-
1
-
-
84857236823
-
Lapatinib with trastuzumab for HER2-positive early breast cancer (NeoALTTO): A randomised, openlabel, multicentre, phase 3 trial
-
Baselga J, Bradbury I, Eidtmann H et al. Lapatinib with trastuzumab for HER2-positive early breast cancer (NeoALTTO): A randomised, openlabel, multicentre, phase 3 trial. Lancet 2012; 379: 633-640.
-
(2012)
Lancet
, vol.379
, pp. 633-640
-
-
Baselga, J.1
Bradbury, I.2
Eidtmann, H.3
-
2
-
-
84927620697
-
PIK3CA mutations are associated with decreased benefit to neoadjuvant human epidermal growth factor receptor 2-targeted therapies in breast cancer
-
Majewski IJ, Nuciforo P, Mittempergher L et al. PIK3CA mutations are associated with decreased benefit to neoadjuvant human epidermal growth factor receptor 2-targeted therapies in breast cancer. J Clin Oncol 2015; 33(12): 1334-1339.
-
(2015)
J Clin Oncol
, vol.33
, Issue.12
, pp. 1334-1339
-
-
Majewski, I.J.1
Nuciforo, P.2
Mittempergher, L.3
-
3
-
-
84982889739
-
Tumor-infiltrating lymphocytes and associations with pathological complete response and event-free survival in her2-positive early-stage breast cancer treated with lapatinib and trastuzumab A secondary analysis of the NeoALTTO Trial
-
Salgado R, Denkert C, Campbell C et al. Tumor-infiltrating lymphocytes and associations with pathological complete response and event-free survival in her2-positive early-stage breast cancer treated with lapatinib and trastuzumab A secondary analysis of the NeoALTTO Trial. JAMA Oncol 2015; 1(4): 448-455.
-
(2015)
JAMA Oncol
, vol.1
, Issue.4
, pp. 448-455
-
-
Salgado, R.1
Denkert, C.2
Campbell, C.3
-
4
-
-
84907550640
-
PIK3CA mutations are associated with lower rates of pathologic complete response to anti-human epidermal growth factor receptor 2 (HER2) therapy in primary HER2-overexpressing breast cancer
-
Loibl S, Von Minckwitz G, Schneeweiss A et al. PIK3CA mutations are associated with lower rates of pathologic complete response to anti-human epidermal growth factor receptor 2 (HER2) therapy in primary HER2-overexpressing breast cancer. J Clin Oncol 2014; 32(29): 3212-3220.
-
(2014)
J Clin Oncol
, vol.32
, Issue.29
, pp. 3212-3220
-
-
Loibl, S.1
Von Minckwitz, G.2
Schneeweiss, A.3
-
5
-
-
84925273291
-
Genomic analysis reveals that immune function genes are strongly linked to clinical outcome in the North Central Cancer Treatment Group N9831 adjuvant trastuzumab trial
-
Perez EA, Thompson EA, Ballman KV et al. Genomic analysis reveals that immune function genes are strongly linked to clinical outcome in the North Central Cancer Treatment Group N9831 adjuvant trastuzumab trial. J Clin Oncol 2015; 33: 701-708.
-
(2015)
J Clin Oncol
, vol.33
, pp. 701-708
-
-
Perez, E.A.1
Thompson, E.A.2
Ballman, K.V.3
-
6
-
-
84939456648
-
Measurement of domain-specific HER2 (ERBB2) expression may classify benefit from trastuzumab in breast cancer
-
Carvajal-Hausdorf D., Schalper K., Pusztai L et al. Measurement of domain-specific HER2 (ERBB2) expression may classify benefit from trastuzumab in breast cancer. J Natl Cancer Inst 2015; 107(8): djv136. doi: 10.1093/jnci/djv136.
-
(2015)
J Natl Cancer Inst
, vol.107
, Issue.8
-
-
Carvajal-Hausdorf, D.1
Schalper, K.2
Pusztai, L.3
-
7
-
-
84964307819
-
High HER2 expression correlates with response to the combination of lapatinib and trastuzumab
-
Scaltriti M, Nuciforo P, Bradbury I et al. High HER2 expression correlates with response to the combination of lapatinib and trastuzumab. Clin Cancer Res 2015; 21(3): 569-576.
-
(2015)
Clin Cancer Res
, vol.21
, Issue.3
, pp. 569-576
-
-
Scaltriti, M.1
Nuciforo, P.2
Bradbury, I.3
-
8
-
-
84921377658
-
Targeting HER2 for the Treatment of Breast Cancer
-
Rimawi MF, Schiff R, Osborne KC. Targeting HER2 for the Treatment of Breast Cancer. Annual Rev Med 2015; 66: 111-128.
-
(2015)
Annual Rev Med
, vol.66
, pp. 111-128
-
-
Rimawi, M.F.1
Schiff, R.2
Osborne, K.C.3
-
9
-
-
27344435774
-
Gene set enrichment analysis: a knowledge-based approach for interpreting genome-wide expression profiles
-
Subramanian A, Tamayo P, Mootha VK et al. Gene set enrichment analysis: a knowledge-based approach for interpreting genome-wide expression profiles. Proc Natl Acad Sci U S A. 2005; 102(43):15545-15550.
-
(2005)
Proc Natl Acad Sci U S A
, vol.102
, Issue.43
, pp. 15545-15550
-
-
Subramanian, A.1
Tamayo, P.2
Mootha, V.K.3
-
10
-
-
84884994218
-
"The Cancer Genome Atlas Pan-Cancer analysis project."
-
Cancer Genome Atlas Research, Network. "The Cancer Genome Atlas Pan-Cancer analysis project." Nature Genet 2013; 45(10): 1113-1120.
-
(2013)
Nature Genet
, vol.45
, Issue.10
, pp. 1113-1120
-
-
-
11
-
-
35148885729
-
A functional genetic approach identifies the PI3K pathway as a major determinant of trastuzumab resistance in breast cancer
-
Berns K, Horlings HM, Hennessy BT et al. A functional genetic approach identifies the PI3K pathway as a major determinant of trastuzumab resistance in breast cancer. Cancer Cell 2007; 12: 395-402.
-
(2007)
Cancer Cell
, vol.12
, pp. 395-402
-
-
Berns, K.1
Horlings, H.M.2
Hennessy, B.T.3
-
12
-
-
0036633164
-
Constitutive and inducible Akt activity promotes resistance to chemotherapy, trastuzumab, or tamoxifen in breast cancer cells
-
Clark AS, West K, Streicher S et al. Constitutive and inducible Akt activity promotes resistance to chemotherapy, trastuzumab, or tamoxifen in breast cancer cells. Mol Cancer Ther 2002; 1:707-717.
-
(2002)
Mol Cancer Ther
, vol.1
, pp. 707-717
-
-
Clark, A.S.1
West, K.2
Streicher, S.3
-
13
-
-
84901677114
-
Recurrent gain-of-function mutations of RHOA in diffuse-type gastric carcinoma
-
Kakiuchi M, Nishizawa T, Ueda H et al. Recurrent gain-of-function mutations of RHOA in diffuse-type gastric carcinoma. Nature Genet 2014; 46(6): 583-587.
-
(2014)
Nature Genet
, vol.46
, Issue.6
, pp. 583-587
-
-
Kakiuchi, M.1
Nishizawa, T.2
Ueda, H.3
-
14
-
-
9244237677
-
Functional analysis of the contribution of RhoA and RhoC GTPases to invasive breast carcinoma
-
Simpson KJ, Dugan AS, Mercurio AM Functional analysis of the contribution of RhoA and RhoC GTPases to invasive breast carcinoma. Cancer Res 2004; 64(23): 8694-8701.
-
(2004)
Cancer Res
, vol.64
, Issue.23
, pp. 8694-8701
-
-
Simpson, K.J.1
Dugan, A.S.2
Mercurio, A.M.3
-
15
-
-
78649863822
-
ErbB2 receptor controls microtubule capture by recruiting ACF7 to the plasma membrane of migrating cells
-
Zaoui K, Benseddik K, Daou P et al. ErbB2 receptor controls microtubule capture by recruiting ACF7 to the plasma membrane of migrating cells. Proc Natl Acad Sci USA 2010; 107(43): 18517-18522.
-
(2010)
Proc Natl Acad Sci USA
, vol.107
, Issue.43
, pp. 18517-18522
-
-
Zaoui, K.1
Benseddik, K.2
Daou, P.3
-
16
-
-
19944432271
-
Anti-RhoA and anti-RhoC siRNAs inhibit the proliferation and invasiveness of MDA-MB-231 breast cancer cells in vitro and in vivo
-
Pillé JY, Denoyelle C, Varet J et al. Anti-RhoA and anti-RhoC siRNAs inhibit the proliferation and invasiveness of MDA-MB-231 breast cancer cells in vitro and in vivo. Mol Ther 2005; 11(2): 267-274.
-
(2005)
Mol Ther
, vol.11
, Issue.2
, pp. 267-274
-
-
Pillé, J.Y.1
Denoyelle, C.2
Varet, J.3
-
17
-
-
79958706977
-
RACK1 promotes breast carcinoma migration/metastasis via activation of the RhoA/Rho kinase pathway
-
Cao XX, Xu JD, Xu JW et al. RACK1 promotes breast carcinoma migration/metastasis via activation of the RhoA/Rho kinase pathway. Breast Cancer Res Treat 2011; 126(3): 555-563.
-
(2011)
Breast Cancer Res Treat
, vol.126
, Issue.3
, pp. 555-563
-
-
Cao, X.X.1
Xu, J.D.2
Xu, J.W.3
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