Salt Sensitivity of Angiogenesis Inhibition-Induced Blood Pressure Rise: Role of Interstitial Sodium Accumulation?

Hypertension

Volumn 69, Issue 5, 2017, Pages 919-926

  Lankhorst, Stephanie ^a   Severs, David ^b   Markó, Lajos ^c   Rakova, Natalia ^c,f   Titze, Jens ^d   Müller, Dominik N ^c,e   Danser, A H Jan ^a   Van Den Meiracker, Anton H ^a  

^a Division of Pharmacology and Vascular Medicine   (Netherlands)

^b ERASMUS MEDICAL CENTER   (Netherlands)

^c CHARITÉ UNIVERSITÄTSMEDIZIN BERLIN   (Germany)

^d VANDERBILT UNIVERSITY SCHOOL OF MEDICINE   (United States)

^e MAX DELBRÜCK CENTER FOR MOLECULAR MEDICINE   (Germany)

^f UNIVERSITY OF ERLANGEN NUREMBERG   (Germany)

Author keywords

angiogenesis inhibition; hypertension; lymphangiogenesis; Na+ storage; salt sensitivity; sunitinib; vascular endothelial growth factor

Indexed keywords

CHLORIDE ION; SODIUM CHLORIDE; SODIUM ION; SUNITINIB; WATER; INDOLE DERIVATIVE; PYRROLE DERIVATIVE; SODIUM INTAKE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIANGIOGENIC ACTIVITY; ARTICLE; BLOOD PRESSURE MEASUREMENT; BODY WEIGHT; CELL DENSITY; CONTROLLED STUDY; ELEVATED BLOOD PRESSURE; HYPERTENSION; KIDNEY FUNCTION; LYMPHANGIOGENESIS; MEAN ARTERIAL PRESSURE; MONONUCLEAR PHAGOCYTE; NATRIURESIS; NONHUMAN; PRIORITY JOURNAL; RAT; SALT INTAKE; TELEMETRY; WISTAR KYOTO RAT; ADMINISTRATION AND DOSAGE; ANIMAL; BLOOD PRESSURE; CHEMICALLY INDUCED; DRUG EFFECTS; MALE; PATHOPHYSIOLOGY; SKIN; SODIUM INTAKE;

ANIMALS; BLOOD PRESSURE; HYPERTENSION; INDOLES; LYMPHANGIOGENESIS; MALE; PYRROLES; RATS; RATS, INBRED WKY; SKIN; SODIUM, DIETARY;

EID: 85015752771     PISSN: 0194911X     EISSN: 15244563     Source Type: Journal    
DOI: 10.1161/HYPERTENSIONAHA.116.08565     Document Type: Article

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