Ribonucleic artefacts: Are some extracellular RNA discoveries driven by cell culture medium components?

Journal of Extracellular Vesicles

Volumn 6, Issue 1, 2017, Pages

  Tosar, Juan Pablo ^a,b   Cayota, Alfonso ^a,c   Eitan, Erez ^d   Halushka, Marc K ^e   Witwer, Kenneth W ^e  

^a INSTITUT PASTEUR DE MONTEVIDEO   (Uruguay)

^b UNIVERSIDAD DE LA REPÚBLICA   (Uruguay)

^c DEPARTAMENTO DE BIOQUÍMICA   (Uruguay)

^d NATIONAL INSTITUTE ON AGING   (United States)

^e JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Artefact; Cell culture; Contamination; Exosomes; Extracellular vesicles; MicroRNA; Microvesicles; RNA; Serum; Ultracentrifugation

Indexed keywords

MICRORNA; MICRORNA 122; MICRORNA 451A; UNCLASSIFIED DRUG;

ARTIFACT; CLINICAL PROTOCOL; CULTURE MEDIUM; EXOSOME; GENE CLUSTER; GENE EXPRESSION; GENE LIBRARY; GENE MAPPING; GENETIC ASSOCIATION; GENETIC CONSERVATION; GENETIC POLYMORPHISM; HUMAN; HUMAN VERSUS ANIMAL COMPARISON; MICROARRAY ANALYSIS; NONHUMAN; REVIEW; RNA ANALYSIS; ULTRACENTRIFUGATION;

EID: 85015617711     PISSN: None     EISSN: 20013078     Source Type: Journal    
DOI: 10.1080/20013078.2017.1272832     Document Type: Review

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