메뉴 건너뛰기




Volumn 23, Issue 6, 2017, Pages 1388-1396

Ipilimumab with stereotactic ablative radiation therapy: Phase i results and immunologic correlates from peripheral T cells

Author keywords

[No Author keywords available]

Indexed keywords

ALANINE AMINOTRANSFERASE; ASPARTATE AMINOTRANSFERASE; BILIRUBIN; CD3 ANTIGEN; CD4 ANTIGEN; CD8 ANTIGEN; IPILIMUMAB; TRANSCRIPTION FACTOR FOXP3; TUMOR MARKER;

EID: 85016147574     PISSN: 10780432     EISSN: 15573265     Source Type: Journal    
DOI: 10.1158/1078-0432.CCR-16-1432     Document Type: Article
Times cited : (266)

References (33)
  • 1
  • 3
    • 84926525215 scopus 로고    scopus 로고
    • Radiation and dual checkpoint blockade activate non-redundant immune mechanisms in cancer
    • Twyman-Saint Victor C, Rech AJ, Maity A, Rengan R, Pauken KE, Stelekati E, et al. Radiation and dual checkpoint blockade activate non-redundant immune mechanisms in cancer. Nature 2015;520:373-7.
    • (2015) Nature , vol.520 , pp. 373-377
    • Twyman-Saint Victor, C.1    Rech, A.J.2    Maity, A.3    Rengan, R.4    Pauken, K.E.5    Stelekati, E.6
  • 4
    • 33646704729 scopus 로고    scopus 로고
    • Radiation modulates the peptide repertoire, enhances MHC class I expression, and induces successful antitumor immunotherapy
    • Reits EA, Hodge JW, Herberts CA, Groothuis TA, Chakraborty M, Wansley EK, et al. Radiation modulates the peptide repertoire, enhances MHC class I expression, and induces successful antitumor immunotherapy. J Exp Med 2006;203:1259-71.
    • (2006) J Exp Med , vol.203 , pp. 1259-1271
    • Reits, E.A.1    Hodge, J.W.2    Herberts, C.A.3    Groothuis, T.A.4    Chakraborty, M.5    Wansley, E.K.6
  • 6
    • 84937525789 scopus 로고    scopus 로고
    • Local radiotherapy and granulocyte-macrophage colony-stimulating factor to generate abscopal responses in patients with metastatic solid tumours: A proof-of-principle trial
    • Golden EB, Chhabra A, Chachoua A, Adams S, Donach M, Fenton-Kerimian M, et al. Local radiotherapy and granulocyte-macrophage colony-stimulating factor to generate abscopal responses in patients with metastatic solid tumours: a proof-of-principle trial. Lancet Oncol 2015;16:795-803.
    • (2015) Lancet Oncol , vol.16 , pp. 795-803
    • Golden, E.B.1    Chhabra, A.2    Chachoua, A.3    Adams, S.4    Donach, M.5    Fenton-Kerimian, M.6
  • 7
    • 12244252335 scopus 로고    scopus 로고
    • Immune-mediated inhibition of metastases after treatment with local radiation and CTLA-4 blockade in a mouse model of breast cancer
    • Demaria S, Kawashima N, Yang AM, Devitt ML, Babb JS, Allison JP, et al. Immune-mediated inhibition of metastases after treatment with local radiation and CTLA-4 blockade in a mouse model of breast cancer. Clin Cancer Res 2005;11:728-34.
    • (2005) Clin Cancer Res , vol.11 , pp. 728-734
    • Demaria, S.1    Kawashima, N.2    Yang, A.M.3    Devitt, M.L.4    Babb, J.S.5    Allison, J.P.6
  • 8
    • 70149113060 scopus 로고    scopus 로고
    • Therapeutic effects of ablative radiation on local tumor require CD8+ T cells: Changing strategies for cancer treatment
    • Lee Y, Auh SL, Wang Y, Burnette B, Wang Y, Meng Y, et al. Therapeutic effects of ablative radiation on local tumor require CD8+ T cells: changing strategies for cancer treatment. Blood 2009;114:589-95.
    • (2009) Blood , vol.114 , pp. 589-595
    • Lee, Y.1    Auh, S.L.2    Wang, Y.3    Burnette, B.4    Wang, Y.5    Meng, Y.6
  • 9
    • 84928938600 scopus 로고    scopus 로고
    • Stereotactic radiosurgery for melanoma brain metastases in patients receiving ipilimumab: Safety profile and efficacy of combined treatment
    • Kiess AP, Wolchok JD, Barker CA, Postow MA, Tabar V, Huse JT, et al. Stereotactic radiosurgery for melanoma brain metastases in patients receiving ipilimumab: safety profile and efficacy of combined treatment. Int J Radiat Oncol Biol Phys 2015;92:368-75.
    • (2015) Int J Radiat Oncol Biol Phys , vol.92 , pp. 368-375
    • Kiess, A.P.1    Wolchok, J.D.2    Barker, C.A.3    Postow, M.A.4    Tabar, V.5    Huse, J.T.6
  • 10
    • 84901641673 scopus 로고    scopus 로고
    • Ipilimumab versus placebo after radiotherapy in patients with metastatic castration-resistant prostate cancer that had progressed after docetaxel chemotherapy (CA184-043): A multicentre, randomised, double-blind, phase 3 trial
    • Kwon ED, Drake CG, Scher HI, Fizazi K, Bossi A, van den Eertwegh AJ, et al. Ipilimumab versus placebo after radiotherapy in patients with metastatic castration-resistant prostate cancer that had progressed after docetaxel chemotherapy (CA184-043): a multicentre, randomised, double-blind, phase 3 trial. Lancet Oncol 2014;15:700-12.
    • (2014) Lancet Oncol , vol.15 , pp. 700-712
    • Kwon, E.D.1    Drake, C.G.2    Scher, H.I.3    Fizazi, K.4    Bossi, A.5    Van Den Eertwegh, A.J.6
  • 11
    • 84880508629 scopus 로고    scopus 로고
    • Ipilimumab alone or in combination with radiotherapy in metastatic castration-resistant prostate cancer: Results from an open-label, multicenter phase I/II study
    • Slovin SF, Higano CS, Hamid O, Tejwani S, Harzstark A, Alumkal JJ, et al. Ipilimumab alone or in combination with radiotherapy in metastatic castration-resistant prostate cancer: results from an open-label, multicenter phase I/II study. Ann Oncol 2013;24:1813-21.
    • (2013) Ann Oncol , vol.24 , pp. 1813-1821
    • Slovin, S.F.1    Higano, C.S.2    Hamid, O.3    Tejwani, S.4    Harzstark, A.5    Alumkal, J.J.6
  • 12
    • 84942915875 scopus 로고    scopus 로고
    • Ablative tumor radiation can change the tumor immune cell microenvironment to induce durable complete remissions
    • Filatenkov A, Baker J, Mueller AM, Kenkel J, Ahn GO, Dutt S, et al. Ablative tumor radiation can change the tumor immune cell microenvironment to induce durable complete remissions. Clin Cancer Res 2015;21:3727-39.
    • (2015) Clin Cancer Res , vol.21 , pp. 3727-3739
    • Filatenkov, A.1    Baker, J.2    Mueller, A.M.3    Kenkel, J.4    Ahn, G.O.5    Dutt, S.6
  • 13
    • 4844229902 scopus 로고    scopus 로고
    • Stereotactic hypofractionated high-dose irradiation for stage I nonsmall cell lung carcinoma: Clinical outcomes in 245 subjects in a Japanese multiinstitutional study
    • Onishi H, Araki T, Shirato H, Nagata Y, Hiraoka M, Gomi K, et al. Stereotactic hypofractionated high-dose irradiation for stage I nonsmall cell lung carcinoma: clinical outcomes in 245 subjects in a Japanese multiinstitutional study. Cancer 2004;101:1623-31.
    • (2004) Cancer , vol.101 , pp. 1623-1631
    • Onishi, H.1    Araki, T.2    Shirato, H.3    Nagata, Y.4    Hiraoka, M.5    Gomi, K.6
  • 14
    • 84897867716 scopus 로고    scopus 로고
    • Stereotactic ablative radiation therapy for centrally located early stage or isolated parenchymal recurrences of non-small cell lung cancer: How to fly in a "no fly zone"
    • Chang JY, Li QQ, Xu QY, Allen PK, Rebueno N, Gomez DR, et al. Stereotactic ablative radiation therapy for centrally located early stage or isolated parenchymal recurrences of non-small cell lung cancer: how to fly in a "no fly zone". Int J Radiat Oncol Biol Phys 2014;88:1120-8.
    • (2014) Int J Radiat Oncol Biol Phys , vol.88 , pp. 1120-1128
    • Chang, J.Y.1    Li, Q.Q.2    Xu, Q.Y.3    Allen, P.K.4    Rebueno, N.5    Gomez, D.R.6
  • 15
    • 33750612133 scopus 로고    scopus 로고
    • Excessive toxicity when treating central tumors in a phase II study of stereotactic body radiation therapy for medically inoperable early-stage lung cancer
    • Timmerman R, McGarry R, Yiannoutsos C, Papiez L, Tudor K, DeLuca J, et al. Excessive toxicity when treating central tumors in a phase II study of stereotactic body radiation therapy for medically inoperable early-stage lung cancer. J Clin Oncol 2006;24:4833-9.
    • (2006) J Clin Oncol , vol.24 , pp. 4833-4839
    • Timmerman, R.1    McGarry, R.2    Yiannoutsos, C.3    Papiez, L.4    Tudor, K.5    DeLuca, J.6
  • 16
    • 73149092567 scopus 로고    scopus 로고
    • Guidelines for the evaluation of immune therapy activity in solid tumors: Immune-related response criteria
    • Wolchok JD, Hoos A, O'Day S, Weber JS, Hamid O, Lebbe C, et al. Guidelines for the evaluation of immune therapy activity in solid tumors: immune-related response criteria. Clin Cancer Res 2009;15:7412-20.
    • (2009) Clin Cancer Res , vol.15 , pp. 7412-7420
    • Wolchok, J.D.1    Hoos, A.2    O'Day, S.3    Weber, J.S.4    Hamid, O.5    Lebbe, C.6
  • 17
    • 77952337834 scopus 로고    scopus 로고
    • Preoperative CTLA-4 blockade: Tolerability and immune monitoring in the setting of a presurgical clinical trial
    • Carthon BC, Wolchok JD, Yuan J, Kamat A, Ng Tang DS, Sun J, et al. Preoperative CTLA-4 blockade: tolerability and immune monitoring in the setting of a presurgical clinical trial. Clin Cancer Res 2010;16:2861-71.
    • (2010) Clin Cancer Res , vol.16 , pp. 2861-2871
    • Carthon, B.C.1    Wolchok, J.D.2    Yuan, J.3    Kamat, A.4    Ng Tang, D.S.5    Sun, J.6
  • 18
    • 84960158712 scopus 로고    scopus 로고
    • Immunotherapy and stereotactic ablative radiotherapy (ISABR): A curative approach?
    • Bernstein MB, Krishnan S, Hodge JW, Chang JY. Immunotherapy and stereotactic ablative radiotherapy (ISABR): a curative approach? Nat Rev Clin Oncol 2016;13:516-24.
    • (2016) Nat Rev Clin Oncol , vol.13 , pp. 516-524
    • Bernstein, M.B.1    Krishnan, S.2    Hodge, J.W.3    Chang, J.Y.4
  • 19
    • 76049093691 scopus 로고    scopus 로고
    • Impact of fraction size on lung radiation toxicity: Hypofractionation may be bene-ficial in dose escalation of radiotherapy for lung cancers
    • Jin JY, Kong FM, Chetty IJ, Ajlouni M, Ryu S, Ten Haken R, et al. Impact of fraction size on lung radiation toxicity: hypofractionation may be bene-ficial in dose escalation of radiotherapy for lung cancers. Int J Radiat Oncol Biol Phys 2010;76:782-8.
    • (2010) Int J Radiat Oncol Biol Phys , vol.76 , pp. 782-788
    • Jin, J.Y.1    Kong, F.M.2    Chetty, I.J.3    Ajlouni, M.4    Ryu, S.5    Ten Haken, R.6
  • 20
    • 84904391384 scopus 로고    scopus 로고
    • Immunotherapy for brain cancer: Recent progress and future promise
    • Jackson CM, Lim M, Drake CG. Immunotherapy for brain cancer: recent progress and future promise. Clin Cancer Res 2014;20:3651-9.
    • (2014) Clin Cancer Res , vol.20 , pp. 3651-3659
    • Jackson, C.M.1    Lim, M.2    Drake, C.G.3
  • 21
    • 79959772576 scopus 로고    scopus 로고
    • Ipilimumab plus dacarbazine for previously untreated metastatic melanoma
    • Robert C, Thomas L, Bondarenko I, O'Day S, Weber J, Garbe C, et al. Ipilimumab plus dacarbazine for previously untreated metastatic melanoma. N Engl J Med 2011;364:2517-26.
    • (2011) N Engl J Med , vol.364 , pp. 2517-2526
    • Robert, C.1    Thomas, L.2    Bondarenko, I.3    O'Day, S.4    Weber, J.5    Garbe, C.6
  • 22
    • 0035054387 scopus 로고    scopus 로고
    • Deficient DNA mismatch repair: A common etiologic factor for colon cancer
    • Peltomaki P. Deficient DNA mismatch repair: a common etiologic factor for colon cancer. Hum Mol Genet 2001;10:735-40.
    • (2001) Hum Mol Genet , vol.10 , pp. 735-740
    • Peltomaki, P.1
  • 23
    • 77958050577 scopus 로고    scopus 로고
    • Phase 2 trial of single agent Ipilimumab (anti-CTLA-4) for locally advanced or metastatic pancreatic adenocarcinoma
    • Royal RE, Levy C, Turner K, Mathur A, Hughes M, Kammula US, et al. Phase 2 trial of single agent Ipilimumab (anti-CTLA-4) for locally advanced or metastatic pancreatic adenocarcinoma. J Immunother 2010;33:828-33.
    • (2010) J Immunother , vol.33 , pp. 828-833
    • Royal, R.E.1    Levy, C.2    Turner, K.3    Mathur, A.4    Hughes, M.5    Kammula, U.S.6
  • 27
    • 84982752093 scopus 로고    scopus 로고
    • PD-1 expression conditions T cell avidity within an antigen-specific repertoire
    • Simon S, Vignard V, Florenceau L, Dreno B, Khammari A, Lang F, et al. PD-1 expression conditions T cell avidity within an antigen-specific repertoire. Oncoimmunology 2016;5:e1104448.
    • (2016) Oncoimmunology , vol.5 , pp. e1104448
    • Simon, S.1    Vignard, V.2    Florenceau, L.3    Dreno, B.4    Khammari, A.5    Lang, F.6
  • 28
    • 84879645728 scopus 로고    scopus 로고
    • Radiation and immunotherapy: A synergistic combination
    • Kalbasi A, June CH, Haas N, Vapiwala N. Radiation and immunotherapy: a synergistic combination. J Clin Invest 2013;123:2756-63.
    • (2013) J Clin Invest , vol.123 , pp. 2756-2763
    • Kalbasi, A.1    June, C.H.2    Haas, N.3    Vapiwala, N.4
  • 29
    • 0035399581 scopus 로고    scopus 로고
    • Enhancement of CD8+ T cell responses by ICOS/B7h costimulation
    • Wallin JJ, Liang L, Bakardjiev A, Sha WC. Enhancement of CD8+ T cell responses by ICOS/B7h costimulation. J Immunol 2001;167:132-9.
    • (2001) J Immunol , vol.167 , pp. 132-139
    • Wallin, J.J.1    Liang, L.2    Bakardjiev, A.3    Sha, W.C.4
  • 30
    • 38449114329 scopus 로고    scopus 로고
    • Glucocorticoid-induced TNFR-related protein lowers the threshold of CD28 costimulation in CD8+ T cells
    • Ronchetti S, Nocentini G, Bianchini R, Krausz LT, Migliorati G, Riccardi C. Glucocorticoid-induced TNFR-related protein lowers the threshold of CD28 costimulation in CD8+ T cells. J Immunol 2007;179: 5916-26.
    • (2007) J Immunol , vol.179 , pp. 5916-5926
    • Ronchetti, S.1    Nocentini, G.2    Bianchini, R.3    Krausz, L.T.4    Migliorati, G.5    Riccardi, C.6
  • 31
    • 36048963838 scopus 로고    scopus 로고
    • LAG-3 regulates CD8+ T cell accumulation and effector function in murine self-and tumor-tolerance systems
    • Grosso JF, Kelleher CC, Harris TJ, Maris CH, Hipkiss EL, De Marzo A, et al. LAG-3 regulates CD8+ T cell accumulation and effector function in murine self-and tumor-tolerance systems. J Clin Invest 2007;117: 3383-92.
    • (2007) J Clin Invest , vol.117 , pp. 3383-3392
    • Grosso, J.F.1    Kelleher, C.C.2    Harris, T.J.3    Maris, C.H.4    Hipkiss, E.L.5    De Marzo, A.6
  • 32
    • 0242708767 scopus 로고    scopus 로고
    • Tim-3 inhibits T helper type 1-mediated auto-and alloimmune responses and promotes immunological tolerance
    • Sanchez-Fueyo A, Tian J, Picarella D, Domenig C, Zheng XX, Sabatos CA, et al. Tim-3 inhibits T helper type 1-mediated auto-and alloimmune responses and promotes immunological tolerance. Nat Immunol 2003;4:1093-101.
    • (2003) Nat Immunol , vol.4 , pp. 1093-1101
    • Sanchez-Fueyo, A.1    Tian, J.2    Picarella, D.3    Domenig, C.4    Zheng, X.X.5    Sabatos, C.A.6
  • 33
    • 84874889330 scopus 로고    scopus 로고
    • Clinical development of immunostimulatory monoclonal antibodies and opportunities for combination
    • Melero I, Grimaldi AM, Perez-Gracia JL, Ascierto PA. Clinical development of immunostimulatory monoclonal antibodies and opportunities for combination. Clin Cancer Res 2013;19:997-1008.
    • (2013) Clin Cancer Res , vol.19 , pp. 997-1008
    • Melero, I.1    Grimaldi, A.M.2    Perez-Gracia, J.L.3    Ascierto, P.A.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.