메뉴 건너뛰기




Volumn 77, Issue 6, 2017, Pages 1331-1344

Bone metastasis of prostate cancer can be therapeutically targeted at the TBX2-WNT signaling axis

Author keywords

[No Author keywords available]

Indexed keywords

NEUTRALIZING ANTIBODY; SECRETED FRIZZLED RELATED PROTEIN 2; TRANSCRIPTION FACTOR T BET; WNT3A PROTEIN; MONOCLONAL ANTIBODY; T BOX TRANSCRIPTION FACTOR; T-BOX DOMAIN PROTEIN 2; TUMOR MARKER; WNT3A PROTEIN, HUMAN;

EID: 85015925007     PISSN: 00085472     EISSN: 15387445     Source Type: Journal    
DOI: 10.1158/0008-5472.CAN-16-0497     Document Type: Article
Times cited : (55)

References (50)
  • 1
    • 84856223934 scopus 로고    scopus 로고
    • Dynamic expression of Tbx2 subfamily genes in development of the mouse reproductive system
    • Douglas NC, Heng K, Sauer MV, Papaioannou VE. Dynamic expression of Tbx2 subfamily genes in development of the mouse reproductive system. Dev Dyn 2012;241: 365-75.
    • (2012) Dev Dyn , vol.241 , pp. 365-375
    • Douglas, N.C.1    Heng, K.2    Sauer, M.V.3    Papaioannou, V.E.4
  • 2
    • 79959949912 scopus 로고    scopus 로고
    • Mechanisms of T-box gene function in the developing heart
    • Greulich F, Rudat C, Kispert A. Mechanisms of T-box gene function in the developing heart. Cardiovasc Res 2011;91: 212-22.
    • (2011) Cardiovasc Res , vol.91 , pp. 212-222
    • Greulich, F.1    Rudat, C.2    Kispert, A.3
  • 3
    • 78751528579 scopus 로고    scopus 로고
    • Role of Tbx2 in defining the territory of the pronephric nephron
    • Cho GS, Choi SC, Park EC, Han JK. Role of Tbx2 in defining the territory of the pronephric nephron. Development 2011;138: 465-74.
    • (2011) Development , vol.138 , pp. 465-474
    • Cho, G.S.1    Choi, S.C.2    Park, E.C.3    Han, J.K.4
  • 4
    • 0033764030 scopus 로고    scopus 로고
    • Senescence bypass screen identifies TBX2, which represses Cdkn2a (p19(ARF)) and is amplified in a subset of human breast cancers
    • Jacobs JJ, Keblusek P, Robanus-Maandag E, Kristel P, Lingbeek M, Nederlof PM, et al. Senescence bypass screen identifies TBX2, which represses Cdkn2a (p19(ARF)) and is amplified in a subset of human breast cancers. Nat Genet 2000;26: 291-9.
    • (2000) Nat Genet , vol.26 , pp. 291-299
    • Jacobs, J.J.1    Keblusek, P.2    Robanus-Maandag, E.3    Kristel, P.4    Lingbeek, M.5    Nederlof, P.M.6
  • 5
    • 0037135545 scopus 로고    scopus 로고
    • The T-box repressors TBX2 and TBX3 specifically regulate the tumor suppressor gene p14ARF via a variant T-site in the initiator
    • Lingbeek ME, Jacobs JJ, van Lohuizen M. The T-box repressors TBX2 and TBX3 specifically regulate the tumor suppressor gene p14ARF via a variant T-site in the initiator. J Biol Chem 2002;277: 26120-7.
    • (2002) J Biol Chem , vol.277 , pp. 26120-26127
    • Lingbeek, M.E.1    Jacobs, J.J.2    Van Lohuizen, M.3
  • 6
    • 16844387097 scopus 로고    scopus 로고
    • Tbx2 is overexpressed and plays an important role in maintaining proliferation and suppression of senescence in melanomas
    • Vance KW, Carreira S, Brosch G, Goding CR. Tbx2 is overexpressed and plays an important role in maintaining proliferation and suppression of senescence in melanomas. Cancer Res 2005;65: 2260-8.
    • (2005) Cancer Res , vol.65 , pp. 2260-2268
    • Vance, K.W.1    Carreira, S.2    Brosch, G.3    Goding, C.R.4
  • 8
    • 0036317876 scopus 로고    scopus 로고
    • High-throughput copy number analysis of 17q23 in 3520 tissue specimens by fluorescence in situ hybridization to tissue microarrays
    • Andersen CL, Monni O, Wagner U, Kononen J, Barlund M, Bucher C, et al. High-throughput copy number analysis of 17q23 in 3520 tissue specimens by fluorescence in situ hybridization to tissue microarrays. Am J Pathol 2002;161: 73-9.
    • (2002) Am J Pathol , vol.161 , pp. 73-79
    • Andersen, C.L.1    Monni, O.2    Wagner, U.3    Kononen, J.4    Barlund, M.5    Bucher, C.6
  • 9
    • 0028272478 scopus 로고
    • Androgen-independent cancer progression and bone metastasis in the LNCaP model of human prostate cancer
    • Thalmann GN, Anezinis PE, Chang SM, Zhau HE, Kim EE, Hopwood VL, et al. Androgen-independent cancer progression and bone metastasis in the LNCaP model of human prostate cancer. Cancer Res 1994;54: 2577-81.
    • (1994) Cancer Res , vol.54 , pp. 2577-2581
    • Thalmann, G.N.1    Anezinis, P.E.2    Chang, S.M.3    Zhau, H.E.4    Kim, E.E.5    Hopwood, V.L.6
  • 11
    • 33750466563 scopus 로고    scopus 로고
    • Prostate cancer metastasis: Role of the host microenvironment in promoting epithelial to mesenchymal transition and increased bone and adrenal gland metastasis
    • Xu J, Wang R, Xie ZH, Odero-Marah V, Pathak S, Multani A, et al. Prostate cancer metastasis: Role of the host microenvironment in promoting epithelial to mesenchymal transition and increased bone and adrenal gland metastasis. Prostate 2006;66: 1664-73.
    • (2006) Prostate , vol.66 , pp. 1664-1673
    • Xu, J.1    Wang, R.2    Xie, Z.H.3    Odero-Marah, V.4    Pathak, S.5    Multani, A.6
  • 12
    • 47549095025 scopus 로고    scopus 로고
    • Epithelial to mesenchymal transition (EMT) in human prostate cancer: Lessons learned from ARCaP model
    • Zhau HE, Odero-Marah V, Lue HW, Nomura T, Wang R, Chu G, et al. Epithelial to mesenchymal transition (EMT) in human prostate cancer: Lessons learned from ARCaP model. Clin Exp Metastasis 2008;25: 601-10.
    • (2008) Clin Exp Metastasis , vol.25 , pp. 601-610
    • Zhau, H.E.1    Odero-Marah, V.2    Lue, H.W.3    Nomura, T.4    Wang, R.5    Chu, G.6
  • 13
    • 0033119141 scopus 로고    scopus 로고
    • E-cadherin expression as a marker of tumor aggressiveness in routinely processed radical prostatectomy specimens
    • De Marzo AM, Knudsen B, Chan-Tack K, Epstein JI. E-cadherin expression as a marker of tumor aggressiveness in routinely processed radical prostatectomy specimens. Urology 1999;53: 707-13.
    • (1999) Urology , vol.53 , pp. 707-713
    • De Marzo, A.M.1    Knudsen, B.2    Chan-Tack, K.3    Epstein, J.I.4
  • 14
    • 0031849770 scopus 로고    scopus 로고
    • Establishing human prostate cancer cell xenografts in bone: Induction of osteoblastic reaction by prostate-specific antigen-producing tumors in athymic and SCID/bg mice using LNCaP and lineage-derived metastatic sublines
    • Wu TT, Sikes RA, Cui Q, Thalmann GN, Kao C, Murphy CF, et al. Establishing human prostate cancer cell xenografts in bone: Induction of osteoblastic reaction by prostate-specific antigen-producing tumors in athymic and SCID/bg mice using LNCaP and lineage-derived metastatic sublines. Int J Cancer 1998;77: 887-94.
    • (1998) Int J Cancer , vol.77 , pp. 887-894
    • Wu, T.T.1    Sikes, R.A.2    Cui, Q.3    Thalmann, G.N.4    Kao, C.5    Murphy, C.F.6
  • 15
    • 84899864278 scopus 로고    scopus 로고
    • RANKand c-Met-mediated signal network promotes prostate cancer metastatic colonization
    • Chu GC, Zhau HE, Wang R, Rogatko A, Feng X, Zayzafoon M, et al. RANKand c-Met-mediated signal network promotes prostate cancer metastatic colonization. Endocr Relat Cancer 2014;21: 311-26.
    • (2014) Endocr Relat Cancer , vol.21 , pp. 311-326
    • Chu, G.C.1    Zhau, H.E.2    Wang, R.3    Rogatko, A.4    Feng, X.5    Zayzafoon, M.6
  • 16
    • 49149114127 scopus 로고    scopus 로고
    • Receptor activator of NF-kappaB Ligand (RANKL) expression is associated with epithelial to mesenchymal transition in human prostate cancer cells
    • Odero-Marah VA, Wang R, Chu G, Zayzafoon M, Xu J, Shi C, et al. Receptor activator of NF-kappaB Ligand (RANKL) expression is associated with epithelial to mesenchymal transition in human prostate cancer cells. Cell Res 2008;18: 858-70.
    • (2008) Cell Res , vol.18 , pp. 858-870
    • Odero-Marah, V.A.1    Wang, R.2    Chu, G.3    Zayzafoon, M.4    Xu, J.5    Shi, C.6
  • 17
    • 27344451557 scopus 로고    scopus 로고
    • Recurrent fusion of TMPRSS2 and ETS transcription factor genes in prostate cancer
    • Tomlins SA, Rhodes DR, Perner S, Dhanasekaran SM, Mehra R, Sun XW, et al. Recurrent fusion of TMPRSS2 and ETS transcription factor genes in prostate cancer. Science 2005;310: 644-8.
    • (2005) Science , vol.310 , pp. 644-648
    • Tomlins, S.A.1    Rhodes, D.R.2    Perner, S.3    Dhanasekaran, S.M.4    Mehra, R.5    Sun, X.W.6
  • 18
    • 48749092646 scopus 로고    scopus 로고
    • Androgen receptor-negative human prostate cancer cells induce osteogenesis in mice through FGF9-mediated mechanisms
    • Li ZG, Mathew P, Yang J, StarbuckMW, Zurita AJ, Liu J, et al. Androgen receptor-negative human prostate cancer cells induce osteogenesis in mice through FGF9-mediated mechanisms. J Clin Invest 2008;118: 2697-710.
    • (2008) J Clin Invest , vol.118 , pp. 2697-2710
    • Li, Z.G.1    Mathew, P.2    Yang, J.3    Starbuck, M.W.4    Zurita, A.J.5    Liu, J.6
  • 19
    • 0035504693 scopus 로고    scopus 로고
    • A dominant repression domain in Tbx3 mediates transcriptional repression and cell immortalization: Relevance to mutations in Tbx3 that cause ulnar-mammary syndrome
    • Carlson H, Ota S, Campbell CE, Hurlin PJ. A dominant repression domain in Tbx3 mediates transcriptional repression and cell immortalization: Relevance to mutations in Tbx3 that cause ulnar-mammary syndrome. Hum Mol Genet 2001;10: 2403-13.
    • (2001) Hum Mol Genet , vol.10 , pp. 2403-2413
    • Carlson, H.1    Ota, S.2    Campbell, C.E.3    Hurlin, P.J.4
  • 21
    • 0030223057 scopus 로고    scopus 로고
    • Selection of highly metastatic variants of different human prostatic carcinomas using orthotopic implantation in nude mice
    • Pettaway CA, Pathak S, Greene G, Ramirez E, Wilson MR, Killion JJ, et al. Selection of highly metastatic variants of different human prostatic carcinomas using orthotopic implantation in nude mice. Clin Cancer Res 1996;2: 1627-36.
    • (1996) Clin Cancer Res , vol.2 , pp. 1627-1636
    • Pettaway, C.A.1    Pathak, S.2    Greene, G.3    Ramirez, E.4    Wilson, M.R.5    Killion, J.J.6
  • 23
    • 0033895499 scopus 로고    scopus 로고
    • Suppression of primary tumor growth and the progression to metastasis with p53 adenovirus in human prostate cancer
    • Eastham JA, Grafton W, Martin CM, Williams BJ. Suppression of primary tumor growth and the progression to metastasis with p53 adenovirus in human prostate cancer. J Urol 2000;164: 814-9.
    • (2000) J Urol , vol.164 , pp. 814-819
    • Eastham, J.A.1    Grafton, W.2    Martin, C.M.3    Williams, B.J.4
  • 24
    • 0033962103 scopus 로고    scopus 로고
    • Markers of bone turnover for the management of patients with bone metastases from prostate cancer
    • Garnero P, Buchs N, Zekri J, Rizzoli R, Coleman RE, Delmas PD. Markers of bone turnover for the management of patients with bone metastases from prostate cancer. Br J Cancer 2000;82: 858-64.
    • (2000) Br J Cancer , vol.82 , pp. 858-864
    • Garnero, P.1    Buchs, N.2    Zekri, J.3    Rizzoli, R.4    Coleman, R.E.5    Delmas, P.D.6
  • 25
    • 21044447090 scopus 로고    scopus 로고
    • Prostate cancer mediates osteoclastogenesis through two different pathways
    • Inoue H, Nishimura K, Oka D, Nakai Y, Shiba M, Tokizane T, et al. Prostate cancer mediates osteoclastogenesis through two different pathways. Cancer Lett 2005;223: 121-8.
    • (2005) Cancer Lett , vol.223 , pp. 121-128
    • Inoue, H.1    Nishimura, K.2    Oka, D.3    Nakai, Y.4    Shiba, M.5    Tokizane, T.6
  • 26
    • 0035021176 scopus 로고    scopus 로고
    • Osteoprotegerin inhibits prostate cancer-induced osteoclastogenesis and prevents prostate tumor growth in the bone
    • Zhang J, Dai J, Qi Y, Lin DL, Smith P, Strayhorn C, et al. Osteoprotegerin inhibits prostate cancer-induced osteoclastogenesis and prevents prostate tumor growth in the bone. J Clin Invest 2001;107: 1235-44.
    • (2001) J Clin Invest , vol.107 , pp. 1235-1244
    • Zhang, J.1    Dai, J.2    Qi, Y.3    Lin, D.L.4    Smith, P.5    Strayhorn, C.6
  • 27
    • 33847729474 scopus 로고    scopus 로고
    • DU145 human prostate cancer cells express functional receptor activator of NFkappaB: New insights in the prostate cancer bone metastasis process
    • Mori K, Le Goff B, Charrier C, Battaglia S, Heymann D, Redini F. DU145 human prostate cancer cells express functional receptor activator of NFkappaB: New insights in the prostate cancer bone metastasis process. Bone 2007;40: 981-90.
    • (2007) Bone , vol.40 , pp. 981-990
    • Mori, K.1    Le Goff, B.2    Charrier, C.3    Battaglia, S.4    Heymann, D.5    Redini, F.6
  • 28
    • 1542317670 scopus 로고    scopus 로고
    • Intraosseous growth of human prostate cancer in implanted adult human bone: Relationship of prostate cancer cells to osteoclasts in osteoblastic metastatic lesions
    • Yonou H, Ochiai A, Goya M, Kanomata N, Hokama S, Morozumi M, et al. Intraosseous growth of human prostate cancer in implanted adult human bone: Relationship of prostate cancer cells to osteoclasts in osteoblastic metastatic lesions. Prostate 2004;58: 406-13.
    • (2004) Prostate , vol.58 , pp. 406-413
    • Yonou, H.1    Ochiai, A.2    Goya, M.3    Kanomata, N.4    Hokama, S.5    Morozumi, M.6
  • 29
    • 7444256731 scopus 로고    scopus 로고
    • Analysis of Wnt gene expression in prostate cancer: Mutual inhibition by WNT11 and the androgen receptor
    • Zhu H, Mazor M, Kawano Y, Walker MM, Leung HY, Armstrong K, et al. Analysis of Wnt gene expression in prostate cancer: Mutual inhibition by WNT11 and the androgen receptor. Cancer Res 2004;64: 7918-26.
    • (2004) Cancer Res , vol.64 , pp. 7918-7926
    • Zhu, H.1    Mazor, M.2    Kawano, Y.3    Walker, M.M.4    Leung, H.Y.5    Armstrong, K.6
  • 31
    • 79954461450 scopus 로고    scopus 로고
    • Expression profile of WNT molecules in prostate cancer and its regulation by aminobisphosphonates
    • Thiele S, Rauner M, Goettsch C, Rachner TD, Benad P, Fuessel S, et al. Expression profile of WNT molecules in prostate cancer and its regulation by aminobisphosphonates. J Cell Biochem 2011;112: 1593-600.
    • (2011) J Cell Biochem , vol.112 , pp. 1593-1600
    • Thiele, S.1    Rauner, M.2    Goettsch, C.3    Rachner, T.D.4    Benad, P.5    Fuessel, S.6
  • 32
    • 33646533771 scopus 로고    scopus 로고
    • Roles and regulation of Wnt signaling and beta-catenin in prostate cancer
    • Verras M, Sun Z. Roles and regulation of Wnt signaling and beta-catenin in prostate cancer. Cancer Lett 2006;237: 22-32.
    • (2006) Cancer Lett , vol.237 , pp. 22-32
    • Verras, M.1    Sun, Z.2
  • 34
    • 79955479314 scopus 로고    scopus 로고
    • Wnt/beta-catenin activation promotes prostate tumor progression in a mouse model
    • Yu X, Wang Y, DeGraff DJ, Wills ML, Matusik RJ. Wnt/beta-catenin activation promotes prostate tumor progression in a mouse model. Oncogene 2011;30: 1868-79.
    • (2011) Oncogene , vol.30 , pp. 1868-1879
    • Yu, X.1    Wang, Y.2    DeGraff, D.J.3    Wills, M.L.4    Matusik, R.J.5
  • 35
    • 67649948804 scopus 로고    scopus 로고
    • WNT signaling regulates self-renewal and differentiation of prostate cancer cells with stem cell characteristics
    • Bisson I, Prowse DM. WNT signaling regulates self-renewal and differentiation of prostate cancer cells with stem cell characteristics. Cell Res 2009;19: 683-97.
    • (2009) Cell Res , vol.19 , pp. 683-697
    • Bisson, I.1    Prowse, D.M.2
  • 37
    • 24744439747 scopus 로고    scopus 로고
    • Prostate cancer cells promote osteoblastic bone metastases through Wnts
    • Hall CL, Bafico A, Dai J, Aaronson SA, Keller ET. Prostate cancer cells promote osteoblastic bone metastases through Wnts. Cancer Res 2005; 65: 7554-60.
    • (2005) Cancer Res , vol.65 , pp. 7554-7560
    • Hall, C.L.1    Bafico, A.2    Dai, J.3    Aaronson, S.A.4    Keller, E.T.5
  • 38
    • 48649090754 scopus 로고    scopus 로고
    • Prostate cancer induces bone metastasis through Wnt-induced bone morphogenetic protein-dependent and independent mechanisms
    • Dai J, Hall CL, Escara-Wilke J, Mizokami A, Keller JM, Keller ET. Prostate cancer induces bone metastasis through Wnt-induced bone morphogenetic protein-dependent and independent mechanisms. Cancer Res 2008;68: 5785-94.
    • (2008) Cancer Res , vol.68 , pp. 5785-5794
    • Dai, J.1    Hall, C.L.2    Escara-Wilke, J.3    Mizokami, A.4    Keller, J.M.5    Keller, E.T.6
  • 41
    • 84883190661 scopus 로고    scopus 로고
    • WNT/beta-catenin signaling induces IL-1beta expression by alveolar epithelial cells in pulmonary fibrosis
    • Aumiller V, Balsara N, Wilhelm J, Gunther A, Konigshoff M. WNT/beta-catenin signaling induces IL-1beta expression by alveolar epithelial cells in pulmonary fibrosis. Am J Respir Cell Mol Biol 2013; 49: 96-104.
    • (2013) Am J Respir Cell Mol Biol , vol.49 , pp. 96-104
    • Aumiller, V.1    Balsara, N.2    Wilhelm, J.3    Gunther, A.4    Konigshoff, M.5
  • 42
    • 16344365813 scopus 로고    scopus 로고
    • The prognostic significance of plasma interleukin-6 levels in patients with metastatic hormone-refractory prostate cancer: Results from cancer and leukemia group B 9480
    • George DJ, Halabi S, Shepard TF, Sanford B, Vogelzang NJ, Small EJ, et al. The prognostic significance of plasma interleukin-6 levels in patients with metastatic hormone-refractory prostate cancer: Results from cancer and leukemia group B 9480. Clin Cancer Res 2005;11: 1815-20.
    • (2005) Clin Cancer Res , vol.11 , pp. 1815-1820
    • George, D.J.1    Halabi, S.2    Shepard, T.F.3    Sanford, B.4    Vogelzang, N.J.5    Small, E.J.6
  • 44
    • 33847268280 scopus 로고    scopus 로고
    • Wnt signaling induces matrix metalloproteinase expression and regulates T cell transmigration
    • Wu B, Crampton SP, Hughes CC. Wnt signaling induces matrix metalloproteinase expression and regulates T cell transmigration. Immunity 2007;26: 227-39.
    • (2007) Immunity , vol.26 , pp. 227-239
    • Wu, B.1    Crampton, S.P.2    Hughes, C.C.3
  • 45
    • 0037005993 scopus 로고    scopus 로고
    • Matrix metalloproteinase activity, bone matrix turnover, and tumor cell proliferation in prostate cancer bone metastasis
    • Nemeth JA, Yousif R, Herzog M, Che M, Upadhyay J, Shekarriz B, et al. Matrix metalloproteinase activity, bone matrix turnover, and tumor cell proliferation in prostate cancer bone metastasis. J Natl Cancer Inst 2002;94: 17-25.
    • (2002) J Natl Cancer Inst , vol.94 , pp. 17-25
    • Nemeth, J.A.1    Yousif, R.2    Herzog, M.3    Che, M.4    Upadhyay, J.5    Shekarriz, B.6
  • 46
    • 0032548966 scopus 로고    scopus 로고
    • Serum matrix metalloproteinase-2 and its density in men with prostate cancer as a new predictor of disease extension
    • Gohji K, Fujimoto N, Hara I, Fujii A, Gotoh A, Okada H, et al. Serum matrix metalloproteinase-2 and its density in men with prostate cancer as a new predictor of disease extension. Int J Cancer 1998; 79: 96-101.
    • (1998) Int J Cancer , vol.79 , pp. 96-101
    • Gohji, K.1    Fujimoto, N.2    Hara, I.3    Fujii, A.4    Gotoh, A.5    Okada, H.6
  • 48
    • 0033567964 scopus 로고    scopus 로고
    • Interleukin-6 regulation of matrix metalloproteinase (MMP-2 and MMP-9) and tissue inhibitor of metalloproteinase (TIMP-1) expression in malignant non-Hodgkin's lymphomas
    • Kossakowska AE, Edwards DR, Prusinkiewicz C, Zhang MC, Guo D, Urbanski SJ, et al. Interleukin-6 regulation of matrix metalloproteinase (MMP-2 and MMP-9) and tissue inhibitor of metalloproteinase (TIMP-1) expression in malignant non-Hodgkin's lymphomas. Blood 1999;94: 2080-9.
    • (1999) Blood , vol.94 , pp. 2080-2089
    • Kossakowska, A.E.1    Edwards, D.R.2    Prusinkiewicz, C.3    Zhang, M.C.4    Guo, D.5    Urbanski, S.J.6
  • 49
  • 50
    • 77949766590 scopus 로고    scopus 로고
    • The T-box transcription factor Tbx2: Its role in development and possible implication in cancer
    • Abrahams A, Parker MI, Prince S. The T-box transcription factor Tbx2: Its role in development and possible implication in cancer. IUBMB Life 2010;62: 92-102.
    • (2010) IUBMB Life , vol.62 , pp. 92-102
    • Abrahams, A.1    Parker, M.I.2    Prince, S.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.