Macrophage-Derived mir-155-Containing Exosomes Suppress Fibroblast Proliferation and Promote Fibroblast Inflammation during Cardiac Injury

Molecular Therapy

Volumn 25, Issue 1, 2017, Pages 192-204

  Wang, Chunxiao ^a,b,c   Zhang, Congcong ^a,b,c   Liu, Luxin ^a,b,c   Xi, A ^a,b,c   Chen, Boya ^a,b,c   Li, Yulin ^a,b,c   Du, Jie ^a,b,c  

^a CAPITAL MEDICAL UNIVERSITY   (China)

^b BEIJING UNIVERSITY OF POSTS AND TELECOMMUNICATIONS   (China)

^c BEIJING INSTITUTE OF HEART   (China)

Author keywords

cardiac fibroblast; inflammation; mir 155; myocardial infarction; proliferation

Indexed keywords

ANTAGOMIR; COLLAGEN; MICRORNA 155; SUPPRESSOR OF CYTOKINE SIGNALING 1; MICRORNA; MIRN155 MICRORNA, MOUSE; SOS PROTEIN;

ACUTE HEART INFARCTION; ADULT; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL PROLIFERATION; CONTROLLED STUDY; DISEASE EXACERBATION; DOWN REGULATION; EXOSOME; FIBROBLAST; GENE EXPRESSION; GENE FUNCTION; HEART FUNCTION; HEART RUPTURE; IN VIVO STUDY; MACROPHAGE; MALE; MOUSE; NONHUMAN; PROTEIN EXPRESSION; UPREGULATION; ANIMAL; BIOLOGICAL MODEL; CARDIAC MUSCLE; CELL COMMUNICATION; DISEASE MODEL; GENE EXPRESSION REGULATION; GENETICS; HEART INFARCTION; INFLAMMATION; MACROPHAGE ACTIVATION; METABOLISM; MORTALITY; PATHOLOGY; RNA INTERFERENCE; RNA TRANSPORT;

ANIMALS; CELL COMMUNICATION; CELL PROLIFERATION; DISEASE MODELS, ANIMAL; EXOSOMES; FIBROBLASTS; GENE EXPRESSION; GENE EXPRESSION REGULATION; HEART RUPTURE, POST-INFARCTION; INFLAMMATION; MACROPHAGE ACTIVATION; MACROPHAGES; MICE; MICRORNAS; MODELS, BIOLOGICAL; MYOCARDIAL INFARCTION; MYOCARDIUM; RNA INTERFERENCE; RNA TRANSPORT; SOS1 PROTEIN;

EID: 85016270589     PISSN: 15250016     EISSN: 15250024     Source Type: Journal    
DOI: 10.1016/j.ymthe.2016.09.001     Document Type: Article

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