The IFN-λ-IFN-λR1-IL-10Rβ Complex Reveals Structural Features Underlying Type III IFN Functional Plasticity

Immunity

Volumn 46, Issue 3, 2017, Pages 379-392

  Mendoza, Juan L ^a   Schneider, William M ^b   Hoffmann, Hans Heinrich ^b   Vercauteren, Koen ^b   Jude, Kevin M ^a   Xiong, Anming ^a   Moraga, Ignacio ^a   Horton, Tim M ^a   Glenn, Jeffrey S ^a   de Jong, Ype P ^b,c   Rice, Charles M ^b   Garcia, K Christopher ^a  

^a STANFORD UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b ROCKEFELLER UNIVERSITY   (United States)

^c WEILL CORNELL MEDICAL COLLEGE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIVIRUS AGENT; CYTOKINE; INTERFERON; INTERFERON LAMBDA; INTERFERON LAMBDA RECEPTOR 1; INTERFERON RECEPTOR; INTERFERON TYPE III; INTERLEUKIN 10; INTERLEUKIN 10 RECEPTOR BETA; TYROSINE; UNCLASSIFIED DRUG; INTERLEUKIN 10 RECEPTOR;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIPROLIFERATIVE ACTIVITY; ANTIVIRAL ACTIVITY; ARTICLE; BINDING AFFINITY; COMPLEX FORMATION; CONFORMATIONAL TRANSITION; CONTROLLED STUDY; CRYSTALLIZATION; DRUG POTENCY; EC50; HEPATITIS B; HUMAN; HUMAN CELL; HYDROPHOBICITY; IN VITRO STUDY; IN VIVO STUDY; MOLECULAR RECOGNITION; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN ENGINEERING; PROTEIN EXPRESSION; PROTEIN FAMILY; PROTEIN FUNCTION; SIGNAL TRANSDUCTION; STRUCTURE ACTIVITY RELATION; STRUCTURE ANALYSIS; YEAST; ANIMAL; CELL LINE; FLOW CYTOMETRY; IMMUNOLOGY; POLYMERASE CHAIN REACTION; SURFACE PLASMON RESONANCE; X RAY CRYSTALLOGRAPHY;

ANIMALS; CELL LINE; CRYSTALLOGRAPHY, X-RAY; FLOW CYTOMETRY; HUMANS; INTERFERONS; MICE; POLYMERASE CHAIN REACTION; RECEPTORS, INTERFERON; RECEPTORS, INTERLEUKIN-10; SURFACE PLASMON RESONANCE;

EID: 85015736550     PISSN: 10747613     EISSN: 10974180     Source Type: Journal    
DOI: 10.1016/j.immuni.2017.02.017     Document Type: Article

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