메뉴 건너뛰기




Volumn 4, Issue 12, 2016, Pages 1007-1015

Endogenous neoantigen-specific CD8 T cells identified in two glioblastoma models using a cancer immunogenomics approach

Author keywords

[No Author keywords available]

Indexed keywords

E2F8 K272R ANTIGEN; EPITOPE; GAMMA INTERFERON; IMP3 D81N ANTIGEN; ODC1 Q129L ANTIGEN; TETRAMER; TUMOR ANTIGEN; UNCLASSIFIED DRUG;

EID: 85016116971     PISSN: 23266066     EISSN: 23266074     Source Type: Journal    
DOI: 10.1158/2326-6066.CIR-16-0156     Document Type: Article
Times cited : (82)

References (54)
  • 4
    • 77952294428 scopus 로고    scopus 로고
    • Small molecule kinase inhibitors in glioblastoma: A systematic review of clinical studies
    • De Witt Hamer PC. Small molecule kinase inhibitors in glioblastoma: A systematic review of clinical studies. Neuro Oncol 2010;12:304-16.
    • (2010) Neuro Oncol , vol.12 , pp. 304-316
    • De Witt-Hamer, P.C.1
  • 5
    • 84966771330 scopus 로고    scopus 로고
    • Targeting T cell co-receptors for cancer therapy
    • Callahan MK, Postow MA, Wolchok JD. Targeting T cell co-receptors for cancer therapy. Immunity 2016;44:1069-78.
    • (2016) Immunity , vol.44 , pp. 1069-1078
    • Callahan, M.K.1    Postow, M.A.2    Wolchok, J.D.3
  • 6
    • 85016925179 scopus 로고    scopus 로고
    • Principles of immunology and its nuances in the central nervous system
    • Dunn GP, Okada H. Principles of immunology and its nuances in the central nervous system. Neuro Oncol 2015;17:vii3-vii8.
    • (2015) Neuro Oncol , vol.17 , pp. vii3-vii8
    • Dunn, G.P.1    Okada, H.2
  • 7
    • 70350236627 scopus 로고    scopus 로고
    • An epidermal growth factor receptor variant III-targeted vaccine is safe and immunogenic in patients with glioblastoma multiforme
    • Sampson JH, Archer GE, Mitchell DA, Heimberger AB, Herndon JE II, Lally-Goss D, et al. An epidermal growth factor receptor variant III-targeted vaccine is safe and immunogenic in patients with glioblastoma multiforme. Mol Cancer Ther 2009;8:2773-9.
    • (2009) Mol Cancer Ther , vol.8 , pp. 2773-2779
    • Sampson, J.H.1    Archer, G.E.2    Mitchell, D.A.3    Heimberger, A.B.4    Herndon, J.E.5    Lally-Goss, D.6
  • 8
    • 84872498982 scopus 로고    scopus 로고
    • Phase I trial of a multi-epitope-pulsed dendritic cell vaccine for patients with newly diagnosed glioblastoma
    • Phuphanich S, Wheeler CJ, Rudnick JD, Mazer M, Wang H, Nuno MA, et al. Phase I trial of a multi-epitope-pulsed dendritic cell vaccine for patients with newly diagnosed glioblastoma. Cancer Immunol Immunother 2013;62:125-35.
    • (2013) Cancer Immunol Immunother , vol.62 , pp. 125-135
    • Phuphanich, S.1    Wheeler, C.J.2    Rudnick, J.D.3    Mazer, M.4    Wang, H.5    Nuno, M.A.6
  • 9
    • 84937524417 scopus 로고    scopus 로고
    • Dendritic cell immunotherapy for brain tumors
    • Antonios JP, Everson RG, Liau LM. Dendritic cell immunotherapy for brain tumors. J Neurooncol 2015;123:425-32.
    • (2015) J Neurooncol , vol.123 , pp. 425-432
    • Antonios, J.P.1    Everson, R.G.2    Liau, L.M.3
  • 10
    • 84893073441 scopus 로고    scopus 로고
    • Heat-shock protein peptide complex-96 vaccination for recurrent glioblastoma: A phase II, single-arm trial
    • Bloch O, Crane CA, Fuks Y, Kaur R, Aghi MK, Berger MS, et al. Heat-shock protein peptide complex-96 vaccination for recurrent glioblastoma: A phase II, single-arm trial. Neuro Oncol 2014;16:274-9.
    • (2014) Neuro Oncol , vol.16 , pp. 274-279
    • Bloch, O.1    Crane, C.A.2    Fuks, Y.3    Kaur, R.4    Aghi, M.K.5    Berger, M.S.6
  • 11
    • 84941710020 scopus 로고    scopus 로고
    • Tumor neoantigens: Building a framework for personalized cancer immunotherapy
    • Gubin MM, Artyomov MN, Mardis ER, Schreiber RD. Tumor neoantigens: Building a framework for personalized cancer immunotherapy. J Clin Invest 2015;125:3413-21.
    • (2015) J Clin Invest , vol.125 , pp. 3413-3421
    • Gubin, M.M.1    Artyomov, M.N.2    Mardis, E.R.3    Schreiber, R.D.4
  • 15
    • 84920921528 scopus 로고    scopus 로고
    • Checkpoint blockade cancer immunotherapy targets tumour-specific mutant antigens
    • Gubin MM, Zhang X, Schuster H, Caron E, Ward JP, Noguchi T, et al. Checkpoint blockade cancer immunotherapy targets tumour-specific mutant antigens. Nature 2014;515:577-81.
    • (2014) Nature , vol.515 , pp. 577-581
    • Gubin, M.M.1    Zhang, X.2    Schuster, H.3    Caron, E.4    Ward, J.P.5    Noguchi, T.6
  • 17
    • 84920956731 scopus 로고    scopus 로고
    • Predicting immunogenic tumour mutations by combining mass spectrometry and exome sequencing
    • Yadav M, Jhunjhunwala S, Phung QT, Lupardus P, Tanguay J, Bumbaca S, et al. Predicting immunogenic tumour mutations by combining mass spectrometry and exome sequencing. Nature 2014;515:572-6.
    • (2014) Nature , vol.515 , pp. 572-576
    • Yadav, M.1    Jhunjhunwala, S.2    Phung, Q.T.3    Lupardus, P.4    Tanguay, J.5    Bumbaca, S.6
  • 18
    • 84880276438 scopus 로고    scopus 로고
    • Mining exomic sequencing data to identify mutated antigens recognized by adoptively transferred tumor-reactive T cells
    • Robbins PF, Lu YC, El-Gamil M, Li YF, Gross C, Gartner J, et al. Mining exomic sequencing data to identify mutated antigens recognized by adoptively transferred tumor-reactive T cells. Nat Med 2013;19:747-52.
    • (2013) Nat Med , vol.19 , pp. 747-752
    • Robbins, P.F.1    Lu, Y.C.2    El-Gamil, M.3    Li, Y.F.4    Gross, C.5    Gartner, J.6
  • 19
    • 84872841412 scopus 로고    scopus 로고
    • Tumor exome analysis reveals neoantigen-specific T-cell reactivity in an ipilimumab-responsive melanoma
    • van Rooij N, van Buuren MM, Philips D, Velds A, Toebes M, Heemskerk B, et al. Tumor exome analysis reveals neoantigen-specific T-cell reactivity in an ipilimumab-responsive melanoma. J Clin Oncol 2013;31: e439-42.
    • (2013) J Clin Oncol , vol.31 , pp. e439-e442
    • Van Rooij, N.1    Van Buuren, M.M.2    Philips, D.3    Velds, A.4    Toebes, M.5    Heemskerk, B.6
  • 20
    • 84928761118 scopus 로고    scopus 로고
    • Cancer immunology. Mutational landscape determines sensitivity to PD-1 blockade in non-small cell lung cancer
    • Rizvi NA, Hellmann MD, Snyder A, Kvistborg P, Makarov V, Havel JJ, et al. Cancer immunology. Mutational landscape determines sensitivity to PD-1 blockade in non-small cell lung cancer. Science 2015;348:124-8.
    • (2015) Science , vol.348 , pp. 124-128
    • Rizvi, N.A.1    Hellmann, M.D.2    Snyder, A.3    Kvistborg, P.4    Makarov, V.5    Havel, J.J.6
  • 21
    • 84900301377 scopus 로고    scopus 로고
    • Cancer immunotherapy based on mutation-specific CD4+T cells in a patient with epithelial cancer
    • Tran E, Turcotte S, Gros A, Robbins PF, Lu YC, Dudley ME, et al. Cancer immunotherapy based on mutation-specific CD4+T cells in a patient with epithelial cancer. Science 2014;344:641-5.
    • (2014) Science , vol.344 , pp. 641-645
    • Tran, E.1    Turcotte, S.2    Gros, A.3    Robbins, P.F.4    Lu, Y.C.5    Dudley, M.E.6
  • 22
    • 0014851851 scopus 로고
    • Studies on the chemotherapy of experimental brain tumors: Development of an experimental model
    • Ausman JI, Shapiro WR, Rall DP. Studies on the chemotherapy of experimental brain tumors: Development of an experimental model. Cancer Res 1970;30:2394-400.
    • (1970) Cancer Res , vol.30 , pp. 2394-2400
    • Ausman, J.I.1    Shapiro, W.R.2    Rall, D.P.3
  • 23
    • 0015045456 scopus 로고
    • Astrocytomas in an inbred mouse strain
    • Fraser H. Astrocytomas in an inbred mouse strain. J Pathol 1971;103: 266-70.
    • (1971) J Pathol , vol.103 , pp. 266-270
    • Fraser, H.1
  • 24
    • 34247502076 scopus 로고    scopus 로고
    • Systemic CTLA-4 blockade ameliorates glioma-induced changes to the CD4+ T cell compartment without affecting regulatory T-cell function
    • Fecci PE, Ochiai H, Mitchell DA, Grossi PM, Sweeney AE, Archer GE, et al. Systemic CTLA-4 blockade ameliorates glioma-induced changes to the CD4+ T cell compartment without affecting regulatory T-cell function. Clin Cancer Res 2007;13:2158-67.
    • (2007) Clin Cancer Res , vol.13 , pp. 2158-2167
    • Fecci, P.E.1    Ochiai, H.2    Mitchell, D.A.3    Grossi, P.M.4    Sweeney, A.E.5    Archer, G.E.6
  • 26
    • 84904061991 scopus 로고    scopus 로고
    • Durable therapeutic efficacy utilizing combinatorial blockade against IDO, CTLA-4 and PD-L1 in mice with brain tumors
    • Wainwright DA, Chang AL, Dey M, Balyasnikova IV, Kim C, Tobias AL, et al. Durable therapeutic efficacy utilizing combinatorial blockade against IDO, CTLA-4 and PD-L1 in mice with brain tumors. Clin Cancer Res 2014;20: 5290-301.
    • (2014) Clin Cancer Res , vol.20 , pp. 5290-5301
    • Wainwright, D.A.1    Chang, A.L.2    Dey, M.3    Balyasnikova, I.V.4    Kim, C.5    Tobias, A.L.6
  • 27
    • 84877581852 scopus 로고    scopus 로고
    • Anti-PD-1 blockade and stereotactic radiation produce long-term survival in mice with intracranial gliomas
    • Zeng J, See AP, Phallen J, Jackson CM, Belcaid Z, Ruzevick J, et al. Anti-PD-1 blockade and stereotactic radiation produce long-term survival in mice with intracranial gliomas. Int J Radiat Oncol Biol Phys 2013; 86:343-9.
    • (2013) Int J Radiat Oncol Biol Phys , vol.86 , pp. 343-349
    • Zeng, J.1    See, A.P.2    Phallen, J.3    Jackson, C.M.4    Belcaid, Z.5    Ruzevick, J.6
  • 28
    • 84904207094 scopus 로고    scopus 로고
    • Focal radiation therapy combined with 4-1BB activation and CTLA-4 blockade yields long-term survival and a protective antigen-specific memory response in a murine glioma model
    • Belcaid Z, Phallen JA, Zeng J, See AP, Mathios D, Gottschalk C, et al. Focal radiation therapy combined with 4-1BB activation and CTLA-4 blockade yields long-term survival and a protective antigen-specific memory response in a murine glioma model. PLoS One 2014;9:e101764.
    • (2014) PLoS One , vol.9 , pp. e101764
    • Belcaid, Z.1    Phallen, J.A.2    Zeng, J.3    See, A.P.4    Mathios, D.5    Gottschalk, C.6
  • 29
    • 67649884743 scopus 로고    scopus 로고
    • Fast and accurate short read alignment with Burrows-Wheeler transform
    • Li H, Durbin R. Fast and accurate short read alignment with Burrows-Wheeler transform. Bioinformatics 2009;25:1754-60.
    • (2009) Bioinformatics , vol.25 , pp. 1754-1760
    • Li, H.1    Durbin, R.2
  • 32
    • 84863229597 scopus 로고    scopus 로고
    • VarScan 2: Somatic mutation and copy number alteration discovery in cancer by exome sequencing
    • Koboldt DC, Zhang Q, Larson DE, Shen D, McLellan MD, Lin L, et al. VarScan 2: Somatic mutation and copy number alteration discovery in cancer by exome sequencing. Genome Res 2012;22:568-76.
    • (2012) Genome Res , vol.22 , pp. 568-576
    • Koboldt, D.C.1    Zhang, Q.2    Larson, D.E.3    Shen, D.4    McLellan, M.D.5    Lin, L.6
  • 33
  • 34
    • 77956295988 scopus 로고    scopus 로고
    • The genome analysis toolkit: A MapReduce framework for analyzing next-generation DNA sequencing data
    • McKenna A, Hanna M, Banks E, Sivachenko A, Cibulskis K, Kernytsky A, et al. The Genome Analysis Toolkit: A MapReduce framework for analyzing next-generation DNA sequencing data. Genome Res 2010;20:1297-303.
    • (2010) Genome Res , vol.20 , pp. 1297-1303
    • McKenna, A.1    Hanna, M.2    Banks, E.3    Sivachenko, A.4    Cibulskis, K.5    Kernytsky, A.6
  • 36
    • 41649096341 scopus 로고    scopus 로고
    • Conditional MHC class I ligands and peptide exchange technology for the human MHC gene products HLA-A1, -A3, -A11, and-B7
    • Bakker AH, Hoppes R, Linnemann C, Toebes M, Rodenko B, Berkers CR, et al. Conditional MHC class I ligands and peptide exchange technology for the human MHC gene products HLA-A1, -A3, -A11, and-B7. Proc Natl Acad Sci USA 2008;105:3825-30.
    • (2008) Proc Natl Acad Sci USA , vol.105 , pp. 3825-3830
    • Bakker, A.H.1    Hoppes, R.2    Linnemann, C.3    Toebes, M.4    Rodenko, B.5    Berkers, C.R.6
  • 37
    • 84936871460 scopus 로고    scopus 로고
    • Structural and functional features of central nervous system lymphatic vessels
    • Louveau A, Smirnov I, Keyes TJ, Eccles JD, Rouhani SJ, Peske JD, et al. Structural and functional features of central nervous system lymphatic vessels. Nature 2015;523:337-41.
    • (2015) Nature , vol.523 , pp. 337-341
    • Louveau, A.1    Smirnov, I.2    Keyes, T.J.3    Eccles, J.D.4    Rouhani, S.J.5    Peske, J.D.6
  • 38
    • 0026929035 scopus 로고
    • Drainage of brain extracellular fluid into blood and deep cervical lymph and its immunological significance
    • Cserr HF, Harling-Berg CJ, Knopf PM. Drainage of brain extracellular fluid into blood and deep cervical lymph and its immunological significance. Brain Pathol 1992;2:269-76.
    • (1992) Brain Pathol , vol.2 , pp. 269-276
    • Cserr, H.F.1    Harling-Berg, C.J.2    Knopf, P.M.3
  • 39
    • 84864267012 scopus 로고    scopus 로고
    • Cancer immunoediting in malignant glioma
    • discussion 22-3
    • Dunn GP, Fecci PE, Curry WT. Cancer immunoediting in malignant glioma. Neurosurgery 2012;71:201-22; discussion 22-3.
    • (2012) Neurosurgery , vol.71 , pp. 201-222
    • Dunn, G.P.1    Fecci, P.E.2    Curry, W.T.3
  • 40
    • 84894559188 scopus 로고    scopus 로고
    • Tumour antigens recognized by T lymphocytes: At the core of cancer immunotherapy
    • Coulie PG, Van den Eynde BJ, van der Bruggen P, Boon T. Tumour antigens recognized by T lymphocytes: At the core of cancer immunotherapy. Nat Rev Cancer 2014;14:135-46.
    • (2014) Nat Rev Cancer , vol.14 , pp. 135-146
    • Coulie, P.G.1    Van Den-Eynde, B.J.2    Van Der-Bruggen, P.3    Boon, T.4
  • 41
    • 57149098994 scopus 로고    scopus 로고
    • ODC1 is a critical determinant of MYCN oncogenesis and a therapeutic target in neuroblastoma
    • Hogarty MD, Norris MD, Davis K, Liu X, Evageliou NF, Hayes CS, et al. ODC1 is a critical determinant of MYCN oncogenesis and a therapeutic target in neuroblastoma. Cancer Res 2008;68:9735-45.
    • (2008) Cancer Res , vol.68 , pp. 9735-9745
    • Hogarty, M.D.1    Norris, M.D.2    Davis, K.3    Liu, X.4    Evageliou, N.F.5    Hayes, C.S.6
  • 42
    • 84959542726 scopus 로고    scopus 로고
    • IMP3 promotes stem-like properties in triple-negative breast cancer by regulating SLUG
    • Samanta S, Sun H, Goel HL, Pursell B, Chang C, Khan A, et al. IMP3 promotes stem-like properties in triple-negative breast cancer by regulating SLUG. Oncogene 2016;35:1111-21.
    • (2016) Oncogene , vol.35 , pp. 1111-1121
    • Samanta, S.1    Sun, H.2    Goel, H.L.3    Pursell, B.4    Chang, C.5    Khan, A.6
  • 44
    • 42549105195 scopus 로고    scopus 로고
    • Evaluation of MHC class I peptide binding prediction servers: Applications for vaccine research
    • Lin HH, Ray S, Tongchusak S, Reinherz EL, Brusic V. Evaluation of MHC class I peptide binding prediction servers: Applications for vaccine research. BMC Immunol 2008;9:8.
    • (2008) BMC Immunol , vol.9 , pp. 8
    • Lin, H.H.1    Ray, S.2    Tongchusak, S.3    Reinherz, E.L.4    Brusic, V.5
  • 45
    • 83155180577 scopus 로고    scopus 로고
    • Toward more accurate pan-specific MHC-peptide binding prediction: A review of current methods and tools
    • Zhang L, Udaka K, Mamitsuka H, Zhu S. Toward more accurate pan-specific MHC-peptide binding prediction: A review of current methods and tools. Brief Bioinform 2012;13:350-64.
    • (2012) Brief Bioinform , vol.13 , pp. 350-364
    • Zhang, L.1    Udaka, K.2    Mamitsuka, H.3    Zhu, S.4
  • 46
    • 31544460152 scopus 로고    scopus 로고
    • Identification of a glioma antigen, GARC-1, using cytotoxic T lymphocytes induced by HSV cancer vaccine
    • Izuka Y, Kojima H, Kobata T, Kawase T, Kawakami Y, Toda M. Identification of a glioma antigen, GARC-1, using cytotoxic T lymphocytes induced by HSV cancer vaccine. Int J Cancer 2006;118:942-9.
    • (2006) Int J Cancer , vol.118 , pp. 942-949
    • Izuka, Y.1    Kojima, H.2    Kobata, T.3    Kawase, T.4    Kawakami, Y.5    Toda, M.6
  • 47
    • 84942469639 scopus 로고    scopus 로고
    • A dural lymphatic vascular system that drains brain interstitial fluid and macromolecules
    • Aspelund A, Antila S, Proulx ST, Karlsen TV, Karaman S, Detmar M, et al. A dural lymphatic vascular system that drains brain interstitial fluid and macromolecules. J Exp Med 2015;212:991-9.
    • (2015) J Exp Med , vol.212 , pp. 991-999
    • Aspelund, A.1    Antila, S.2    Proulx, S.T.3    Karlsen, T.V.4    Karaman, S.5    Detmar, M.6
  • 48
    • 84928195112 scopus 로고    scopus 로고
    • A dendritic cell vaccine increases the breadth and diversity of melanoma neoantigen-specific T cells
    • Carreno BM, Magrini V, Becker-Hapak M, Kaabinejadian S, Hundal J, Petti AA, et al. A dendritic cell vaccine increases the breadth and diversity of melanoma neoantigen-specific T cells. Science 2015;348:803-8.
    • (2015) Science , vol.348 , pp. 803-808
    • Carreno, B.M.1    Magrini, V.2    Becker-Hapak, M.3    Kaabinejadian, S.4    Hundal, J.5    Petti, A.A.6
  • 49
    • 34247499001 scopus 로고    scopus 로고
    • Loss of the mismatch repair protein MSH6 in human glioblastomas is associated with tumor progression during temozolomide treatment
    • Cahill DP, Levine KK, Betensky RA, Codd PJ, Romany CA, Reavie LB, et al. Loss of the mismatch repair protein MSH6 in human glioblastomas is associated with tumor progression during temozolomide treatment. Clin Cancer Res 2007;13:2038-45.
    • (2007) Clin Cancer Res , vol.13 , pp. 2038-2045
    • Cahill, D.P.1    Levine, K.K.2    Betensky, R.A.3    Codd, P.J.4    Romany, C.A.5    Reavie, L.B.6
  • 50
    • 33646256145 scopus 로고    scopus 로고
    • A hypermutation phenotype and somatic MSH6 mutations in recurrent humanmalignant gliomas after alkylator chemotherapy
    • Hunter C, Smith R, Cahill DP, Stephens P, Stevens C, Teague J, et al. A hypermutation phenotype and somatic MSH6 mutations in recurrent humanmalignant gliomas after alkylator chemotherapy. Cancer Res 2006; 66:3987-91.
    • (2006) Cancer Res , vol.66 , pp. 3987-3991
    • Hunter, C.1    Smith, R.2    Cahill, D.P.3    Stephens, P.4    Stevens, C.5    Teague, J.6
  • 51
    • 84892373020 scopus 로고    scopus 로고
    • Mutational analysis reveals the origin and therapy-driven evolution of recurrent glioma
    • Johnson BE, Mazor T, Hong C, Barnes M, Aihara K, McLean CY, et al. Mutational analysis reveals the origin and therapy-driven evolution of recurrent glioma. Science 2014;343:189-93.
    • (2014) Science , vol.343 , pp. 189-193
    • Johnson, B.E.1    Mazor, T.2    Hong, C.3    Barnes, M.4    Aihara, K.5    McLean, C.Y.6
  • 52
    • 84939992139 scopus 로고    scopus 로고
    • Evolution of DNA repair defects during malignant progression of lowgrade gliomas after temozolomide treatment
    • van Thuijl HF, Mazor T, Johnson BE, Fouse SD, Aihara K, Hong C, et al. Evolution of DNA repair defects during malignant progression of lowgrade gliomas after temozolomide treatment. Acta Neuropathol 2015;129: 597-607.
    • (2015) Acta Neuropathol , vol.129 , pp. 597-607
    • Van Thuijl, H.F.1    Mazor, T.2    Johnson, B.E.3    Fouse, S.D.4    Aihara, K.5    Hong, C.6
  • 53


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.