Structural analysis of the Streptomyces avermitilis CYP107W1-oligomycin a complex and role of the tryptophan 178 residue

Molecules and Cells

Volumn 39, Issue 3, 2016, Pages 211-216

  Han, Songhee ^a   Pham, Tan Viet ^a   Kim, Joo Hwan ^a   Lim, Young Ran ^a   Park, Hyoung Goo ^a   Cha, Gun Su ^b   Yun, Chul Ho ^b   Chun, Young Jin ^c   Kang, Lin Woo ^a   Kim, Donghak ^a  

^a Konkuk University   (South Korea)

^b Chonnam National University   (South Korea)

^c Chung Ang University   (South Korea)

Author keywords

CYP; CYP107W1; Oligomycin; P450; Streptomyces avermitilis; X ray crystal structure

Indexed keywords

CYTOCHROME P107W1; CYTOCHROME P450; GLYCINE; OLIGOMYCIN; TRYPTOPHAN; UNCLASSIFIED DRUG; BACTERIAL PROTEIN; PROTEIN BINDING;

ARTICLE; CRYSTAL STRUCTURE; DRUG HYDROXYLATION; DRUG PROTEIN BINDING; ENZYME ACTIVE SITE; ENZYME ANALYSIS; ENZYME SUBSTRATE; HYDROPHOBICITY; MUTATION; NONHUMAN; STREPTOMYCES AVERMITILIS; STRUCTURE ANALYSIS; TITRIMETRY; TURNOVER NUMBER; BINDING SITE; CHEMISTRY; GENETICS; METABOLISM; MOLECULAR MODEL; PROTEIN SECONDARY STRUCTURE; STREPTOMYCES; X RAY CRYSTALLOGRAPHY;

BACTERIAL PROTEINS; BINDING SITES; CATALYTIC DOMAIN; CRYSTALLOGRAPHY, X-RAY; CYTOCHROME P-450 ENZYME SYSTEM; MODELS, MOLECULAR; MUTATION; OLIGOMYCINS; PROTEIN BINDING; PROTEIN STRUCTURE, SECONDARY; STREPTOMYCES; TRYPTOPHAN;

EID: 85015843548     PISSN: 10168478     EISSN: 02191032     Source Type: Journal    
DOI: 10.14348/molcells.2016.2226     Document Type: Article

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