Iron, Copper, and Zinc Concentration in Aβ Plaques in the APP/PS1 Mouse Model of Alzheimer’s Disease Correlates with Metal Levels in the Surrounding Neuropil

ACS Chemical Neuroscience

Volumn 8, Issue 3, 2017, Pages 629-637

  James, Simon A ^a,b   Churches, Quentin I ^c   De Jonge, Martin D ^b   Birchall, Ian E ^a   Streltsov, Victor ^c   McColl, Gawain ^a   Adlard, Paul A ^a   Hare, Dominic J ^a,d  

^a UNIVERSITY OF MELBOURNE   (Australia)

^b AUSTRALIAN SYNCHROTRON   (Australia)

^c CSIRO   (Australia)

^d UNIVERSITY OF TECHNOLOGY SYDNEY   (Australia)

Author keywords

A plaques; copper; iron; XFM mapping; zinc

Indexed keywords

AMYLOID BETA PROTEIN; AMYLOID PRECURSOR PROTEIN; COPPER; IRON; PRESENILIN 1; ZINC; METAL; PSEN1 PROTEIN, HUMAN;

ALZHEIMER DISEASE; AMYLOID PLAQUE; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRAIN REGION; CONTROLLED STUDY; FLUORESCENCE MICROSCOPY; HIPPOCAMPUS; IMMUNOHISTOCHEMISTRY; METAL BINDING; MOUSE; NEUROPIL; NONHUMAN; PRIORITY JOURNAL; RADIATION SCATTERING; X RAY FLUORESCENCE; ANIMAL; BRAIN; CHEMISTRY; DISEASE MODEL; GENETICS; HUMAN; METABOLISM; MUTATION; PATHOLOGY; TRANSGENIC MOUSE; X RAY;

ALZHEIMER DISEASE; AMYLOID BETA-PEPTIDES; AMYLOID BETA-PROTEIN PRECURSOR; ANIMALS; BRAIN; COPPER; DISEASE MODELS, ANIMAL; HUMANS; IRON; METALS; MICE; MICE, TRANSGENIC; MUTATION; NEUROPIL; PLAQUE, AMYLOID; PRESENILIN-1; X-RAYS; ZINC;

EID: 85015191628     PISSN: None     EISSN: 19487193     Source Type: Journal    
DOI: 10.1021/acschemneuro.6b00362     Document Type: Article

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