Calpain-induced endoplasmic reticulum stress and cell death following cytotoxic damage to renal cells

Toxicological Sciences

Volumn 94, Issue 1, 2006, Pages 118-128

  Muruganandan, Shanmugam ^a   Cribb, Alastair E ^a,b  

^a UNIVERSITY OF PRINCE EDWARD ISLAND   (Canada)

^b UNIVERSITY OF CALGARY   (Canada)

Author keywords

Caspase 12; ER stress; M calpain; Nephrotoxicity; Reactive chemical toxicants; Thapsigargin; Tunicamycin

Indexed keywords

CALPAIN; CASPASE 12; CYSTEINE PROTEINASE INHIBITOR; GLUCOSE REGULATED PROTEIN 78; GLUCOSE REGULATED PROTEIN 94; IODOACETAMIDE; MENADIONE; TERT BUTYL HYDROPEROXIDE; THAPSIGARGIN; TUNICAMYCIN;

ANIMAL CELL; ARTICLE; CELL DAMAGE; CELL DEATH; CONCENTRATION RESPONSE; CONTROLLED STUDY; CYTOTOXICITY; ENDOPLASMIC RETICULUM; IMMUNOBLOTTING; KIDNEY CELL; MOLECULAR DYNAMICS; NEPHROTOXICITY; NONHUMAN; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION; STATISTICAL SIGNIFICANCE;

ACRYLATES; ANIMALS; CALPAIN; CELL DEATH; CELL NUCLEUS; CELL SHAPE; CELL SURVIVAL; CHROMATIN; CYSTEINE PROTEINASE INHIBITORS; ENDOPLASMIC RETICULUM; GLYCOPROTEINS; HEAT-SHOCK PROTEINS; IMMUNOBLOTTING; IODOACETAMIDE; L-LACTATE DEHYDROGENASE; LLC-PK1 CELLS; MEMBRANE PROTEINS; OLIGOPEPTIDES; SWINE; TERT-BUTYLHYDROPEROXIDE; THAPSIGARGIN; TIME FACTORS; TUNICAMYCIN; VITAMIN K 3;

EID: 33749608803     PISSN: 10966080     EISSN: 10960929     Source Type: Journal    
DOI: 10.1093/toxsci/kfl084     Document Type: Article

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