Fluorescent Branched RNAs for High-Throughput Analysis of Dbr1 Enzyme Kinetics and Inhibition

ACS Chemical Biology

Volumn 12, Issue 3, 2017, Pages 622-627

  Katolik, Adam ^a   Clark, Nathaniel E ^b   Tago, Nobuhiro ^a   Montemayor, Eric J ^c   Hart, P John ^b,d   Damha, Masad J ^a  

^a MCGILL UNIVERSITY   (Canada)

^b UNIVERSITY OF TEXAS HEALTH SCIENCE CENTER AT SAN ANTONIO   (United States)

^c UNIVERSITY OF WISCONSIN SCHOOL OF MEDICINE AND PUBLIC HEALTH   (United States)

^d SOUTH TEXAS VETERANS HEALTH CARE SYSTEM   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

2',5' BRANCHED RNA; DEBRANCHING ENZYME; ENZYME; FLUORESCEIN DERIVATIVE; MESSENGER RNA; PHOSPHOROTHIOIC ACID; RNA; UNCLASSIFIED DRUG; FLUORESCENT DYE; RNA POLYMERASE;

ARTICLE; ENZYME INHIBITION; ENZYME KINETICS; ENZYME STRUCTURE; HIGH THROUGHPUT SCREENING; IC50; INTRON; KINETIC PARAMETERS; LINKAGE ANALYSIS; PRIORITY JOURNAL; PROTEIN HYDROLYSIS; RNA ANALYSIS; ANTAGONISTS AND INHIBITORS; CHEMISTRY; KINETICS; METABOLISM;

FLUORESCENT DYES; HIGH-THROUGHPUT SCREENING ASSAYS; KINETICS; RNA; RNA NUCLEOTIDYLTRANSFERASES;

EID: 85015765964     PISSN: 15548929     EISSN: 15548937     Source Type: Journal    
DOI: 10.1021/acschembio.6b00971     Document Type: Article

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