • Higgins, J.P.T.1    Thompson, S.G.2
  • 18
    • 0030922816 scopus 로고    scopus 로고
    • Bias in meta-analysis detected by a simple, graphical test
    • COI: 1:STN:280:DyaK2svls1KjtA%3D%3D
    • Egger M, Smith GD, Schneider M et al (1997) Bias in meta-analysis detected by a simple, graphical test. Br Med J 315(7109):629–634
    • (1997) Br Med J , vol.315 , Issue.7109 , pp. 629-634
    • Egger, M.1    Smith, G.D.2    Schneider, M.3
  • 19
    • 0028659004 scopus 로고
    • Operating characteristics of a rank correlation test for publication bias
    • COI: 1:STN:280:DyaK2Mzgs1GrtQ%3D%3D, PID: 7786990
    • Begg CB, Mazumdar M (1994) Operating characteristics of a rank correlation test for publication bias. Biometrics 50(4):1088–1101
    • (1994) Biometrics , vol.50 , Issue.4 , pp. 1088-1101
    • Begg, C.B.1    Mazumdar, M.2
  • 20
    • 0037464808 scopus 로고    scopus 로고
    • Statistics Notes - Interaction revisited: the difference between two estimates
    • Altman DG, Bland JM (2003) Statistics Notes - Interaction revisited: the difference between two estimates. Br Med J 326(7382):219–219
    • (2003) Br Med J , vol.326 , Issue.7382 , pp. 219
    • Altman, D.G.1    Bland, J.M.2
  • 21
    • 84991710934 scopus 로고    scopus 로고
    • ROBINS-I: a tool for assessing risk of bias in non-randomised studies of interventions
    • Sterne JAC, Hernan MA, Reeves BC et al (2016) ROBINS-I: a tool for assessing risk of bias in non-randomised studies of interventions. BMJ-Br Med J 355:i4919
    • (2016) BMJ-Br Med J , vol.355 , pp. i4919
    • Sterne, J.A.C.1    Hernan, M.A.2    Reeves, B.C.3
  • 22
    • 85017892495 scopus 로고    scopus 로고
    • CASP Case Control Checklist [http://media.wix.com/ugd/dded87_63fb65dd4e0548e2bfd0a982295f839e.pdf]
    • CASP Case Control Checklist
  • 23
    • 85032151406 scopus 로고    scopus 로고
    • CASP Cohort Study Checklist [http://media.wix.com/ugd/dded87_e37a4ab637fe46a0869f9f977dacf134.pdf]
    • CASP Cohort Study Checklist
  • 24
    • 43049113533 scopus 로고    scopus 로고
    • GRADE: an emerging consensus on rating quality of evidence and strength of recommendations
    • Guyatt GH, Oxman AD, Vist GE et al (2008) GRADE: an emerging consensus on rating quality of evidence and strength of recommendations. Br Med J 336(7650):924–926
    • (2008) Br Med J , vol.336 , Issue.7650 , pp. 924-926
    • Guyatt, G.H.1    Oxman, A.D.2    Vist, G.E.3
  • 26
    • 79958210009 scopus 로고    scopus 로고
    • Relationship of insulin-like growth factor (IGF) binding protein-3 (IGFBP-3) gene polymorphism with the susceptibility to development of prostate cancer and influence on serum levels of IGF-I, and IGFBP-3
    • COI: 1:CAS:528:DC%2BC3MXntlGnu7s%3D, PID: 21536469
    • Safarinejad MR, Shafiei N, Safarinejad S (2011) Relationship of insulin-like growth factor (IGF) binding protein-3 (IGFBP-3) gene polymorphism with the susceptibility to development of prostate cancer and influence on serum levels of IGF-I, and IGFBP-3. Growth Horm IGF Res 21(3):146–154
    • (2011) Growth Horm IGF Res , vol.21 , Issue.3 , pp. 146-154
    • Safarinejad, M.R.1    Shafiei, N.2    Safarinejad, S.3
  • 27
    • 35748969106 scopus 로고    scopus 로고
    • Childhood diet and insulin-like growth factors in adulthood: 65-year follow-up of the Boyd Orr Cohort
    • COI: 1:STN:280:DC%2BD2snkslGgug%3D%3D, PID: 17299497
    • Martin RM, Holly JMP, Middleton N et al (2007) Childhood diet and insulin-like growth factors in adulthood: 65-year follow-up of the Boyd Orr Cohort. Eur J Clin Nutr 61(11):1281–1292
    • (2007) Eur J Clin Nutr , vol.61 , Issue.11 , pp. 1281-1292
    • Martin, R.M.1    Holly, J.M.P.2    Middleton, N.3
  • 28
    • 18544379185 scopus 로고    scopus 로고
    • Prenatal and postnatal milk supplementation and adult insulin-like growth factor I: long-term follow-up of a randomized controlled trial
    • COI: 1:CAS:528:DC%2BD2MXktFCkur0%3D
    • Ben-Shlomo Y, Holly J, McCarthy A et al (2005) Prenatal and postnatal milk supplementation and adult insulin-like growth factor I: long-term follow-up of a randomized controlled trial. Cancer Epidemiol Biomark Prev 14(5):1336–1339
    • (2005) Cancer Epidemiol Biomark Prev , vol.14 , Issue.5 , pp. 1336-1339
    • Ben-Shlomo, Y.1    Holly, J.2    McCarthy, A.3
  • 29
    • 30344464959 scopus 로고    scopus 로고
    • IGF-1, IGFBP-3, and nutritional factors in young black and white men: the CARDIA Male Hormone Study
    • COI: 1:CAS:528:DC%2BD28XptF2ktQ%3D%3D, PID: 16351507
    • Colangelo LA, Chin BCH, Liu K et al (2005) IGF-1, IGFBP-3, and nutritional factors in young black and white men: the CARDIA Male Hormone Study. Nutr Cancer 53(1):57–64
    • (2005) Nutr Cancer , vol.53 , Issue.1 , pp. 57-64
    • Colangelo, L.A.1    Chin, B.C.H.2    Liu, K.3
  • 30
    • 36749066755 scopus 로고    scopus 로고
    • Milk consumption and the prepubertal somatotropic axis
    • PID: 17900364
    • Rich-Edwards JW, Ganmaa D, Pollak MN et al (2007) Milk consumption and the prepubertal somatotropic axis. Nutr J 6:28
    • (2007) Nutr J , vol.6 , pp. 28
    • Rich-Edwards, J.W.1    Ganmaa, D.2    Pollak, M.N.3
  • 31
    • 33847783258 scopus 로고    scopus 로고
    • Impact of nutrients on insulin-like growth factor-I, insulin-like growth factor binding protein-3 and their ratio in African American and white males
    • PID: 17212848
    • McGreevy KM, D Hoel B, Lipsitz SR et al (2007) Impact of nutrients on insulin-like growth factor-I, insulin-like growth factor binding protein-3 and their ratio in African American and white males. Public Health Nutr 10(1):97–105
    • (2007) Public Health Nutr , vol.10 , Issue.1 , pp. 97-105
    • McGreevy, K.M.1    D Hoel, B.2    Lipsitz, S.R.3
  • 32
    • 62149130092 scopus 로고    scopus 로고
    • Milk, rather than other foods, is associated with vertebral bone mass and circulating IGF-1 in female adolescents
    • COI: 1:CAS:528:DC%2BD1MXis1Glurk%3D, PID: 18704544
    • Esterle L, Sabatier JP, Guillon-Metz F et al (2009) Milk, rather than other foods, is associated with vertebral bone mass and circulating IGF-1 in female adolescents. Osteoporos Int 20(4):567–575
    • (2009) Osteoporos Int , vol.20 , Issue.4 , pp. 567-575
    • Esterle, L.1    Sabatier, J.P.2    Guillon-Metz, F.3
  • 33
    • 85017907231 scopus 로고    scopus 로고
    • Protein sources in infancy as predictors for body mass index and IGF-1 concentration at the age of 6 years
    • Thorisdottir B, Gunnarsdottir I, Palsson GI et al (2013) Protein sources in infancy as predictors for body mass index and IGF-1 concentration at the age of 6 years. Ann Nutr Metab 63:793–793
    • (2013) Ann Nutr Metab , vol.63 , pp. 793
    • Thorisdottir, B.1    Gunnarsdottir, I.2    Palsson, G.I.3
  • 34
    • 84877811716 scopus 로고    scopus 로고
    • Insulin-like growth factor pathway genes and blood concentrations, dietary protein and risk of prostate cancer in the NCI Breast and Prostate Cancer Cohort Consortium (BPC3)
    • COI: 1:CAS:528:DC%2BC3sXis1Wqu7o%3D, PID: 23341348
    • Tsilidis KK, Travis RC, Appleby PN et al (2013) Insulin-like growth factor pathway genes and blood concentrations, dietary protein and risk of prostate cancer in the NCI Breast and Prostate Cancer Cohort Consortium (BPC3). Int J Cancer 133(2):495–504
    • (2013) Int J Cancer , vol.133 , Issue.2 , pp. 495-504
    • Tsilidis, K.K.1    Travis, R.C.2    Appleby, P.N.3
  • 35
    • 0035723770 scopus 로고    scopus 로고
    • Are dietary influences on the risk of prostate cancer mediated through the insulin-like growth factor system?
    • COI: 1:STN:280:DC%2BD3MzkvFajuw%3D%3D, PID: 11412218
    • Mucci LA, Tamimi R, Lagiou P et al (2001) Are dietary influences on the risk of prostate cancer mediated through the insulin-like growth factor system? Bju Int 87(9):814–820
    • (2001) Bju Int , vol.87 , Issue.9 , pp. 814-820
    • Mucci, L.A.1    Tamimi, R.2    Lagiou, P.3
  • 36
    • 0035812311 scopus 로고    scopus 로고
    • Milk intake, circulating levels of insulin-like growth factor-I, and risk of colorectal cancer in men
    • COI: 1:CAS:528:DC%2BD3MXntVKjur8%3D, PID: 11535708
    • Ma J, Giovannucci E, Pollak M et al (2001) Milk intake, circulating levels of insulin-like growth factor-I, and risk of colorectal cancer in men. J Natl Cancer Inst 93(17):1330–1336
    • (2001) J Natl Cancer Inst , vol.93 , Issue.17 , pp. 1330-1336
    • Ma, J.1    Giovannucci, E.2    Pollak, M.3
  • 37
    • 0036716967 scopus 로고    scopus 로고
    • Dietary correlates of plasma insulin-like growth factor I and insulin-like growth factor binding protein 3 concentrations
    • COI: 1:CAS:528:DC%2BD38XnvVSksbc%3D
    • Holmes MD, Pollak MN, Willett WC et al (2002) Dietary correlates of plasma insulin-like growth factor I and insulin-like growth factor binding protein 3 concentrations. Cancer Epidemiol Biomark Prev 11(9):852–861
    • (2002) Cancer Epidemiol Biomark Prev , vol.11 , Issue.9 , pp. 852-861
    • Holmes, M.D.1    Pollak, M.N.2    Willett, W.C.3
  • 38
    • 12244280783 scopus 로고    scopus 로고
    • Nutritional predictors of insulin-like growth factor I and their relationships to cancer in men
    • COI: 1:CAS:528:DC%2BD3sXhtVOks74%3D
    • Giovannucci E, Pollak M, Liu Y et al (2003) Nutritional predictors of insulin-like growth factor I and their relationships to cancer in men. Cancer Epidemiol Biomark Prev 12(2):84–89
    • (2003) Cancer Epidemiol Biomark Prev , vol.12 , Issue.2 , pp. 84-89
    • Giovannucci, E.1    Pollak, M.2    Liu, Y.3
  • 39
    • 0037929412 scopus 로고    scopus 로고
    • Are diet-prostate cancer associations mediated by the IGF axis? A cross-sectional analysis of diet, IGF-I and IGFBP-3 in healthy middle-aged men
    • COI: 1:CAS:528:DC%2BD3sXktVentLs%3D, PID: 12771980
    • Gunnell D, Oliver SE, Peters TJ et al (2003) Are diet-prostate cancer associations mediated by the IGF axis? A cross-sectional analysis of diet, IGF-I and IGFBP-3 in healthy middle-aged men. Br J Cancer 88(11):1682–1686
    • (2003) Br J Cancer , vol.88 , Issue.11 , pp. 1682-1686
    • Gunnell, D.1    Oliver, S.E.2    Peters, T.J.3
  • 40
    • 4444359550 scopus 로고    scopus 로고
    • Dietary and lifestyle correlates of plasma insulin-like growth factor-I (IGF-I) and IGF binding protein-3 (IGFBP-3): the multiethnic cohort
    • COI: 1:CAS:528:DC%2BD2cXntFCks7c%3D
    • DeLellis K, Rinaldi S, Kaaks RJ et al (2004) Dietary and lifestyle correlates of plasma insulin-like growth factor-I (IGF-I) and IGF binding protein-3 (IGFBP-3): the multiethnic cohort. Cancer Epidemiol Biomark Prev 13(9):1444–1451
    • (2004) Cancer Epidemiol Biomark Prev , vol.13 , Issue.9 , pp. 1444-1451
    • DeLellis, K.1    Rinaldi, S.2    Kaaks, R.J.3
  • 41
    • 4344685478 scopus 로고    scopus 로고
    • Animal protein intake, serum insulin-like growth factor I, and growth in healthy 2.5-year-old Danish children
    • COI: 1:CAS:528:DC%2BD2cXmtFKis7g%3D, PID: 15277169
    • Hoppe C, Udam TR, Lauritzen L et al (2004) Animal protein intake, serum insulin-like growth factor I, and growth in healthy 2.5-year-old Danish children. Am J Clin Nutr 80(2):447–452
    • (2004) Am J Clin Nutr , vol.80 , Issue.2 , pp. 447-452
    • Hoppe, C.1    Udam, T.R.2    Lauritzen, L.3
  • 42
    • 23944468840 scopus 로고    scopus 로고
    • Variation in plasma insulin-like growth factor-1 and insulin-like growth factor binding protein-3: Personal and lifestyle factors (United states)
    • PID: 16132801
    • Morimoto LM, Newcomb PA, White E et al (2005) Variation in plasma insulin-like growth factor-1 and insulin-like growth factor binding protein-3: Personal and lifestyle factors (United states). Cancer Causes Control 16(8):917–927
    • (2005) Cancer Causes Control , vol.16 , Issue.8 , pp. 917-927
    • Morimoto, L.M.1    Newcomb, P.A.2    White, E.3
  • 43
    • 33744926440 scopus 로고    scopus 로고
    • Milk as a food for growth? The insulin-like growth factors link
    • PID: 16684388
    • Rogers I, Emmett P, Gunnell D et al (2006) Milk as a food for growth? The insulin-like growth factors link. Public Health Nutr 9(3):359–368
    • (2006) Public Health Nutr , vol.9 , Issue.3 , pp. 359-368
    • Rogers, I.1    Emmett, P.2    Gunnell, D.3
  • 44
    • 33845519394 scopus 로고    scopus 로고
    • Diet, serum insulin-like growth factor-I and IGF-binding protein-3 in European women
    • COI: 1:CAS:528:DC%2BD28Xht12ktbbM, PID: 16900085
    • Norat T, Dossus L, Rinaldi S et al (2007) Diet, serum insulin-like growth factor-I and IGF-binding protein-3 in European women. Eur J Clin Nutr 61(1):91–98
    • (2007) Eur J Clin Nutr , vol.61 , Issue.1 , pp. 91-98
    • Norat, T.1    Dossus, L.2    Rinaldi, S.3
  • 45
    • 34247164537 scopus 로고    scopus 로고
    • Associations of total, dairy, and meat protein with markers for bone turnover in healthy, prepubertal boys
    • COI: 1:CAS:528:DC%2BD2sXktVSltb4%3D, PID: 17374656
    • Budek AZ, Hoppe C, Michaelsen KE et al (2007) Associations of total, dairy, and meat protein with markers for bone turnover in healthy, prepubertal boys. J Nutr 137(4):930–934
    • (2007) J Nutr , vol.137 , Issue.4 , pp. 930-934
    • Budek, A.Z.1    Hoppe, C.2    Michaelsen, K.E.3
  • 46
    • 66549097704 scopus 로고    scopus 로고
    • The Association between diet and serum concentrations of IGF-I, IGFBP-1, IGFBP-2, and IGFBP-3 in the European prospective investigation into cancer and nutrition
    • COI: 1:CAS:528:DC%2BD1MXlsFCltrw%3D
    • Crowe FL, Key TJ, Allen NE et al (2009) The Association between diet and serum concentrations of IGF-I, IGFBP-1, IGFBP-2, and IGFBP-3 in the European prospective investigation into cancer and nutrition. Cancer Epidemiol Biomark Prev 18(5):1333–1340
    • (2009) Cancer Epidemiol Biomark Prev , vol.18 , Issue.5 , pp. 1333-1340
    • Crowe, F.L.1    Key, T.J.2    Allen, N.E.3
  • 47
    • 85017888095 scopus 로고    scopus 로고
    • Associations of food and nutrient intakes with serum IGF-I, IGF-II, IGFBP-3, TGF-beta 1, Total SOD activity and sFas levels among middle-aged Japanese: the JACC Study
    • Maruyama K, Iso H, Ito Y et al (2009) Associations of food and nutrient intakes with serum IGF-I, IGF-II, IGFBP-3, TGF-beta 1, Total SOD activity and sFas levels among middle-aged Japanese: the JACC Study. Asian Pac J Cancer Prev 10:6–22
    • (2009) Asian Pac J Cancer Prev , vol.10 , pp. 6-22
    • Maruyama, K.1    Iso, H.2    Ito, Y.3
  • 48
    • 84862486305 scopus 로고    scopus 로고
    • A cross-sectional analysis of the association between diet and insulin-like growth factor (IGF)-I, IGF-II, IGF-binding protein (IGFBP)-2, and IGFBP-3 in men in the United Kingdom
    • PID: 22527168
    • Young NJ, Metcalfe C, Gunnell D et al (2012) A cross-sectional analysis of the association between diet and insulin-like growth factor (IGF)-I, IGF-II, IGF-binding protein (IGFBP)-2, and IGFBP-3 in men in the United Kingdom. Cancer Causes Control 23(6):907–917
    • (2012) Cancer Causes Control , vol.23 , Issue.6 , pp. 907-917
    • Young, N.J.1    Metcalfe, C.2    Gunnell, D.3
  • 49
    • 34548260369 scopus 로고    scopus 로고
    • Lifestyle and dietary correlates of plasma insulin-like growth factor binding protein-1 (IGFBP-1), leptin, and C-peptide: the multiethnic cohort
    • COI: 1:CAS:528:DC%2BD2sXhtVOgt7bJ, PID: 17640159
    • Delellis Henderson K, Rinaldi S, Kaaks R et al (2007) Lifestyle and dietary correlates of plasma insulin-like growth factor binding protein-1 (IGFBP-1), leptin, and C-peptide: the multiethnic cohort. Nutr Cancer 58(2):136–145
    • (2007) Nutr Cancer , vol.58 , Issue.2 , pp. 136-145
    • Delellis Henderson, K.1    Rinaldi, S.2    Kaaks, R.3
  • 50
    • 0030682092 scopus 로고    scopus 로고
    • Milk intake and bone mineral acquisition in adolescent girls: randomised, controlled intervention trial
    • COI: 1:STN:280:DyaK1c%2FltFCruw%3D%3D, PID: 9390050
    • Cadogan J, Eastell R, Jones N et al (1997) Milk intake and bone mineral acquisition in adolescent girls: randomised, controlled intervention trial. BMJ 315(7118):1255–1260
    • (1997) BMJ , vol.315 , Issue.7118 , pp. 1255-1260
    • Cadogan, J.1    Eastell, R.2    Jones, N.3
  • 51
    • 0032836498 scopus 로고    scopus 로고
    • Dietary changes favorably affect bone remodeling in older adults
    • COI: 1:STN:280:DyaK1Mvlt1SitQ%3D%3D, PID: 10524386
    • Heaney RP, McCarron DA, Dawson-Hughes B et al (1999) Dietary changes favorably affect bone remodeling in older adults. J Am Diet Assoc 99(10):1228–1233
    • (1999) J Am Diet Assoc , vol.99 , Issue.10 , pp. 1228-1233
    • Heaney, R.P.1    McCarron, D.A.2    Dawson-Hughes, B.3
  • 52
    • 20544467733 scopus 로고    scopus 로고
    • Effects of school milk intervention on cortical bone accretion and indicators relevant to bone metabolism in Chinese girls aged 10–12 years in Beijing
    • COI: 1:CAS:528:DC%2BD2MXktlyksr4%3D, PID: 15883444
    • Zhu K, Du XQ, Cowell CT et al (2005) Effects of school milk intervention on cortical bone accretion and indicators relevant to bone metabolism in Chinese girls aged 10–12 years in Beijing. Am J Clin Nutr 81(5):1168–1175
    • (2005) Am J Clin Nutr , vol.81 , Issue.5 , pp. 1168-1175
    • Zhu, K.1    Du, X.Q.2    Cowell, C.T.3
  • 53
    • 4644297300 scopus 로고    scopus 로고
    • High intakes of skimmed milk, but not meat, increase serum IGF-I and IGFBP-3 in eight-year-old boys
    • COI: 1:CAS:528:DC%2BD2cXmvFGisro%3D, PID: 15054433
    • Hoppe C, Molgaard C, Juul A et al (2004) High intakes of skimmed milk, but not meat, increase serum IGF-I and IGFBP-3 in eight-year-old boys. Eur J Clin Nutr 58(9):1211–1216
    • (2004) Eur J Clin Nutr , vol.58 , Issue.9 , pp. 1211-1216
    • Hoppe, C.1    Molgaard, C.2    Juul, A.3
  • 54
    • 84885218672 scopus 로고    scopus 로고
    • Maternal milk consumption, birth size and adult height of offspring: a prospective cohort study with 20 years of follow-up
    • COI: 1:CAS:528:DC%2BC3sXhsFynu7jI, PID: 24002041
    • Hrolfsdottir L, Rytter D, Bech BH et al (2013) Maternal milk consumption, birth size and adult height of offspring: a prospective cohort study with 20 years of follow-up. Eur J Clin Nutr 67(10):1036–1041
    • (2013) Eur J Clin Nutr , vol.67 , Issue.10 , pp. 1036-1041
    • Hrolfsdottir, L.1    Rytter, D.2    Bech, B.H.3
  • 55
    • 84879815409 scopus 로고    scopus 로고
    • Animal protein intakes during early life and adolescence differ in their relation to the growth hormone-insulin-like-growth-factor axis in young adulthood
    • COI: 1:CAS:528:DC%2BC3sXhtVegtb%2FO, PID: 23700336
    • Joslowski G, Remer T, Assmann KE et al (2013) Animal protein intakes during early life and adolescence differ in their relation to the growth hormone-insulin-like-growth-factor axis in young adulthood. J Nutr 143(7):1147–1154
    • (2013) J Nutr , vol.143 , Issue.7 , pp. 1147-1154
    • Joslowski, G.1    Remer, T.2    Assmann, K.E.3
  • 56
    • 0034129836 scopus 로고    scopus 로고
    • Lifestyle factors and insulin-like growth factor 1 levels among elderly men
    • COI: 1:STN:280:DC%2BD3M%2FlsFeitw%3D%3D, PID: 10954256
    • Signorello LB, Kuper H, Lagiou P et al (2000) Lifestyle factors and insulin-like growth factor 1 levels among elderly men. Eur J Cancer Prev 9(3):173–178
    • (2000) Eur J Cancer Prev , vol.9 , Issue.3 , pp. 173-178
    • Signorello, L.B.1    Kuper, H.2    Lagiou, P.3
  • 57
    • 20544459377 scopus 로고    scopus 로고
    • Association of diet with serum insulin-like growth factor I in middle-aged and elderly men
    • COI: 1:CAS:528:DC%2BD2MXktlylu7c%3D, PID: 15883443
    • Larsson SC, Wolk K, Brismar K et al (2005) Association of diet with serum insulin-like growth factor I in middle-aged and elderly men. Am J Clin Nutr 81(5):1163–1167
    • (2005) Am J Clin Nutr , vol.81 , Issue.5 , pp. 1163-1167
    • Larsson, S.C.1    Wolk, K.2    Brismar, K.3
  • 58
    • 79959322549 scopus 로고    scopus 로고
    • IGFBP2 as an immunohistochemical marker for prostatic adenocarcinoma
    • COI: 1:CAS:528:DC%2BC3MXntF2isb0%3D, PID: 21304397
    • Ambrosini-Spaltro A, Farnedi A, Montironi R et al (2011) IGFBP2 as an immunohistochemical marker for prostatic adenocarcinoma. Appl Immunohistochem Mol Morphol 19(4):318–328
    • (2011) Appl Immunohistochem Mol Morphol , vol.19 , Issue.4 , pp. 318-328
    • Ambrosini-Spaltro, A.1    Farnedi, A.2    Montironi, R.3
  • 59
    • 84891375329 scopus 로고    scopus 로고
    • Relaxed imprinting of IGF2 in peripheral blood cells of patients with a history of prostate cancer
    • PID: 23781309
    • Belharazem D, Kirchner M, Geissler F et al (2012) Relaxed imprinting of IGF2 in peripheral blood cells of patients with a history of prostate cancer. Endocr Connect 1(2):87–94
    • (2012) Endocr Connect , vol.1 , Issue.2 , pp. 87-94
    • Belharazem, D.1    Kirchner, M.2    Geissler, F.3
  • 60
    • 80053180338 scopus 로고    scopus 로고
    • Insulin-like growth factor-2 (IGF2) loss of imprinting marks a field defect within human prostates containing cancer
    • COI: 1:CAS:528:DC%2BC3MXht1Srs7nI, PID: 21432864
    • Bhusari S, Yang B, Kueck J et al (2011) Insulin-like growth factor-2 (IGF2) loss of imprinting marks a field defect within human prostates containing cancer. Prostate 71(15):1621–1630
    • (2011) Prostate , vol.71 , Issue.15 , pp. 1621-1630
    • Bhusari, S.1    Yang, B.2    Kueck, J.3
  • 61
    • 0345392848 scopus 로고    scopus 로고
    • Insulin-like growth factor (IGF)-I, IGF-II and IGF type I receptor (IGFR-I) expression in prostatic cancer
    • Cardillo MR, Monti S, Di Silverio F et al: Insulin-like growth factor (IGF)-I, IGF-II and IGF type I receptor (IGFR-I) expression in prostatic cancer. Anticancer Res 2003, 23(5A):3825–3835
    • (2003) Anticancer Res , vol.23 , Issue.5A , pp. 3825-3835
    • Cardillo, M.R.1    Monti, S.2    Di Silverio, F.3
  • 62
    • 84878839065 scopus 로고    scopus 로고
    • Common variants in IGF1 pathway genes and clinical outcomes after radical prostatectomy
    • PID: 23397154
    • Chang CF, Pao JB, Yu CC et al (2013) Common variants in IGF1 pathway genes and clinical outcomes after radical prostatectomy. Ann Surg Oncol 20(7):2446–2452
    • (2013) Ann Surg Oncol , vol.20 , Issue.7 , pp. 2446-2452
    • Chang, C.F.1    Pao, J.B.2    Yu, C.C.3
  • 63
    • 0031897867 scopus 로고    scopus 로고
    • Differential expression of insulin-like growth factor binding proteins in high versus low Gleason score prostate cancer
    • COI: 1:CAS:528:DyaK1cXms1equ7Y%3D, PID: 9507888
    • Figueroa JA, De Raad S, Tadlock L et al (1998) Differential expression of insulin-like growth factor binding proteins in high versus low Gleason score prostate cancer. J Urol 159(4):1379–1383
    • (1998) J Urol , vol.159 , Issue.4 , pp. 1379-1383
    • Figueroa, J.A.1    De Raad, S.2    Tadlock, L.3
  • 64
    • 0032426137 scopus 로고    scopus 로고
    • Quantitative immunohistochemical analysis of insulin-like growth factor binding protein-3 in human prostatic adenocarcinoma: a prognostic study
    • COI: 1:CAS:528:DyaK1cXms1Olsr4%3D, PID: 9598573
    • Hampel OZ, Kattan MW, Yang G et al (1998) Quantitative immunohistochemical analysis of insulin-like growth factor binding protein-3 in human prostatic adenocarcinoma: a prognostic study. J Urol 159(6):2220–2225
    • (1998) J Urol , vol.159 , Issue.6 , pp. 2220-2225
    • Hampel, O.Z.1    Kattan, M.W.2    Yang, G.3
  • 65
    • 84865425492 scopus 로고    scopus 로고
    • Steroid hormone receptors, matrix metalloproteinases, insulin-like growth factor, and dystroglycans interactions in prostatic diseases in the elderly men
    • COI: 1:CAS:528:DC%2BC38Xht1ektLvI, PID: 22648746
    • Hetzl AC, Favaro WJ, Billis A et al (2012) Steroid hormone receptors, matrix metalloproteinases, insulin-like growth factor, and dystroglycans interactions in prostatic diseases in the elderly men. Microsc Res Tech 75(9):1197–1205
    • (2012) Microsc Res Tech , vol.75 , Issue.9 , pp. 1197-1205
    • Hetzl, A.C.1    Favaro, W.J.2    Billis, A.3
  • 66
    • 33644914726 scopus 로고    scopus 로고
    • Loss of heterozygosity of M6P/IGF2R gene is an early event in the development of prostate cancer
    • COI: 1:CAS:528:DC%2BD28XitFGiu78%3D, PID: 16304558
    • Hu CK, McCall S, Madden J et al (2006) Loss of heterozygosity of M6P/IGF2R gene is an early event in the development of prostate cancer. Prostate Cancer Prostatic Dis 9(1):62–67
    • (2006) Prostate Cancer Prostatic Dis , vol.9 , Issue.1 , pp. 62-67
    • Hu, C.K.1    McCall, S.2    Madden, J.3
  • 67
    • 85017875878 scopus 로고    scopus 로고
    • Impact of insulin-like growth factor (igf) kinetics on the development of prostate cancer: age-adjusted and baseline Psa-adjusted case control study
    • Ito K, Yamamoto T, Miyakubo M et al (2009) Impact of insulin-like growth factor (igf) kinetics on the development of prostate cancer: age-adjusted and baseline Psa-adjusted case control study. J Urol 181(4):658–658
    • (2009) J Urol , vol.181 , Issue.4 , pp. 658
    • Ito, K.1    Yamamoto, T.2    Miyakubo, M.3
  • 68
    • 33845701883 scopus 로고    scopus 로고
    • Comprehensive evaluation of genetic variation in the IGF1 gene and risk of prostate cancer
    • COI: 1:CAS:528:DC%2BD28XhtlGqsrbE, PID: 17096324
    • Johansson M, Mckay JD, Stattin P et al (2007) Comprehensive evaluation of genetic variation in the IGF1 gene and risk of prostate cancer. Int J Cancer 120(3):539–542
    • (2007) Int J Cancer , vol.120 , Issue.3 , pp. 539-542
    • Johansson, M.1    Mckay, J.D.2    Stattin, P.3
  • 69
    • 21844436530 scopus 로고    scopus 로고
    • Glutathione S-transferase M1 gene but not insulin-like growth factor-2 gene or epidermal growth factor gene is associated with prostate cancer
    • COI: 1:CAS:528:DC%2BD2MXmt1Wiu7Y%3D, PID: 16018936
    • Lai MT, Chen RH, Tsai FJ et al (2005) Glutathione S-transferase M1 gene but not insulin-like growth factor-2 gene or epidermal growth factor gene is associated with prostate cancer. Urol Oncol 23(4):225–229
    • (2005) Urol Oncol , vol.23 , Issue.4 , pp. 225-229
    • Lai, M.T.1    Chen, R.H.2    Tsai, F.J.3
  • 70
    • 0036227639 scopus 로고    scopus 로고
    • The relationship of circulating insulin-like growth factor 1, its binding protein-3, prostate-specific antigen and C-reactive protein with disease stage in prostate cancer
    • COI: 1:CAS:528:DC%2BD38XjtFaktrk%3D, PID: 11872031
    • Latif Z, McMillan DC, Wallace AM et al (2002) The relationship of circulating insulin-like growth factor 1, its binding protein-3, prostate-specific antigen and C-reactive protein with disease stage in prostate cancer. BJU Int 89(4):396–399
    • (2002) BJU Int , vol.89 , Issue.4 , pp. 396-399
    • Latif, Z.1    McMillan, D.C.2    Wallace, A.M.3
  • 71
    • 85017864786 scopus 로고    scopus 로고
    • Insulin-Like growth factor binding protein 3 (IGFBP-3) is up-regulated in prostatic adenocarcinoma (PAC) and correlates with gleason grade
    • Linos KD, Lu S, Ross JS et al (2009) Insulin-Like growth factor binding protein 3 (IGFBP-3) is up-regulated in prostatic adenocarcinoma (PAC) and correlates with gleason grade. Lab Invest 89:179A–179A
    • (2009) Lab Invest , vol.89 , pp. 179a
    • Linos, K.D.1    Lu, S.2    Ross, J.S.3
  • 72
    • 60849106232 scopus 로고    scopus 로고
    • [Genomic imprinting of insulin-like growth factor II in prostate cancer and its clinical significance]
    • COI: 1:CAS:528:DC%2BD2sXhtFyltLzI, PID: 16764778
    • Liu ZW, Zhou FJ, Luo YM et al (2006) [Genomic imprinting of insulin-like growth factor II in prostate cancer and its clinical significance]. Ai Zheng 25(6):765–770
    • (2006) Ai Zheng , vol.25 , Issue.6 , pp. 765-770
    • Liu, Z.W.1    Zhou, F.J.2    Luo, Y.M.3
  • 73
    • 81255124247 scopus 로고    scopus 로고
    • Expression of the IGF axis is decreased in local prostate cancer but enhanced after benign prostate epithelial differentiation and TGF-beta treatment
    • COI: 1:CAS:528:DC%2BC3MXhs12gt77E, PID: 21983635
    • Massoner P, Rennau ML, Heidegger I et al (2011) Expression of the IGF axis is decreased in local prostate cancer but enhanced after benign prostate epithelial differentiation and TGF-beta treatment. Am J Pathol 179(6):2905–2919
    • (2011) Am J Pathol , vol.179 , Issue.6 , pp. 2905-2919
    • Massoner, P.1    Rennau, M.L.2    Heidegger, I.3
  • 74
    • 0033796106 scopus 로고    scopus 로고
    • Expression of the insulin-like growth factor system and cancer progression in hormone-treated prostate cancer patients
    • COI: 1:CAS:528:DC%2BD3cXntlGhtrk%3D, PID: 11020056
    • Mita K, Nakahara M, Usui T (2000) Expression of the insulin-like growth factor system and cancer progression in hormone-treated prostate cancer patients. Int J Urol 7(9):321–329
    • (2000) Int J Urol , vol.7 , Issue.9 , pp. 321-329
    • Mita, K.1    Nakahara, M.2    Usui, T.3
  • 75
    • 76149086814 scopus 로고    scopus 로고
    • Plasma levels of acid-labile subunit, free insulin-like growth factor-I, and prostate cancer risk: A Prospective Study
    • COI: 1:CAS:528:DC%2BC3cXhs1eis7Y%3D
    • Mucci LA, Stark JR, Pollak MN et al (2010) Plasma levels of acid-labile subunit, free insulin-like growth factor-I, and prostate cancer risk: A Prospective Study. Cancer Epidemiol Biomark Prev 19(2):484–491
    • (2010) Cancer Epidemiol Biomark Prev , vol.19 , Issue.2 , pp. 484-491
    • Mucci, L.A.1    Stark, J.R.2    Pollak, M.N.3
  • 76
    • 33747374110 scopus 로고    scopus 로고
    • Methylation status of insulin-like growth factor-binding protein-3 promoter in prostate cancer tissues
    • Okugi H, Koike H, Sekine Y et al (2006) Methylation status of insulin-like growth factor-binding protein-3 promoter in prostate cancer tissues. Asia–Pac J Clin Oncol 2:144–149
    • (2006) Asia–Pac J Clin Oncol , vol.2 , pp. 144-149
    • Okugi, H.1    Koike, H.2    Sekine, Y.3
  • 77
    • 85017892931 scopus 로고    scopus 로고
    • IGF-axis and screen-detected prostate cancer: a cross-sectional study
    • Oliver SE, Jefferson K, Gunnell D et al (2003) IGF-axis and screen-detected prostate cancer: a cross-sectional study. J Urol 169(4):161–161
    • (2003) J Urol , vol.169 , Issue.4 , pp. 161
    • Oliver, S.E.1    Jefferson, K.2    Gunnell, D.3
  • 78
    • 67649443764 scopus 로고    scopus 로고
    • Aberrant epigenetic modifications in the CTCF binding domain of the IGF2/H19 gene in prostate cancer compared with benign prostate hyperplasia
    • COI: 1:CAS:528:DC%2BD1MXosFSmu7c%3D, PID: 19513555
    • Paradowska A, Fenic I, Konrad L et al (2009) Aberrant epigenetic modifications in the CTCF binding domain of the IGF2/H19 gene in prostate cancer compared with benign prostate hyperplasia. Int J Oncol 35(1):87–96
    • (2009) Int J Oncol , vol.35 , Issue.1 , pp. 87-96
    • Paradowska, A.1    Fenic, I.2    Konrad, L.3
  • 79
    • 34248546744 scopus 로고    scopus 로고
    • In silico mining identifies IGFBP3 as a novel target of methylation in prostate cancer
    • COI: 1:CAS:528:DC%2BD2sXlt1Kmurw%3D, PID: 17453001
    • Perry AS, Loftus B, Moroose R et al (2007) In silico mining identifies IGFBP3 as a novel target of methylation in prostate cancer. Br J Cancer 96(10):1587–1594
    • (2007) Br J Cancer , vol.96 , Issue.10 , pp. 1587-1594
    • Perry, A.S.1    Loftus, B.2    Moroose, R.3
  • 80
    • 0038364115 scopus 로고    scopus 로고
    • Overexpression of IGBFB2 is a marker for malignant transformation in prostate epithelium
    • COI: 1:CAS:528:DC%2BD3sXjtFKnt70%3D, PID: 12684767
    • Richardsen E, Ukkonen T, Bjornsen T et al (2003) Overexpression of IGBFB2 is a marker for malignant transformation in prostate epithelium. Virchows Arch 442(4):329–335
    • (2003) Virchows Arch , vol.442 , Issue.4 , pp. 329-335
    • Richardsen, E.1    Ukkonen, T.2    Bjornsen, T.3
  • 81
    • 84856722993 scopus 로고    scopus 로고
    • Serum insulin-like growth factors and mortality in localised and advanced clinically detected prostate cancer
    • PID: 22183619
    • Rowlands MA, Holly JMP, Hamdy F et al (2012) Serum insulin-like growth factors and mortality in localised and advanced clinically detected prostate cancer. Cancer Causes Control 23(2):347–354
    • (2012) Cancer Causes Control , vol.23 , Issue.2 , pp. 347-354
    • Rowlands, M.A.1    Holly, J.M.P.2    Hamdy, F.3
  • 82
    • 33847374107 scopus 로고    scopus 로고
    • Expression of insulin-like growth factor-1 receptor in local and metastatic prostate cancer
    • COI: 1:CAS:528:DC%2BD2sXivVSisLc%3D, PID: 17349528
    • Ryan CJ, Haqq CM, Simko J et al (2007) Expression of insulin-like growth factor-1 receptor in local and metastatic prostate cancer. Urol Oncol 25(2):134–140
    • (2007) Urol Oncol , vol.25 , Issue.2 , pp. 134-140
    • Ryan, C.J.1    Haqq, C.M.2    Simko, J.3
  • 83
    • 84881360817 scopus 로고    scopus 로고
    • IGF-IEc expression is associated with advanced clinical and pathological stage of prostate cancer
    • COI: 1:CAS:528:DC%2BC3sXhtVGltrrO, PID: 23749893
    • Savvani A, Petraki C, Msaouel P et al (2013) IGF-IEc expression is associated with advanced clinical and pathological stage of prostate cancer. Anticancer Res 33(6):2441–2445
    • (2013) Anticancer Res , vol.33 , Issue.6 , pp. 2441-2445
    • Savvani, A.1    Petraki, C.2    Msaouel, P.3
  • 84
    • 84872349394 scopus 로고    scopus 로고
    • IGFBP-3 nuclear localization predicts human prostate cancer recurrence
    • COI: 1:CAS:528:DC%2BC3sXnt12rtg%3D%3D, PID: 23011725
    • Seligson DB, Yu H, Tze S et al (2013) IGFBP-3 nuclear localization predicts human prostate cancer recurrence. Horm Cancer 4(1):12–23
    • (2013) Horm Cancer , vol.4 , Issue.1 , pp. 12-23
    • Seligson, D.B.1    Yu, H.2    Tze, S.3
  • 85
    • 0033831154 scopus 로고    scopus 로고
    • Correlation of preoperative plasma IGF-I levels with pathologic parameters and progression in patients undergoing radical prostatectomy
    • COI: 1:STN:280:DC%2BD3cvjsFGhtQ%3D%3D, PID: 10962307
    • Shariat SF, Bergamaschi F, Adler HL et al (2000) Correlation of preoperative plasma IGF-I levels with pathologic parameters and progression in patients undergoing radical prostatectomy. Urology 56(3):423–429
    • (2000) Urology , vol.56 , Issue.3 , pp. 423-429
    • Shariat, S.F.1    Bergamaschi, F.2    Adler, H.L.3
  • 86
    • 33845685422 scopus 로고    scopus 로고
    • Expression analysis of peptide growth factors VEGF, FGF2, TGFB1, EGF and IGF1 in prostate cancer and benign prostatic hyperplasia
    • COI: 1:CAS:528:DC%2BD28XotFKmtbc%3D, PID: 16820871
    • Soulitzis N, Karyotis I, Delakas D et al (2006) Expression analysis of peptide growth factors VEGF, FGF2, TGFB1, EGF and IGF1 in prostate cancer and benign prostatic hyperplasia. Int J Oncol 29(2):305–314
    • (2006) Int J Oncol , vol.29 , Issue.2 , pp. 305-314
    • Soulitzis, N.1    Karyotis, I.2    Delakas, D.3
  • 87
    • 0035051194 scopus 로고    scopus 로고
    • Leptin is associated with increased prostate cancer risk: a nested case-referent study
    • COI: 1:CAS:528:DC%2BD3MXitFWntbg%3D, PID: 11238530
    • Stattin P, Soderberg S, Hallmans G et al (2001) Leptin is associated with increased prostate cancer risk: a nested case-referent study. J Clin Endocrinol Metab 86(3):1341–1345
    • (2001) J Clin Endocrinol Metab , vol.86 , Issue.3 , pp. 1341-1345
    • Stattin, P.1    Soderberg, S.2    Hallmans, G.3
  • 88
    • 0029826841 scopus 로고    scopus 로고
    • Protein and messenger ribonucleic acid (mRNA) for the type 1 insulin-like growth factor (IGF) receptor is decreased and IGF-II mRNA is increased in human prostate carcinoma compared to benign prostate epithelium
    • COI: 1:CAS:528:DyaK28XmtlCmu7k%3D, PID: 8855837
    • Tennant MK, Thrasher JB, Twomey PA et al (1996) Protein and messenger ribonucleic acid (mRNA) for the type 1 insulin-like growth factor (IGF) receptor is decreased and IGF-II mRNA is increased in human prostate carcinoma compared to benign prostate epithelium. J Clin Endocrinol Metab 81(10):3774–3782
    • (1996) J Clin Endocrinol Metab , vol.81 , Issue.10 , pp. 3774-3782
    • Tennant, M.K.1    Thrasher, J.B.2    Twomey, P.A.3
  • 89
    • 0030071847 scopus 로고    scopus 로고
    • Immunohistochemical localization of insulin-like growth factor binding proteins 2 and 3 in prostate tissue: clinical correlations
    • COI: 1:STN:280:DyaK287msVKnuw%3D%3D, PID: 8583626
    • Thrasher JB, Tennant MK, Twomey PA et al (1996) Immunohistochemical localization of insulin-like growth factor binding proteins 2 and 3 in prostate tissue: clinical correlations. J Urol 155(3):999–1003
    • (1996) J Urol , vol.155 , Issue.3 , pp. 999-1003
    • Thrasher, J.B.1    Tennant, M.K.2    Twomey, P.A.3
  • 90
    • 84862640290 scopus 로고    scopus 로고
    • Analysis of imp3 expression in prostate adenocarcinomas
    • PID: 22627630
    • Tosun Yildirim H, Turk NS (2012) Analysis of imp3 expression in prostate adenocarcinomas. Turk Patoloji Derg 28:128–133
    • (2012) Turk Patoloji Derg , vol.28 , pp. 128-133
    • Tosun Yildirim, H.1    Turk, N.S.2
  • 91
    • 0030027259 scopus 로고    scopus 로고
    • Insulin-like growth factor-binding protein-2 and – 3 expression in benign human prostate epithelium, prostate intraepithelial neoplasia, and adenocarcinoma of the prostate
    • COI: 1:CAS:528:DyaK28XkvV2itg%3D%3D, PID: 8550786
    • Tennant MK, Thrasher JB, Twomey PA et al (1996) Insulin-like growth factor-binding protein-2 and – 3 expression in benign human prostate epithelium, prostate intraepithelial neoplasia, and adenocarcinoma of the prostate. J Clin Endocrinol Metab 81(1):411–420
    • (1996) J Clin Endocrinol Metab , vol.81 , Issue.1 , pp. 411-420
    • Tennant, M.K.1    Thrasher, J.B.2    Twomey, P.A.3
  • 92
    • 0033168795 scopus 로고    scopus 로고
    • Racial differences in insulin-like growth factor binding protein-3 in men at increased risk of prostate cancer
    • COI: 1:STN:280:DyaK1MzktFOitg%3D%3D, PID: 10414748
    • Tricoli JV, Winter DL, Hanlon AL et al (1999) Racial differences in insulin-like growth factor binding protein-3 in men at increased risk of prostate cancer. Urology 54(1):178–182
    • (1999) Urology , vol.54 , Issue.1 , pp. 178-182
    • Tricoli, J.V.1    Winter, D.L.2    Hanlon, A.L.3
  • 93
    • 84875338016 scopus 로고    scopus 로고
    • Insulin-like growth factor-1 genotypes and haplotypes influence the survival of prostate cancer patients with bone metastasis at initial diagnosis
    • COI: 1:CAS:528:DC%2BC3sXotVKitr8%3D, PID: 23530598
    • Tsuchiya N, Narita S, Inoue T et al (2013) Insulin-like growth factor-1 genotypes and haplotypes influence the survival of prostate cancer patients with bone metastasis at initial diagnosis. BMC Cancer 13:150
    • (2013) BMC Cancer , vol.13 , pp. 150
    • Tsuchiya, N.1    Narita, S.2    Inoue, T.3
  • 94
    • 33646458859 scopus 로고    scopus 로고
    • Impact of IGF-I and CYP19 gene polymorphisms on the survival of patients with metastatic prostate cancer
    • COI: 1:CAS:528:DC%2BD28Xlt1amurw%3D, PID: 16648498
    • Tsuchiya N, Wang L, Suzuki H et al (2006) Impact of IGF-I and CYP19 gene polymorphisms on the survival of patients with metastatic prostate cancer. J Clin Oncol 24(13):1982–1989
    • (2006) J Clin Oncol , vol.24 , Issue.13 , pp. 1982-1989
    • Tsuchiya, N.1    Wang, L.2    Suzuki, H.3
  • 95
    • 85017915413 scopus 로고    scopus 로고
    • Validating insulin-like growth factor (IGF)-1 and IGF binding protein (IGFBP)-3 as pertinent therapeutic targets for advanced prostate cancer
    • Tu SM, Kim J, Wang XM et al (2004) Validating insulin-like growth factor (IGF)-1 and IGF binding protein (IGFBP)-3 as pertinent therapeutic targets for advanced prostate cancer. J Bone Miner Res 19(9):1585–1585
    • (2004) J Bone Miner Res , vol.19 , Issue.9 , pp. 1585
    • Tu, S.M.1    Kim, J.2    Wang, X.M.3
  • 96
    • 79955411449 scopus 로고    scopus 로고
    • Serial analysis of resected prostate cancer suggests up-regulation of type 1 IGF receptor with disease progression
    • COI: 1:CAS:528:DC%2BC3MXns1Churw%3D, PID: 20840329
    • Turney BW, Turner GDH, Brewster SF et al (2011) Serial analysis of resected prostate cancer suggests up-regulation of type 1 IGF receptor with disease progression. BJU Int 107(9):1488–1499
    • (2011) BJU Int , vol.107 , Issue.9 , pp. 1488-1499
    • Turney, B.W.1    Turner, G.D.H.2    Brewster, S.F.3
  • 97
    • 85017889747 scopus 로고    scopus 로고
    • Relation of plasma IGF-1 and IGFBP-3 to the risk of prostate cancer
    • Woongeol Y, Kwanjin P, Seong Jin J et al (2007) Relation of plasma IGF-1 and IGFBP-3 to the risk of prostate cancer. Eur Urol Suppl 6(2):149–149
    • (2007) Eur Urol Suppl , vol.6 , Issue.2 , pp. 149
    • Woongeol, Y.1    Kwanjin, P.2    Seong Jin, J.3
  • 98
    • 0035111828 scopus 로고    scopus 로고
    • Levels of insulin-like growth factor 1 (IGF-I) and IGF binding proteins 2 and 3 in serial postoperative serum samples and risk of prostate cancer recurrence
    • COI: 1:STN:280:DC%2BD3M3islKiuw%3D%3D, PID: 11248622
    • Yu H, Nicar MR, Shi RH et al (2001) Levels of insulin-like growth factor 1 (IGF-I) and IGF binding proteins 2 and 3 in serial postoperative serum samples and risk of prostate cancer recurrence. Urol 57(3):471–475
    • (2001) Urol , vol.57 , Issue.3 , pp. 471-475
    • Yu, H.1    Nicar, M.R.2    Shi, R.H.3
  • 99
    • 84887272861 scopus 로고    scopus 로고
    • Protein expression of pten, insulin-like growth factor i receptor (igf-ir), and lethal prostate cancer: A Prospective Study
    • COI: 1:CAS:528:DC%2BC3sXhslartrrK
    • Zu K, Martin NE, Fiorentino M et al (2013) Protein expression of pten, insulin-like growth factor i receptor (igf-ir), and lethal prostate cancer: A Prospective Study. Cancer Epidemiol Biomark Prev 22(11):1984–1993
    • (2013) Cancer Epidemiol Biomark Prev , vol.22 , Issue.11 , pp. 1984-1993
    • Zu, K.1    Martin, N.E.2    Fiorentino, M.3
  • 100
    • 77955498341 scopus 로고    scopus 로고
    • A study of the single nucleotide polymorphism in seven genes (GHR, IGFBP3, IGFR1, IRS1, FMN1, ANXA2, TaGLN) in ethnic Russians and in patients with prostate cancer
    • Lisitskaia KV, Krakhmaleva IN, Shishkin SS (2010) A study of the single nucleotide polymorphism in seven genes (GHR, IGFBP3, IGFR1, IRS1, FMN1, ANXA2, TaGLN) in ethnic Russians and in patients with prostate cancer. Mol Gen Microbiol Virol 25(2):34–37
    • (2010) Mol Gen Microbiol Virol , vol.25 , Issue.2 , pp. 34-37
    • Lisitskaia, K.V.1    Krakhmaleva, I.N.2    Shishkin, S.S.3
  • 101
    • 0032540667 scopus 로고    scopus 로고
    • Insulin-like growth factor 1 and prostate cancer risk: a population-based, case-control study
    • COI: 1:CAS:528:DyaK1cXktFOqsLc%3D, PID: 9637140
    • Wolk A, Mantzoros CS, Andersson SO et al (1998) Insulin-like growth factor 1 and prostate cancer risk: a population-based, case-control study. J Natl Cancer Inst 90(12):911–915
    • (1998) J Natl Cancer Inst , vol.90 , Issue.12 , pp. 911-915
    • Wolk, A.1    Mantzoros, C.S.2    Andersson, S.O.3
  • 102
    • 0032820181 scopus 로고    scopus 로고
    • Insulin-like growth factor 1 (IGF-l), IGF-1 density, and IGF-1/PSA ratio for prostate cancer detection
    • COI: 1:STN:280:DyaK1MvjvV2gsA%3D%3D, PID: 10510914
    • Djavan B, Bursa B, Seitz C et al (1999) Insulin-like growth factor 1 (IGF-l), IGF-1 density, and IGF-1/PSA ratio for prostate cancer detection. Urology 54(4):603–606
    • (1999) Urology , vol.54 , Issue.4 , pp. 603-606
    • Djavan, B.1    Bursa, B.2    Seitz, C.3
  • 103
    • 0034046052 scopus 로고    scopus 로고
    • Analysis of relations between serum levels of epitestosterone, estradiol, testosterone, IGF-1 and prostatic specific antigen in men with benign prostatic hyperplasia and carcinoma of the prostate
    • COI: 1:CAS:528:DC%2BD3cXksVChu7c%3D, PID: 10984080
    • Hill M, Bilek R, Safarik L et al (2000) Analysis of relations between serum levels of epitestosterone, estradiol, testosterone, IGF-1 and prostatic specific antigen in men with benign prostatic hyperplasia and carcinoma of the prostate. Physiol Res 49:S113–S118
    • (2000) Physiol Res , vol.49 , pp. S113-S118
    • Hill, M.1    Bilek, R.2    Safarik, L.3
  • 104
    • 0034437042 scopus 로고    scopus 로고
    • The significance of PSA/IGF-1 ratio in differentiating benign prostate hyperplasia from prostate cancer
    • COI: 1:STN:280:DC%2BD3M3pvVKkug%3D%3D, PID: 11381196
    • Koliakos G, Chatzivasiliou D, Dimopoulos T et al (2000) The significance of PSA/IGF-1 ratio in differentiating benign prostate hyperplasia from prostate cancer. Dis Markers 16(3–4):143–146
    • (2000) Dis Markers , vol.16 , Issue.3-4 , pp. 143-146
    • Koliakos, G.1    Chatzivasiliou, D.2    Dimopoulos, T.3
  • 105
    • 0036896191 scopus 로고    scopus 로고
    • Insulin-like growth factor-1 and insulin-like growth factor binding protein-3 for prostate cancer detection in patients undergoing prostate biopsy
    • Ismail H, Pollak M, Behlouli H et al (2002) Insulin-like growth factor-1 and insulin-like growth factor binding protein-3 for prostate cancer detection in patients undergoing prostate biopsy. J Urol 168(6):2426–2430
    • (2002) J Urol , vol.168 , Issue.6 , pp. 2426-2430
    • Ismail, H.1    Pollak, M.2    Behlouli, H.3
  • 106
    • 0037304341 scopus 로고    scopus 로고
    • Serum insulin-like growth factor binding protein-3/prostate-specific antigen ratio is a useful predictive marker in patients with advanced prostate cancer
    • PID: 12497585
    • Miyata Y, Sakai H, Hayashi T (2003) Serum insulin-like growth factor binding protein-3/prostate-specific antigen ratio is a useful predictive marker in patients with advanced prostate cancer. Prostate 54(2):125–132
    • (2003) Prostate , vol.54 , Issue.2 , pp. 125-132
    • Miyata, Y.1    Sakai, H.2    Hayashi, T.3
  • 107
    • 0037441374 scopus 로고    scopus 로고
    • Serum human glandular kallikrein (hK2) and insulin-like growth factor I (IGF-I) improve the discrimination between prostate cancer and benign prostatic hyperplasia in combination with total and %free PSA
    • COI: 1:CAS:528:DC%2BD3sXhsFaju70%3D, PID: 12518327
    • Scorilas A, Plebani M, Mazza S et al (2003) Serum human glandular kallikrein (hK2) and insulin-like growth factor I (IGF-I) improve the discrimination between prostate cancer and benign prostatic hyperplasia in combination with total and %free PSA. Prostate 54(3):220–229
    • (2003) Prostate , vol.54 , Issue.3 , pp. 220-229
    • Scorilas, A.1    Plebani, M.2    Mazza, S.3
  • 108
    • 1642578163 scopus 로고    scopus 로고
    • Serum insulin-like growth factor-I and insulin-like growth factor-binding protein-3 in localized, metastasized prostate cancer and benign prostatic hyperplasia
    • COI: 1:CAS:528:DC%2BD2cXkt12msQ%3D%3D, PID: 14730168
    • Aksoy Y, Aksoy H, Bakan E et al (2004) Serum insulin-like growth factor-I and insulin-like growth factor-binding protein-3 in localized, metastasized prostate cancer and benign prostatic hyperplasia. Urol Int 72(1):62–65
    • (2004) Urol Int , vol.72 , Issue.1 , pp. 62-65
    • Aksoy, Y.1    Aksoy, H.2    Bakan, E.3
  • 109
    • 18544362817 scopus 로고    scopus 로고
    • Serum insulin-like growth factor-I levels and prostatic intraepithelial neoplasia: a clue to the relationship between IGF-I physiology and prostate cancer risk
    • COI: 1:CAS:528:DC%2BD2MXktFCkt7c%3D
    • Nam RK, Trachtenberg J, Jewett MAS et al (2005) Serum insulin-like growth factor-I levels and prostatic intraepithelial neoplasia: a clue to the relationship between IGF-I physiology and prostate cancer risk. Cancer Epidemiol Biomark Prev 14(5):1270–1273
    • (2005) Cancer Epidemiol Biomark Prev , vol.14 , Issue.5 , pp. 1270-1273
    • Nam, R.K.1    Trachtenberg, J.2    Jewett, M.A.S.3
  • 110
    • 32044469860 scopus 로고    scopus 로고
    • IGF-II serum levels increase discrimination between benign prostatic hyperplasia and prostate cancer and improve the predictive value of PSA in clinical staging
    • COI: 1:CAS:528:DC%2BD28Xis1OqtLY%3D, PID: 16386354
    • Trojan L, Bode C, Weiss C et al (2006) IGF-II serum levels increase discrimination between benign prostatic hyperplasia and prostate cancer and improve the predictive value of PSA in clinical staging. Eur Urol 49(2):286–292
    • (2006) Eur Urol , vol.49 , Issue.2 , pp. 286-292
    • Trojan, L.1    Bode, C.2    Weiss, C.3
  • 111
    • 40349112698 scopus 로고    scopus 로고
    • Serum measurements of testosterone, insulin-like growth factor 1, and insulin-like growth factor binding protein-3 in the diagnosis of prostate cancer among Korean men
    • COI: 1:CAS:528:DC%2BD1cXkt1Oqtrw%3D, PID: 18097534
    • Hong SK, Han BK, Jeong JS et al (2008) Serum measurements of testosterone, insulin-like growth factor 1, and insulin-like growth factor binding protein-3 in the diagnosis of prostate cancer among Korean men. Asian J Androl 10(2):207–213
    • (2008) Asian J Androl , vol.10 , Issue.2 , pp. 207-213
    • Hong, S.K.1    Han, B.K.2    Jeong, J.S.3
  • 112
    • 38349189488 scopus 로고    scopus 로고
    • Comparison of chromogranin A, insulin-like growth factor 1 and prostate-specific antigen serum markers in prostate adenocarcinoma and benign prostatic hyperplasia
    • COI: 1:CAS:528:DC%2BD1cXps1antw%3D%3D, PID: 18204237
    • Sciarra A, Gentile V, Monti S et al (2008) Comparison of chromogranin A, insulin-like growth factor 1 and prostate-specific antigen serum markers in prostate adenocarcinoma and benign prostatic hyperplasia. Urol Int 80(1):68–73
    • (2008) Urol Int , vol.80 , Issue.1 , pp. 68-73
    • Sciarra, A.1    Gentile, V.2    Monti, S.3
  • 113
    • 85017903514 scopus 로고    scopus 로고
    • Association between IGF-I and prostatitis, PIN III and prostate cancer diagnosis
    • Pina FM, Figueiredo G, Lunet N et al (2009) Association between IGF-I and prostatitis, PIN III and prostate cancer diagnosis. Urology 74(4):150
    • (2009) Urology , vol.74 , Issue.4 , pp. 150
    • Pina, F.M.1    Figueiredo, G.2    Lunet, N.3
  • 114
    • 77953633412 scopus 로고    scopus 로고
    • Serum level of IGFBP3 and IGF1/IGFBP3 molar ratio in addition to PSA and single nucleotide polymorphism in PSA and CYP17 gene may contribute to early diagnostics of prostate cancer
    • COI: 1:CAS:528:DC%2BC3cXnt1equ7c%3D, PID: 20099974
    • Tajtakova M, Pidanicova A, Valansky L et al (2010) Serum level of IGFBP3 and IGF1/IGFBP3 molar ratio in addition to PSA and single nucleotide polymorphism in PSA and CYP17 gene may contribute to early diagnostics of prostate cancer. Neoplasma 57(2):118–122
    • (2010) Neoplasma , vol.57 , Issue.2 , pp. 118-122
    • Tajtakova, M.1    Pidanicova, A.2    Valansky, L.3
  • 115
    • 80054894146 scopus 로고    scopus 로고
    • The correlation between zinc and insulin-like growth factor 1 (IGF-1), its binding protein (IGFBP-3) and prostate-specific antigen (PSA) in prostate cancer
    • COI: 1:CAS:528:DC%2BC3MXhsFOhsLzF, PID: 21671822
    • Darago A, Sapota A, Matych J et al (2011) The correlation between zinc and insulin-like growth factor 1 (IGF-1), its binding protein (IGFBP-3) and prostate-specific antigen (PSA) in prostate cancer. Clin Chem Lab Med 49(10):1699–1705
    • (2011) Clin Chem Lab Med , vol.49 , Issue.10 , pp. 1699-1705
    • Darago, A.1    Sapota, A.2    Matych, J.3
  • 116
    • 0035092756 scopus 로고    scopus 로고
    • Insulin-like growth factor I (IGF-I) and IGF-binding protein-3 in benign prostatic hyperplasia and prostate cancer
    • COI: 1:CAS:528:DC%2BD3MXht1Knt70%3D, PID: 11158033
    • Khosravi J, Diamandi A, Mistry J et al (2001) Insulin-like growth factor I (IGF-I) and IGF-binding protein-3 in benign prostatic hyperplasia and prostate cancer. J Clin Endocrinol Metab 86(2):694–699
    • (2001) J Clin Endocrinol Metab , vol.86 , Issue.2 , pp. 694-699
    • Khosravi, J.1    Diamandi, A.2    Mistry, J.3
  • 117
    • 0033871095 scopus 로고    scopus 로고
    • Low serum insulin-like growth factor 1 (IGF-1): a significant association with prostate cancer
    • COI: 1:STN:280:DC%2BD3M%2FmslWlsw%3D%3D, PID: 10963500
    • Baffa R, Reiss K, El-Gabry EA et al (2000) Low serum insulin-like growth factor 1 (IGF-1): a significant association with prostate cancer. Tech Urol 6(3):236–239
    • (2000) Tech Urol , vol.6 , Issue.3 , pp. 236-239
    • Baffa, R.1    Reiss, K.2    El-Gabry, E.A.3
  • 118
    • 0034527640 scopus 로고    scopus 로고
    • Serum levels of insulin-like growth factor I (IGF-I), IGF-II, IGF-binding protein-3, and prostate-specific antigen as predictors of clinical prostate cancer
    • COI: 1:CAS:528:DC%2BD3cXotlWmsrs%3D, PID: 11095464
    • Harman SM, Metter EJ, Blackman MR et al (2000) Serum levels of insulin-like growth factor I (IGF-I), IGF-II, IGF-binding protein-3, and prostate-specific antigen as predictors of clinical prostate cancer. J Clin Endocrinol Metab 85(11):4258–4265
    • (2000) J Clin Endocrinol Metab , vol.85 , Issue.11 , pp. 4258-4265
    • Harman, S.M.1    Metter, E.J.2    Blackman, M.R.3
  • 119
    • 0034614104 scopus 로고    scopus 로고
    • Plasma insulin-like growth factor-I, insulin-like growth factor-binding proteins, and prostate cancer risk: a Prospective Study
    • COI: 1:CAS:528:DC%2BD3cXptVehu7k%3D, PID: 11106682
    • Stattin P, Bylund A, Rinaldi S et al (2000) Plasma insulin-like growth factor-I, insulin-like growth factor-binding proteins, and prostate cancer risk: a Prospective Study. J Natl Cancer Inst 92(23):1910–1917
    • (2000) J Natl Cancer Inst , vol.92 , Issue.23 , pp. 1910-1917
    • Stattin, P.1    Bylund, A.2    Rinaldi, S.3
  • 120
    • 0344010575 scopus 로고    scopus 로고
    • Relation of serum insulin-like growth factor-I (IGF-I) and IGF binding protein-3 to risk of prostate cancer (United States)
    • PID: 14674736
    • Li L, Yu H, Schumacher F et al (2003) Relation of serum insulin-like growth factor-I (IGF-I) and IGF binding protein-3 to risk of prostate cancer (United States). Cancer Causes Control 14(8):721–726
    • (2003) Cancer Causes Control , vol.14 , Issue.8 , pp. 721-726
    • Li, L.1    Yu, H.2    Schumacher, F.3
  • 121
    • 0042173160 scopus 로고    scopus 로고
    • Serum insulin-like growth factor 1: tumor marker or etiologic factor? A prospective study of prostate cancer among Finnish men
    • COI: 1:CAS:528:DC%2BD3sXlsFOjurg%3D, PID: 12873996
    • Woodson K, Tangrea JA, Pollak M et al (2003) Serum insulin-like growth factor 1: tumor marker or etiologic factor? A prospective study of prostate cancer among Finnish men. Cancer Res 63(14):3991–3994
    • (2003) Cancer Res , vol.63 , Issue.14 , pp. 3991-3994
    • Woodson, K.1    Tangrea, J.A.2    Pollak, M.3
  • 122
    • 4544263472 scopus 로고    scopus 로고
    • Circulating free insulin-like growth factor (IGF)-I, total IGF-I, and IGF binding protein-3 levels do not predict the future risk to develop prostate cancer: results of a case-control study involving 201 patients within a population-based screening with a 4-year interval
    • COI: 1:CAS:528:DC%2BD2cXnslWhtrg%3D, PID: 15356036
    • Janssen JAMJL, Wildhagen MF, Ito K et al (2004) Circulating free insulin-like growth factor (IGF)-I, total IGF-I, and IGF binding protein-3 levels do not predict the future risk to develop prostate cancer: results of a case-control study involving 201 patients within a population-based screening with a 4-year interval. J Clin Endocrinol Metab 89(9):4391–4396
    • (2004) J Clin Endocrinol Metab , vol.89 , Issue.9 , pp. 4391-4396
    • Janssen, J.A.M.J.L.1    Wildhagen, M.F.2    Ito, K.3
  • 123
    • 4143057115 scopus 로고    scopus 로고
    • High levels of circulating insulin-like growth factor-I increase prostate cancer risk: a Prospective Study in a population-based nonscreened cohort
    • COI: 1:CAS:528:DC%2BD2cXpsVGrsrs%3D, PID: 15284261
    • Stattin P, Rinaldi S, Biessy C et al (2004) High levels of circulating insulin-like growth factor-I increase prostate cancer risk: a Prospective Study in a population-based nonscreened cohort. J Clin Oncol 22(15):3104–3112
    • (2004) J Clin Oncol , vol.22 , Issue.15 , pp. 3104-3112
    • Stattin, P.1    Rinaldi, S.2    Biessy, C.3
  • 124
    • 10844259063 scopus 로고    scopus 로고
    • Prostate carcinoma incidence in relation to prediagnostic circulating levels of insulin-like growth factor I, insulin-like growth factor binding protein 3, and insulin
    • COI: 1:CAS:528:DC%2BD2MXmtVarsg%3D%3D, PID: 15540247
    • Chen C, Lewis SK, Voigt L et al (2005) Prostate carcinoma incidence in relation to prediagnostic circulating levels of insulin-like growth factor I, insulin-like growth factor binding protein 3, and insulin. Cancer 103(1):76–84
    • (2005) Cancer , vol.103 , Issue.1 , pp. 76-84
    • Chen, C.1    Lewis, S.K.2    Voigt, L.3
  • 125
    • 27744550673 scopus 로고    scopus 로고
    • A prospective study of the insulin-like growth factor axis in relation with prostate cancer in the SU.VI.MAX trial
    • COI: 1:CAS:528:DC%2BD2MXhtVWgtbvJ
    • Meyer F, Galan P, Douville P et al (2005) A prospective study of the insulin-like growth factor axis in relation with prostate cancer in the SU.VI.MAX trial. Cancer Epidemiol Biomark Prev 14(9):2269–2272
    • (2005) Cancer Epidemiol Biomark Prev , vol.14 , Issue.9 , pp. 2269-2272
    • Meyer, F.1    Galan, P.2    Douville, P.3
  • 126
    • 21244456541 scopus 로고    scopus 로고
    • Plasma insulin-like growth factor-1 and binding protein-3 and subsequent risk of prostate cancer in the PSA era
    • PID: 15947877
    • Platz EA, Pollak MN, Leitzmann MF et al (2005) Plasma insulin-like growth factor-1 and binding protein-3 and subsequent risk of prostate cancer in the PSA era. Cancer Causes Control 16(3):255–262
    • (2005) Cancer Causes Control , vol.16 , Issue.3 , pp. 255-262
    • Platz, E.A.1    Pollak, M.N.2    Leitzmann, M.F.3
  • 127
    • 85017891955 scopus 로고    scopus 로고
    • CM: IGF-IR inibition induces MAPK signaling in prostate carcinoma cells
    • 71(8 (suppl)):2924
    • Morris BL, Young T, Van Golen CM: IGF-IR inibition induces MAPK signaling in prostate carcinoma cells. Cancer Res 2011, 71(8 (suppl)):2924 (Abstract)
    • (2011) Cancer Res
    • Morris, B.L.1    Young, T.2    Van Golen, C.M.3
  • 128
    • 34250887614 scopus 로고    scopus 로고
    • Serum insulin-like growth factor (IGF)-I and IGF-binding protein-3 concentrations and prostate cancer risk: results from the European prospective investigation into cancer and nutrition
    • COI: 1:CAS:528:DC%2BD2sXmtVKnt7w%3D
    • Allen NE, Key TJ, Appleby PN et al (2007) Serum insulin-like growth factor (IGF)-I and IGF-binding protein-3 concentrations and prostate cancer risk: results from the European prospective investigation into cancer and nutrition. Cancer Epidemiol Biomark Prev 16(6):1121–1127
    • (2007) Cancer Epidemiol Biomark Prev , vol.16 , Issue.6 , pp. 1121-1127
    • Allen, N.E.1    Key, T.J.2    Appleby, P.N.3
  • 129
    • 34548770084 scopus 로고    scopus 로고
    • Hypoxia-inducible factor-1alpha (HIF-1alpha) gene polymorphisms, circulating insulin-like growth factor binding protein (IGFBP)-3 levels and prostate cancer
    • COI: 1:CAS:528:DC%2BD2sXhtFGgtLbL, PID: 17624927
    • Li H, Bubley GJ, Balk SP et al (2007) Hypoxia-inducible factor-1alpha (HIF-1alpha) gene polymorphisms, circulating insulin-like growth factor binding protein (IGFBP)-3 levels and prostate cancer. Prostate 67(12):1354–1361
    • (2007) Prostate , vol.67 , Issue.12 , pp. 1354-1361
    • Li, H.1    Bubley, G.J.2    Balk, S.P.3
  • 130
    • 35348831817 scopus 로고    scopus 로고
    • IGF-1 and IGFBP-3: Risk of prostate cancer among men in the prostate, lung, colorectal and ovarian cancer screening trial
    • COI: 1:CAS:528:DC%2BD2sXht1aisL%2FP, PID: 17597108
    • Weiss JM, Huang WY, Rinaldi S et al (2007) IGF-1 and IGFBP-3: Risk of prostate cancer among men in the prostate, lung, colorectal and ovarian cancer screening trial. Int J Cancer 121(10):2267–2273
    • (2007) Int J Cancer , vol.121 , Issue.10 , pp. 2267-2273
    • Weiss, J.M.1    Huang, W.Y.2    Rinaldi, S.3
  • 131
    • 77957348937 scopus 로고    scopus 로고
    • Prostate cancer risk in relation to insulin-like growth factor (IGF)-I and IGF-binding protein-3: A Nested Case-Control Study in Large Scale Cohort Study in Japan (JACC Study)
    • PID: 20553083
    • Mikami K, Ozasa K, Nakao M et al (2009) Prostate cancer risk in relation to insulin-like growth factor (IGF)-I and IGF-binding protein-3: A Nested Case-Control Study in Large Scale Cohort Study in Japan (JACC Study). Asian Pac J Cancer Prev 10:57–61
    • (2009) Asian Pac J Cancer Prev , vol.10 , pp. 57-61
    • Mikami, K.1    Ozasa, K.2    Nakao, M.3
  • 132
    • 78649882351 scopus 로고    scopus 로고
    • Plasma insulin-like growth factor 1 is positively associated with low-grade prostate cancer in the Health Professionals Follow-up Study 1993–2004
    • COI: 1:CAS:528:DC%2BC3cXhsVOktL%2FO, PID: 20473871
    • Nimptsch K, Platz EA, Pollak MN et al (2011) Plasma insulin-like growth factor 1 is positively associated with low-grade prostate cancer in the Health Professionals Follow-up Study 1993–2004. Int J Cancer 128(3):660–667
    • (2011) Int J Cancer , vol.128 , Issue.3 , pp. 660-667
    • Nimptsch, K.1    Platz, E.A.2    Pollak, M.N.3
  • 133
    • 84866183841 scopus 로고    scopus 로고
    • Insulin-like growth factor-i concentration and risk of prostate cancer: results from the European prospective investigation into cancer and nutrition
    • COI: 1:CAS:528:DC%2BC38XhtlamtrfF
    • Price AJ, Allen NE, Appleby PN et al (2012) Insulin-like growth factor-i concentration and risk of prostate cancer: results from the European prospective investigation into cancer and nutrition. Cancer Epidemiol Biomark Prev 21(9):1531–1541
    • (2012) Cancer Epidemiol Biomark Prev , vol.21 , Issue.9 , pp. 1531-1541
    • Price, A.J.1    Allen, N.E.2    Appleby, P.N.3
  • 134
    • 84891515443 scopus 로고    scopus 로고
    • Variant NKX3.1 and Serum IGF-1: investigation of interaction in prostate cancer
    • PID: 24386513
    • Muhlbradt E, Ma J, Severi G et al (2013) Variant NKX3.1 and Serum IGF-1: investigation of interaction in prostate cancer. Genes Cancer 4(11–12):535–545
    • (2013) Genes Cancer , vol.4 , Issue.11-12 , pp. 535-545
    • Muhlbradt, E.1    Ma, J.2    Severi, G.3
  • 135
    • 0027413596 scopus 로고
    • Elevated levels of insulin-like growth factor-binding protein-2 in the serum of prostate-cancer patients
    • COI: 1:STN:280:DyaK3s3jt1Whuw%3D%3D, PID: 7682560
    • Cohen P, Peehl DM, Stamey TA et al (1993) Elevated levels of insulin-like growth factor-binding protein-2 in the serum of prostate-cancer patients. J Clin Endocrinol Metab 76(4):1031–1035
    • (1993) J Clin Endocrinol Metab , vol.76 , Issue.4 , pp. 1031-1035
    • Cohen, P.1    Peehl, D.M.2    Stamey, T.A.3
  • 136
    • 0030799934 scopus 로고    scopus 로고
    • Insulin-like growth factor 1 in relation to prostate cancer and benign prostatic hyperplasia
    • COI: 1:STN:280:DyaK1c%2FjtVCgug%3D%3D, PID: 9365156
    • Mantzoros CS, Tzonou A, Signorello LB et al (1997) Insulin-like growth factor 1 in relation to prostate cancer and benign prostatic hyperplasia. Br J Cancer 76(9):1115–1118
    • (1997) Br J Cancer , vol.76 , Issue.9 , pp. 1115-1118
    • Mantzoros, C.S.1    Tzonou, A.2    Signorello, L.B.3
  • 137
    • 0033579132 scopus 로고    scopus 로고
    • Insulin-like growth factor-binding protein-1 and prostate cancer
    • COI: 1:CAS:528:DyaK1MXotVaitro%3D, PID: 10564682
    • Signorello LB, Brismar K, Bergstrom R et al (1999) Insulin-like growth factor-binding protein-1 and prostate cancer. J Natl Cancer Inst 91(22):1965–1967
    • (1999) J Natl Cancer Inst , vol.91 , Issue.22 , pp. 1965-1967
    • Signorello, L.B.1    Brismar, K.2    Bergstrom, R.3
  • 138
    • 17744364495 scopus 로고    scopus 로고
    • Insulin-like growth factor I is not a useful marker of prostate cancer in men with elevated levels of prostate-specific antigen
    • COI: 1:CAS:528:DC%2BD3cXnslahsro%3D, PID: 10946875
    • Finne P, Auvinen A, Koistinen H et al (2000) Insulin-like growth factor I is not a useful marker of prostate cancer in men with elevated levels of prostate-specific antigen. J Clin Endocrinol Metab 85(8):2744–2747
    • (2000) J Clin Endocrinol Metab , vol.85 , Issue.8 , pp. 2744-2747
    • Finne, P.1    Auvinen, A.2    Koistinen, H.3
  • 139
    • 0033984872 scopus 로고    scopus 로고
    • The significance of serum levels of insulin-like growth factor-1 in patients with prostate cancer
    • COI: 1:CAS:528:DC%2BD3cXptVKrsQ%3D%3D, PID: 10619960
    • Kurek R, Tunn UW, Eckart O et al (2000) The significance of serum levels of insulin-like growth factor-1 in patients with prostate cancer. BJU Int 85(1):125–129
    • (2000) BJU Int , vol.85 , Issue.1 , pp. 125-129
    • Kurek, R.1    Tunn, U.W.2    Eckart, O.3
  • 140
    • 0034793466 scopus 로고    scopus 로고
    • Null association between insulin-like growth factors, insulin-like growth factor-binding proteins, and prostate cancer in a prospective study
    • COI: 1:CAS:528:DC%2BD3MXotVykurw%3D
    • Lacey JV, Hsing AW, Fillmore CM et al (2001) Null association between insulin-like growth factors, insulin-like growth factor-binding proteins, and prostate cancer in a prospective study. Cancer Epidemiol Biomark Prev 10(10):1101–1102
    • (2001) Cancer Epidemiol Biomark Prev , vol.10 , Issue.10 , pp. 1101-1102
    • Lacey, J.V.1    Hsing, A.W.2    Fillmore, C.M.3
  • 141
    • 0034916063 scopus 로고    scopus 로고
    • Insulin-like growth factors and prostate cancer: a population-based case-control study in China
    • COI: 1:CAS:528:DC%2BD3MXktlClu74%3D
    • Chokkalingam AP, Pollak M, Fillmore CM et al (2001) Insulin-like growth factors and prostate cancer: a population-based case-control study in China. Cancer Epidemiol Biomark Prev 10(5):421–427
    • (2001) Cancer Epidemiol Biomark Prev , vol.10 , Issue.5 , pp. 421-427
    • Chokkalingam, A.P.1    Pollak, M.2    Fillmore, C.M.3
  • 142
    • 85017910763 scopus 로고    scopus 로고
    • Significance of determination of serum insulin-like growth factor 1 (IGF- I) in prostate cancer
    • Li L, Liu J, Anwu T: Significance of determination of serum insulin-like growth factor 1 (IGF- I) in prostate cancer. Tianjin: Tianjin-shi Tixue She 2001.
    • (2001) Tianjin: Tianjin-shi Tixue She
    • Li, L.1    Liu, J.2    Anwu, T.3
  • 143
    • 9144269886 scopus 로고    scopus 로고
    • Screen-detected prostate cancer and the insulin-like growth factor axis: results of a Population-Based Case-Control Study
    • COI: 1:CAS:528:DC%2BD2cXht1CitLs%3D, PID: 14712493
    • Oliver SE, Gunnell D, Donovan J et al (2004) Screen-detected prostate cancer and the insulin-like growth factor axis: results of a Population-Based Case-Control Study. Int J Cancer 108(6):887–892
    • (2004) Int J Cancer , vol.108 , Issue.6 , pp. 887-892
    • Oliver, S.E.1    Gunnell, D.2    Donovan, J.3
  • 144
    • 20644457711 scopus 로고    scopus 로고
    • Insulin-like growth factor 1, chromogranin A and prostate specific antigen serum levels in prostate cancer patients and controls
    • COI: 1:CAS:528:DC%2BD2MXntVGktbs%3D, PID: 15967249
    • Marszalek M, Wachter J, Ponholzer A et al (2005) Insulin-like growth factor 1, chromogranin A and prostate specific antigen serum levels in prostate cancer patients and controls. Eur Urol 48(1):34–39
    • (2005) Eur Urol , vol.48 , Issue.1 , pp. 34-39
    • Marszalek, M.1    Wachter, J.2    Ponholzer, A.3
  • 145
    • 35148882966 scopus 로고    scopus 로고
    • IGF-1 and IGFBP-3 gene variants influence on serum levels and prostate cancer risk in African-Americans
    • COI: 1:CAS:528:DC%2BD2sXhtFeqsLzF, PID: 17724372
    • Hernandez W, Grenade C, Santos ER et al (2007) IGF-1 and IGFBP-3 gene variants influence on serum levels and prostate cancer risk in African-Americans. Carcinogenesis 28(10):2154–2159
    • (2007) Carcinogenesis , vol.28 , Issue.10 , pp. 2154-2159
    • Hernandez, W.1    Grenade, C.2    Santos, E.R.3
  • 146
    • 34347331093 scopus 로고    scopus 로고
    • Serum insulin-like growth factor I/free prostate specific antigen (IGF-I/fPSA) ratio enhances prostate cancer detection in men with total PSA 4.0–10.0ng/ml
    • COI: 1:CAS:528:DC%2BD2sXosVehs7o%3D
    • Zhao ZG, Liu JM, Li S et al (2007) Serum insulin-like growth factor I/free prostate specific antigen (IGF-I/fPSA) ratio enhances prostate cancer detection in men with total PSA 4.0–10.0 ng/ml. J Surg Oncol 96(1):54–61
    • (2007) J Surg Oncol , vol.96 , Issue.1 , pp. 54-61
    • Zhao, Z.G.1    Liu, J.M.2    Li, S.3
  • 147
    • 38849153431 scopus 로고    scopus 로고
    • Prostate cancer risk in relation to insulin-like growth factor (IGF)-I and IGF-binding protein-3: a Prospective Multiethnic Study
    • COI: 1:CAS:528:DC%2BD1cXmt12huw%3D%3D
    • Borugian MJ, Spinelli JJ, Sun Z et al (2008) Prostate cancer risk in relation to insulin-like growth factor (IGF)-I and IGF-binding protein-3: a Prospective Multiethnic Study. Cancer Epidemiol Biomark Prev 17(1):252–254
    • (2008) Cancer Epidemiol Biomark Prev , vol.17 , Issue.1 , pp. 252-254
    • Borugian, M.J.1    Spinelli, J.J.2    Sun, Z.3
  • 148
    • 68449084670 scopus 로고    scopus 로고
    • Plasma insulin-like growth factor-1 (IGF-1), IGF-binding protein-3, and the risk of prostate cancer: a Matched Case-Control Study in a Korean population
    • Kim JH, Park KJ, Bae J-B et al (2009) Plasma insulin-like growth factor-1 (IGF-1), IGF-binding protein-3, and the risk of prostate cancer: a Matched Case-Control Study in a Korean population. Korean J Urol 50(7):645–648
    • (2009) Korean J Urol , vol.50 , Issue.7 , pp. 645-648
    • Kim, J.H.1    Park, K.J.2    Bae, J.-B.3
  • 149
    • 67650911917 scopus 로고    scopus 로고
    • Genetic and plasma variation of insulin-like growth factor binding proteins in relation to prostate cancer incidence and survival
    • COI: 1:CAS:528:DC%2BD1MXhtFChsb%2FL, PID: 19455605
    • Johansson M, McKay JD, Rinaldi S et al (2009) Genetic and plasma variation of insulin-like growth factor binding proteins in relation to prostate cancer incidence and survival. Prostate 69(12):1281–1291
    • (2009) Prostate , vol.69 , Issue.12 , pp. 1281-1291
    • Johansson, M.1    McKay, J.D.2    Rinaldi, S.3
  • 150
    • 77952318705 scopus 로고    scopus 로고
    • Androgens, growth factors, and risk of prostate cancer: the multiethnic cohort
    • COI: 1:CAS:528:DC%2BC3cXnvFGqsLs%3D, PID: 20166103
    • Gill JK, Wilkens LR, Pollak MN et al (2010) Androgens, growth factors, and risk of prostate cancer: the multiethnic cohort. Prostate 70(8):906–915
    • (2010) Prostate , vol.70 , Issue.8 , pp. 906-915
    • Gill, J.K.1    Wilkens, L.R.2    Pollak, M.N.3
  • 151
    • 85017891684 scopus 로고    scopus 로고
    • The joint association of plasma 1, 25-dihydroxyvitamin D3 and IGFBP-3 levels and VDR FOK1 polymorphism with prostate cancer risk in Korean men
    • Kim JH, Lee SW, Jeong SJ et al (2010) The joint association of plasma 1, 25-dihydroxyvitamin D3 and IGFBP-3 levels and VDR FOK1 polymorphism with prostate cancer risk in Korean men. Eur Urol Suppl 9(2):243
    • (2010) Eur Urol Suppl , vol.9 , Issue.2 , pp. 243
    • Kim, J.H.1    Lee, S.W.2    Jeong, S.J.3
  • 152
    • 77952744178 scopus 로고    scopus 로고
    • Influence of IGFBP3 gene polymorphisms on IGFBP3 serum levels and the risk of prostate cancer in low-risk Korean men
    • 75(6)
    • Park K, Kim JH, Jeon HG et al: Influence of IGFBP3 gene polymorphisms on IGFBP3 serum levels and the risk of prostate cancer in low-risk Korean men. Urology 2010, 75(6)
    • (2010) Urology
    • Park, K.1    Kim, J.H.2    Jeon, H.G.3
  • 153
    • 79251596084 scopus 로고    scopus 로고
    • Genetic variability of the fatty acid synthase pathway is not associated with prostate cancer risk in the European prospective investigation on cancer (EPIC)
    • COI: 1:CAS:528:DC%2BC3MXhtlSqsr0%3D, PID: 20965718
    • Campa D, Husing A, Chang-Claude J et al (2011) Genetic variability of the fatty acid synthase pathway is not associated with prostate cancer risk in the European prospective investigation on cancer (EPIC). Eur J Cancer 47(3):420–427
    • (2011) Eur J Cancer , vol.47 , Issue.3 , pp. 420-427
    • Campa, D.1    Husing, A.2    Chang-Claude, J.3
  • 154
    • 84874496227 scopus 로고    scopus 로고
    • Insulin-like growth factors and insulin-like growth factor-binding proteins and prostate cancer risk: results from the prostate cancer prevention trial
    • COI: 1:CAS:528:DC%2BC3sXitlWisbw%3D
    • Neuhouser ML, Platz EA, Till C et al (2013) Insulin-like growth factors and insulin-like growth factor-binding proteins and prostate cancer risk: results from the prostate cancer prevention trial. Cancer Prev Res 6(2):91–99
    • (2013) Cancer Prev Res , vol.6 , Issue.2 , pp. 91-99
    • Neuhouser, M.L.1    Platz, E.A.2    Till, C.3
  • 155
    • 0032559272 scopus 로고    scopus 로고
    • Plasma insulin-like growth factor I and prostate cancer risk: a prospective study
    • COI: 1:CAS:528:DyaK1cXotVOqsg%3D%3D, PID: 9438850
    • Chan JM, Stampfer MJ, Giovannucci E et al (1998) Plasma insulin-like growth factor I and prostate cancer risk: a prospective study. Science 279(5350):563–566
    • (1998) Science , vol.279 , Issue.5350 , pp. 563-566
    • Chan, J.M.1    Stampfer, M.J.2    Giovannucci, E.3
  • 156
    • 12444253866 scopus 로고    scopus 로고
    • Interrelationships between plasma testosterone, SHBG, IGF-I, insulin and leptin in prostate cancer cases and controls
    • COI: 1:STN:280:DC%2BD3szltVOmsw%3D%3D, PID: 12883384
    • Kaaks R, Lukanova A, Rinaldi S et al (2003) Interrelationships between plasma testosterone, SHBG, IGF-I, insulin and leptin in prostate cancer cases and controls. Eur J Cancer Prev 12(4):309–315
    • (2003) Eur J Cancer Prev , vol.12 , Issue.4 , pp. 309-315
    • Kaaks, R.1    Lukanova, A.2    Rinaldi, S.3
  • 157
    • 0035217580 scopus 로고    scopus 로고
    • Ratios of IGF-I, IGF binding protein-3, and prostate-specific antigen in prostate cancer detection
    • COI: 1:CAS:528:DC%2BD3MXptVylur0%3D, PID: 11739433
    • Stattin P, Stenman UH, Riboli E et al (2001) Ratios of IGF-I, IGF binding protein-3, and prostate-specific antigen in prostate cancer detection. J Clin Endocrinol Metab 86(12):5745–5748
    • (2001) J Clin Endocrinol Metab , vol.86 , Issue.12 , pp. 5745-5748
    • Stattin, P.1    Stenman, U.H.2    Riboli, E.3
  • 158
    • 0037125383 scopus 로고    scopus 로고
    • Insulin-like growth factor-I (IGF-I) and IGF binding protein-3 as predictors of advanced-stage prostate cancer
    • COI: 1:CAS:528:DC%2BD38Xmt1Wlt70%3D, PID: 12122101
    • Chan JM, Stampfer MJ, Ma J et al (2002) Insulin-like growth factor-I (IGF-I) and IGF binding protein-3 as predictors of advanced-stage prostate cancer. J Natl Cancer Inst 94(14):1099–1106
    • (2002) J Natl Cancer Inst , vol.94 , Issue.14 , pp. 1099-1106
    • Chan, J.M.1    Stampfer, M.J.2    Ma, J.3
  • 159
    • 78549247522 scopus 로고    scopus 로고
    • Eighteen insulin-like growth factor pathway genes, circulating levels of IGF-I and its binding protein, and risk of prostate and breast cancer
    • COI: 1:CAS:528:DC%2BC3cXhtl2rsLfE
    • Gu FY, Schumacher FR, Canzian F et al (2010) Eighteen insulin-like growth factor pathway genes, circulating levels of IGF-I and its binding protein, and risk of prostate and breast cancer. Cancer Epidemiol Biomark Prev 19(11):2877–2887
    • (2010) Cancer Epidemiol Biomark Prev , vol.19 , Issue.11 , pp. 2877-2887
    • Gu, F.Y.1    Schumacher, F.R.2    Canzian, F.3
  • 160
    • 84860635417 scopus 로고    scopus 로고
    • Interactions between genome-wide significant genetic variants and circulating concentrations of insulin-like growth factor 1, sex hormones, and binding proteins in relation to prostate cancer risk in the national cancer institute breast and prostate cancer cohort consortium
    • PID: 22459122
    • Tsilidis KK, Travis RC, Appleby PN et al (2012) Interactions between genome-wide significant genetic variants and circulating concentrations of insulin-like growth factor 1, sex hormones, and binding proteins in relation to prostate cancer risk in the national cancer institute breast and prostate cancer cohort consortium. Am J Epidemiol 175(9):926–935
    • (2012) Am J Epidemiol , vol.175 , Issue.9 , pp. 926-935
    • Tsilidis, K.K.1    Travis, R.C.2    Appleby, P.N.3
  • 161
    • 0037468138 scopus 로고    scopus 로고
    • Polymorphism of the insulin gene is associated with increased prostate cancer risk
    • COI: 1:CAS:528:DC%2BD3sXhsV2rtb0%3D, PID: 12610512
    • Ho GYF, Melman A, Liu SM et al (2003) Polymorphism of the insulin gene is associated with increased prostate cancer risk. Br J Cancer 88(2):263–269
    • (2003) Br J Cancer , vol.88 , Issue.2 , pp. 263-269
    • Ho, G.Y.F.1    Melman, A.2    Liu, S.M.3
  • 162
    • 0041589477 scopus 로고    scopus 로고
    • Insulin-like growth factor-binding protein-3 gene-202A/C polymorphism is correlated with advanced disease status in prostate cancer
    • COI: 1:CAS:528:DC%2BD3sXmtFeku7Y%3D, PID: 12907612
    • Wang LZ, Habuchi T, Tsuchiya N et al (2003) Insulin-like growth factor-binding protein-3 gene-202 A/C polymorphism is correlated with advanced disease status in prostate cancer. Cancer Res 63(15):4407–4411
    • (2003) Cancer Res , vol.63 , Issue.15 , pp. 4407-4411
    • Wang, L.Z.1    Habuchi, T.2    Tsuchiya, N.3
  • 163
    • 2442679361 scopus 로고    scopus 로고
    • No association between genetic Polymorphisms in 1GF-1 and IGFBP-3 and prostate cancer
    • Li L, Cicek MS, Casey G et al (2004) No association between genetic Polymorphisms in 1GF-1 and IGFBP-3 and prostate cancer. Cancer Epidemiol Biomark Prev 13(3):497–498
    • (2004) Cancer Epidemiol Biomark Prev , vol.13 , Issue.3 , pp. 497-498
    • Li, L.1    Cicek, M.S.2    Casey, G.3
  • 164
    • 24944531217 scopus 로고    scopus 로고
    • IGF-I and IGFBP-3 polymorphisms and risk of prostate cancer
    • COI: 1:CAS:528:DC%2BD2MXhtFSns73I, PID: 15800934
    • Friedrichsen DM, Hawley S, Shu J et al (2005) IGF-I and IGFBP-3 polymorphisms and risk of prostate cancer. Prostate 65(1):44–51
    • (2005) Prostate , vol.65 , Issue.1 , pp. 44-51
    • Friedrichsen, D.M.1    Hawley, S.2    Shu, J.3
  • 165
    • 21644468050 scopus 로고    scopus 로고
    • CA repeat polymorphism in the insulin-like growth factor-I gene is associated with increased risk of prostate cancer and benign prostatic hyperplasia
    • COI: 1:CAS:528:DC%2BD2MXmsFWhtA%3D%3D, PID: 15586244
    • Tsuchiya N, Wang LH, Horikawa Y et al (2005) CA repeat polymorphism in the insulin-like growth factor-I gene is associated with increased risk of prostate cancer and benign prostatic hyperplasia. Int J Oncol 26(1):225–231
    • (2005) Int J Oncol , vol.26 , Issue.1 , pp. 225-231
    • Tsuchiya, N.1    Wang, L.H.2    Horikawa, Y.3
  • 166
    • 33846007250 scopus 로고    scopus 로고
    • Prostate cancer risk in relation to selected genetic polymorphisms in insulin-like growth factor-1, insulin-like growth factor binding protein-3, and insulin-like growth factor-I receptor
    • COI: 1:CAS:528:DC%2BD28XhtlCrtrvI
    • Chen C, Freeman R, Voigt LF et al (2006) Prostate cancer risk in relation to selected genetic polymorphisms in insulin-like growth factor-1, insulin-like growth factor binding protein-3, and insulin-like growth factor-I receptor. Cancer Epidemiol Biomark Prev 15(12):2461–2466
    • (2006) Cancer Epidemiol Biomark Prev , vol.15 , Issue.12 , pp. 2461-2466
    • Chen, C.1    Freeman, R.2    Voigt, L.F.3
  • 167
    • 34447522001 scopus 로고    scopus 로고
    • Grade-specific prostate cancer associations of IGF1(CA)(19) repeats and IGFBP3-202A/C in Blacks and whites
    • PID: 17668637
    • Hoyo C, Grubber J, Demark-Wahnefried W et al (2007) Grade-specific prostate cancer associations of IGF1(CA)(19) repeats and IGFBP3-202A/C in Blacks and whites. J Natl Med Assoc 99(7):718–722
    • (2007) J Natl Med Assoc , vol.99 , Issue.7 , pp. 718-722
    • Hoyo, C.1    Grubber, J.2    Demark-Wahnefried, W.3
  • 168
    • 77958190951 scopus 로고    scopus 로고
    • A comprehensive analysis of common IGF1, IGFBP1 and IGFBP3 genetic variation with prospective IGF-I and IGFBP-3 blood levels and prostate cancer risk among
    • COI: 1:CAS:528:DC%2BC3cXhtVahsLbL, PID: 20484221
    • Schumacher FR, Cheng I, Freedman ML et al (2010) A comprehensive analysis of common IGF1, IGFBP1 and IGFBP3 genetic variation with prospective IGF-I and IGFBP-3 blood levels and prostate cancer risk among. Hum Mol Genet 19(15):3089–3101
    • (2010) Hum Mol Genet , vol.19 , Issue.15 , pp. 3089-3101
    • Schumacher, F.R.1    Cheng, I.2    Freedman, M.L.3
  • 169
    • 20344390516 scopus 로고    scopus 로고
    • Prostate cancer risk and IRS1, IRS2, IGF1, and INS polymorphisms: Strong association of IRS1 G972R variant and cancer risk
    • COI: 1:CAS:528:DC%2BD2MXlvFSitbk%3D, PID: 15678496
    • Neuhausen SL, Slattery ML, Garner CP et al (2005) Prostate cancer risk and IRS1, IRS2, IGF1, and INS polymorphisms: Strong association of IRS1 G972R variant and cancer risk. Prostate 64(2):168–174
    • (2005) Prostate , vol.64 , Issue.2 , pp. 168-174
    • Neuhausen, S.L.1    Slattery, M.L.2    Garner, C.P.3
  • 170
    • 20944434462 scopus 로고    scopus 로고
    • IGF1 (CA)(19) repeat and IGFBP3-202A/C genotypes and the risk of prostate cancer in black and white men
    • COI: 1:CAS:528:DC%2BD2MXhs1GhsL8%3D
    • Schildkraut JM, Demark-Wahnefried W, Wenham RM et al (2005) IGF1 (CA)(19) repeat and IGFBP3-202A/C genotypes and the risk of prostate cancer in black and white men. Cancer Epidemiol Biomark Prev 14(2):403–408
    • (2005) Cancer Epidemiol Biomark Prev , vol.14 , Issue.2 , pp. 403-408
    • Schildkraut, J.M.1    Demark-Wahnefried, W.2    Wenham, R.M.3
  • 171
    • 31544474588 scopus 로고    scopus 로고
    • Common genetic variation in IGF1 and prostate cancer risk in the Multiethnic Cohort
    • COI: 1:CAS:528:DC%2BD28Xmsl2rsw%3D%3D, PID: 16418515
    • Cheng I, Stram DO, Penney KL et al (2006) Common genetic variation in IGF1 and prostate cancer risk in the Multiethnic Cohort. J Natl Cancer Inst 98(2):123–134
    • (2006) J Natl Cancer Inst , vol.98 , Issue.2 , pp. 123-134
    • Cheng, I.1    Stram, D.O.2    Penney, K.L.3
  • 172
    • 33750527523 scopus 로고    scopus 로고
    • Haplotype-based association studies of IGFBP1 and IGFBP3 with prostate and breast cancer risk: the multiethnic cohort
    • COI: 1:CAS:528:DC%2BD28XhtVGktbbN
    • Cheng I, Penney KL, Stram DO et al (2006) Haplotype-based association studies of IGFBP1 and IGFBP3 with prostate and breast cancer risk: the multiethnic cohort. Cancer Epidemiol Biomark Prev 15(10):1993–1997
    • (2006) Cancer Epidemiol Biomark Prev , vol.15 , Issue.10 , pp. 1993-1997
    • Cheng, I.1    Penney, K.L.2    Stram, D.O.3
  • 173
    • 36849026070 scopus 로고    scopus 로고
    • Implications for prostate cancer of insulin-like growth factor-I (IGF-I) genetic variation and circulating IGF-I levels
    • COI: 1:CAS:528:DC%2BD1cXmslWgsbw%3D, PID: 17911177
    • Johansson M, Mckay JD, Wiklund F et al (2007) Implications for prostate cancer of insulin-like growth factor-I (IGF-I) genetic variation and circulating IGF-I levels. J Clin Endocrinol Metab 92(12):4820–4826
    • (2007) J Clin Endocrinol Metab , vol.92 , Issue.12 , pp. 4820-4826
    • Johansson, M.1    Mckay, J.D.2    Wiklund, F.3
  • 174
    • 0036468136 scopus 로고    scopus 로고
    • Association of preoperative plasma levels of insulin-like growth factor I and insulin-like growth factor binding proteins-2 and – 3 with prostate cancer invasion, progression, and metastasis
    • COI: 1:CAS:528:DC%2BD38XhsVGmtL0%3D, PID: 11821468
    • Shariat SF, Lamb DJ, Kattan MW et al (2002) Association of preoperative plasma levels of insulin-like growth factor I and insulin-like growth factor binding proteins-2 and – 3 with prostate cancer invasion, progression, and metastasis. J Clin Oncol 20(3):833–841
    • (2002) J Clin Oncol , vol.20 , Issue.3 , pp. 833-841
    • Shariat, S.F.1    Lamb, D.J.2    Kattan, M.W.3
  • 175
    • 33745726110 scopus 로고    scopus 로고
    • Circulating insulin-like growth factor-I and binding protein-3 and risk of prostate cancer
    • COI: 1:CAS:528:DC%2BD28Xls1ehsbw%3D
    • Severi G, Morris HA, MacInnis RJ et al (2006) Circulating insulin-like growth factor-I and binding protein-3 and risk of prostate cancer. Cancer Epidemiol Biomark Prev 15(6):1137–1141
    • (2006) Cancer Epidemiol Biomark Prev , vol.15 , Issue.6 , pp. 1137-1141
    • Severi, G.1    Morris, H.A.2    MacInnis, R.J.3
  • 176
    • 0027326228 scopus 로고
    • Serum insulin-like growth factor-binding protein-2 (Igfbp-2) is increased and Igfbp-3 is decreased in patients with prostate-cancer - correlation with serum prostate-specific antigen
    • COI: 1:STN:280:DyaK3szhsFGqtg%3D%3D, PID: 7686915
    • Kanety H, Madjar Y, Dagan Y et al (1993) Serum insulin-like growth factor-binding protein-2 (Igfbp-2) is increased and Igfbp-3 is decreased in patients with prostate-cancer - correlation with serum prostate-specific antigen. J Clin Endocrinol Metab 77(1):229–233
    • (1993) J Clin Endocrinol Metab , vol.77 , Issue.1 , pp. 229-233
    • Kanety, H.1    Madjar, Y.2    Dagan, Y.3
  • 177
    • 0030896613 scopus 로고    scopus 로고
    • Insulin-like growth factor-binding protein-2 in patients with prostate carcinoma and benign prostatic hyperplasia
    • COI: 1:STN:280:DyaK2szgtFShtg%3D%3D
    • Ho PJ, Baxter RC (1997) Insulin-like growth factor-binding protein-2 in patients with prostate carcinoma and benign prostatic hyperplasia. Clin Endocrinol 46(3):333–342
    • (1997) Clin Endocrinol , vol.46 , Issue.3 , pp. 333-342
    • Ho, P.J.1    Baxter, R.C.2
  • 178
    • 0000820311 scopus 로고    scopus 로고
    • Serum insulin-like growth factor-1 is not a useful masker of prostate cancer
    • COI: 1:STN:280:DyaK1M3ps1Oqsw%3D%3D, PID: 10368242
    • Cutting CWM, Hunt C, Nisbet JA et al (1999) Serum insulin-like growth factor-1 is not a useful masker of prostate cancer. Bju Int 83(9):996–999
    • (1999) Bju Int , vol.83 , Issue.9 , pp. 996-999
    • Cutting, C.W.M.1    Hunt, C.2    Nisbet, J.A.3
  • 179
    • 0035701143 scopus 로고    scopus 로고
    • Prostatic fluid-free insulin-like growth factor-1 in relation to prostate cancer
    • COI: 1:CAS:528:DC%2BD38XivFSjtg%3D%3D, PID: 11851619
    • Perk H, Serel TA, Delibas N et al (2001) Prostatic fluid-free insulin-like growth factor-1 in relation to prostate cancer. Bju Int 88(9):946–949
    • (2001) Bju Int , vol.88 , Issue.9 , pp. 946-949
    • Perk, H.1    Serel, T.A.2    Delibas, N.3
  • 181
    • 16644395694 scopus 로고    scopus 로고
    • Vascular endothelium growth factor and insulin-like growth factors in prostatic cancer
    • Trapeznikova MF, Shibaeva AN, Ianshin A (2004) Vascular endothelium growth factor and insulin-like growth factors in prostatic cancer. Urologiya 1:17–21
    • (2004) Urologiya , vol.1 , pp. 17-21
    • Trapeznikova, M.F.1    Shibaeva, A.N.2    Ianshin, A.3
  • 182
    • 4243202854 scopus 로고    scopus 로고
    • Are plasma insulin-like growth factor I (IGF-I) and IGF-binding protein 3 (IGFBP-3) useful markers of prostate cancer?
    • COI: 1:CAS:528:DC%2BD2cXntlWhs7o%3D, PID: 15255551
    • Lopez JB, Sahabudin RM, Chin LP (2004) Are plasma insulin-like growth factor I (IGF-I) and IGF-binding protein 3 (IGFBP-3) useful markers of prostate cancer? Int J Biol Markers 19(2):164–167
    • (2004) Int J Biol Markers , vol.19 , Issue.2 , pp. 164-167
    • Lopez, J.B.1    Sahabudin, R.M.2    Chin, L.P.3
  • 183
    • 20444477134 scopus 로고    scopus 로고
    • Putative role of serum insulin-like growth factor-1 (IGF-1) and IGF binding protein-3 (IGFBP-3) levels in the development of prostate cancer in Arab men
    • COI: 1:CAS:528:DC%2BD2MXisVShsrk%3D, PID: 15775992
    • Kehinde EO, Akanji AO, Mojiminiyi OA et al (2005) Putative role of serum insulin-like growth factor-1 (IGF-1) and IGF binding protein-3 (IGFBP-3) levels in the development of prostate cancer in Arab men. Prostate Cancer Prostatic Dis 8(1):84–90
    • (2005) Prostate Cancer Prostatic Dis , vol.8 , Issue.1 , pp. 84-90
    • Kehinde, E.O.1    Akanji, A.O.2    Mojiminiyi, O.A.3
  • 184
    • 84886051687 scopus 로고    scopus 로고
    • Trait marker IGF1 is more diagnostic than PSA in Ca prostate, study at local population of Karachi
    • Iltaf M, Jagdesh, Panjwani JP et al (2013) Trait marker IGF1 is more diagnostic than PSA in Ca prostate, study at local population of Karachi. Pak J Med Health Sci 7:626–629
    • (2013) Pak J Med Health Sci , vol.7 , pp. 626-629
    • Iltaf, M.1    Jagdesh2    Panjwani, J.P.3
  • 185
    • 39449089183 scopus 로고    scopus 로고
    • Genetic polymorphisms in CYP17, CYP3A4, CYP19A1, SRD5A2, IGF-1, and IGFBP-3 and prostate cancer risk in African-American men: The flint men’s health study
    • COI: 1:CAS:528:DC%2BD1cXjtFemu74%3D, PID: 18163429
    • Sarma AV, Dunn RL, Lange LA et al (2008) Genetic polymorphisms in CYP17, CYP3A4, CYP19A1, SRD5A2, IGF-1, and IGFBP-3 and prostate cancer risk in African-American men: The flint men’s health study. Prostate 68(3):296–305
    • (2008) Prostate , vol.68 , Issue.3 , pp. 296-305
    • Sarma, A.V.1    Dunn, R.L.2    Lange, L.A.3
  • 186
    • 33645868681 scopus 로고    scopus 로고
    • Insulin-like growth factor (IGF) binding protein-3 attenuates prostate tumor growth by IGF-dependent and IGF-independent mechanisms
    • COI: 1:CAS:528:DC%2BD28XjvFOrtLc%3D, PID: 16469805
    • Silha JV, Sheppard PC, Mishra S et al (2006) Insulin-like growth factor (IGF) binding protein-3 attenuates prostate tumor growth by IGF-dependent and IGF-independent mechanisms. Endocrinology 147(5):2112–2121
    • (2006) Endocrinology , vol.147 , Issue.5 , pp. 2112-2121
    • Silha, J.V.1    Sheppard, P.C.2    Mishra, S.3
  • 187
    • 44849089393 scopus 로고    scopus 로고
    • Conditional deletion of insulin-like growth factor-I receptor in prostate epithelium
    • COI: 1:CAS:528:DC%2BD1cXltlSltL8%3D, PID: 18451178
    • Sutherland BW, Knoblaugh SE, Kaplan-Lefko PJ et al (2008) Conditional deletion of insulin-like growth factor-I receptor in prostate epithelium. Cancer Res 68(9):3495–3504
    • (2008) Cancer Res , vol.68 , Issue.9 , pp. 3495-3504
    • Sutherland, B.W.1    Knoblaugh, S.E.2    Kaplan-Lefko, P.J.3
  • 188
    • 44849114351 scopus 로고    scopus 로고
    • Targeted deletion of hepatic Igf1 in TRAMP mice leads to dramatic alterations in the circulating insulin-like growth factor axis but does not reduce tumor progression
    • COI: 1:CAS:528:DC%2BD1cXltlSlsLo%3D, PID: 18451161
    • Anzo M, Cobb LJ, Hwang DL et al (2008) Targeted deletion of hepatic Igf1 in TRAMP mice leads to dramatic alterations in the circulating insulin-like growth factor axis but does not reduce tumor progression. Cancer Res 68(9):3342–3349
    • (2008) Cancer Res , vol.68 , Issue.9 , pp. 3342-3349
    • Anzo, M.1    Cobb, L.J.2    Hwang, D.L.3
  • 189
    • 79960939160 scopus 로고    scopus 로고
    • IGFBP-3 is a metastasis suppression gene in prostate cancer
    • COI: 1:CAS:528:DC%2BC3MXpsVOhtbY%3D, PID: 21697285
    • Mehta HH, Gao QL, Galet C et al (2011) IGFBP-3 is a metastasis suppression gene in prostate cancer. Cancer Res 71(15):5154–5163
    • (2011) Cancer Res , vol.71 , Issue.15 , pp. 5154-5163
    • Mehta, H.H.1    Gao, Q.L.2    Galet, C.3
  • 190
    • 4344591505 scopus 로고    scopus 로고
    • Growth inhibition of human prostate cancer cells in human adult bone implanted into nonobese diabetic/severe combined immunodeficient mice by a ligand-specific antibody to human insulin-like growth factors
    • COI: 1:CAS:528:DC%2BD2cXntFCltrg%3D, PID: 15342412
    • Goya M, Miyamoto S, Nagai K et al (2004) Growth inhibition of human prostate cancer cells in human adult bone implanted into nonobese diabetic/severe combined immunodeficient mice by a ligand-specific antibody to human insulin-like growth factors. Cancer Res 64(17):6252–6258
    • (2004) Cancer Res , vol.64 , Issue.17 , pp. 6252-6258
    • Goya, M.1    Miyamoto, S.2    Nagai, K.3
  • 191
    • 17144416483 scopus 로고    scopus 로고
    • In vivo effects of the human type I insulin-like growth factor receptor antibody A12 on androgen-dependent and androgen-independent xenograft human prostate tumors
    • COI: 1:CAS:528:DC%2BD2MXjtlejtb0%3D, PID: 15837762
    • Wu JD, Odman A, Higgins LM et al (2005) In vivo effects of the human type I insulin-like growth factor receptor antibody A12 on androgen-dependent and androgen-independent xenograft human prostate tumors. Clin Cancer Res 11(8):3065–3074
    • (2005) Clin Cancer Res , vol.11 , Issue.8 , pp. 3065-3074
    • Wu, J.D.1    Odman, A.2    Higgins, L.M.3
  • 192
    • 77956939368 scopus 로고    scopus 로고
    • Identification of a novel cell death receptor mediating IGFBP-3-induced anti-tumor effects in breast and prostate cancer
    • COI: 1:CAS:528:DC%2BC3cXhtFKksL3I, PID: 20353938
    • Ingermann AR, Yang YF, Han JF et al (2010) Identification of a novel cell death receptor mediating IGFBP-3-induced anti-tumor effects in breast and prostate cancer. J Biol Chem 285(39):30233–30246
    • (2010) J Biol Chem , vol.285 , Issue.39 , pp. 30233-30246
    • Ingermann, A.R.1    Yang, Y.F.2    Han, J.F.3
  • 193
    • 74949144325 scopus 로고    scopus 로고
    • Targeting of bone-derived insulin-like growth factor-ii by a human neutralizing antibody suppresses the growth of prostate cancer cells in a human bone environment
    • COI: 1:CAS:528:DC%2BC3cXotFym, PID: 20028742
    • Kimura T, Kuwata T, Ashimine S et al (2010) Targeting of bone-derived insulin-like growth factor-ii by a human neutralizing antibody suppresses the growth of prostate cancer cells in a human bone environment. Clin Cancer Res 16(1):121–129
    • (2010) Clin Cancer Res , vol.16 , Issue.1 , pp. 121-129
    • Kimura, T.1    Kuwata, T.2    Ashimine, S.3
  • 194
    • 12944335316 scopus 로고    scopus 로고
    • Deregulated expression of insulin-like growth factor 1 in prostate epithelium leads to neoplasia in transgenic mice
    • COI: 1:CAS:528:DC%2BD3cXitlWqt7Y%3D, PID: 10737798
    • DiGiovanni J, Kiguchi K, Frijhoff A et al (2000) Deregulated expression of insulin-like growth factor 1 in prostate epithelium leads to neoplasia in transgenic mice. Proc Natl Acad Sci USA 97(7):3455–3460
    • (2000) Proc Natl Acad Sci USA , vol.97 , Issue.7 , pp. 3455-3460
    • DiGiovanni, J.1    Kiguchi, K.2    Frijhoff, A.3
  • 195
    • 85017881048 scopus 로고    scopus 로고
    • Aging-related loss of insulin-like growth factor-2 (Igf2) imprinting in the prostate
    • Fu VX, Dobosy JR, Dosetelle JA et al (2008) Aging-related loss of insulin-like growth factor-2 (Igf2) imprinting in the prostate. J Urol 179(4):394–394
    • (2008) J Urol , vol.179 , Issue.4 , pp. 394
    • Fu, V.X.1    Dobosy, J.R.2    Dosetelle, J.A.3
  • 196
    • 79952090081 scopus 로고    scopus 로고
    • Milk and linear growth: programming of the IGF-I axis and implication for health in adulthood
    • COI: 1:CAS:528:DC%2BC3MXhtV2qsrjK
    • Martin RM, Holly JMP, Gunnell D (2011) Milk and linear growth: programming of the IGF-I axis and implication for health in adulthood. Milk Milk Prod Hum Nutr 67:79–97
    • (2011) Milk Milk Prod Hum Nutr , vol.67 , pp. 79-97
    • Martin, R.M.1    Holly, J.M.P.2    Gunnell, D.3
  • 197
    • 84871848283 scopus 로고    scopus 로고
    • Evaluation of excess statistical significance in meta-analyses of 98 biomarker associations with cancer risk
    • COI: 1:CAS:528:DC%2BC38XhvFSitbfP, PID: 23090067
    • Tsilidis KK, Papatheodorou SI, Evangelou E et al (2012) Evaluation of excess statistical significance in meta-analyses of 98 biomarker associations with cancer risk. J Natl Cancer Inst 104(24):1867–1878
    • (2012) J Natl Cancer Inst , vol.104 , Issue.24 , pp. 1867-1878
    • Tsilidis, K.K.1    Papatheodorou, S.I.2    Evangelou, E.3
  • 198
    • 84922537956 scopus 로고    scopus 로고
    • Analysis of IGF(CA)19 and IGFBP3-202A/C gene polymorphisms in patients with acromegaly: association with clinical presentation and response to treatments
    • COI: 1:CAS:528:DC%2BC2MXksFehurw%3D, PID: 25385818
    • Ramos-Levi AM, Marazuela M, Paniagua A et al (2015) Analysis of IGF(CA)19 and IGFBP3-202A/C gene polymorphisms in patients with acromegaly: association with clinical presentation and response to treatments. Eur J Endocrinol 172(2):115–122
    • (2015) Eur J Endocrinol , vol.172 , Issue.2 , pp. 115-122
    • Ramos-Levi, A.M.1    Marazuela, M.2    Paniagua, A.3
  • 199
    • 84978264652 scopus 로고    scopus 로고
    • Assessing the role of insulin-like growth factors and binding proteins in prostate cancer using Mendelian randomization: genetic variants as instruments for circulating levels
    • COI: 1:CAS:528:DC%2BC28XhtVCis7zI, PID: 27225428
    • Bonilla C, Lewis SJ, Rowlands MA et al (2016) Assessing the role of insulin-like growth factors and binding proteins in prostate cancer using Mendelian randomization: genetic variants as instruments for circulating levels. Int J Cancer 139(7):1520–1533
    • (2016) Int J Cancer , vol.139 , Issue.7 , pp. 1520-1533
    • Bonilla, C.1    Lewis, S.J.2    Rowlands, M.A.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.