-
1
-
-
77954717667
-
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): A randomised, placebo-controlled trial
-
Shakur H, Roberts I, Bautista R, et al. Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial. Lancet 2010; 376: 23-32
-
(2010)
Lancet
, vol.376
, pp. 23-32
-
-
Shakur, H.1
Roberts, I.2
Bautista, R.3
-
2
-
-
85016057559
-
-
World Health Organization (WHO) 63rd World Health Assembly accessed 15 February
-
World Health Organization (WHO) 63rd World Health Assembly. Availability, safety and quality of blood. Available from http://apps.who.int/gb/ebwha/pdf-files/WHA63/A63- R12-en.pdf.2010 (accessed 15 February 2016)
-
(2016)
Availability, Safety and Quality of Blood
-
-
-
3
-
-
84879173771
-
Management of severe perioperative bleeding: Guidelines from the European Society of Anaesthesiology
-
Kozek-Langenecker SA, Afshari A, Albaladejo P, et al. Management of severe perioperative bleeding: guidelines from the European Society of Anaesthesiology. Eur J Anaesthesiol 2013; 30: 270-382
-
(2013)
Eur J Anaesthesiol
, vol.30
, pp. 270-382
-
-
Kozek-Langenecker, S.A.1
Afshari, A.2
Albaladejo, P.3
-
4
-
-
84925348610
-
Practice guidelines for perioperative blood management: An updated report by the American Society of Anesthesiologists Task Force on Perioperative Blood Management
-
American Society of Anesthesiologists Task Force on Perioperative Blood Management
-
American Society of Anesthesiologists Task Force on Perioperative Blood Management. Practice guidelines for perioperative blood management: an updated report by the American Society of Anesthesiologists Task Force on Perioperative Blood Management. Anesthesiology 2015; 122: 241-75
-
(2015)
Anesthesiology
, vol.122
, pp. 241-275
-
-
-
5
-
-
84888228700
-
Antifibrinolytic agents in current anaesthetic practice
-
Ortmann E, Besser MW, Klein AA. Antifibrinolytic agents in current anaesthetic practice. Br J Anaesth 2013; 111: 549-63
-
(2013)
Br J Anaesth
, vol.111
, pp. 549-563
-
-
Ortmann, E.1
Besser, M.W.2
Klein, A.A.3
-
6
-
-
58949085197
-
Efficacy and safety of prophylactic large dose of tranexamic acid in spine surgery: A prospective, randomized, double-blind, placebo-controlled study
-
Elwatidy S, Jamjoom Z, Elgamal E, Zakaria A, Turkistani A, El-Dawlatly A. Efficacy and safety of prophylactic large dose of tranexamic acid in spine surgery: a prospective, randomized, double-blind, placebo-controlled study. Spine (Phila Pa 1976) 2008; 33: 2577-80
-
(2008)
Spine (Phila Pa 1976)
, vol.33
, pp. 2577-2580
-
-
Elwatidy, S.1
Jamjoom, Z.2
Elgamal, E.3
Zakaria, A.4
Turkistani, A.5
El-Dawlatly, A.6
-
7
-
-
80054900218
-
Tranexamic acid reduces perioperative blood loss in cervical laminoplasty: A prospective randomized study
-
Tsutsumimoto T, Shimogata M, Ohta H, Yui M, Yoda I, Misawa H. Tranexamic acid reduces perioperative blood loss in cervical laminoplasty: a prospective randomized study. Spine (Phila Pa 1976) 2011; 36: 1913-8
-
(2011)
Spine (Phila Pa 1976)
, vol.36
, pp. 1913-1918
-
-
Tsutsumimoto, T.1
Shimogata, M.2
Ohta, H.3
Yui, M.4
Yoda, I.5
Misawa, H.6
-
8
-
-
81155161048
-
Efficacy of prophylactic low dose of tranexamic acid in spinal fixation surgery: A randomized clinical trial
-
Farrokhi MR, Kazemi AP, Eftekharian HR, Akbari K. Efficacy of prophylactic low dose of tranexamic acid in spinal fixation surgery: a randomized clinical trial. J Neurosurg Anesthesiol 2011; 23: 290-6
-
(2011)
J Neurosurg Anesthesiol
, vol.23
, pp. 290-296
-
-
Farrokhi, M.R.1
Kazemi, A.P.2
Eftekharian, H.R.3
Akbari, K.4
-
9
-
-
84885297706
-
Tranexamic acid reduces postoperative blood loss of degenerative lumbar instability with stenosis in posterior approach lumbar surgery: A randomized controlled trial
-
Wang Q, Liu J, Fan R, et al. Tranexamic acid reduces postoperative blood loss of degenerative lumbar instability with stenosis in posterior approach lumbar surgery: a randomized controlled trial. Eur Spine J 2013; 22: 2035-8
-
(2013)
Eur Spine J
, vol.22
, pp. 2035-2038
-
-
Wang, Q.1
Liu, J.2
Fan, R.3
-
10
-
-
84901333771
-
The relative efficacy of antifibrinolytics in adolescent idiopathic scoliosis: A prospective randomized trial
-
Verma K, Errico T, Diefenbach C, et al. The relative efficacy of antifibrinolytics in adolescent idiopathic scoliosis: a prospective randomized trial. J Bone Joint Surg Am 2014; 96: e80.
-
(2014)
J Bone Joint Surg Am
, vol.96
, pp. e80
-
-
Verma, K.1
Errico, T.2
Diefenbach, C.3
-
11
-
-
84958178049
-
Antifibrinolytics reduce blood loss in adult spinal deformity surgery: A prospective, randomized controlled trial
-
Peters A, Verma K, Slobodyanyuk K, et al. Antifibrinolytics reduce blood loss in adult spinal deformity surgery: a prospective, randomized controlled trial. Spine (Phila Pa 1976) 2015; 40: E443-9
-
(2015)
Spine (Phila Pa 1976)
, vol.40
, pp. E443-E449
-
-
Peters, A.1
Verma, K.2
Slobodyanyuk, K.3
-
12
-
-
85016067386
-
Efficacy of antifibrinolytic agents on surgical bleeding and transfusion requirements in spine surgery: A meta-analysis
-
Advance Access published on September 26
-
Li G, Sun TW, Luo G, Zhang C. Efficacy of antifibrinolytic agents on surgical bleeding and transfusion requirements in spine surgery: a meta-analysis. Eur Spine J. Advance Access published on September 26, 2016
-
(2016)
Eur Spine J
-
-
Li, G.1
Sun, T.W.2
Luo, G.3
Zhang, C.4
-
13
-
-
84956574965
-
Tranexamic acid-associated seizures: Causes and treatment
-
Lecker I, Wang DS, Whissell PD, Avramescu S, Mazer CD, Orser BA. Tranexamic acid-associated seizures: causes and treatment. Ann Neurol 2016; 79: 18-26
-
(2016)
Ann Neurol
, vol.79
, pp. 18-26
-
-
Lecker, I.1
Wang, D.S.2
Whissell, P.D.3
Avramescu, S.4
Mazer, C.D.5
Orser, B.A.6
-
14
-
-
84055192250
-
High-dose tranexamic acid is an independent predictor of early seizure after cardiopulmonary bypass
-
Kalavrouziotis D, Voisine P, Mohammadi S, Dionne S, Dagenais F. High-dose tranexamic acid is an independent predictor of early seizure after cardiopulmonary bypass. Ann Thorac Surg 2012; 93: 148-54
-
(2012)
Ann Thorac Surg
, vol.93
, pp. 148-154
-
-
Kalavrouziotis, D.1
Voisine, P.2
Mohammadi, S.3
Dionne, S.4
Dagenais, F.5
-
15
-
-
85015997873
-
Safety of antifibrinolytics in cranial vault reconstructive surgery: A report from the pediatric craniofacial collaborative group
-
In Print
-
Goobie SM, Cladis FP, G CD, Huang H, Reddy SK, Fernandez A, et al. Safety of antifibrinolytics in cranial vault reconstructive surgery: a report from the pediatric craniofacial collaborative group. Paediatr Anaesth 2016; In Print
-
(2016)
Paediatr Anaesth
-
-
Goobie, S.M.1
Cladis, F.P.2
Cd, D.3
Huang, H.4
Reddy, S.K.5
Fernandez, A.6
-
16
-
-
84870526551
-
Tranexamic acid concentrations associated with human seizures inhibit glycine receptors
-
Lecker I, Wang DS, Romaschin AD, Peterson M, Mazer CD, Orser BA. Tranexamic acid concentrations associated with human seizures inhibit glycine receptors. J Clin Invest 2012; 122: 4654-66
-
(2012)
J Clin Invest
, vol.122
, pp. 4654-4666
-
-
Lecker, I.1
Wang, D.S.2
Romaschin, A.D.3
Peterson, M.4
Mazer, C.D.5
Orser, B.A.6
-
17
-
-
84895486195
-
Tranexamic acid impairs gamma-aminobutyric acid receptor type A-mediated synaptic transmission in the murine amygdala: A potential mechanism for drug-induced seizures?
-
Kratzer S, Irl H, Mattusch C, et al. Tranexamic acid impairs gamma-aminobutyric acid receptor type A-mediated synaptic transmission in the murine amygdala: a potential mechanism for drug-induced seizures? Anesthesiology 2014; 120: 639-49
-
(2014)
Anesthesiology
, vol.120
, pp. 639-649
-
-
Kratzer, S.1
Irl, H.2
Mattusch, C.3
-
18
-
-
84907359498
-
Tranexamic acid use and postoperative outcomes in patients undergoing total hip or knee arthroplasty in the United States: Retrospective analysis of effectiveness and safety
-
Poeran J, Rasul R, Suzuki S, et al. Tranexamic acid use and postoperative outcomes in patients undergoing total hip or knee arthroplasty in the United States: retrospective analysis of effectiveness and safety. Br Med J 2014; 349: g4829
-
(2014)
Br Med J
, vol.349
, pp. g4829
-
-
Poeran, J.1
Rasul, R.2
Suzuki, S.3
-
19
-
-
79952270874
-
Anti-fibrinolytic use for minimising perioperative allogeneic blood transfusion
-
Mar 16(3)
-
Henry DA, Carless PA, Moxey AJ, O'Connell D, Stokes BJ, Fergusson DA, et al. Anti-fibrinolytic use for minimising perioperative allogeneic blood transfusion. Cochrane Database Syst Rev 2011; Mar 16(3): doi: 10.1002/14651858. CD001886.pub4
-
(2011)
Cochrane Database Syst Rev
-
-
Henry, D.A.1
Carless, P.A.2
Moxey, A.J.3
O'Connell, D.4
Stokes, B.J.5
Fergusson, D.A.6
-
22
-
-
84894664135
-
The efficacy of antifibrinolytic drugs in children undergoing noncardiac surgery: A systematic review of the literature
-
Faraoni D, Goobie SM. The efficacy of antifibrinolytic drugs in children undergoing noncardiac surgery: a systematic review of the literature. Anesth Analg 2014; 118: 628-36
-
(2014)
Anesth Analg
, vol.118
, pp. 628-636
-
-
Faraoni, D.1
Goobie, S.M.2
-
23
-
-
84976439841
-
Effect of antifibrinolytic therapy on complications, thromboembolic events, blood product utilization, and fusion in adult spinal deformity surgery
-
Soroceanu A, Oren JH, Smith JS, et al. Effect of antifibrinolytic therapy on complications, thromboembolic events, blood product utilization, and fusion in adult spinal deformity surgery. Spine (Phila Pa 1976) 2016; 41: E879-86
-
(2016)
Spine (Phila Pa 1976)
, vol.41
, pp. E879-E886
-
-
Soroceanu, A.1
Oren, J.H.2
Smith, J.S.3
-
24
-
-
85033717211
-
High-dose versus low-dose Tranexamic acid to reduce transfusion requirements in pediatric scoliosis surgery
-
Advance Access published on June 27
-
Johnson DJ, Johnson CC, Goobie S, Nami N, Wetzler JA, Sponseller PD, Frank SM. High-dose versus low-dose Tranexamic acid to reduce transfusion requirements in pediatric scoliosis surgery. J Pediatr Orthop. Advance Access published on June 27, 2016, doi: 10.1097/BPO.00000 00000000820
-
(2016)
J Pediatr Orthop
-
-
Johnson, D.J.1
Johnson, C.C.2
Goobie, S.3
Nami, N.4
Wetzler, J.A.5
Sponseller, P.D.6
Frank, S.M.7
-
25
-
-
84932082279
-
Pharmacokinetics of tranexamic acid in neonates, infants, and children undergoing cardiac surgery with cardiopulmonary bypass
-
Wesley MC, Pereira LM, Scharp LA, Emani SM, McGowan FX Jr, DiNardo JA. Pharmacokinetics of tranexamic acid in neonates, infants, and children undergoing cardiac surgery with cardiopulmonary bypass. Anesthesiology 2015; 122: 746-58
-
(2015)
Anesthesiology
, vol.122
, pp. 746-758
-
-
Wesley, M.C.1
Pereira, L.M.2
Scharp, L.A.3
Emani, S.M.4
McGowan, F.X.5
DiNardo, J.A.6
-
26
-
-
0014432942
-
Role of urokinase and tissue activator in sustaining bleeding and the management thereof with EACA and AMCA
-
Andersson L, Nilsoon IM, Colleen S, Granstrand B, Melander B. Role of urokinase and tissue activator in sustaining bleeding and the management thereof with EACA and AMCA. Ann N Y Acad Sci 1968; 146: 642-58
-
(1968)
Ann N y Acad Sci
, vol.146
, pp. 642-658
-
-
Andersson, L.1
Nilsoon, I.M.2
Colleen, S.3
Granstrand, B.4
Melander, B.5
-
27
-
-
0036321694
-
Pharmacokinetics of tranexamic acid during cardiopulmonary bypass
-
Dowd NP, Karski JM, Cheng DC, et al. Pharmacokinetics of tranexamic acid during cardiopulmonary bypass. Anesthesiology 2002; 97: 390-9
-
(2002)
Anesthesiology
, vol.97
, pp. 390-399
-
-
Dowd, N.P.1
Karski, J.M.2
Cheng, D.C.3
-
28
-
-
84885017495
-
New insights about the use of tranexamic acid in children undergoing cardiac surgery: From pharmacokinetics to pharmacodynamics
-
Faraoni D, Goobie SM. New insights about the use of tranexamic acid in children undergoing cardiac surgery: from pharmacokinetics to pharmacodynamics. Anesthesia and Analgesia 2013; 117: 760-2
-
(2013)
Anesthesia and Analgesia
, vol.117
, pp. 760-762
-
-
Faraoni, D.1
Goobie, S.M.2
-
29
-
-
84907972088
-
Recent advances on plasmin inhibitors for the treatment of fibrinolysis-related disorders
-
Al-Horani RA, Desai UR. Recent advances on plasmin inhibitors for the treatment of fibrinolysis-related disorders. Med Res Rev 2014; 34: 1168-216
-
(2014)
Med Res Rev
, vol.34
, pp. 1168-1216
-
-
Al-Horani, R.A.1
Desai, U.R.2
-
31
-
-
85016158687
-
Systemic and topical use of tranexamic acid in spinal surgery: A systematic review
-
Winter SF, Santaguida C, Wong J, Fehlings MG. Systemic and topical use of tranexamic acid in spinal surgery: a systematic review. Global Spine J 2016; 6: 284-95
-
(2016)
Global Spine J
, vol.6
, pp. 284-295
-
-
Winter, S.F.1
Santaguida, C.2
Wong, J.3
Fehlings, M.G.4
-
32
-
-
41149083908
-
Postoperative bleeding in cardiac surgery: The role of tranexamic acid in patients homozygous for the 5G polymorphism of the plasminogen activator inhibitor-1 gene
-
Iribarren JL, Jimenez JJ, Hernandez D, et al. Postoperative bleeding in cardiac surgery: the role of tranexamic acid in patients homozygous for the 5G polymorphism of the plasminogen activator inhibitor-1 gene. Anesthesiology 2008; 108: 596-602
-
(2008)
Anesthesiology
, vol.108
, pp. 596-602
-
-
Iribarren, J.L.1
Jimenez, J.J.2
Hernandez, D.3
|