Rapid profiling and pharmacokinetic studies of major compounds in crude extract from Polygonum multiflorum by UHPLC-Q-TOF-MS and UPLC–MS/MS

Journal of Pharmaceutical and Biomedical Analysis

Volumn 140, Issue , 2017, Pages 45-61

  Wang, Linlin ^a   Sang, Mangmang ^a   Liu, Erwei ^a   Banahene, Prince Osei ^a   Zhang, Yi ^a   Wang, Tao ^a   Han, Lifeng ^a   Gao, Xiumei ^a  

^a TIANJIN UNIVERSITY OF TRADITIONAL CHINESE MEDICINE   (China)

Author keywords

Pharmacokinetics; Polygonum multiflorum; UHPLC Q TOF MS; UPLC MS MS

Indexed keywords

ALOE EMODIN; ANTHRAQUINONE DERIVATIVE; CAFFEIC ACID; CHLOROGENIC ACID; EMODIN; FLAVONE DERIVATIVE; GALLIC ACID; KAEMPFEROL; NAPHTHALENE DERIVATIVE; PHYSCION; PICEID; PLANT EXTRACT; POLYGONUM MULTIFLORUM EXTRACT; PROTOCATECHUIC ACID; PSORALEN; QUERCETIN; RESVERATROL; RHEIN; STILBENE DERIVATIVE; UNCLASSIFIED DRUG; HERBACEOUS AGENT;

ANIMAL EXPERIMENT; ARTICLE; BLOOD ANALYSIS; BLOOD SAMPLING; CONTROLLED STUDY; DRUG BLOOD LEVEL; DRUG DOSE COMPARISON; DRUG MEGADOSE; DRUG SELECTIVITY; DRUG SPECIFICITY; FALLOPIA MULTIFLORA; LOW DRUG DOSE; MALE; MAXIMUM PLASMA CONCENTRATION; NONHUMAN; PLASMA CONCENTRATION-TIME CURVE; PRIORITY JOURNAL; QUADRUPOLE MASS SPECTROMETRY; QUANTITATIVE ANALYSIS; RAT; RETENTION TIME; TANDEM MASS SPECTROMETRY; TIME OF FLIGHT MASS SPECTROMETRY; ULTRA PERFORMANCE LIQUID CHROMATOGRAPHY; ANIMAL; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY;

ANIMALS; ANTHRAQUINONES; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; DRUGS, CHINESE HERBAL; FALLOPIA MULTIFLORA; RATS; TANDEM MASS SPECTROMETRY;

EID: 85015725330     PISSN: 07317085     EISSN: 1873264X     Source Type: Journal    
DOI: 10.1016/j.jpba.2017.03.016     Document Type: Article

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