Heparin-induced amyloid fibrillation of β2-microglobulin explained by solubility and a supersaturation-dependent conformational phase diagram

Protein Science

Volumn 26, Issue 5, 2017, Pages 1024-1036

  So, Masatomo ^a   Hata, Yasuko ^a   Naiki, Hironobu ^b   Goto, Yuji ^a  

^a OSAKA UNIVERSITY   (Japan)

^b UNIVERSITY OF FUKUI   (Japan)

Author keywords

amyloid fibrillation; heparin; protein aggregation; salt effects; solubility; supersaturation; 2 microglobulin

Indexed keywords

AMYLOID PROTEIN; BETA 2 MICROGLOBULIN; HEPARIN; SODIUM CHLORIDE; SULFATE; AMYLOID;

AMYLOIDOSIS; ARTICLE; CIRCULAR DICHROISM; CONFORMATIONAL TRANSITION; HEPARIN INDUCED AMYLOID FIBRILLATION; HUMAN; LIGHT SCATTERING; PRIORITY JOURNAL; PROTEIN AGGREGATION; SOLUBILITY; TRANSMISSION ELECTRON MICROSCOPY; ADVERSE EFFECTS; CHEMICAL MODEL; CHEMISTRY; HEMODIALYSIS; METABOLISM; PH; PROTEIN QUATERNARY STRUCTURE;

AMYLOID; AMYLOIDOSIS; BETA 2-MICROGLOBULIN; HEPARIN; HYDROGEN-ION CONCENTRATION; MODELS, CHEMICAL; PROTEIN STRUCTURE, QUATERNARY; RENAL DIALYSIS;

EID: 85015217745     PISSN: 09618368     EISSN: 1469896X     Source Type: Journal    
DOI: 10.1002/pro.3149     Document Type: Article

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