메뉴 건너뛰기




Volumn 14, Issue 12, 2016, Pages 1706-1719.e5

Use of Proton Pump Inhibitors and Risks of Fundic Gland Polyps and Gastric Cancer: Systematic Review and Meta-analysis

Author keywords

Acid Suppressive Drug; Neoplasm; Side Effect; Stomach Carcinoma

Indexed keywords

PROTON PUMP INHIBITOR;

EID: 85015649552     PISSN: 15423565     EISSN: 15427714     Source Type: Journal    
DOI: 10.1016/j.cgh.2016.05.018     Document Type: Review
Times cited : (152)

References (69)
  • 1
    • 60749128080 scopus 로고    scopus 로고
    • Pharmacology of proton pump inhibitors
    • 1 Shin, J.M., Sachs, G., Pharmacology of proton pump inhibitors. Curr Gastroenterol Rep 10 (2008), 528–534.
    • (2008) Curr Gastroenterol Rep , vol.10 , pp. 528-534
    • Shin, J.M.1    Sachs, G.2
  • 2
    • 0028035385 scopus 로고
    • Frequency, location, and age and sex distribution of various types of gastric polyp
    • 2 Stolte, M., Sticht, T., Eidt, S., et al. Frequency, location, and age and sex distribution of various types of gastric polyp. Endoscopy 26 (1994), 659–665.
    • (1994) Endoscopy , vol.26 , pp. 659-665
    • Stolte, M.1    Sticht, T.2    Eidt, S.3
  • 3
    • 0029815302 scopus 로고    scopus 로고
    • Gastric fundic gland polyps: a morphological study including mucin histochemistry, stereometry, and MIB-1 immunohistochemistry
    • 3 Odze, R.D., Marcial, M.A., Antonioli, D., Gastric fundic gland polyps: a morphological study including mucin histochemistry, stereometry, and MIB-1 immunohistochemistry. Hum Pathol 27 (1996), 896–903.
    • (1996) Hum Pathol , vol.27 , pp. 896-903
    • Odze, R.D.1    Marcial, M.A.2    Antonioli, D.3
  • 4
    • 0020507229 scopus 로고
    • Cystic ‘hamartomatous’ gastric polyps: a disorder of oxyntic glands
    • 4 Sipponen, P., Laxen, F., Seppala, K., Cystic ‘hamartomatous’ gastric polyps: a disorder of oxyntic glands. Histopathology 7 (1983), 729–737.
    • (1983) Histopathology , vol.7 , pp. 729-737
    • Sipponen, P.1    Laxen, F.2    Seppala, K.3
  • 5
    • 0022455296 scopus 로고
    • The histopathology of fundic gland polyps of the stomach
    • 5 Lee, R.G., Burt, R.W., The histopathology of fundic gland polyps of the stomach. Am J Clin Pathol 86 (1986), 498–503.
    • (1986) Am J Clin Pathol , vol.86 , pp. 498-503
    • Lee, R.G.1    Burt, R.W.2
  • 6
    • 0027215643 scopus 로고
    • Incidence of fundic gland polyps in patients without familial adenomatous polyposis
    • 6 Kinoshita, Y., Tojo, M., Yano, T., et al. Incidence of fundic gland polyps in patients without familial adenomatous polyposis. Gastrointest Endosc 39 (1993), 161–163.
    • (1993) Gastrointest Endosc , vol.39 , pp. 161-163
    • Kinoshita, Y.1    Tojo, M.2    Yano, T.3
  • 7
    • 0022379250 scopus 로고
    • Natural history of fundic gland polyposis in patients with familial adenomatosis coli/Gardner's syndrome
    • 7 Iida, M., Yao, T., Itoh, H., et al. Natural history of fundic gland polyposis in patients with familial adenomatosis coli/Gardner's syndrome. Gastroenterology 89 (1985), 1021–1025.
    • (1985) Gastroenterology , vol.89 , pp. 1021-1025
    • Iida, M.1    Yao, T.2    Itoh, H.3
  • 8
    • 0026801066 scopus 로고
    • Gastric polyposis: onset during long-term therapy with omeprazole
    • 8 Graham, J., Gastric polyposis: onset during long-term therapy with omeprazole. Med J Aust 157 (1992), 287–288.
    • (1992) Med J Aust , vol.157 , pp. 287-288
    • Graham, J.1
  • 9
    • 0028968418 scopus 로고
    • Observation of gastric glandular cysts in the corpus mucosa of the stomach under omeprazole treatment
    • 9 Stolte, M., Bethke, B., Seifert, E., et al. Observation of gastric glandular cysts in the corpus mucosa of the stomach under omeprazole treatment. Z Gastroenterol 33 (1995), 146–149.
    • (1995) Z Gastroenterol , vol.33 , pp. 146-149
    • Stolte, M.1    Bethke, B.2    Seifert, E.3
  • 10
    • 0030664139 scopus 로고    scopus 로고
    • Fundic gland polyps: three other case reports suggesting a possible association with acid suppressing therapy
    • 10 Van Vlierberghe, H., De Vos, M., De Cock, G., et al. Fundic gland polyps: three other case reports suggesting a possible association with acid suppressing therapy. Acta Gastroenterol Belg 60 (1997), 240–242.
    • (1997) Acta Gastroenterol Belg , vol.60 , pp. 240-242
    • Van Vlierberghe, H.1    De Vos, M.2    De Cock, G.3
  • 11
    • 0036550786 scopus 로고    scopus 로고
    • Spontaneous resolution of multiple fundic gland polyps after cessation of treatment with lansoprazole and Nissen fundoplication: a case report
    • 11 Kazantsev, G.B., Schwesinger, W.H., Heim-Hall, J., Spontaneous resolution of multiple fundic gland polyps after cessation of treatment with lansoprazole and Nissen fundoplication: a case report. Gastrointest Endosc 55 (2002), 600–602.
    • (2002) Gastrointest Endosc , vol.55 , pp. 600-602
    • Kazantsev, G.B.1    Schwesinger, W.H.2    Heim-Hall, J.3
  • 12
    • 27144433180 scopus 로고    scopus 로고
    • Gastric fundal polyps with cellular atypia in a patient using esomeprazole (Nexium)
    • 12 Flick, A.L., Gastric fundal polyps with cellular atypia in a patient using esomeprazole (Nexium). Dig Dis Sci 50 (2005), 2100–2102.
    • (2005) Dig Dis Sci , vol.50 , pp. 2100-2102
    • Flick, A.L.1
  • 13
    • 58149333895 scopus 로고    scopus 로고
    • Spontaneous resolution of multiple fundic gland polyps after cessation of treatment with omeprazole
    • 13 Kim, J.S., Chae, H.S., Kim, H.K., et al. Spontaneous resolution of multiple fundic gland polyps after cessation of treatment with omeprazole. Korean J Gastroenterol 51 (2008), 305–308.
    • (2008) Korean J Gastroenterol , vol.51 , pp. 305-308
    • Kim, J.S.1    Chae, H.S.2    Kim, H.K.3
  • 14
    • 76749149168 scopus 로고    scopus 로고
    • A report of gastric fundic gland polyps
    • 14 Spiegel, A., Stein, P., Patel, M., et al. A report of gastric fundic gland polyps. Gastroenterol Hepatol 6 (2010), 45–48.
    • (2010) Gastroenterol Hepatol , vol.6 , pp. 45-48
    • Spiegel, A.1    Stein, P.2    Patel, M.3
  • 15
    • 84857522089 scopus 로고    scopus 로고
    • Massive fundic gland polyposis caused by chronic proton pump inhibitor therapy. [Hungarian] Tartos protonpumpagatlo kezeles hatasara kialakulo massziv fundusmirigy-polyposis
    • 15 Hegedus, I., Csizmadia, C., Lomb, Z., et al. Massive fundic gland polyposis caused by chronic proton pump inhibitor therapy. [Hungarian] Tartos protonpumpagatlo kezeles hatasara kialakulo massziv fundusmirigy-polyposis. Orv Hetil 153 (2012), 351–356.
    • (2012) Orv Hetil , vol.153 , pp. 351-356
    • Hegedus, I.1    Csizmadia, C.2    Lomb, Z.3
  • 16
    • 0034495101 scopus 로고    scopus 로고
    • Fundic gland polyps in familial adenomatous polyposis: neoplasms with frequent somatic adenomatous polyposis coli gene alterations
    • 16 Abraham, S.C., Nobukawa, B., Giardiello, F.M., et al. Fundic gland polyps in familial adenomatous polyposis: neoplasms with frequent somatic adenomatous polyposis coli gene alterations. Am J Pathol 157 (2000), 747–754.
    • (2000) Am J Pathol , vol.157 , pp. 747-754
    • Abraham, S.C.1    Nobukawa, B.2    Giardiello, F.M.3
  • 17
    • 0035103118 scopus 로고    scopus 로고
    • Sporadic fundic gland polyps: common gastric polyps arising through activating mutations in the beta-catenin gene
    • 17 Abraham, S.C., Nobukawa, B., Giardiello, F.M., et al. Sporadic fundic gland polyps: common gastric polyps arising through activating mutations in the beta-catenin gene. Am J Pathol 158 (2001), 1005–1010.
    • (2001) Am J Pathol , vol.158 , pp. 1005-1010
    • Abraham, S.C.1    Nobukawa, B.2    Giardiello, F.M.3
  • 18
    • 66949173716 scopus 로고    scopus 로고
    • The current spectrum of gastric polyps: A 1-year national study of over 120,000 patients
    • 18 Carmack, S.W., Genta, R.M., Schuler, C.M., et al. The current spectrum of gastric polyps: A 1-year national study of over 120,000 patients. Am J Gastroenterol 104 (2009), 1524–1532.
    • (2009) Am J Gastroenterol , vol.104 , pp. 1524-1532
    • Carmack, S.W.1    Genta, R.M.2    Schuler, C.M.3
  • 19
    • 0031885979 scopus 로고    scopus 로고
    • Dysplasia and dysregulation of proliferation in foveolar and surface epithelia of fundic gland polyps from patients with familial adenomatous polyposis
    • 19 Wu, T.T., Kornacki, S., Rashid, A., et al. Dysplasia and dysregulation of proliferation in foveolar and surface epithelia of fundic gland polyps from patients with familial adenomatous polyposis. Am J Surg Pathol 22 (1998), 293–298.
    • (1998) Am J Surg Pathol , vol.22 , pp. 293-298
    • Wu, T.T.1    Kornacki, S.2    Rashid, A.3
  • 20
    • 0842286965 scopus 로고    scopus 로고
    • High-grade dysplasia in sporadic fundic gland polyps: a case report and review of the literature
    • 20 Jalving, M., Koornstra, J.J., Gotz, J.M., et al. High-grade dysplasia in sporadic fundic gland polyps: a case report and review of the literature. Eur J Gastroenterol Hepatol 15 (2003), 1229–1233.
    • (2003) Eur J Gastroenterol Hepatol , vol.15 , pp. 1229-1233
    • Jalving, M.1    Koornstra, J.J.2    Gotz, J.M.3
  • 21
    • 0023035760 scopus 로고
    • Enterochromaffin-like cell carcinoids of gastric mucosa in rats after life-long inhibition of gastric secretion
    • 21 Havu, N., Enterochromaffin-like cell carcinoids of gastric mucosa in rats after life-long inhibition of gastric secretion. Digestion 35 (1986), 42–55.
    • (1986) Digestion , vol.35 , pp. 42-55
    • Havu, N.1
  • 22
    • 70349324586 scopus 로고    scopus 로고
    • Long-term safety concerns with proton pump inhibitors
    • 22 Ali, T., Roberts, D.N., Tierney, W.M., Long-term safety concerns with proton pump inhibitors. Am J Med 122 (2009), 896–903.
    • (2009) Am J Med , vol.122 , pp. 896-903
    • Ali, T.1    Roberts, D.N.2    Tierney, W.M.3
  • 23
    • 7344222764 scopus 로고    scopus 로고
    • Hypergastrinaemia during long-term omeprazole therapy: influences of vagal nerve function, gastric emptying and Helicobacter pylori infection
    • 23 Schenk, B.E., Kuipers, E.J., Klinkenberg-Knol, E.C., et al. Hypergastrinaemia during long-term omeprazole therapy: influences of vagal nerve function, gastric emptying and Helicobacter pylori infection. Aliment Pharmacol Ther 12 (1998), 605–612.
    • (1998) Aliment Pharmacol Ther , vol.12 , pp. 605-612
    • Schenk, B.E.1    Kuipers, E.J.2    Klinkenberg-Knol, E.C.3
  • 24
    • 0028915876 scopus 로고
    • Effect of Helicobacter pylori status on intragastric pH during treatment with omeprazole
    • 24 Verdu, E.F., Armstrong, D., Fraser, R., et al. Effect of Helicobacter pylori status on intragastric pH during treatment with omeprazole. Gut 36 (1995), 539–543.
    • (1995) Gut , vol.36 , pp. 539-543
    • Verdu, E.F.1    Armstrong, D.2    Fraser, R.3
  • 25
    • 0032948187 scopus 로고    scopus 로고
    • Helicobacter pylori infection potentiates the inhibition of gastric acid secretion by omeprazole
    • 25 Gillen, D., Wirz, A.A., Neithercut, W.D., et al. Helicobacter pylori infection potentiates the inhibition of gastric acid secretion by omeprazole. Gut 44 (1999), 468–475.
    • (1999) Gut , vol.44 , pp. 468-475
    • Gillen, D.1    Wirz, A.A.2    Neithercut, W.D.3
  • 26
    • 0035115434 scopus 로고    scopus 로고
    • Non-Helicobacter pylori bacterial flora during acid-suppressive therapy: Differential findings in gastric juice and gastric mucosa
    • 26 Sanduleanu, S., Jonkers, D., De Bruine, A., et al. Non-Helicobacter pylori bacterial flora during acid-suppressive therapy: Differential findings in gastric juice and gastric mucosa. Aliment Pharmacol Ther 15 (2001), 379–388.
    • (2001) Aliment Pharmacol Ther , vol.15 , pp. 379-388
    • Sanduleanu, S.1    Jonkers, D.2    De Bruine, A.3
  • 27
    • 0034920472 scopus 로고    scopus 로고
    • Double gastric infection with Helicobacter pylori and non-Helicobacter pylori bacteria during acid-suppressive therapy: increase of pro-inflammatory cytokines and development of atrophic gastritis
    • 27 Sanduleanu, S., Jonkers, D., De Bruine, A., et al. Double gastric infection with Helicobacter pylori and non-Helicobacter pylori bacteria during acid-suppressive therapy: increase of pro-inflammatory cytokines and development of atrophic gastritis. Aliment Pharmacol Ther 15 (2001), 1163–1175.
    • (2001) Aliment Pharmacol Ther , vol.15 , pp. 1163-1175
    • Sanduleanu, S.1    Jonkers, D.2    De Bruine, A.3
  • 28
    • 84941711617 scopus 로고    scopus 로고
    • Incidence of gastric cancer among patients with gastric precancerous lesions: observational cohort study in a low risk Western population
    • 28 Song, H., Ekheden, I.G., Zheng, Z., et al. Incidence of gastric cancer among patients with gastric precancerous lesions: observational cohort study in a low risk Western population. BMJ, 351, 2015, h3867.
    • (2015) BMJ , vol.351 , pp. h3867
    • Song, H.1    Ekheden, I.G.2    Zheng, Z.3
  • 29
    • 78049354889 scopus 로고    scopus 로고
    • Helicobacter pylori and Gastric Cancer: Factors That Modulate Disease Risk
    • 29 Wroblewski, L.E., Peek, R.M., Wilson, K.T., Helicobacter pylori and Gastric Cancer: Factors That Modulate Disease Risk. Clin Microbiol Rev 23 (2010), 713–739.
    • (2010) Clin Microbiol Rev , vol.23 , pp. 713-739
    • Wroblewski, L.E.1    Peek, R.M.2    Wilson, K.T.3
  • 31
    • 85020322154 scopus 로고    scopus 로고
    • editors. The Newcastle-Ottawa Scale (NOS) for assessing the quality of nonrandomised studies in meta-analyses. 2012. Available at: Accessed December 25, 2015.
    • 31 Wells GA, Shea B, O'Connell D, et al., editors. The Newcastle-Ottawa Scale (NOS) for assessing the quality of nonrandomised studies in meta-analyses. 2012. Available at: http://www.ohri.ca/programs/clinical_epidemiology/oxford.asp. Accessed December 25, 2015.
    • Wells, G.A.1    Shea, B.2    O'Connell, D.3
  • 32
    • 0037098199 scopus 로고    scopus 로고
    • Quantifying heterogeneity in a meta-analysis
    • 32 Higgins, J., Thompson, S.G., Quantifying heterogeneity in a meta-analysis. Stat Med 21 (2002), 1539–1558.
    • (2002) Stat Med , vol.21 , pp. 1539-1558
    • Higgins, J.1    Thompson, S.G.2
  • 33
    • 0030922816 scopus 로고    scopus 로고
    • Bias in meta-analysis detected by a simple, graphical test
    • 33 Egger, M., Smith, G.D., Schneider, M., et al. Bias in meta-analysis detected by a simple, graphical test. BMJ 315 (1997), 629–634.
    • (1997) BMJ , vol.315 , pp. 629-634
    • Egger, M.1    Smith, G.D.2    Schneider, M.3
  • 34
    • 77958110812 scopus 로고    scopus 로고
    • Conducting meta-analyses in R with the metafor package
    • 34 Viechtbauer, W., Conducting meta-analyses in R with the metafor package. J Stat Softw 36 (2010), 1–48.
    • (2010) J Stat Softw , vol.36 , pp. 1-48
    • Viechtbauer, W.1
  • 35
    • 69149107165 scopus 로고    scopus 로고
    • Preferred reporting items for systematic reviews and meta-analyses: the PRISMA statement
    • 35 Moher, D., Liberati, A., Tetzlaff, J., et al. Preferred reporting items for systematic reviews and meta-analyses: the PRISMA statement. Ann Intern Med 151 (2009), 264–269.
    • (2009) Ann Intern Med , vol.151 , pp. 264-269
    • Moher, D.1    Liberati, A.2    Tetzlaff, J.3
  • 36
    • 0034685429 scopus 로고    scopus 로고
    • Meta-analysis of observational studies in epidemiology: a proposal for reporting
    • 36 Stroup, D.F., Berlin, J.A., Morton, S.C., et al. Meta-analysis of observational studies in epidemiology: a proposal for reporting. JAMA 283 (2000), 2008–2012.
    • (2000) JAMA , vol.283 , pp. 2008-2012
    • Stroup, D.F.1    Berlin, J.A.2    Morton, S.C.3
  • 37
    • 71949085770 scopus 로고    scopus 로고
    • Safety profile of dexlansoprazole MR, a proton pump inhibitor with a novel dual delayed release formulation: Global clinical trial experience
    • 37 Peura, D.A., Metz, D.C., Dabholkar, A.H., et al. Safety profile of dexlansoprazole MR, a proton pump inhibitor with a novel dual delayed release formulation: Global clinical trial experience. Aliment Pharmacol Ther 30 (2009), 1010–1021.
    • (2009) Aliment Pharmacol Ther , vol.30 , pp. 1010-1021
    • Peura, D.A.1    Metz, D.C.2    Dabholkar, A.H.3
  • 38
    • 0031785024 scopus 로고    scopus 로고
    • Proton pump inhibitor-associated gastric polyps: A retrospective analysis of their frequency, and endoscopic, histologic, and ultrastructural characteristics
    • 38 Choudhry, U., Boyce, H.W. Jr., Coppola, D., Proton pump inhibitor-associated gastric polyps: A retrospective analysis of their frequency, and endoscopic, histologic, and ultrastructural characteristics. Am J Clin Pathol 110 (1998), 615–621.
    • (1998) Am J Clin Pathol , vol.110 , pp. 615-621
    • Choudhry, U.1    Boyce, H.W.2    Coppola, D.3
  • 39
    • 0035735728 scopus 로고    scopus 로고
    • Fundic gland polyps are not induced by proton pump inhibitor therapy
    • 39 Vieth, M., Stolte, M., Fundic gland polyps are not induced by proton pump inhibitor therapy. Am J Clin Pathol 116 (2001), 716–720.
    • (2001) Am J Clin Pathol , vol.116 , pp. 716-720
    • Vieth, M.1    Stolte, M.2
  • 40
    • 33749998082 scopus 로고    scopus 로고
    • Increased risk of fundic gland polyps during long-term proton pump inhibitor therapy
    • 40 Jalving, M., Koornstra, J.J., Wesseling, J., et al. Increased risk of fundic gland polyps during long-term proton pump inhibitor therapy. Aliment Pharmacol Ther 24 (2006), 1341–1348.
    • (2006) Aliment Pharmacol Ther , vol.24 , pp. 1341-1348
    • Jalving, M.1    Koornstra, J.J.2    Wesseling, J.3
  • 41
    • 70450247184 scopus 로고    scopus 로고
    • Chronic proton pump inhibitor therapy associated with increased development of fundic gland polyps
    • 41 Ally, M.R., Veerappan, G.R., Maydonovitch, C.L., et al. Chronic proton pump inhibitor therapy associated with increased development of fundic gland polyps. Dig Dis Sci 54 (2009), 2617–2622.
    • (2009) Dig Dis Sci , vol.54 , pp. 2617-2622
    • Ally, M.R.1    Veerappan, G.R.2    Maydonovitch, C.L.3
  • 42
    • 76549120019 scopus 로고    scopus 로고
    • Influence of Proton Pump Inhibitor Use in Gastrointestinal Polyps
    • 42 Hsu, W.H., Wu, I.C., Kuo, C.H., et al. Influence of Proton Pump Inhibitor Use in Gastrointestinal Polyps. Kaohsiung J Med Sci 26 (2010), 76–83.
    • (2010) Kaohsiung J Med Sci , vol.26 , pp. 76-83
    • Hsu, W.H.1    Wu, I.C.2    Kuo, C.H.3
  • 43
    • 79959723368 scopus 로고    scopus 로고
    • Fundic gland polyps and association with proton pump inhibitor intake: A prospective study in 1,780 endoscopies
    • 43 Zelter, A., Fernandez, J.L., Bilder, C., et al. Fundic gland polyps and association with proton pump inhibitor intake: A prospective study in 1,780 endoscopies. Dig Dis Sci 56 (2011), 1743–1748.
    • (2011) Dig Dis Sci , vol.56 , pp. 1743-1748
    • Zelter, A.1    Fernandez, J.L.2    Bilder, C.3
  • 44
    • 84897943542 scopus 로고    scopus 로고
    • Sporadic fundic gland polyps are not associated with proton pump inhibitors therapy but negatively correlate with Helicobacter pylori infection in China
    • 44 Cao, H.L., Qu, R., Zhang, Z.H., et al. Sporadic fundic gland polyps are not associated with proton pump inhibitors therapy but negatively correlate with Helicobacter pylori infection in China. Chin Med J (Engl) 127 (2014), 1239–1243.
    • (2014) Chin Med J (Engl) , vol.127 , pp. 1239-1243
    • Cao, H.L.1    Qu, R.2    Zhang, Z.H.3
  • 45
    • 65549096192 scopus 로고    scopus 로고
    • Proton pump inhibitors and risk of gastric cancer: A population-based cohort study
    • 45 Poulsen, A.H., Christensen, S., McLaughlin, J.K., et al. Proton pump inhibitors and risk of gastric cancer: A population-based cohort study. Br J Cancer 100 (2009), 1503–1507.
    • (2009) Br J Cancer , vol.100 , pp. 1503-1507
    • Poulsen, A.H.1    Christensen, S.2    McLaughlin, J.K.3
  • 46
    • 33750352352 scopus 로고    scopus 로고
    • Gastric acid suppression and risk of oesophageal and gastric adenocarcinoma: A nested case control study in the UK
    • 46 Garcia Rodriguez, L.A., Lagergren, J., Lindblad, M., Gastric acid suppression and risk of oesophageal and gastric adenocarcinoma: A nested case control study in the UK. Gut 55 (2006), 1538–1544.
    • (2006) Gut , vol.55 , pp. 1538-1544
    • Garcia Rodriguez, L.A.1    Lagergren, J.2    Lindblad, M.3
  • 47
    • 34547613899 scopus 로고    scopus 로고
    • Subsite-specific risk factors for esophageal and gastric adenocarcinoma
    • 47 Crane, S.J., Locke, I.G.R., Harmsen, W.S., et al. Subsite-specific risk factors for esophageal and gastric adenocarcinoma. Am J Gastroenterol 102 (2007), 1596–1602.
    • (2007) Am J Gastroenterol , vol.102 , pp. 1596-1602
    • Crane, S.J.1    Locke, I.G.R.2    Harmsen, W.S.3
  • 48
    • 47649114119 scopus 로고    scopus 로고
    • Association between use of acid-suppressive drugs and risk of gastric cancer: A nested case-control study
    • 48 Tamim, H., Duranceau, A., Chen, L.Q., et al. Association between use of acid-suppressive drugs and risk of gastric cancer: A nested case-control study. Drug Saf 31 (2008), 675–684.
    • (2008) Drug Saf , vol.31 , pp. 675-684
    • Tamim, H.1    Duranceau, A.2    Chen, L.Q.3
  • 49
    • 0030016192 scopus 로고    scopus 로고
    • Prevalence of fundic gland polyps in a western European population
    • 49 Dickey, W., Kenny, B.D., McConnell, J.B., Prevalence of fundic gland polyps in a western European population. J Clin Gastroenterol 23 (1996), 73–75.
    • (1996) J Clin Gastroenterol , vol.23 , pp. 73-75
    • Dickey, W.1    Kenny, B.D.2    McConnell, J.B.3
  • 50
    • 0031924492 scopus 로고    scopus 로고
    • Low prevalence of Helicobacter pylori infection in patients with hamartomatous fundic polyps
    • 50 Sakai, N., Tatsuta, M., Hirasawa, R., et al. Low prevalence of Helicobacter pylori infection in patients with hamartomatous fundic polyps. Dig Dis Sci 43 (1998), 766–772.
    • (1998) Dig Dis Sci , vol.43 , pp. 766-772
    • Sakai, N.1    Tatsuta, M.2    Hirasawa, R.3
  • 51
    • 0036839262 scopus 로고    scopus 로고
    • Regression of fundic gland polyps following acquisition of Helicobacter pylori
    • 51 Watanabe, N., Seno, H., Nakajima, T., et al. Regression of fundic gland polyps following acquisition of Helicobacter pylori. Gut 51 (2002), 742–745.
    • (2002) Gut , vol.51 , pp. 742-745
    • Watanabe, N.1    Seno, H.2    Nakajima, T.3
  • 52
    • 67949111273 scopus 로고    scopus 로고
    • No Association Between Gastric Fundic Gland Polyps and Gastrointestinal Neoplasia in a Study of Over 100,000 Patients
    • 52 Genta, R.M., Schuler, C.M., Robiou, C.I., et al. No Association Between Gastric Fundic Gland Polyps and Gastrointestinal Neoplasia in a Study of Over 100,000 Patients. Clin Gastroenterol Hepatol 7 (2009), 849–854.
    • (2009) Clin Gastroenterol Hepatol , vol.7 , pp. 849-854
    • Genta, R.M.1    Schuler, C.M.2    Robiou, C.I.3
  • 53
    • 0027259333 scopus 로고
    • Omeprazole and gastric polyposis in humans
    • 53 Graham, J.R., Omeprazole and gastric polyposis in humans. Gastroenterology, 104, 1993, 1584.
    • (1993) Gastroenterology , vol.104 , pp. 1584
    • Graham, J.R.1
  • 54
    • 4243392082 scopus 로고    scopus 로고
    • Gastric polyps and long-term omeprazole
    • 54 Collins, S., Tydd, T., Gastric polyps and long-term omeprazole. J Gastroenterol Hepatol, 13, 1998, A149.
    • (1998) J Gastroenterol Hepatol , vol.13 , pp. A149
    • Collins, S.1    Tydd, T.2
  • 55
    • 33750020247 scopus 로고    scopus 로고
    • Long-term use of omeprazole is associated with development of benign epithelial gastric polyps
    • 55 Mogadam, M., Houk, R., Long-term use of omeprazole is associated with development of benign epithelial gastric polyps. Am J Gastroenterol, 91, 1996, A151.
    • (1996) Am J Gastroenterol , vol.91 , pp. A151
    • Mogadam, M.1    Houk, R.2
  • 56
    • 4243924666 scopus 로고    scopus 로고
    • Fundic gland polyps and chronic PPI treatment: a prospective study
    • 56 Reekmans, A., Naegels, S., Urbain, D., Fundic gland polyps and chronic PPI treatment: a prospective study. Gastroenterology, 120, 2001, A244.
    • (2001) Gastroenterology , vol.120 , pp. A244
    • Reekmans, A.1    Naegels, S.2    Urbain, D.3
  • 57
    • 0029801308 scopus 로고    scopus 로고
    • Gastric epithelial polyps: a retrospective endoscopic study of 12974 symptomatic patients
    • 57 Archimandritis, A., Spiliadis, C., Tzivras, M., et al. Gastric epithelial polyps: a retrospective endoscopic study of 12974 symptomatic patients. Ital J Gastroenterol 28 (1996), 387–390.
    • (1996) Ital J Gastroenterol , vol.28 , pp. 387-390
    • Archimandritis, A.1    Spiliadis, C.2    Tzivras, M.3
  • 58
    • 0027374547 scopus 로고
    • Fundic gland polyps: prevalence and clinicopathologic features
    • 58 Marcial, M.A., Villafana, M., Hernandez-Denton, J., et al. Fundic gland polyps: prevalence and clinicopathologic features. Am J Gastroenterol 88 (1993), 1711–1713.
    • (1993) Am J Gastroenterol , vol.88 , pp. 1711-1713
    • Marcial, M.A.1    Villafana, M.2    Hernandez-Denton, J.3
  • 59
    • 0031595463 scopus 로고    scopus 로고
    • Histologic types and surveillance of gastric polyps: a seven year clinico-pathological study
    • 59 Papa, A., Cammarota, G., Tursi, A., et al. Histologic types and surveillance of gastric polyps: a seven year clinico-pathological study. Hepatogastroenterology 45 (1998), 579–582.
    • (1998) Hepatogastroenterology , vol.45 , pp. 579-582
    • Papa, A.1    Cammarota, G.2    Tursi, A.3
  • 60
    • 0003093603 scopus 로고
    • Fundic gland polyps in patients on long term omeprazole therapy: a light and electron microscopic study of the gastric mucosa
    • 60 Weinstein, W., Ang, S., Ippoliti, A., et al. Fundic gland polyps in patients on long term omeprazole therapy: a light and electron microscopic study of the gastric mucosa. Gastroenterology, 106, 1994, A210.
    • (1994) Gastroenterology , vol.106 , pp. A210
    • Weinstein, W.1    Ang, S.2    Ippoliti, A.3
  • 61
    • 0000660194 scopus 로고    scopus 로고
    • Fundic gland polyps: a comparison of the omeprazole-associated and the sporadic types
    • 61 Hirt, M., Lee, S., Weinstein, W., Fundic gland polyps: a comparison of the omeprazole-associated and the sporadic types. Gastroenterology, 110, 1996, A135.
    • (1996) Gastroenterology , vol.110 , pp. A135
    • Hirt, M.1    Lee, S.2    Weinstein, W.3
  • 62
    • 0036177452 scopus 로고    scopus 로고
    • Gastric polyps in pediatrics: an 18-year hospital-based analysis
    • 62 Attard, T.M., Yardley, J.H., Cuffari, C., Gastric polyps in pediatrics: an 18-year hospital-based analysis. Am J Gastroenterol 97 (2002), 298–301.
    • (2002) Am J Gastroenterol , vol.97 , pp. 298-301
    • Attard, T.M.1    Yardley, J.H.2    Cuffari, C.3
  • 63
    • 84877272906 scopus 로고    scopus 로고
    • Acid suppressive drugs and gastric cancer: A meta-analysis of observational studies
    • 63 Ahn, J.S., Eom, C.S., Jeon, C.Y., et al. Acid suppressive drugs and gastric cancer: A meta-analysis of observational studies. World J Gastroenterol 19 (2013), 2560–2568.
    • (2013) World J Gastroenterol , vol.19 , pp. 2560-2568
    • Ahn, J.S.1    Eom, C.S.2    Jeon, C.Y.3
  • 64
    • 0034695684 scopus 로고    scopus 로고
    • A H+-gated urea channel: the link between Helicobacter pylori urease and gastric colonization
    • 64 Weeks, D.L., Eskandari, S., Scott, D.R., et al. A H+-gated urea channel: the link between Helicobacter pylori urease and gastric colonization. Science 287 (2000), 482–485.
    • (2000) Science , vol.287 , pp. 482-485
    • Weeks, D.L.1    Eskandari, S.2    Scott, D.R.3
  • 65
    • 0029146892 scopus 로고
    • Increase of Helicobacter pylori-associated corpus gastritis during acid suppressive therapy: Implications for long-term safety
    • 65 Kuipers, E.J., Uyterlinde, A.M., Pena, A.S., et al. Increase of Helicobacter pylori-associated corpus gastritis during acid suppressive therapy: Implications for long-term safety. Am J Gastroenterol 90 (1995), 1401–1406.
    • (1995) Am J Gastroenterol , vol.90 , pp. 1401-1406
    • Kuipers, E.J.1    Uyterlinde, A.M.2    Pena, A.S.3
  • 66
    • 15844369552 scopus 로고    scopus 로고
    • Atrophic gastritis and Helicobacter pylori infection in patients with reflux esophagitis treated with omeprazole or fundoplication
    • 66 Kuipers, E.J., Lundell, L., Klinkenberg-Knol, E.C., et al. Atrophic gastritis and Helicobacter pylori infection in patients with reflux esophagitis treated with omeprazole or fundoplication. N Engl J Med 334 (1996), 1018–1022.
    • (1996) N Engl J Med , vol.334 , pp. 1018-1022
    • Kuipers, E.J.1    Lundell, L.2    Klinkenberg-Knol, E.C.3
  • 67
    • 33645006153 scopus 로고    scopus 로고
    • Changes of gastric mucosal architecture during long-term omeprazole therapy: results of a randomized clinical trial
    • 67 Lundell, L., Havu, N., Miettinen, P., et al. Changes of gastric mucosal architecture during long-term omeprazole therapy: results of a randomized clinical trial. Aliment Pharmacol Ther 23 (2006), 639–647.
    • (2006) Aliment Pharmacol Ther , vol.23 , pp. 639-647
    • Lundell, L.1    Havu, N.2    Miettinen, P.3
  • 68
    • 0035856021 scopus 로고    scopus 로고
    • Helicobacter pylori infection and the development of gastric cancer
    • 68 Uemura, N., Okamoto, S., Yamamoto, S., et al. Helicobacter pylori infection and the development of gastric cancer. N Engl J Med 345 (2001), 784–789.
    • (2001) N Engl J Med , vol.345 , pp. 784-789
    • Uemura, N.1    Okamoto, S.2    Yamamoto, S.3
  • 69
    • 70349386118 scopus 로고    scopus 로고
    • Clinical trial: the effects of the proton pump inhibitor dexlansoprazole MR on daytime and nighttime heartburn in patients with non-erosive reflux disease
    • 69 Fass, R., Chey, W.D., Zakko, S.F., et al. Clinical trial: the effects of the proton pump inhibitor dexlansoprazole MR on daytime and nighttime heartburn in patients with non-erosive reflux disease. Aliment Pharmacol Ther 29 (2009), 1261–1272.
    • (2009) Aliment Pharmacol Ther , vol.29 , pp. 1261-1272
    • Fass, R.1    Chey, W.D.2    Zakko, S.F.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.