Eighteen cases of liver injury following ingestion of polygonum multiflorum

Complementary Therapies in Medicine

Volumn 22, Issue 1, 2014, Pages 70-74

  Dong, Huihui ^a,b   Slain, Douglas ^c   Cheng, Junchi ^a,b   Ma, Weihang ^a,b,d   Liang, Weifeng ^a,b  

^a ZHEJIANG UNIVERSITY   (China)

^b ZHEJIANG UNIVERSITY   (China)

^c WEST VIRGINIA UNIVERSITY   (United States)

^d Zhejiang Province Health Bureau Center of Information   (China)

Author keywords

Fo ti; Hepatotoxicity; Polygonum multiflorum

Indexed keywords

FO-TI; HEPATOTOXICITY; POLYGONUM MULTIFLORUM;

ADOLESCENT; ADULT; BILIRUBIN; DRUG-INDUCED LIVER INJURY; DRUGS, CHINESE HERBAL; ENZYMES; FEMALE; HUMANS; MALE; MIDDLE AGED; POLYGONUM; YOUNG ADULT;

EID: 84894247676     PISSN: 09652299     EISSN: 18736963     Source Type: Journal    
DOI: 10.1016/j.ctim.2013.12.008     Document Type: Article

References (22)

1. Anon. Fo-ti (Polygonum multiflorum). 2012 natural standard monograph 2012, Natural Standard, Inc., Somerville Council for International Organizations of Medical Sciences, MA, USA.
2. Lv G., Gu H., Chen S., Lou Z., Shan L. Pharmacokinetic profile of 2,3,5,4'-tetrahydroxystilbene-2-O-beta-d-glucoside in mice after oral administration of Polygonum multiflorum extract. Drug Dev Ind Pharm 2012, 38:248-255.
3. Chan Y.C., Wang M.F., Chen Y.C., Yang D.Y., Lee M.S., Cheng F.C. Long-term administration of Polygonum multiflorum Thnb reduces cerebral ischemia-induced infarct volume in gerbils. Am J Chin Med 2003, 31:71-77.
4. Ryu G., Ju J.H., Park Y.J., Ryu S.Y., Choi B.W., Lee B.H. The radical scavenging effects of stilbene glucosides from Polygonum multiflorum. Arch Pharm Res 2002, 25:636-639.
5. Park H.J., Zhang N., Park D.K. Topical application of Polygonum multiflorum extract induces hair growth of resting hair follicles through upregulating Shh and beta-catenin expression in C57BL/6 mice. J Ethnopharmacol 2011, 135:369-375.
6. Chen H.S., Liu Y., Lin L.Q., Zhao J.L., Zhang C.P., Jin J.C., et al. Anti-proliferative effect of an extract of the root of Polygonum multiflorum Thunb. on MCF-7 human breast cancer cells and the possible mechanisms. Mol Med Rep 2011, 4:1313-1319.
7. Li X., Matsumoto K., Murakami Y., Tezuka Y., Wu Y., Kadota S. Neuroprotective effects of Polygonum multiflorum on nigrostriatal dopaminergic degeneration induced by paraquat and maneb in mice. Pharmacol Biochem Behav 2005, 82:345-352.
8. Shou-Wu-Pian [package insert] 2010, Chen Ji Pharmaceutical Co., Ltd., Shaanxi Province.
9. Jung K.A., Min H.J., Yoo S.S., et al. Drug-induced liver injury: twenty five cases of acute hepatitis following ingestion of Polygonum multiflorum Thunb. Gut Liver 2011, 5:493-499.
10. Mazzanti G., Battinelli L., Danile C., et al. New case of acute hepatitis following the consumption of Shou Wu Pian, a Chinese herbal product derived from Polygonum multiflorum. Ann Intern Med 2004, 140:W30.
11. Panis B., Wong D.R., Hooymans P.M., DeSmet P.A., Rosias P.P. Recurrent toxic hepatitis in a Caucasian girl related to the use of Shou-Wu-Pian, a Chinese herbal preparation. J Pediatr Gastroenterol Nutr 2005, 41:256-258.
12. Wu X., Chen X., Huang Q., Fang D. Toxicity of raw and processed roots of Polygonum multiflorum. Fitoterapia 2012, 83:469-475.
13. Grundy S.M., Cleeman J.I., Daniels S.R., et al. Diagnosis and management of the metabolic syndrome. An American Heart Association/National Heart, Lung, and Blood Institute Scientific Statement. Executive summary. Cardiol Rev 2005, 13:322-327.
14. Benichou C. Criteria of drug-induced liver disorders. Report of an international consensus meeting. J Hepatol 1990, 11:272-276.
15. Chinese Pharmacopoeia Commission The Chinese Pharmacopoeia 2010, 165. Chinese Medical Technology Press, Beijing. 1st ed.
16. Kaplowitz N. Idiosyncratic drug hepatotoxicity. Nat Rev Drug Discov 2005, 4:489-499.
17. Hennes E.M., Zeniya M., Czaja A.J., et al. Simplified criteria for the diagnosis of autoimmune hepatitis. Hepatology 2008, 48:169-176.
18. Verma S., Kaplowitz N. Diagnosis, management and prevention of drug-induced liver injury. Gut 2009, 58:1555-1564.
19. Hunter J., Maxwell J.D., Stewart J.D., Stewart D.A., Williams R. Urinary d-glucaric acid excretion and total liver ontent of cytochrome P-450 in guinea-pigs: relationship during enzyme induction and following inhibition of protein synthesis. Biochem Pharmacol 1973, 22:743-747.
20. Gilbert J.C., Scott A.K., Galloway D.B., Petrie J.C. Ethosuximide: liver enzyme induction and d-glucaric acid excretion. Br J Clin Pharmacol 1974, 1:249-252.
21. Huang K.C. Pharmacology of Chinese herbs 1998, 121-122. CRC Press, Boca Raton. 2nd ed.
22. MacLennan A.H., Wilson D.H., Taylor A.W. The escalating cost and prevalence of alternative medicine. Prevent Med 2002, 35:166-173.