Low STAT3 expression sensitizes to toxic effects of β-adrenergic receptor stimulation in peripartum cardiomyopathy

European Heart Journal

Volumn 38, Issue 5, 2017, Pages 349-361

  Stapel, Britta ^a   Kohlhaas, Michael ^b   Ricke Hoch, Melanie ^a   Haghikia, Arash ^a   Erschow, Sergej ^a   Knuuti, Juhani ^c   Silvola, Johanna M U ^c   Roivainen, Anne ^c   Saraste, Antti ^c   Nickel, Alexander G ^b   Saar, Jasmin A ^b   Sieve, Irina ^a   Pietzsch, Stefan ^a   Müller, Mirco ^a   Bogeski, Ivan ^b   Kappl, Reinhard ^b   Jauhiainen, Matti ^d   Thackeray, James T ^a   Scherr, Michaela ^a   Bengel, Frank M ^a   Hagl, Christian ^e   Tudorache, Igor ^a   Bauersachs, Johann ^a   Maack, Christoph ^b   Hilfiker Kleiner, Denise ^a   more..

^a HANNOVER MEDICAL SCHOOL   (Germany)

^b SAARLAND UNIVERSITY   (Germany)

^c TURKU UNIVERSITY HOSPITAL   (Finland)

^d NATIONAL PUBLIC HEALTH INSTITUTE   (Finland)

^e UNIVERSITY OF MUNICH   (Germany)

Author keywords

Acute heart failure; Metabolism; Oxidative stress; Peripartum cardiomyopathy; STAT3; Adrenergic receptor stimulation

Indexed keywords

ACETIC ACID C 11; ANGIOTENSIN RECEPTOR ANTAGONIST; BETA 1 ADRENERGIC RECEPTOR; BROMOCRIPTINE; DIPEPTIDYL CARBOXYPEPTIDASE INHIBITOR; DOBUTAMINE; ETOMOXIR; FATTY ACID; GLUCOSE TRANSPORTER 4; INSULIN; LACTIC ACID; METOPROLOL; MICRORNA; MICRORNA 199A; MICRORNA 199A 5P; MICRORNA 7A; MICRORNA 7A 5P; NEU DIFFERENTIATION FACTOR; PERHEXILINE; PYRIDINE NUCLEOTIDE; PYRUVIC ACID; REACTIVE OXYGEN METABOLITE; STAT3 PROTEIN; TRIACYLGLYCEROL; UNCLASSIFIED DRUG; BETA 1 ADRENERGIC RECEPTOR STIMULATING AGENT; EPIDERMAL GROWTH FACTOR RECEPTOR 4; ERBB4 PROTEIN, MOUSE; ISOPRENALINE; MIRN199 MICRORNA, MOUSE; MIRN7 MICRORNA, MOUSE; PURINE NUCLEOTIDE; STAT3 PROTEIN, HUMAN;

ACUTE HEART FAILURE; ADULT; ADVERSE OUTCOME; AEROBIC METABOLISM; ANIMAL CELL; ANIMAL TISSUE; ARTICLE; BETA ADRENERGIC STIMULATION; CARDIAC MUSCLE CELL; CARDIOVASCULAR MORTALITY; CELL LOSS; CLINICAL ARTICLE; CONTROLLED STUDY; FEMALE; FOLLOW UP; GLUCOSE METABOLISM; GLUCOSE TRANSPORT; HEART LEFT VENTRICLE EJECTION FRACTION; HEART MUSCLE PERFUSION; HEART TRANSPLANTATION; HUMAN; LEFT VENTRICULAR ASSIST DEVICE; MALE; MOUSE; NONHUMAN; OXIDATIVE STRESS; PERIPARTUM CARDIOMYOPATHY; POSITRON EMISSION TOMOGRAPHY; PRIORITY JOURNAL; PROTEIN EXPRESSION; RESPIRATORY CHAIN; SIGNAL TRANSDUCTION; ANIMAL; ANTAGONISTS AND INHIBITORS; CARDIAC MUSCLE; CARDIOMYOPATHY; CHEMICALLY INDUCED; DEFICIENCY; GLUCOSE BLOOD LEVEL; HEART FAILURE; HEART LEFT VENTRICLE FUNCTION; HEART MITOCHONDRION; KNOCKOUT MOUSE; METABOLISM; PERINATAL PERIOD; PHYSIOLOGY; PUERPERAL DISORDER; RANDOMIZATION;

ADRENERGIC BETA-1 RECEPTOR AGONISTS; ADULT; ANIMALS; BLOOD GLUCOSE; CARDIOMYOPATHIES; DOBUTAMINE; FEMALE; HEART FAILURE; HUMANS; ISOPROTERENOL; MALE; MICE, KNOCKOUT; MICRORNAS; MITOCHONDRIA, HEART; MYOCARDIUM; MYOCYTES, CARDIAC; PERIPARTUM PERIOD; PUERPERAL DISORDERS; PURINE NUCLEOTIDES; RANDOM ALLOCATION; REACTIVE OXYGEN SPECIES; RECEPTOR, ERBB-4; STAT3 TRANSCRIPTION FACTOR; VENTRICULAR DYSFUNCTION, LEFT;

EID: 85015611636     PISSN: 0195668X     EISSN: 15229645     Source Type: Journal    
DOI: 10.1093/eurheartj/ehw086     Document Type: Article

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