메뉴 건너뛰기




Volumn 198, Issue 7, 2017, Pages 2760-2771

Peripherally generated Foxp3+ regulatory T cells mediate the immunomodulatory effects of IVIg in allergic airways disease

Author keywords

[No Author keywords available]

Indexed keywords

IMMUNOGLOBULIN; OVALBUMIN; TRANSCRIPTION FACTOR FOXP3; FORKHEAD TRANSCRIPTION FACTOR; FOXP3 PROTEIN, MOUSE; TRANSCRIPTOME;

EID: 85016287762     PISSN: 00221767     EISSN: 15506606     Source Type: Journal    
DOI: 10.4049/jimmunol.1502361     Document Type: Article
Times cited : (14)

References (61)
  • 1
    • 0035180065 scopus 로고    scopus 로고
    • Immunologic tolerance maintained by CD25+ CD4+ regulatory T cells: Their common role in controlling autoimmunity, tumor immunity, and transplantation tolerance
    • Sakaguchi, S., N. Sakaguchi, J. Shimizu, S. Yamazaki, T. Sakihama, M. Itoh, Y. Kuniyasu, T. Nomura, M. Toda, and T. Takahashi. 2001. Immunologic tolerance maintained by CD25+ CD4+ regulatory T cells: their common role in controlling autoimmunity, tumor immunity, and transplantation tolerance. Immunol. Rev. 182: 18-32.
    • (2001) Immunol. Rev. , vol.182 , pp. 18-32
    • Sakaguchi, S.1    Sakaguchi, N.2    Shimizu, J.3    Yamazaki, S.4    Sakihama, T.5    Itoh, M.6    Kuniyasu, Y.7    Nomura, T.8    Toda, M.9    Takahashi, T.10
  • 2
    • 0347785480 scopus 로고    scopus 로고
    • Control of regulatory T cell development by the transcription factor Foxp3
    • Hori, S., T. Nomura, and S. Sakaguchi. 2003. Control of regulatory T cell development by the transcription factor Foxp3. Science 299: 1057-1061.
    • (2003) Science , vol.299 , pp. 1057-1061
    • Hori, S.1    Nomura, T.2    Sakaguchi, S.3
  • 4
    • 84864080545 scopus 로고    scopus 로고
    • The immunogenetics of immune dysregulation, polyendocrinopathy, enteropathy, X linked (IPEX) syndrome. [Published erratum appears in 2012 J. Med. Genet. 49: 784.]
    • d'Hennezel, E., K. Bin Dhuban, T. Torgerson, and C. A. Piccirillo. 2012. The immunogenetics of immune dysregulation, polyendocrinopathy, enteropathy, X linked (IPEX) syndrome. [Published erratum appears in 2012 J. Med. Genet. 49: 784.] J. Med. Genet. 49: 291-302.
    • (2012) J. Med. Genet. , vol.49 , pp. 291-302
    • D'Hennezel, E.1    Bin Dhuban, K.2    Torgerson, T.3    Piccirillo, C.A.4
  • 6
    • 84875469030 scopus 로고    scopus 로고
    • Antigen-specific memory regulatory CD4+Foxp3+ T cells control memory responses to influenza virus infection
    • Brincks, E. L., A. D. Roberts, T. Cookenham, S. Sell, J. E. Kohlmeier, M. A. Blackman, and D. L. Woodland. 2013. Antigen-specific memory regulatory CD4+Foxp3+ T cells control memory responses to influenza virus infection. J. Immunol. 190: 3438-3446.
    • (2013) J. Immunol. , vol.190 , pp. 3438-3446
    • Brincks, E.L.1    Roberts, A.D.2    Cookenham, T.3    Sell, S.4    Kohlmeier, J.E.5    Blackman, M.A.6    Woodland, D.L.7
  • 7
    • 84864968916 scopus 로고    scopus 로고
    • Low frequency of CD8+CD25+FOXP3BRIGHT T cells and FOXP3 mRNA expression in the peripheral blood of allergic asthma patients
    • Eusebio, M., L. Kraszula, M. Kupczyk, P. Kuna, and M. Pietruczuk. 2012. Low frequency of CD8+CD25+FOXP3BRIGHT T cells and FOXP3 mRNA expression in the peripheral blood of allergic asthma patients. J. Biol. Regul. Homeost. Agents 26: 211-220.
    • (2012) J. Biol. Regul. Homeost. Agents , vol.26 , pp. 211-220
    • Eusebio, M.1    Kraszula, L.2    Kupczyk, M.3    Kuna, P.4    Pietruczuk, M.5
  • 10
    • 77957843236 scopus 로고    scopus 로고
    • Increased airway T regulatory cells in asthmatic subjects
    • Smyth, L. J., A. Eustace, U. Kolsum, J. Blaikely, and D. Singh. 2010. Increased airway T regulatory cells in asthmatic subjects. Chest 138: 905-912.
    • (2010) Chest , vol.138 , pp. 905-912
    • Smyth, L.J.1    Eustace, A.2    Kolsum, U.3    Blaikely, J.4    Singh, D.5
  • 11
    • 78349262332 scopus 로고    scopus 로고
    • Role of T regulatory cells in the pathogenesis of asthma
    • author reply 1283
    • Yang, Y., H. L. Zhang, and J. Wu. 2010. Role of T regulatory cells in the pathogenesis of asthma. Chest 138: 1282-1283, author reply 1283.
    • (2010) Chest , vol.138 , pp. 1282-1283
    • Yang, Y.1    Zhang, H.L.2    Wu, J.3
  • 12
    • 84949550615 scopus 로고    scopus 로고
    • Induction of regulatory T cells by intravenous immunoglobulin: A bridge between adaptive and innate immunity
    • Kaufman, G. N., A. H. Massoud, M. Dembele, M. Yona, C. A. Piccirillo, and B. D. Mazer. 2015. Induction of regulatory T cells by intravenous immunoglobulin: a bridge between adaptive and innate immunity. Front. Immunol. 6: 469.
    • (2015) Front. Immunol. , vol.6 , pp. 469
    • Kaufman, G.N.1    Massoud, A.H.2    Dembele, M.3    Yona, M.4    Piccirillo, C.A.5    Mazer, B.D.6
  • 13
    • 84863628102 scopus 로고    scopus 로고
    • Adoptive transfer of induced-Treg cells effectively attenuates murine airway allergic inflammation
    • Xu, W., Q. Lan, M. Chen, H. Chen, N. Zhu, X. Zhou, J. Wang, H. Fan, C. S. Yan, J. L. Kuang, et al. 2012. Adoptive transfer of induced-Treg cells effectively attenuates murine airway allergic inflammation. PLoS One 7: e40314.
    • (2012) PLoS One , vol.7 , pp. e40314
    • Xu, W.1    Lan, Q.2    Chen, M.3    Chen, H.4    Zhu, N.5    Zhou, X.6    Wang, J.7    Fan, H.8    Yan, C.S.9    Kuang, J.L.10
  • 16
    • 84886806068 scopus 로고    scopus 로고
    • Intravenous immunoglobulin expands regulatory T cells via induction of cyclooxygenase-2-dependent prostaglandin E2 in human dendritic cells
    • Trinath, J., P. Hegde, M. Sharma, M. S. Maddur, M. Rabin, J. M. Vallat, L. Magy, K. N. Balaji, S. V. Kaveri, and J. Bayry. 2013. Intravenous immunoglobulin expands regulatory T cells via induction of cyclooxygenase-2-dependent prostaglandin E2 in human dendritic cells. Blood 122: 1419-1427.
    • (2013) Blood , vol.122 , pp. 1419-1427
    • Trinath, J.1    Hegde, P.2    Sharma, M.3    Maddur, M.S.4    Rabin, M.5    Vallat, J.M.6    Magy, L.7    Balaji, K.N.8    Kaveri, S.V.9    Bayry, J.10
  • 18
    • 33846485153 scopus 로고    scopus 로고
    • Regulatory T cells prevent catastrophic autoimmunity throughout the lifespan of mice
    • Kim, J. M., J. P. Rasmussen, and A. Y. Rudensky. 2007. Regulatory T cells prevent catastrophic autoimmunity throughout the lifespan of mice. Nat. Immunol. 8: 191-197.
    • (2007) Nat. Immunol. , vol.8 , pp. 191-197
    • Kim, J.M.1    Rasmussen, J.P.2    Rudensky, A.Y.3
  • 19
    • 0031897801 scopus 로고    scopus 로고
    • Defective TCR expression in transgenic mice constructed using cDNA-based a- and b-chain genes under the control of heterologous regulatory elements
    • Barnden, M. J., J. Allison, W. R. Heath, and F. R. Carbone. 1998. Defective TCR expression in transgenic mice constructed using cDNA-based a- and b-chain genes under the control of heterologous regulatory elements. Immunol. Cell Biol. 76: 34-40.
    • (1998) Immunol. Cell Biol. , vol.76 , pp. 34-40
    • Barnden, M.J.1    Allison, J.2    Heath, W.R.3    Carbone, F.R.4
  • 20
    • 33847370194 scopus 로고    scopus 로고
    • Regulatory T cells dynamically control the primary immune response to foreign antigen
    • Haribhai, D., W. Lin, L. M. Relland, N. Truong, C. B. Williams, and T. A. Chatila. 2007. Regulatory T cells dynamically control the primary immune response to foreign antigen. J. Immunol. 178: 2961-2972.
    • (2007) J. Immunol. , vol.178 , pp. 2961-2972
    • Haribhai, D.1    Lin, W.2    Relland, L.M.3    Truong, N.4    Williams, C.B.5    Chatila, T.A.6
  • 22
    • 79955682501 scopus 로고    scopus 로고
    • Analysis of human FOXP3+ Treg cells phenotype and function
    • d'Hennezel, E., and C. A. Piccirillo. 2011. Analysis of human FOXP3+ Treg cells phenotype and function. Methods Mol. Biol. 707: 199-218.
    • (2011) Methods Mol. Biol. , vol.707 , pp. 199-218
    • D'Hennezel, E.1    Piccirillo, C.A.2
  • 23
    • 79959560094 scopus 로고    scopus 로고
    • Single-cell analysis of the human T regulatory population uncovers functional heterogeneity and instability within FOXP3+ cells
    • d'Hennezel, E., E. Yurchenko, E. Sgouroudis, V. Hay, and C. A. Piccirillo. 2011. Single-cell analysis of the human T regulatory population uncovers functional heterogeneity and instability within FOXP3+ cells. J. Immunol. 186: 6788-6797.
    • (2011) J. Immunol. , vol.186 , pp. 6788-6797
    • D'Hennezel, E.1    Yurchenko, E.2    Sgouroudis, E.3    Hay, V.4    Piccirillo, C.A.5
  • 24
    • 77957230671 scopus 로고    scopus 로고
    • A framework for oligonucleotide microarray preprocessing
    • Carvalho, B. S., and R. A. Irizarry. 2010. A framework for oligonucleotide microarray preprocessing. Bioinformatics 26: 2363-2367.
    • (2010) Bioinformatics , vol.26 , pp. 2363-2367
    • Carvalho, B.S.1    Irizarry, R.A.2
  • 25
    • 84926507971 scopus 로고    scopus 로고
    • Limma powers differential expression analyses for RNA-sequencing and microarray studies
    • Ritchie, M. E., B. Phipson, D. Wu, Y. Hu, C. W. Law, W. Shi, and G. K. Smyth. 2015. limma powers differential expression analyses for RNA-sequencing and microarray studies. Nucleic Acids Res. 43: e47.
    • (2015) Nucleic Acids Res. , vol.43 , pp. e47
    • Ritchie, M.E.1    Phipson, B.2    Wu, D.3    Hu, Y.4    Law, C.W.5    Shi, W.6    Smyth, G.K.7
  • 27
    • 4544341015 scopus 로고    scopus 로고
    • Linear models and empirical bayes methods for assessing differential expression in microarray experiments
    • Article3
    • Smyth, G. K. 2004. Linear models and empirical bayes methods for assessing differential expression in microarray experiments. Stat. Appl. Genet. Mol. Biol. 3: Article3.
    • (2004) Stat. Appl. Genet. Mol. Biol. , vol.3
    • Smyth, G.K.1
  • 28
    • 0035710746 scopus 로고    scopus 로고
    • Analysis of relative gene expression data using real-time quantitative PCR and the 22DDC(T) method
    • Livak, K. J., and T. D. Schmittgen. 2001. Analysis of relative gene expression data using real-time quantitative PCR and the 22DDC(T) method. Methods 25: 402-408.
    • (2001) Methods , vol.25 , pp. 402-408
    • Livak, K.J.1    Schmittgen, T.D.2
  • 31
    • 84892511644 scopus 로고    scopus 로고
    • Large-scale gene function analysis with the PANTHER classification system
    • Mi, H., A. Muruganujan, J. T. Casagrande, and P. D. Thomas. 2013. Large-scale gene function analysis with the PANTHER classification system. Nat. Protoc. 8: 1551-1566.
    • (2013) Nat. Protoc. , vol.8 , pp. 1551-1566
    • Mi, H.1    Muruganujan, A.2    Casagrande, J.T.3    Thomas, P.D.4
  • 32
    • 61449172037 scopus 로고    scopus 로고
    • Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources
    • Huang da, W., B. T. Sherman, and R. A. Lempicki. 2009. Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources. Nat. Protoc. 4: 44-57.
    • (2009) Nat. Protoc. , vol.4 , pp. 44-57
    • Huang da, W.1    Sherman, B.T.2    Lempicki, R.A.3
  • 33
    • 47249119632 scopus 로고    scopus 로고
    • Latency-associated peptide identifies a novel CD4+CD25+ regulatory T cell subset with TGFb-mediated function and enhanced suppression of experimental autoimmune encephalomyelitis
    • Chen, M. L., B. S. Yan, Y. Bando, V. K. Kuchroo, and H. L. Weiner. 2008. Latency-associated peptide identifies a novel CD4+CD25+ regulatory T cell subset with TGFb-mediated function and enhanced suppression of experimental autoimmune encephalomyelitis. J. Immunol. 180: 7327-7337.
    • (2008) J. Immunol. , vol.180 , pp. 7327-7337
    • Chen, M.L.1    Yan, B.S.2    Bando, Y.3    Kuchroo, V.K.4    Weiner, H.L.5
  • 35
    • 84871402588 scopus 로고    scopus 로고
    • Functional crosstalk between dendritic cells and Foxp3+ regulatory T cells in the maintenance of immune tolerance
    • Kornete, M., and C. A. Piccirillo. 2012. Functional crosstalk between dendritic cells and Foxp3+ regulatory T cells in the maintenance of immune tolerance. Front. Immunol. 3: 165.
    • (2012) Front. Immunol. , vol.3 , pp. 165
    • Kornete, M.1    Piccirillo, C.A.2
  • 36
    • 84883754405 scopus 로고    scopus 로고
    • Generation and function of induced regulatory T cells
    • Schmitt, E. G., and C. B. Williams. 2013. Generation and function of induced regulatory T cells. Front. Immunol. 4: 152.
    • (2013) Front. Immunol. , vol.4 , pp. 152
    • Schmitt, E.G.1    Williams, C.B.2
  • 37
    • 84883746315 scopus 로고    scopus 로고
    • The role of regulatory T cells in the biology of graft versus host disease
    • Beres, A. J., and W. R. Drobyski. 2013. The role of regulatory T cells in the biology of graft versus host disease. Front. Immunol. 4: 163.
    • (2013) Front. Immunol. , vol.4 , pp. 163
    • Beres, A.J.1    Drobyski, W.R.2
  • 38
    • 0348223787 scopus 로고    scopus 로고
    • Conversion of peripheral CD4+CD252 naive T cells to CD4+ CD25+ regulatory T cells by TGF-b induction of transcription factor Foxp3
    • Chen, W., W. Jin, N. Hardegen, K. J. Lei, L. Li, N. Marinos, G. McGrady, and S. M. Wahl. 2003. Conversion of peripheral CD4+CD252 naive T cells to CD4+ CD25+ regulatory T cells by TGF-b induction of transcription factor Foxp3. J. Exp. Med. 198: 1875-1886.
    • (2003) J. Exp. Med. , vol.198 , pp. 1875-1886
    • Chen, W.1    Jin, W.2    Hardegen, N.3    Lei, K.J.4    Li, L.5    Marinos, N.6    McGrady, G.7    Wahl, S.M.8
  • 39
    • 80051935235 scopus 로고    scopus 로고
    • Antigen-specific TGF-b-induced regulatory T cells secrete chemokines, regulate T cell trafficking, and suppress ongoing autoimmunity
    • Nguyen, T. L., N. L. Sullivan, M. Ebel, R. M. Teague, and R. J. DiPaolo. 2011. Antigen-specific TGF-b-induced regulatory T cells secrete chemokines, regulate T cell trafficking, and suppress ongoing autoimmunity. J. Immunol. 187: 1745-1753.
    • (2011) J. Immunol. , vol.187 , pp. 1745-1753
    • Nguyen, T.L.1    Sullivan, N.L.2    Ebel, M.3    Teague, R.M.4    DiPaolo, R.J.5
  • 40
    • 83755173097 scopus 로고    scopus 로고
    • Inducible CD4+ LAP+Foxp32 regulatory T cells suppress allergic inflammation
    • Duan, W., T. So, A. K. Mehta, H. Choi, and M. Croft. 2011. Inducible CD4+ LAP+Foxp32 regulatory T cells suppress allergic inflammation. J. Immunol. 187: 6499-6507.
    • (2011) J. Immunol. , vol.187 , pp. 6499-6507
    • Duan, W.1    So, T.2    Mehta, A.K.3    Choi, H.4    Croft, M.5
  • 41
    • 84865712860 scopus 로고    scopus 로고
    • Identification of human regulatory T cells in the setting of T-cell activation and anti-CTLA-4 immunotherapy on the basis of expression of latency-associated peptide
    • Sun, J., D. N. Tang, T. Fu, and P. Sharma. 2012. Identification of human regulatory T cells in the setting of T-cell activation and anti-CTLA-4 immunotherapy on the basis of expression of latency-associated peptide. Cancer Discov. 2: 122-130.
    • (2012) Cancer Discov. , vol.2 , pp. 122-130
    • Sun, J.1    Tang, D.N.2    Fu, T.3    Sharma, P.4
  • 43
    • 80052287274 scopus 로고    scopus 로고
    • Helios expression is a marker of T cell activation and proliferation
    • Akimova, T., U. H. Beier, L. Wang, M. H. Levine, and W. W. Hancock. 2011. Helios expression is a marker of T cell activation and proliferation. PLoS One 6: e24226.
    • (2011) PLoS One , vol.6 , pp. e24226
    • Akimova, T.1    Beier, U.H.2    Wang, L.3    Levine, M.H.4    Hancock, W.W.5
  • 44
    • 84897944747 scopus 로고    scopus 로고
    • Lineage stability and phenotypic plasticity of Foxp3+ regulatory T cells
    • Hori, S. 2014. Lineage stability and phenotypic plasticity of Foxp3+ regulatory T cells. Immunol. Rev. 259: 159-172.
    • (2014) Immunol. Rev. , vol.259 , pp. 159-172
    • Hori, S.1
  • 45
    • 80053601510 scopus 로고    scopus 로고
    • Histone/ protein deacetylases control Foxp3 expression and the heat shock response of Tregulatory cells
    • Beier, U. H., T. Akimova, Y. Liu, L. Wang, and W. W. Hancock. 2011. Histone/ protein deacetylases control Foxp3 expression and the heat shock response of Tregulatory cells. Curr. Opin. Immunol. 23: 670-678.
    • (2011) Curr. Opin. Immunol. , vol.23 , pp. 670-678
    • Beier, U.H.1    Akimova, T.2    Liu, Y.3    Wang, L.4    Hancock, W.W.5
  • 47
    • 84897948864 scopus 로고    scopus 로고
    • Functional dynamics of Foxp3+ regulatory T cells in mice and humans
    • Bin Dhuban, K., M. Kornete, E. S Mason, and C. A. Piccirillo. 2014. Functional dynamics of Foxp3+ regulatory T cells in mice and humans. Immunol. Rev. 259: 140-158.
    • (2014) Immunol. Rev. , vol.259 , pp. 140-158
    • Bin Dhuban, K.1    Kornete, M.2    Mason, E.S.3    Piccirillo, C.A.4
  • 48
    • 84928807645 scopus 로고    scopus 로고
    • Granzyme A is required for regulatory T-cell mediated prevention of gastrointestinal graft-versus-host disease
    • Velaga, S., S. N. Ukena, U. Dringenberg, C. Alter, J. Pardo, O. Kershaw, and A. Franzke. 2015. Granzyme A is required for regulatory T-cell mediated prevention of gastrointestinal graft-versus-host disease. PLoS One 10: e0124927.
    • (2015) PLoS One , vol.10 , pp. e0124927
    • Velaga, S.1    Ukena, S.N.2    Dringenberg, U.3    Alter, C.4    Pardo, J.5    Kershaw, O.6    Franzke, A.7
  • 50
    • 33746442838 scopus 로고    scopus 로고
    • Vasoactive intestinal peptide: The dendritic cell → regulatory T cell axis
    • Delgado, M., E. Gonzalez-Rey, and D. Ganea. 2006. Vasoactive intestinal peptide: the dendritic cell → regulatory T cell axis. Ann. N. Y. Acad. Sci. 1070: 233-238.
    • (2006) Ann. N. Y. Acad. Sci. , vol.1070 , pp. 233-238
    • Delgado, M.1    Gonzalez-Rey, E.2    Ganea, D.3
  • 51
    • 84855472967 scopus 로고    scopus 로고
    • Dendritic cells induce antigen-specific regulatory T cells that prevent graft versus host disease and persist in mice
    • Sela, U., P. Olds, A. Park, S. J. Schlesinger, and R. M. Steinman. 2011. Dendritic cells induce antigen-specific regulatory T cells that prevent graft versus host disease and persist in mice. J. Exp. Med. 208: 2489-2496.
    • (2011) J. Exp. Med. , vol.208 , pp. 2489-2496
    • Sela, U.1    Olds, P.2    Park, A.3    Schlesinger, S.J.4    Steinman, R.M.5
  • 53
    • 38349191376 scopus 로고    scopus 로고
    • Expansion of CD4+CD25+ regulatory T cells by intravenous immunoglobulin: A critical factor in controlling experimental autoimmune encephalomyelitis
    • Ephrem, A., S. Chamat, C. Miquel, S. Fisson, L. Mouthon, G. Caligiuri, S. Delignat, S. Elluru, J. Bayry, S. Lacroix-Desmazes, et al. 2008. Expansion of CD4+CD25+ regulatory T cells by intravenous immunoglobulin: a critical factor in controlling experimental autoimmune encephalomyelitis. Blood 111: 715-722.
    • (2008) Blood , vol.111 , pp. 715-722
    • Ephrem, A.1    Chamat, S.2    Miquel, C.3    Fisson, S.4    Mouthon, L.5    Caligiuri, G.6    Delignat, S.7    Elluru, S.8    Bayry, J.9    Lacroix-Desmazes, S.10
  • 55
    • 84860751767 scopus 로고    scopus 로고
    • High-dose intravenous immunoglobulin treatment increases regulatory T cells in patients with eosinophilic granulomatosis with polyangiitis
    • Tsurikisawa, N., H. Saito, C. Oshikata, T. Tsuburai, and K. Akiyama. 2012. High-dose intravenous immunoglobulin treatment increases regulatory T cells in patients with eosinophilic granulomatosis with polyangiitis. J. Rheumatol. 39: 1019-1025.
    • (2012) J. Rheumatol. , vol.39 , pp. 1019-1025
    • Tsurikisawa, N.1    Saito, H.2    Oshikata, C.3    Tsuburai, T.4    Akiyama, K.5
  • 56
    • 84866177904 scopus 로고    scopus 로고
    • Thymic retention of CD4+CD25+ FoxP3+ T regulatory cells is associated with their peripheral deficiency and thrombocytopenia in a murine model of immune thrombocytopenia
    • Aslam, R., Y. Hu, S. Gebremeskel, G. B. Segel, E. R. Speck, L. Guo, M. Kim, H. Ni, J. Freedman, and J. W. Semple. 2012. Thymic retention of CD4+CD25+ FoxP3+ T regulatory cells is associated with their peripheral deficiency and thrombocytopenia in a murine model of immune thrombocytopenia. Blood 120: 2127-2132.
    • (2012) Blood , vol.120 , pp. 2127-2132
    • Aslam, R.1    Hu, Y.2    Gebremeskel, S.3    Segel, G.B.4    Speck, E.R.5    Guo, L.6    Kim, M.7    Ni, H.8    Freedman, J.9    Semple, J.W.10
  • 59
    • 50949084357 scopus 로고    scopus 로고
    • Advances in therapeutic immunomodulation of IgEmediated respiratory disease
    • 193-195
    • Settipane, R. A. 2008. Advances in therapeutic immunomodulation of IgEmediated respiratory disease. Med. Health R I 91: 187-190, 193-195.
    • (2008) Med. Health R i , vol.91 , pp. 187-190
    • Settipane, R.A.1
  • 60
    • 79961127439 scopus 로고    scopus 로고
    • Can anti-IgE therapy prevent airway remodeling in allergic asthma?
    • Rabe, K. F., W. J. Calhoun, N. Smith, and P. Jimenez. 2011. Can anti-IgE therapy prevent airway remodeling in allergic asthma? Allergy 66: 1142-1151.
    • (2011) Allergy , vol.66 , pp. 1142-1151
    • Rabe, K.F.1    Calhoun, W.J.2    Smith, N.3    Jimenez, P.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.