Ochratoxin A induces ER stress and apoptosis in mesangial cells via a NADPH oxidase-derived reactive oxygen species-mediated calpain activation pathway

Oncotarget

Volumn 8, Issue 12, 2017, Pages 19376-19388

  Sheu, Meei Ling ^a,b   Shen, Chin Chang ^c   Chen, Yuan Siao ^d   Chiang, Chih Kang ^d,e  

^a TAICHUNG VETERANS GENERAL HOSPITAL   (Taiwan)

^b NATIONAL CHUNG HSING UNIVERSITY   (Taiwan)

^c INSTITUTE OF NUCLEAR ENERGY RESEARCH   (Taiwan)

^d NATIONAL TAIWAN UNIVERSITY   (Taiwan)

^e NATIONAL TAIWAN UNIVERSITY HOSPITAL   (Taiwan)

Author keywords

Apoptosis; ER stress; Mesangial cells; NADPH oxidase; Ochratoxin A

Indexed keywords

APOCYNIN; CALPAIN; CASPASE 12; CASPASE 7; GLUCOSE REGULATED PROTEIN 78; GLUCOSE REGULATED PROTEIN 94; GROWTH ARREST AND DNA DAMAGE INDUCIBLE PROTEIN 153; INITIATION FACTOR 2ALPHA; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE; OCHRATOXIN; PHOSPHOTRANSFERASE; PROTEIN PERK; REACTIVE OXYGEN METABOLITE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE; SMALL INTERFERING RNA; UNCLASSIFIED DRUG; CALCIUM CHANNEL BLOCKING AGENT; HSPA5 PROTEIN, MOUSE;

ANIMAL CELL; APOPTOSIS; ARTICLE; CONTROLLED STUDY; CYTOTOXICITY; ENDOPLASMIC RETICULUM STRESS; ENZYME ACTIVITY; GLOMERULOPATHY; MALE; MESANGIUM CELL; MOUSE; NEPHROTOXICITY; NONHUMAN; OXIDATIVE STRESS; PROTEIN CLEAVAGE; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; RAT; SIGNAL TRANSDUCTION; ANIMAL; CELL CULTURE; CELL PROLIFERATION; DRUG EFFECT; METABOLISM; OXIDATION REDUCTION REACTION; PATHOLOGY;

ANIMALS; APOPTOSIS; CALCIUM CHANNEL BLOCKERS; CALPAIN; CELL PROLIFERATION; CELLS, CULTURED; ENDOPLASMIC RETICULUM CHAPERONE BIP; ENDOPLASMIC RETICULUM STRESS; MESANGIAL CELLS; MICE; NADPH OXIDASES; OCHRATOXINS; OXIDATION-REDUCTION; OXIDATIVE STRESS; RATS; REACTIVE OXYGEN SPECIES; SIGNAL TRANSDUCTION;

EID: 85015799765     PISSN: None     EISSN: 19492553     Source Type: Journal    
DOI: 10.18632/oncotarget.14270     Document Type: Article

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