-
1
-
-
84923617290
-
Synovial sarcoma: Defining features and diagnostic evolution
-
Thway K, Fisher C. Synovial sarcoma: Defining features and diagnostic evolution. Ann Diagn Pathol 2014;18:369-80.
-
(2014)
Ann Diagn Pathol
, vol.18
, pp. 369-380
-
-
Thway, K.1
Fisher, C.2
-
2
-
-
79251579648
-
Synovial sarcomas usually metastasize after >5 years: A multicenter retrospective analysis with minimum follow-up of 10 years for survivors
-
Krieg AH, Hefti F, Speth BM, Jundt G, Guillou L, Exner UG, et al. Synovial sarcomas usually metastasize after >5 years: A multicenter retrospective analysis with minimum follow-up of 10 years for survivors. Ann Oncol 2011;22:458-67.
-
(2011)
Ann Oncol
, vol.22
, pp. 458-467
-
-
Krieg, A.H.1
Hefti, F.2
Speth, B.M.3
Jundt, G.4
Guillou, L.5
Exner, U.G.6
-
3
-
-
0038668852
-
Updates on the cytogenetics and molecular genetics of bone and soft tissue tumors: Chondrosarcoma and other cartilaginous neoplasms
-
Sandberg AA, Bridge JA. Updates on the cytogenetics and molecular genetics of bone and soft tissue tumors: Chondrosarcoma and other cartilaginous neoplasms. Cancer Genet Cytogenet 2003;143:1-31.
-
(2003)
Cancer Genet Cytogenet
, vol.143
, pp. 1-31
-
-
Sandberg, A.A.1
Bridge, J.A.2
-
4
-
-
84977074161
-
Tetramer guided, cell sorter assisted production of clinical grade autologous NY-ESO-1 specific CD8(+) T cells
-
Pollack SM, Jones RL, Farrar EA, Lai IP, Lee SM, Cao J, et al. Tetramer guided, cell sorter assisted production of clinical grade autologous NY-ESO-1 specific CD8(+) T cells. J Immunother Cancer 2014;2:36.
-
(2014)
J Immunother Cancer
, vol.2
, pp. 36
-
-
Pollack, S.M.1
Jones, R.L.2
Farrar, E.A.3
Lai, I.P.4
Lee, S.M.5
Cao, J.6
-
5
-
-
45549099784
-
Treatment of metastatic melanoma with autologous CD4+ T cells against NY-ESO-1
-
Hunder NN, Wallen H, Cao J, Hendricks DW, Reilly JZ, Rodmyre R, et al. Treatment of metastatic melanoma with autologous CD4+ T cells against NY-ESO-1. N Engl J Med 2008;358:2698-703.
-
(2008)
N Engl J Med
, vol.358
, pp. 2698-2703
-
-
Hunder, N.N.1
Wallen, H.2
Cao, J.3
Hendricks, D.W.4
Reilly, J.Z.5
Rodmyre, R.6
-
6
-
-
84928912377
-
A pilot trial using lymphocytes genetically engineered with an NY-ESO-1-reactive T-cell receptor: Long-term follow-up and correlates with response
-
Robbins PF, Kassim SH, Tran TL, Crystal JS, Morgan RA, Feldman SA, et al. A pilot trial using lymphocytes genetically engineered with an NY-ESO-1-reactive T-cell receptor: Long-term follow-up and correlates with response. Clin Cancer Res 2015;21:1019-27.
-
(2015)
Clin Cancer Res
, vol.21
, pp. 1019-1027
-
-
Robbins, P.F.1
Kassim, S.H.2
Tran, T.L.3
Crystal, J.S.4
Morgan, R.A.5
Feldman, S.A.6
-
7
-
-
85016117264
-
Phase 1 first-in-human trial of LV305 in patients with advanced ormetastatic cancer expressing NY-ESO-1
-
abstr 3021
-
Somaiah N, Block MS, Kim JW, Shapiro G, Hwu P, Eder JP, et al. Phase 1 first-in-human trial of LV305 in patients with advanced ormetastatic cancer expressing NY-ESO-1. J Clin Oncol 2015;33:abstr 3021.
-
(2015)
J Clin Oncol
, pp. 33
-
-
Somaiah, N.1
Block, M.S.2
Kim, J.W.3
Shapiro, G.4
Hwu, P.5
Eder, J.P.6
-
8
-
-
84862882003
-
Tumor immunotherapy directed at PD-1
-
Ribas A. Tumor immunotherapy directed at PD-1. N Engl J Med 2012; 366:2517-9.
-
(2012)
N Engl J Med
, vol.366
, pp. 2517-2519
-
-
Ribas, A.1
-
9
-
-
33645846313
-
Tissue expression of PD-L1 mediates peripheral T cell tolerance
-
Keir ME, Liang SC, Guleria I, Latchman YE, Qipo A, Albacker LA, et al. Tissue expression of PD-L1 mediates peripheral T cell tolerance. J Exp Med 2006; 203:883-95.
-
(2006)
J Exp Med
, vol.203
, pp. 883-895
-
-
Keir, M.E.1
Liang, S.C.2
Guleria, I.3
Latchman, Y.E.4
Qipo, A.5
Albacker, L.A.6
-
10
-
-
77953747963
-
The PD-1 pathway in tolerance and autoimmunity
-
Francisco LM, Sage PT, Sharpe AH. The PD-1 pathway in tolerance and autoimmunity. Immunol Rev 2010;236:219-42.
-
(2010)
Immunol Rev
, vol.236
, pp. 219-242
-
-
Francisco, L.M.1
Sage, P.T.2
Sharpe, A.H.3
-
11
-
-
70350433514
-
Interactions between PD-1 and PD-L1 promote tolerance by blocking the TCR-induced stop signal
-
Fife BT, Pauken KE, Eagar TN, Obu T, Wu J, Tang Q, et al. Interactions between PD-1 and PD-L1 promote tolerance by blocking the TCR-induced stop signal. Nat Immunol 2009;10:1185-92.
-
(2009)
Nat Immunol
, vol.10
, pp. 1185-1192
-
-
Fife, B.T.1
Pauken, K.E.2
Eagar, T.N.3
Obu, T.4
Wu, J.5
Tang, Q.6
-
12
-
-
84858766182
-
The blockade of immune checkpoints in cancer immunotherapy
-
Pardoll DM. The blockade of immune checkpoints in cancer immunotherapy. Nat Rev Cancer 2012;12:252-64.
-
(2012)
Nat Rev Cancer
, vol.12
, pp. 252-264
-
-
Pardoll, D.M.1
-
13
-
-
84879759020
-
Safety and tumor responses with lambrolizumab (anti-PD-1) in melanoma
-
Hamid O, Robert C, Daud A, Hodi FS, Hwu WJ, Kefford R, et al. Safety and tumor responses with lambrolizumab (anti-PD-1) in melanoma. N Engl J Med 2013;369:134-44.
-
(2013)
N Engl J Med
, vol.369
, pp. 134-144
-
-
Hamid, O.1
Robert, C.2
Daud, A.3
Hodi, F.S.4
Hwu, W.J.5
Kefford, R.6
-
14
-
-
84908354848
-
Antiprogrammed-death-receptor-1 treatment with pembrolizumab in ipilimumab-refractory advanced melanoma: A randomised dose-comparison cohort of a phase 1 trial
-
Robert C, Ribas A, Wolchok JD, Hodi FS, Hamid O, Kefford R, et al. Antiprogrammed-death-receptor-1 treatment with pembrolizumab in ipilimumab-refractory advanced melanoma: A randomised dose-comparison cohort of a phase 1 trial. Lancet 2014;384:1109-17.
-
(2014)
Lancet
, vol.384
, pp. 1109-1117
-
-
Robert, C.1
Ribas, A.2
Wolchok, J.D.3
Hodi, F.S.4
Hamid, O.5
Kefford, R.6
-
16
-
-
84862859820
-
Safety, activity, and immune correlates of anti-PD-1 antibody in cancer
-
Topalian SL, Hodi FS, Brahmer JR, Gettinger SN, Smith DC, McDermott DF, et al. Safety, activity, and immune correlates of anti-PD-1 antibody in cancer. N Engl J Med 2012;366:2443-54.
-
(2012)
N Engl J Med
, vol.366
, pp. 2443-2454
-
-
Topalian, S.L.1
Hodi, F.S.2
Brahmer, J.R.3
Gettinger, S.N.4
Smith, D.C.5
McDermott, D.F.6
-
17
-
-
84862903106
-
Safety and activity of anti-PD-L1 antibody in patients with advanced cancer
-
Brahmer JR, Tykodi SS, Chow LQ, Hwu WJ, Topalian SL, Hwu P, et al. Safety and activity of anti-PD-L1 antibody in patients with advanced cancer. N Engl J Med 2012;366:2455-65.
-
(2012)
N Engl J Med
, vol.366
, pp. 2455-2465
-
-
Brahmer, J.R.1
Tykodi, S.S.2
Chow, L.Q.3
Hwu, W.J.4
Topalian, S.L.5
Hwu, P.6
-
18
-
-
84890096527
-
Disabling immune tolerance by programmed death-1 blockade with pidilizumab after autologous hematopoietic stem-cell transplantation for diffuse large B-cell lymphoma: Results of an international phase II trial
-
Armand P, Nagler A, Weller EA, Devine SM, Avigan DE, Chen YB, et al. Disabling immune tolerance by programmed death-1 blockade with pidilizumab after autologous hematopoietic stem-cell transplantation for diffuse large B-cell lymphoma: Results of an international phase II trial. J Clin Oncol 2013;31:4199-206.
-
(2013)
J Clin Oncol
, vol.31
, pp. 4199-4206
-
-
Armand, P.1
Nagler, A.2
Weller, E.A.3
Devine, S.M.4
Avigan, D.E.5
Chen, Y.B.6
-
19
-
-
84920956732
-
PD-1 blockade induces responses by inhibiting adaptive immune resistance
-
Tumeh PC, Harview CL, Yearley JH, Shintaku IP, Taylor EJ, Robert L, et al. PD-1 blockade induces responses by inhibiting adaptive immune resistance. Nature 2014;515:568-71.
-
(2014)
Nature
, vol.515
, pp. 568-571
-
-
Tumeh, P.C.1
Harview, C.L.2
Yearley, J.H.3
Shintaku, I.P.4
Taylor, E.J.5
Robert, L.6
-
20
-
-
84941347852
-
Accumulation of CD5+CD19+ B lymphocytes expressing PD-1 and PD-1L in hypertrophied pharyngeal tonsils
-
Wlasiuk P, Niedzielski A, Skorka K, Karczmarczyk A, Zaleska J, Zajac M, et al. Accumulation of CD5+CD19+ B lymphocytes expressing PD-1 and PD-1L in hypertrophied pharyngeal tonsils. Clin ExpMed 2016;16:503-9.
-
(2016)
Clin ExpMed
, vol.16
, pp. 503-509
-
-
Wlasiuk, P.1
Niedzielski, A.2
Skorka, K.3
Karczmarczyk, A.4
Zaleska, J.5
Zajac, M.6
-
21
-
-
84948668396
-
PDL1 expression on plasma and dendritic cells in myeloma bone marrow suggests benefit of targeted anti PD1-PDL1 therapy
-
Sponaas AM, Moharrami NN, Feyzi E, Standal T, Holth Rustad E, Waage A, et al. PDL1 expression on plasma and dendritic cells in myeloma bone marrow suggests benefit of targeted anti PD1-PDL1 therapy. PLoS One 2015;10:e0139867.
-
(2015)
PLoS One
, vol.10
, pp. e0139867
-
-
Sponaas, A.M.1
Moharrami, N.N.2
Feyzi, E.3
Standal, T.4
Holth Rustad, E.5
Waage, A.6
-
22
-
-
85007001788
-
Image analysis-based assessment of PD-L1 and tumor-associated immune cells density supports distinct intratumoral microenvironment groups in non-small cell lung carcinoma patients
-
Parra ER, Behrens C, Rodriguez-Canales J, Lin HY, Mino B, Blando J, et al. Image analysis-based assessment of PD-L1 and tumor-associated immune cells density supports distinct intratumoral microenvironment groups in non-small cell lung carcinoma patients. Clin Cancer Res 2016;22:6278-89.
-
(2016)
Clin Cancer Res
, vol.22
, pp. 6278-6289
-
-
Parra, E.R.1
Behrens, C.2
Rodriguez-Canales, J.3
Lin, H.Y.4
Mino, B.5
Blando, J.6
-
23
-
-
84946434271
-
The increase of circulating PD-L1-expressing CD68(+) macrophage in ovarian cancer
-
Qu QX, Huang Q, Shen Y, Zhu YB, Zhang XG. The increase of circulating PD-L1-expressing CD68(+) macrophage in ovarian cancer. Tumour Biol 2016;37:5031-7.
-
(2016)
Tumour Biol
, vol.37
, pp. 5031-5037
-
-
Qu, Q.X.1
Huang, Q.2
Shen, Y.3
Zhu, Y.B.4
Zhang, X.G.5
-
24
-
-
84904055758
-
Immune cell-poor melanomas benefit from PD-1 blockade after targeted type I IFN activation
-
Bald T, Landsberg J, Lopez-Ramos D, Renn M, Glodde N, Jansen P, et al. Immune cell-poor melanomas benefit from PD-1 blockade after targeted type I IFN activation. Cancer Discov 2014;4:674-87.
-
(2014)
Cancer Discov
, vol.4
, pp. 674-687
-
-
Bald, T.1
Landsberg, J.2
Lopez-Ramos, D.3
Renn, M.4
Glodde, N.5
Jansen, P.6
-
25
-
-
84904024273
-
Association of PD-1, PD-1 ligands, and other features of the tumor immune microenvironment with response to anti-PD-1 therapy
-
Taube JM, Klein A, Brahmer JR, Xu H, Pan X, Kim JH, et al. Association of PD-1, PD-1 ligands, and other features of the tumor immune microenvironment with response to anti-PD-1 therapy. Clin Cancer Res 2014;20: 5064-74.
-
(2014)
Clin Cancer Res
, vol.20
, pp. 5064-5074
-
-
Taube, J.M.1
Klein, A.2
Brahmer, J.R.3
Xu, H.4
Pan, X.5
Kim, J.H.6
-
26
-
-
84883863501
-
Upregulation of PD-L1, IDO, and T(regs) in the melanoma tumor microenvironment is driven by CD8(+) T cells
-
Spranger S, Spaapen RM, Zha Y, Williams J, Meng Y, Ha TT, et al. Upregulation of PD-L1, IDO, and T(regs) in the melanoma tumor microenvironment is driven by CD8(+) T cells. Sci Transl Med 2013;5:200ra116.
-
(2013)
Sci Transl Med
, vol.5
, pp. 200ra116
-
-
Spranger, S.1
Spaapen, R.M.2
Zha, Y.3
Williams, J.4
Meng, Y.5
Ha, T.T.6
-
27
-
-
84979609883
-
Immune infiltration and PD-L1 expression in the tumor microenvironment are prognostic in osteosarcoma
-
Koirala P, Roth ME, Gill J, Piperdi S, Chinai JM, Geller DS, et al. Immune infiltration and PD-L1 expression in the tumor microenvironment are prognostic in osteosarcoma. Sci Rep 2016;6:30093.
-
(2016)
Sci Rep
, vol.6
, pp. 30093
-
-
Koirala, P.1
Roth, M.E.2
Gill, J.3
Piperdi, S.4
Chinai, J.M.5
Geller, D.S.6
-
28
-
-
84975132631
-
Analysis of PD-L1, T-cell infiltrate and HLA expression in chondrosarcoma indicates potential for response to immunotherapy specifically in the dedifferentiated subtype
-
Kostine M, Cleven AH, de Miranda NF, Italiano A, Cleton-Jansen AM, Bovee JV. Analysis of PD-L1, T-cell infiltrate and HLA expression in chondrosarcoma indicates potential for response to immunotherapy specifically in the dedifferentiated subtype. Mod Pathol 2016;29:1028-37.
-
(2016)
Mod Pathol
, vol.29
, pp. 1028-1037
-
-
Kostine, M.1
Cleven, A.H.2
De Miranda, N.F.3
Italiano, A.4
Cleton-Jansen, A.M.5
Bovee, J.V.6
-
29
-
-
84924530574
-
Prevalence of tumor-infiltrating lymphocytes and PD-L1 expression in the soft tissue sarcoma microenvironment
-
D'Angelo SP, Shoushtari AN, Agaram NP, Kuk D, Qin LX, Carvajal RD, et al. Prevalence of tumor-infiltrating lymphocytes and PD-L1 expression in the soft tissue sarcoma microenvironment. Hum Pathol 2015;46:357-65.
-
(2015)
Hum Pathol
, vol.46
, pp. 357-365
-
-
D'Angelo, S.P.1
Shoushtari, A.N.2
Agaram, N.P.3
Kuk, D.4
Qin, L.X.5
Carvajal, R.D.6
-
30
-
-
84957667954
-
Prognostic impact of programmed cell death-1 (PD-1) and PD-ligand 1 (PD-L1) expression in cancer cells and tumor-infiltrating lymphocytes in ovarian high grade serous carcinoma
-
Darb-Esfahani S, Kunze CA, Kulbe H, Sehouli J, Wienert S, Lindner J, et al. Prognostic impact of programmed cell death-1 (PD-1) and PD-ligand 1 (PD-L1) expression in cancer cells and tumor-infiltrating lymphocytes in ovarian high grade serous carcinoma. Oncotarget 2016;7:1486-99.
-
(2016)
Oncotarget
, vol.7
, pp. 1486-1499
-
-
Darb-Esfahani, S.1
Kunze, C.A.2
Kulbe, H.3
Sehouli, J.4
Wienert, S.5
Lindner, J.6
-
31
-
-
84938329177
-
PD-L1 and survival in solid tumors: A meta-analysis
-
Wu P, Wu D, Li L, Chai Y, Huang J. PD-L1 and survival in solid tumors: A meta-analysis. PLoS One 2015;10:e0131403.
-
(2015)
PLoS One
, vol.10
, pp. e0131403
-
-
Wu, P.1
Wu, D.2
Li, L.3
Chai, Y.4
Huang, J.5
-
32
-
-
84879795618
-
The presence of programmed death 1 (PD-1)-positive tumor-infiltrating lymphocytes is associated with poor prognosis in human breast cancer
-
Muenst S, Soysal SD, Gao F, Obermann EC, Oertli D, Gillanders WE. The presence of programmed death 1 (PD-1)-positive tumor-infiltrating lymphocytes is associated with poor prognosis in human breast cancer. Breast Cancer Res Treat 2013;139:667-76.
-
(2013)
Breast Cancer Res Treat
, vol.139
, pp. 667-676
-
-
Muenst, S.1
Soysal, S.D.2
Gao, F.3
Obermann, E.C.4
Oertli, D.5
Gillanders, W.E.6
-
33
-
-
34250177269
-
PD-1 is expressed by tumor-infiltrating immune cells and is associated with poor outcome for patients with renal cell carcinoma
-
Thompson RH, Dong H, Lohse CM, Leibovich BC, Blute ML, Cheville JC, et al. PD-1 is expressed by tumor-infiltrating immune cells and is associated with poor outcome for patients with renal cell carcinoma. Clin Cancer Res 2007;13:1757-61.
-
(2007)
Clin Cancer Res
, vol.13
, pp. 1757-1761
-
-
Thompson, R.H.1
Dong, H.2
Lohse, C.M.3
Leibovich, B.C.4
Blute, M.L.5
Cheville, J.C.6
-
34
-
-
84975854490
-
SARC 028: A phase II study of the anti-PD1 antibody pembrolizumab (P) in patients (Pts) with advanced sarcomas
-
abstr TPS10578
-
Burgess MA, Crowley J, Reinke DK, Riedel RF, George S, Movva S, et al. SARC 028: A phase II study of the anti-PD1 antibody pembrolizumab (P) in patients (Pts) with advanced sarcomas. J Clin Oncol 2015;33:abstr TPS10578.
-
(2015)
J Clin Oncol
, pp. 33
-
-
Burgess, M.A.1
Crowley, J.2
Reinke, D.K.3
Riedel, R.F.4
George, S.5
Movva, S.6
-
35
-
-
84936953099
-
Melanoma-intrinsic beta-catenin signalling prevents anti-tumour immunity
-
Spranger S, Bao R, Gajewski TF. Melanoma-intrinsic beta-catenin signalling prevents anti-tumour immunity. Nature 2015;523:231-5.
-
(2015)
Nature
, vol.523
, pp. 231-235
-
-
Spranger, S.1
Bao, R.2
Gajewski, T.F.3
-
37
-
-
84941236554
-
Betacatenin stabilization enhances SS18-SSX2-driven synovial sarcomagenesis and blocks the mesenchymal to epithelial transition
-
Barrott JJ, Illum BE, Jin H, Zhu JF, Mosbruger T, Monument MJ, et al. Betacatenin stabilization enhances SS18-SSX2-driven synovial sarcomagenesis and blocks the mesenchymal to epithelial transition. Oncotarget 2015;6: 22758-66.
-
(2015)
Oncotarget
, vol.6
, pp. 22758-22766
-
-
Barrott, J.J.1
Illum, B.E.2
Jin, H.3
Zhu, J.F.4
Mosbruger, T.5
Monument, M.J.6
-
38
-
-
85028161136
-
SS18-SSX fusion protein-induced Wnt/beta-catenin signaling is a therapeutic target in synovial sarcoma
-
Trautmann M, Sievers E, Aretz S, Kindler D, Michels S, Friedrichs N, et al. SS18-SSX fusion protein-induced Wnt/beta-catenin signaling is a therapeutic target in synovial sarcoma. Oncogene 2014;33:5006-16.
-
(2014)
Oncogene
, vol.33
, pp. 5006-5016
-
-
Trautmann, M.1
Sievers, E.2
Aretz, S.3
Kindler, D.4
Michels, S.5
Friedrichs, N.6
|