Endothelin-1 as a master regulator of whole-body Na+ homeostasis

FASEB Journal

Volumn 29, Issue 12, 2015, Pages 4937-4944

  Speed, Joshua S ^a   Heimlich, J Brett ^b   Hyndman, Kelly A ^a   Fox, Brandon M ^a   Patel, Vivek ^a   Yanagisawa, Masashi ^c   Pollock, Jennifer S ^a   Titze, Jens M ^d   Pollock, David M ^a  

^a University of Alabama at Birmingham   (United States)

^b MEDICAL COLLEGE OF GEORGIA   (United States)

^c UNIVERSITY OF TSUKUBA   (Japan)

^d VANDERBILT UNIVERSITY   (United States)

Author keywords

Endothelium; Inflammation; Skin; Vascular

Indexed keywords

ATRASENTAN; ENDOTHELIN 1; MESSENGER RNA; SODIUM; SODIUM INTAKE;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; ENDOTHELIUM CELL; EXTRACELLULAR SPACE; HIGH SODIUM INTAKE; HOMEOSTASIS; HUMAN; HUMAN CELL; IC50; IN VITRO STUDY; IN VIVO STUDY; MALE; MOUSE; NONHUMAN; PLASMA OSMOLARITY; PRIORITY JOURNAL; SODIUM BLOOD LEVEL; SODIUM RESTRICTION; TISSUES; VASCULAR TISSUE; ADMINISTRATION AND DOSAGE; ANIMAL; C57BL MOUSE; KNOCKOUT MOUSE; OSMOLARITY; PHYSIOLOGY; SODIUM INTAKE;

ANIMALS; ENDOTHELIN-1; HOMEOSTASIS; MALE; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; OSMOLAR CONCENTRATION; SODIUM; SODIUM, DIETARY;

EID: 84959507656     PISSN: 08926638     EISSN: 15306860     Source Type: Journal    
DOI: 10.1096/fj.15-276584     Document Type: Article

References (26)

1. Hall, J. E., Granger, J. P., do Carmo, J. M., da Silva, A. A., Dubinion, J., George, E., Hamza, S., Speed, J., and Hall, M. E. (2012) Hypertension: physiology and pathophysiology. Compr. Physiol. 2, 2393-2442
2. Calhoun, D. A., Jones, D., Textor, S., Goff, D. C., Murphy, T. P., Toto, R. D., White, A., Cushman, W. C., White, W., Sica, D., Ferdinand, K., Giles, T. D., Falkner, B., and Carey, R. M. (2008) Resistant hypertension: diagnosis, evaluation, and treatment. A scientific statement from the American Heart Association Professional Education Committee of the Council for High Blood Pressure Research. Hypertension 51, 1403-1419
3. Titze, J., Lang, R., Ilies, C., Schwind, K. H., Kirsch, K. A., Dietsch, P., Luft, F. C., and Hilgers, K. F. (2003) Osmotically inactive skin Na+ storage in rats. Am. J. Physiol. Renal Physiol. 285, F1108-F1117
4. Cannon, W. (1929) Organization for physiological homeostasis. Physiol. Rev. 9, 399-431
5. Machnik, A., Dahlmann, A., Kopp, C., Goss, J., Wagner, H., van Rooijen, N., Eckardt, K. U., Müller, D. N., Park, J. K., Luft, F. C., Kerjaschki, D., and Titze, J. (2010) Mononuclear phagocyte system depletion blocks interstitial tonicity-responsive enhancer binding protein/vascular endothelial growth factor C expression and induces salt-sensitive hypertension in rats. Hypertension 55, 755-761
6. Machnik, A., Neuhofer, W., Jantsch, J., Dahlmann, A., Tammela, T., Machura, K., Park, J. K., Beck, F. X., Müller, D. N., Derer, W., Goss, J., Ziomber, A., Dietsch, P., Wagner, H., van Rooijen, N., Kurtz, A., Hilgers, K. F., Alitalo, K., Eckardt, K. U., Luft, F. C., Kerjaschki, D., and Titze, J. (2009) Macrophages regulate salt-dependent volume and blood pressure by a vascular endothelial growth factor-C-dependent buffering mechanism. Nat. Med. 15, 545-552
7. Wiig, H., Schröder, A., Neuhofer, W., Jantsch, J., Kopp, C., Karlsen, T. V., Boschmann, M., Goss, J., Bry, M., Rakova, N., Dahlmann, A., Brenner, S., Tenstad, O., Nurmi, H., Mervaala, E., Wagner, H., Beck, F. X., Müller, D. N., Kerjaschki, D., Luft, F. C., Harrison, D. G., Alitalo, K., and Titze, J. (2013) Immune cells control skinlymphatic electrolyte homeostasis and blood pressure. J. Clin. Invest. 123, 2803-2815
8. Pollock, D. M., and Pollock, J. S. (2001) Evidence for endothelin involvement in the response to high salt. Am. J. Physiol. Renal Physiol. 281, F144-F150
9. Kohan, D. E., Rossi, N. F., Inscho, E. W., and Pollock, D. M. (2011) Regulation of blood pressure and salt homeostasis by endothelin. Physiol. Rev. 91, 1-77
10. Kohan, D. E., Inscho, E. W., Wesson, D., and Pollock, D. M. (2011) Physiology of endothelin and the kidney. Compr. Physiol. 1, 883-919
11. Kohan, D. E., and Padilla, E. (1993) Osmolar regulation of endothelin-1 production by rat inner medullary collecting duct. J. Clin. Invest. 91, 1235-1240
12. Herrera, M., and Garvin, J. L. (2005) A high-salt diet stimulates thick ascending limb eNOS expression by raising medullary osmolality and increasing release of endothelin-1. Am. J. Physiol. Renal Physiol. 288, F58-F64
13. Tsai, Y. H., Ohkita, M., and Gariepy, C. E. (2006) Chronic high-sodium diet increases aortic wall endothelin-1 expression in a blood pressure-independent fashion in rats. Exp. Biol. Med. (Maywood) 231, 813-817
14. Kisanuki, Y. Y., Emoto, N., Ohuchi, T., Widyantoro, B., Yagi, K., Nakayama, K., Kedzierski, R. M., Hammer, R. E., Yanagisawa, H., Williams, S. C., Richardson, J. A., Suzuki, T., and Yanagisawa, M. (2010) Low blood pressure in endothelial cell-specific endothelin 1 knockout mice. Hypertension 56, 121-128
15. Winn, M., von Geldern, T. W., Opgenorth, T. J., Jae, H. S., Tasker, A. S., Boyd, S. A., Kester, J. A., Mantei, R. A., Bal, R., Sorensen, B. K., Wu-Wong, J. R., Chiou, W. J., Dixon, D. B., Novosad, E. I., Hernandez, L., and Marsh, K. C. (1996) 2,4-Diarylpyrrolidine-3-carboxylic acids - potent ETA selective endothelin receptor antagonists. 1. Discovery of A-127722. J. Med. Chem. 39, 1039-1048
16. Titze, J., Krause, H., Hecht, H., Dietsch, P., Rittweger, J., Lang, R., Kirsch, K. A., and Hilgers, K. F. (2002) Reduced osmotically inactive Na storage capacity and hypertension in the Dahl model. Am. J. Physiol. Renal Physiol. 283, F134-F141
17. Sasser, J. M., Pollock, J. S., and Pollock, D. M. (2002) Renal endothelin in chronic angiotensin II hypertension. Am. J. Physiol. Regul. Integr. Comp. Physiol. 283, R243-R248
18. Pfaffl, M. W. (2001) A new mathematical model for relative quantification in real-time RT-PCR. Nucleic Acids Res. 29, e45
19. Kopp, C., Linz, P., Dahlmann, A., Hammon, M., Jantsch, J., Müller, D. N., Schmieder, R. E., Cavallaro, A., Eckardt, K. U., Uder, M., Luft, F. C., and Titze, J. (2013) 23Na magnetic resonance imaging-determined tissue sodium in healthy subjects and hypertensive patients. Hypertension 61, 635-640
20. Suckling, R. J., He, F. J., Markandu, N. D., and MacGregor, G. A. (2012) Dietary salt influences postprandial plasma sodium concentration and systolic blood pressure. Kidney Int. 81, 407-411
21. Boesen, E. I., and Pollock, D. M. (2007) Acute increases of renal medullary osmolality stimulate endothelin release from the kidney. Am. J. Physiol. Renal Physiol. 292, F185-F191
22. Stuart, D., Rees, S., Woodward, S. K., Koesters, R., Strait, K. A., and Kohan, D. E. (2012) Disruption of the endothelin A receptor in the nephron causes mild fluid volume expansion. BMC Nephrol. 13, 166
23. Titze, J. (2009) Water-free sodium accumulation. Semin. Dial. 22, 253-255
24. Saleh, M. A., Boesen, E. I., Pollock, J. S., Savin, V. J., and Pollock, D. M. (2010) Endothelin-1 increases glomerular permeability and inflammation independent of blood pressure in the rat. Hypertension 56, 942-949
25. Titze, J., and Machnik, A. (2010) Sodium sensing in the interstitium and relationship to hypertension. Curr. Opin. Nephrol. Hypertens. 19, 385-392
26. Dahlmann, A., Dörfelt, K., Eicher, F., Linz, P., Kopp, C., Mössinger, I., Horn, S., Büschges-Seraphin, B., Wabel, P., Hammon, M., Cavallaro, A., Eckardt, K. U., Kotanko, P., Levin, N. W., Johannes, B., Uder, M., Luft, F. C., Müller, D. N., and Titze, J. M. (2015) Magnetic resonance-determined sodium removal from tissue stores in hemodialysis patients. Kidney Int. 87, 434-441