Vitamin concentrations in human milk vary with time within feed, circadian rhythm, and single-dose supplementation

Journal of Nutrition

Volumn 147, Issue 4, 2017, Pages 603-611

  Hampel, Daniela ^a,b   Shahab Ferdows, Setareh ^a   Islam, M Munirul ^c   Peerson, Janet M ^a,b   Allen, Lindsay H ^a,b  

^a AGRICULTURAL RESEARCH SERVICE   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c INTERNATIONAL CENTRE FOR DIARRHOEAL DISEASE RESEARCH   (Bangladesh)

Author keywords

Acute supplementation effects; Circadian variation; Human milk; Lactation; Sample collection; Vitamins

Indexed keywords

ALPHA TOCOPHEROL; CYANOCOBALAMIN; FAT; NICOTINIC ACID; PYRIDOXINE; RETINOL; RIBOFLAVIN; THIAMINE; TRACE ELEMENT; VITAMIN;

ADULT; ARTICLE; BANGLADESH; BREAST MILK; CIRCADIAN RHYTHM; CONCENTRATION RESPONSE; DIETARY REFERENCE INTAKE; FEEDING BEHAVIOR; FEMALE; HUMAN; MILK LEVEL; VITAMIN SUPPLEMENTATION; CHEMISTRY; DIETARY SUPPLEMENT; MATERNAL NUTRITION; METABOLISM; PHYSIOLOGY; TIME FACTOR; YOUNG ADULT;

ADULT; CIRCADIAN RHYTHM; DIETARY SUPPLEMENTS; FEMALE; HUMANS; MATERNAL NUTRITIONAL PHYSIOLOGICAL PHENOMENA; MICRONUTRIENTS; MILK, HUMAN; TIME FACTORS; VITAMINS; YOUNG ADULT;

EID: 85015279618     PISSN: 00223166     EISSN: 15416100     Source Type: Journal    
DOI: 10.3945/jn.116.242941     Document Type: Article

References (37)

1. WHO. The optimal duration of exclusive breastfeeding: report of an Expert Consultation. Geneva (Switzerland): WHO; 2001
2. Allen LH. B-vitamins in breast milk: relative importance of maternal status and intake, and effects on infant status and function. Adv Nutr 2012;3:362-9
3. Hampel D, Allen LH. Analyzing B-vitamins in human milk: methodological approaches. Crit Rev Food Sci Nutr 2016;56:494-511
4. Institute of Medicine. Dietary Reference Intakes for thiamin, riboflavin, niacin, vitamin B6, folate, vitamin B12, pantothenic acid, biotin, and choline. Washington (DC): National Academies Press; 1998
5. Institute of Medicine. Dietary Reference Intakes for vitamin C, vitamin E, selenium, and carotenoids. Washington (DC): National Academies Press; 2000
6. Institute of Medicine. Dietary Reference Intakes for vitamin A, for vitamin K, arsenic, boron, chromium, copper, iodine, iron, manganese, molybdenum, nickel, silicon, vanadium, and zinc. Washington (DC): National Academies Press; 2001
7. Institute of Medicine. Dietary Reference Intakes for calcium and vitamin D. Washington (DC): National Academies Press; 2010
8. Tamura T, Picciano MF. Folate determination in human milk. J Nutr Sci Vitaminol (Tokyo) 2006;52:161
9. Shane B, Tamura T, Stokstad EL. Folate assay: a comparison of radioassay and microbiological methods. Clin Chim Acta 1980;100:13-9
10. Roughead ZK, McCormick DB. Flavin composition of human milk. Am J Clin Nutr 1990;52:854-7
11. Hampel D, Shahab-Ferdows S, Adair LS, Bentley ME, Falx VL, Jamieson DJ, Ellington SR, Tegha G, Chasela CS, Kamwendo D, et al. Thiamin and riboflavin in human milk: effects of lipid-based nutrient supplementation and stage of lactation on vitamer secretion and contributions to total vitamin content. PLoS One 2016;11:e0149479
12. Hampel D, Shahab-Ferdows S, Domek JM, Siddiqua T, Raqib R, Allen LH. Competitive chemiluminescent enzyme immunoassay for vitamin B12 analysis in human milk. Food Chem 2014;153:60-5
13. Hampel D, York ER, Allen LH. Ultra-performance liquid chromatography tandem mass-spectrometry (UPLC-MS/MS) for the rapid, simultaneous analysis of thiamin, riboflavin, flavin adenine dinucleotide, nicotinamide and pyridoxal in human milk. J Chromatogr B Analyt Technol Biomed Life Sci 2012;903:7-13
14. Duggan C, Srinivasan K, Thomas T, Samuel T, Rajendran R, Muthayya S, Finkelstein JL, Lukose A, Fawzi W, Allen LH, et al. Vitamin B-12 supplementation during pregnancy and early lactation increases maternal, breast milk, and infant measures of vitamin B-12 status. J Nutr 2014;144:758-64
15. Allen LH, Hampel D, Shahab-Ferdows S, York ER, Adair LS, Flax VL, Tegha G, Chasela CS, Kamwendo D, Jamieson DJ, et al. Antiretroviral therapy provided to HIV-infected Malawian women in a randomized trial diminishes the positive effects of lipid-based nutrient supplements on breast-milk B vitamins. Am J Clin Nutr 2015;102:1468-74
16. Bae S, West AA, Yan J, Jiang X, Perry CA, Malysheva O, Stabler SP, Allen RH, Caudill MA. Vitamin B-12 status differs among pregnant, lactating, and control women with equivalent nutrient intakes. J Nutr 2015;145:1507-14
17. Shahab-Ferdows S, Engle-Stone R, Hampel D, Ndjebayi AO, Nankap M, Brown KH, Allen LH. Regional, socioeconomic, and dietary risk factors for vitamin B-12 deficiency differ from those for folate deficiency in Cameroonian women and children. J Nutr 2015;145:2587-95
18. Ren X, Yang Z, Shao B, Yin S-a, Yang X. B-vitamin levels in human milk among different lactation stages and areas in china. PLoS One 2015;10:e0133285
19. Siddiqua TJ, Ahmad SM, Ahsan KB, Rashied M, Roy A, Rahman SM, Shahab-Ferdows S, Hampel D, Ahmed T, Allen LH, et al. Vitamin B12 supplementation during pregnancy and postpartum improves B12 status of both mothers and infants but vaccine response in mothers only: a randomized clinical trial in Bangladesh. Eur J Nutr 2016;55:281-93
20. Williams AM, Chantry CJ, Young SL, Achando BS, Allen LH, Arnold BF, Colford JM, Dentz HN, Hampel D, Kiprotich MC, et al. Vitamin B-12 concentrations in breast milk are low and are not associated with reported household hunger, recent animal-source food, or vitamin B-12 intake in women in rural Kenya. J Nutr 2016;146:1125-31
21. Whitfield KC, Karakochuk CD, Kroeun H, Hampel D, Sokhoing L, Chan BC, Borath M, Sophonneary P, McLean J, Talukder A, et al. Perinatal consumption of thiamin-fortified fish sauce in rural Cambodia: a randomized controlled efficacy trial. JAMA Pediatr 2016; 170: e162065
22. Nail PA, Thomas M, Eakin R. The effect of thiamin and riboflavin supplementation on the level of those vitamins in human breast milk and urine. Am J Clin Nutr 1980;33:198-204
23. Dancheck B, Nussenblatt V, Ricks MO, Kumwenda N, Neville MC, Moncrief DT, Taha TE, Semba RD. Breast milk retinol concentrations are not associated with systemic inflammation among breast-feeding women in Malawi. J Nutr 2005;135:223-6
24. Andersen SL, Møller M, Laurberg P. Iodine concentrations in milk and in urine during breastfeeding are differently affected by maternal fluid intake. Thyroid 2014;24:764-72
25. Smilowitz JT, OSullivan A, Barile D, German JB, Lönnerdal B, Slupsky CM. The human milk metabolome reveals diverse oligosaccharide profiles. J Nutr 2013;143:1709-18
26. Antonakou A, Chiou A, Andrikopoulos NK, Bakoula C, Matalas A-L. Breast milk tocopherol content during the first six months in exclusively breastfeeding Greek women. Eur J Nutr 2011;50:195-202
27. Davenport C, Yan J, Taesuwan S, Shields K, West AA, Jiang X, Peery CA, Malysheva OV, Stabler SP, Allen RH, et al. Choline intakes exceeding recommendations during human lactation improve breastmilk choline content by increasing PEMT pathway metabolites. J Nutr Biochem 2015;26:903-11
28. Ozarda Y, Cansev M, Ulus IH. Breast milk choline contents are associated with inflammatory status of breastfeeding women. J Hum Lact 2014;30:161-6
29. Greibe E, Lildballe DL, Streym S, Vestergaard P, Rejnmark L, Mosekilde L, Nexo E. Cobalamin and haptocorrin in human milk and cobalamin-related variables in mother and child: a 9-mo longitudinal study. Am J Clin Nutr 2013;98:389-95
30. Picciano MF, Guthrie HA. Copper, iron, and zinc contents of mature human milk. Am J Clin Nutr 1976;29:242-54
31. Ortega RM, Martínez RM, Andrés P, Marín-Arias L, L ópez-Sobaler AM. Thiamin status during the third trimester of pregnancy and its influence on thiamin concentrations in transition and mature breast milk. Br J Nutr 2004;92:129-35
32. Ooylan LM, Hart S, Porter KB, Driskell JA. Vitamin B-6 content of breast milk and neonatal behavioral functioning. J Am Diet Assoc 2002;102:1433-8
33. Turner T, Burri BJ. Rapid isocratic HPLC method and sample extraction procedures for measuring carotenoid, retinoid, and tocopherol concentrations in human blood and breast milk for intervention studies. Chromatographia 2012;75:241-52
34. Trugo NMF, Sardinha F. Cobalamin and cobalamin-binding capacity in human milk. Nutr Res 1994;14:23-33
35. Montalbetti N, Dalghi MG, Albrecht C, Hediger MA. Nutrient transport in the mammary gland: calcium, trace minerals and water soluble vitamins. J Mammary Gland Biol Neoplasia 2014;19:73-90
36. Debier C, Pottier J, Goffe Ch, Larondelle Y. Present knowledge and unexpected behaviours of vitamins A and E in colostrum and milk. Livest Prod Sci 2005;98:135-47
37. Schweigert FJ, Bathe K, Chen F, Büscher U, Dudenhausen JW. Effect of the stage of lactation in human on carotenoid levels in milk, blood plasma and plasma lipoprotein fractions. Eur J Nutr 2004;43:39-44