메뉴 건너뛰기




Volumn 36, Issue 29, 2017, Pages 4161-4170

Compromised BRCA1-PALB2 interaction is associated with breast cancer risk

Author keywords

[No Author keywords available]

Indexed keywords

BRCA1 PROTEIN; CHECKPOINT KINASE 2; EPIDERMAL GROWTH FACTOR RECEPTOR 2; ESTROGEN RECEPTOR; LETROZOLE; MITOMYCIN; OLAPARIB; PALB2 PROTEIN; PROGESTERONE RECEPTOR; PROTEIN; PROTEIN P53; UNCLASSIFIED DRUG; BRCA1 PROTEIN, HUMAN; NUCLEAR PROTEIN; PALB2 PROTEIN, HUMAN; PROTEIN BINDING; TUMOR SUPPRESSOR PROTEIN;

EID: 85015676207     PISSN: 09509232     EISSN: 14765594     Source Type: Journal    
DOI: 10.1038/onc.2017.46     Document Type: Article
Times cited : (66)

References (55)
  • 1
    • 62549115236 scopus 로고    scopus 로고
    • PALB2 links BRCA1 and BRCA2 in the DNA-damage response
    • Zhang F, Ma J, Wu J, Ye L, Cai H, Xia B et al. PALB2 links BRCA1 and BRCA2 in the DNA-damage response. Curr Biol 2009; 19: 524-529.
    • (2009) Curr Biol , vol.19 , pp. 524-529
    • Zhang, F.1    Ma, J.2    Wu, J.3    Ye, L.4    Cai, H.5    Xia, B.6
  • 2
    • 66349096607 scopus 로고    scopus 로고
    • PALB2 is an integral component of the BRCA complex required for homologous recombination repair
    • Sy SM, Huen MS, Chen J. PALB2 is an integral component of the BRCA complex required for homologous recombination repair. Proc Natl Acad Sci USA 2009; 106: 7155-7160.
    • (2009) Proc Natl Acad Sci USA , vol.106 , pp. 7155-7160
    • Sy, S.M.1    Huen, M.S.2    Chen, J.3
  • 3
    • 67651166786 scopus 로고    scopus 로고
    • PALB2 functionally connects the breast cancer susceptibility proteins BRCA1 and BRCA2
    • Zhang F, Fan Q, Ren K, Andreassen PR. PALB2 functionally connects the breast cancer susceptibility proteins BRCA1 and BRCA2. Mol Cancer Res 2009; 7: 1110-1118.
    • (2009) Mol Cancer Res , vol.7 , pp. 1110-1118
    • Zhang, F.1    Fan, Q.2    Ren, K.3    Andreassen, P.R.4
  • 4
    • 33745200945 scopus 로고    scopus 로고
    • Control of BRCA2 cellular and clinical functions by a nuclear partner PALB2
    • Xia B, Sheng Q, Nakanishi K, Ohashi A, Wu J, Christ N et al. Control of BRCA2 cellular and clinical functions by a nuclear partner, PALB2. Mol Cell 2006; 22: 719-729.
    • (2006) Mol Cell , vol.22 , pp. 719-729
    • Xia, B.1    Sheng, Q.2    Nakanishi, K.3    Ohashi, A.4    Wu, J.5    Christ, N.6
  • 5
    • 77957329128 scopus 로고    scopus 로고
    • PALB2/FANCN: Recombining cancer and Fanconi anemia
    • Tischkowitz M, Xia B. PALB2/FANCN: Recombining cancer and Fanconi anemia. Cancer Res 2010; 70: 7353-7359.
    • (2010) Cancer Res , vol.70 , pp. 7353-7359
    • Tischkowitz, M.1    Xia, B.2
  • 6
    • 81055126264 scopus 로고    scopus 로고
    • Mutations in 12 genes for inherited ovarian, fallopian tube, and peritoneal carcinoma identified by massively parallel sequencing
    • Walsh T, Casadei S, Lee MK, Pennil CC, Nord AS, Thornton AM et al. Mutations in 12 genes for inherited ovarian, fallopian tube, and peritoneal carcinoma identified by massively parallel sequencing. Proc Natl Acad Sci USA 2011; 108: 18032-18037.
    • (2011) Proc Natl Acad Sci USA , vol.108 , pp. 18032-18037
    • Walsh, T.1    Casadei, S.2    Lee, M.K.3    Pennil, C.C.4    Nord, A.S.5    Thornton, A.M.6
  • 9
    • 84869034368 scopus 로고    scopus 로고
    • PALB2 self-interaction controls homologous recombination
    • Buisson R, Masson JY. PALB2 self-interaction controls homologous recombination. Nucleic Acids Res 2012; 40: 10312-10323.
    • (2012) Nucleic Acids Res , vol.40 , pp. 10312-10323
    • Buisson, R.1    Masson, J.Y.2
  • 10
    • 67650566367 scopus 로고    scopus 로고
    • PALB2 regulates recombinational repair through chromatin association and oligomerization
    • Sy SM, Huen MS, Zhu Y, Chen J. PALB2 regulates recombinational repair through chromatin association and oligomerization. J Biol Chem 2009; 284: 18302-18310.
    • (2009) J Biol Chem , vol.284 , pp. 18302-18310
    • Sy, S.M.1    Huen, M.S.2    Zhu, Y.3    Chen, J.4
  • 11
    • 79952741549 scopus 로고    scopus 로고
    • Contribution of inherited mutations in the BRCA2-interacting protein PALB2 to familial breast cancer
    • Casadei S, Norquist BM, Walsh T, Stray S, Mandell JB, Lee MK et al. Contribution of inherited mutations in the BRCA2-interacting protein PALB2 to familial breast cancer. Cancer Res 2011; 71: 2222-2229.
    • (2011) Cancer Res , vol.71 , pp. 2222-2229
    • Casadei, S.1    Norquist, B.M.2    Walsh, T.3    Stray, S.4    Mandell, J.B.5    Lee, M.K.6
  • 12
    • 33846569450 scopus 로고    scopus 로고
    • Biallelic mutations in PALB2 cause Fanconi anemia subtype FA-N and predispose to childhood cancer
    • Reid S, Schindler D, Hanenberg H, Barker K, Hanks S, Kalb R et al. Biallelic mutations in PALB2 cause Fanconi anemia subtype FA-N and predispose to childhood cancer. Nat Genet 2007; 39: 162-164.
    • (2007) Nat Genet , vol.39 , pp. 162-164
    • Reid, S.1    Schindler, D.2    Hanenberg, H.3    Barker, K.4    Hanks, S.5    Kalb, R.6
  • 13
    • 84868240146 scopus 로고    scopus 로고
    • Ploidy and large-scale genomic instability consistently identify basal-like breast carcinomas with BRCA1/2 inactivation
    • Popova T, Manie E, Rieunier G, Caux-Moncoutier V, Tirapo C, Dubois T et al. Ploidy and large-scale genomic instability consistently identify basal-like breast carcinomas with BRCA1/2 inactivation. Cancer Res 2012; 72: 5454-5462.
    • (2012) Cancer Res , vol.72 , pp. 5454-5462
    • Popova, T.1    Manie, E.2    Rieunier, G.3    Caux-Moncoutier, V.4    Tirapo, C.5    Dubois, T.6
  • 14
    • 84973594792 scopus 로고    scopus 로고
    • Landscape of somatic mutations in 560 breast cancer whole-genome sequences
    • Nik-Zainal S, Davies H, Staaf J, Ramakrishna M, Glodzik D, Zou X et al. Landscape of somatic mutations in 560 breast cancer whole-genome sequences. Nature 2016; 534: 47-54.
    • (2016) Nature , vol.534 , pp. 47-54
    • Nik-Zainal, S.1    Davies, H.2    Staaf, J.3    Ramakrishna, M.4    Glodzik, D.5    Zou, X.6
  • 16
    • 33846601829 scopus 로고    scopus 로고
    • Fanconi anemia is associated with a defect in the BRCA2 partner PALB2
    • Xia B, Dorsman JC, Ameziane N, de Vries Y, Rooimans MA, Sheng Q et al. Fanconi anemia is associated with a defect in the BRCA2 partner PALB2. Nat Genet 2007; 39: 159-161.
    • (2007) Nat Genet , vol.39 , pp. 159-161
    • Xia, B.1    Dorsman, J.C.2    Ameziane, N.3    De Vries, Y.4    Ma, R.5    Sheng, Q.6
  • 17
    • 84980347772 scopus 로고    scopus 로고
    • Homologous recombination deficiency (HRD) score predicts response to platinum-containing neoadjuvant chemotherapy in patients with triple negative breast cancer
    • Telli ML, Timms KM, Reid JE, Hennessy B, Mills GB, Jensen KC et al. Homologous recombination deficiency (HRD) score predicts response to platinum-containing neoadjuvant chemotherapy in patients with triple negative breast cancer. Clin Cancer Res 2016; 22: 3764-3773.
    • (2016) Clin Cancer Res , vol.22 , pp. 3764-3773
    • Telli, M.L.1    Timms, K.M.2    Reid, J.E.3    Hennessy, B.4    Mills, G.B.5    Jensen, K.C.6
  • 18
    • 84893470371 scopus 로고    scopus 로고
    • Germline and somatic mutations in homologous recombination genes predict platinum response and survival in ovarian, fallopian tube, and peritoneal carcinomas
    • Pennington KP, Walsh T, Harrell MI, Lee MK, Pennil CC, Rendi MH et al. Germline and somatic mutations in homologous recombination genes predict platinum response and survival in ovarian, fallopian tube, and peritoneal carcinomas. Clin Cancer Res 2014; 20: 764-775.
    • (2014) Clin Cancer Res , vol.20 , pp. 764-775
    • Kp, P.1    Walsh, T.2    Harrell, M.I.3    Lee, M.K.4    Pennil, C.C.5    Rendi, M.H.6
  • 19
    • 84878129623 scopus 로고    scopus 로고
    • Autophagy opposes p53-mediated tumor barrier to facilitate tumorigenesis in a model of PALB2-associated hereditary breast cancer
    • Huo Y, Cai H, Teplova I, Bowman-Colin C, Chen G, Price S et al. Autophagy opposes p53-mediated tumor barrier to facilitate tumorigenesis in a model of PALB2-associated hereditary breast cancer. Cancer Discov 2013; 3: 894-907.
    • (2013) Cancer Discov , vol.3 , pp. 894-907
    • Huo, Y.1    Cai, H.2    Teplova, I.3    Bowman-Colin, C.4    Chen, G.5    Price, S.6
  • 20
    • 84939175214 scopus 로고    scopus 로고
    • PARP inhibitors in the management of breast cancer: Current data and future prospects
    • Livraghi L, Garber JE. PARP inhibitors in the management of breast cancer: Current data and future prospects. BMC Med 2015; 13: 188.
    • (2015) BMC Med , vol.13 , pp. 188
    • Livraghi, L.1    Garber, J.E.2
  • 22
    • 84984874836 scopus 로고    scopus 로고
    • Interaction with PALB2 is essential for maintenance of genomic integrity by BRCA2
    • Hartford SA, Chittela R, Ding X, Vyas A, Martin B, Burkett S et al. Interaction with PALB2 is essential for maintenance of genomic integrity by BRCA2. PLoS Genet 2016; 12: E1006236.
    • (2016) PLoS Genet , vol.12 , pp. E1006236
    • Hartford, S.A.1    Chittela, R.2    Ding, X.3    Vyas, A.4    Martin, B.5    Burkett, S.6
  • 23
    • 84906860667 scopus 로고    scopus 로고
    • Male fertility defect associated with disrupted BRCA1-PALB2 interaction in mice
    • Simhadri S, Peterson S, Patel DS, Huo Y, Cai H, Bowman-Colin C et al. Male fertility defect associated with disrupted BRCA1-PALB2 interaction in mice. The J Biol Chem 2014; 289: 24617-24629.
    • (2014) The J Biol Chem , vol.289 , pp. 24617-24629
    • Simhadri, S.1    Peterson, S.2    Patel, D.S.3    Huo, Y.4    Cai, H.5    Bowman-Colin, C.6
  • 24
    • 84900794136 scopus 로고    scopus 로고
    • BRCA1 and estrogen/estrogen receptor in breast cancer Where they interact
    • Wang L, Di LJ. BRCA1 and estrogen/estrogen receptor in breast cancer: Where they interact? Int J Biol Sci 2014; 10: 566-575.
    • (2014) Int J Biol Sci , vol.10 , pp. 566-575
    • Wang, L.1    Di, L.J.2
  • 26
    • 84901687144 scopus 로고    scopus 로고
    • A recurrent neomorphic mutation in MYOD1 defines a clinically aggressive subset of embryonal rhabdomyosarcoma associated with PI3K-AKT pathway mutations
    • Kohsaka S, Shukla N, Ameur N, Ito T, Ng CK, Wang L et al. A recurrent neomorphic mutation in MYOD1 defines a clinically aggressive subset of embryonal rhabdomyosarcoma associated with PI3K-AKT pathway mutations. Nat Genet 2014; 46: 595-600.
    • (2014) Nat Genet , vol.46 , pp. 595-600
    • Kohsaka, S.1    Shukla, N.2    Ameur, N.3    Ito, T.4    Ng, C.K.5    Wang, L.6
  • 29
    • 67649884743 scopus 로고    scopus 로고
    • Fast and accurate short read alignment with Burrows-Wheeler transform
    • Li H, Durbin R. Fast and accurate short read alignment with Burrows-Wheeler transform. Bioinformatics 2009; 25: 1754-1760.
    • (2009) Bioinformatics , vol.25 , pp. 1754-1760
    • Li, H.1    Durbin, R.2
  • 30
    • 77956295988 scopus 로고    scopus 로고
    • The Genome analysis toolkit: A mapreduce framework for analyzing nextgeneration DNA sequencing data
    • McKenna A, Hanna M, Banks E, Sivachenko A, Cibulskis K, Kernytsky A et al. The Genome analysis toolkit: A mapreduce framework for analyzing nextgeneration DNA sequencing data. Genome Res 2010; 20: 1297-1303.
    • (2010) Genome Res , vol.20 , pp. 1297-1303
    • McKenna, A.1    Hanna, M.2    Banks, E.3    Sivachenko, A.4    Cibulskis, K.5    Kernytsky, A.6
  • 32
    • 84864153492 scopus 로고    scopus 로고
    • Strelka: Accurate somatic small-variant calling from sequenced tumor-normal sample pairs
    • Saunders CT, Wong WS, Swamy S, Becq J, Murray LJ, Cheetham RK. Strelka: Accurate somatic small-variant calling from sequenced tumor-normal sample pairs. Bioinformatics 2012; 28: 1811-1817.
    • (2012) Bioinformatics , vol.28 , pp. 1811-1817
    • Saunders, C.T.1    Wong, W.S.2    Swamy, S.3    Becq, J.4    Murray, L.J.5    Cheetham, R.K.6
  • 33
    • 84863229597 scopus 로고    scopus 로고
    • VarScan 2: Somatic mutation and copy number alteration discovery in cancer by exome sequencing
    • Koboldt DC, Zhang Q, Larson DE, Shen D, McLellan MD, Lin L et al. VarScan 2: Somatic mutation and copy number alteration discovery in cancer by exome sequencing. Genome Res 2012; 22: 568-576.
    • (2012) Genome Res , vol.22 , pp. 568-576
    • Koboldt, D.C.1    Zhang, Q.2    De, L.3    Shen, D.4    McLellan, M.D.5    Lin, L.6
  • 34
    • 84988924813 scopus 로고    scopus 로고
    • FACETS: Allele-specific copy number and clonal heterogeneity analysis tool for high-throughput DNA sequencing
    • Shen R, Seshan VE. FACETS: Allele-specific copy number and clonal heterogeneity analysis tool for high-throughput DNA sequencing. Nucleic Acids Res 2016; 44: E131.
    • (2016) Nucleic Acids Res , vol.44 , pp. E131
    • Shen, R.1    Seshan, V.E.2
  • 38
    • 77955151784 scopus 로고    scopus 로고
    • MutationTaster evaluates disease-causing potential of sequence alterations
    • Schwarz JM, Rodelsperger C, Schuelke M, Seelow D. MutationTaster evaluates disease-causing potential of sequence alterations. Nat Methods 2010; 7: 575-576.
    • (2010) Nat Methods , vol.7 , pp. 575-576
    • Schwarz, J.M.1    Rodelsperger, C.2    Schuelke, M.3    Seelow, D.4
  • 39
    • 69249115697 scopus 로고    scopus 로고
    • Cancer-specific high-throughput annotation of somatic mutations: Computational prediction of driver missense mutations
    • Carter H, Chen S, Isik L, Tyekucheva S, Velculescu VE, Kinzler KW et al. Cancer-specific high-throughput annotation of somatic mutations: Computational prediction of driver missense mutations. Cancer Res 2009; 69: 6660-6667.
    • (2009) Cancer Res , vol.69 , pp. 6660-6667
    • Carter, H.1    Chen, S.2    Isik, L.3    Tyekucheva, S.4    Velculescu, V.E.5    Kinzler, K.W.6
  • 40
    • 84871578629 scopus 로고    scopus 로고
    • Predicting the functional, molecular, and phenotypic consequences of amino acid substitutions using hidden Markov models
    • Shihab HA, Gough J, Cooper DN, Stenson PD, Barker GL, Edwards KJ et al. Predicting the functional, molecular, and phenotypic consequences of amino acid substitutions using hidden Markov models. Hum Mutat 2013; 34: 57-65.
    • (2013) Hum Mutat , vol.34 , pp. 57-65
    • Shihab, H.A.1    Gough, J.2    Cooper, D.N.3    Stenson, P.D.4    Barker, G.L.5    Edwards, K.J.6
  • 41
    • 84885735554 scopus 로고    scopus 로고
    • Mutational landscape and significance across 12 major cancer types
    • Kandoth C, McLellan MD, Vandin F, Ye K, Niu B, Lu C et al. Mutational landscape and significance across 12 major cancer types. Nature 2013; 502: 333-339.
    • (2013) Nature , vol.502 , pp. 333-339
    • Kandoth, C.1    McLellan, M.D.2    Vandin, F.3    Ye, K.4    Niu, B.5    Lu, C.6
  • 44
    • 84892585845 scopus 로고    scopus 로고
    • OmicCircos: A simpleto-use r package for the circular visualization of multidimensional omics data
    • Hu Y, Yan C, Hsu CH, Chen QR, Niu K, Komatsoulis GA et al. OmicCircos: A simpleto-use r package for the circular visualization of multidimensional omics data. Cancer Inform 2014; 13: 13-20.
    • (2014) Cancer Inform , vol.13 , pp. 13-20
    • Hu, Y.1    Yan, C.2    Ch, H.3    Chen, Q.R.4    Niu, K.5    Komatsoulis, G.A.6
  • 47
    • 84877028141 scopus 로고    scopus 로고
    • Comprehensive molecular portraits of human breast tumours
    • Cancer Genome Atlas Network
    • Cancer Genome Atlas Network. Comprehensive molecular portraits of human breast tumours. Nature 2012; 490: 61-70.
    • (2012) Nature , vol.490 , pp. 61-70
  • 48
    • 42949174531 scopus 로고    scopus 로고
    • Analysis of the gene coding for the BRCA2-interacting protein PALB2 in hereditary prostate cancer
    • Tischkowitz M, Sabbaghian N, Ray AM, Lange EM, Foulkes WD, Cooney KA. Analysis of the gene coding for the BRCA2-interacting protein PALB2 in hereditary prostate cancer. Prostate 2008; 68: 675-678.
    • (2008) Prostate , vol.68 , pp. 675-678
    • Tischkowitz, M.1    Sabbaghian, N.2    Ray, A.M.3    Lange, E.M.4    Foulkes, W.D.5    Cooney, K.A.6
  • 50
    • 84921919715 scopus 로고    scopus 로고
    • Mutation screening of PALB2 in clinically ascertained families from the Breast Cancer Family Registry
    • Nguyen-Dumont T, Hammet F, Mahmoodi M, Tsimiklis H, Teo ZL, Li R et al. Mutation screening of PALB2 in clinically ascertained families from the Breast Cancer Family Registry. Breast Cancer Res Treat 2015; 149: 547-554.
    • (2015) Breast Cancer Res Treat , vol.149 , pp. 547-554
    • Nguyen-Dumont, T.1    Hammet, F.2    Mahmoodi, M.3    Tsimiklis, H.4    Teo, Z.L.5    Li, R.6
  • 51
    • 84857368978 scopus 로고    scopus 로고
    • Novel germline PALB2 truncating mutations in African American breast cancer patients
    • Zheng Y, Zhang J, Niu Q, Huo D, Olopade OI. Novel germline PALB2 truncating mutations in African American breast cancer patients. Cancer 2012; 118: 1362-1370.
    • (2012) Cancer , vol.118 , pp. 1362-1370
    • Zheng, Y.1    Zhang, J.2    Niu, Q.3    Huo, D.4    Olopade, O.I.5
  • 54
    • 84880729402 scopus 로고    scopus 로고
    • Analysis of PALB2 gene in BRCA1/BRCA2 negative Spanish hereditary breast/ovarian cancer families with pancreatic cancer cases
    • Blanco A, de la Hoya M, Osorio A, Diez O, Miramar MD, Infante M et al. Analysis of PALB2 gene in BRCA1/BRCA2 negative Spanish hereditary breast/ovarian cancer families with pancreatic cancer cases. PLoS One 2013; 8: E67538.
    • (2013) PLoS One , vol.8 , pp. E67538
    • Blanco, A.1    Dela Hoya, M.2    Osorio, A.3    Diez, O.4    Miramar, M.D.5    Infante, M.6
  • 55
    • 84862776557 scopus 로고    scopus 로고
    • Rare germline mutations in PALB2 and breast cancer risk: A population-based study
    • Tischkowitz M, Capanu M, Sabbaghian N, Li L, Liang X, Valleé MP et al. Rare germline mutations in PALB2 and breast cancer risk: A population-based study. Hum Mutat 2012; 33: 674-680.
    • (2012) Hum Mutat , vol.33 , pp. 674-680
    • Tischkowitz, M.1    Capanu, M.2    Sabbaghian, N.3    Li, L.4    Liang, X.5    Valleé, M.P.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.