Adipose-derived stem cells: Therapy through paracrine actions

Stem Cells and Cancer Stem Cells, Volume 4: Therapeutic Applications in Disease and Injury

Volumn , Issue , 2012, Pages 203-216

  Lin, Ching Shwun ^a   Lue, Tom F ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Adipose derived stem cells; Mesenchymal stem cell therapy; Paracrine

Indexed keywords

EID: 85014848746     PISSN: None     EISSN: None     Source Type: Book    
DOI: 10.1007/978-94-007-2828-8_18     Document Type: Chapter

References (50)

1. Albersen M, Fandel TM, Lin G, Wang G, Banie L, Lin CS, Lue TF (2010) Injections of adipose tissue-derived stem cells and stem cell lysate improve recovery of erectile function in a rat model of cavernous nerve injury. J Sex Med 7: 3331-3340
2. Alt E, Pinkernell K, Scharlau M, Coleman M, Fotuhi P, Nabzdyk C, Matthias N, Gehmert S, Song YH (2010) Effect of freshly isolated autologous tissue resident stromal cells on cardiac function and perfusion following acute myocardial infarction. Int J Cardiol 144: 26-35
3. Bi B, Schmitt R, Israilova M, Nishio H, Cantley LG (2007) Stromal cells protect against acute tubular injury via an endocrine effect. J Am Soc Nephrol 18: 2486-2496
4. Cai L, Johnstone BH, Cook TG, Tan J, Fishbein MC, Chen PS, March KL (2009) IFATS collection: human adipose tissue-derived stem cells induce angiogenesis and nerve sprouting following myocardial infarction, in conjunction with potent preservation of cardiac function. Stem Cells 27: 230-237
5. Chen YT, Sun CK, Lin YC, Chang LT, Chen YL, Tsai TH, Chung SY, Chua S, Kao YH, Yen CH, Shao PL, Chang KC, Leu S, Yip HK (2011) Adipose-derived mesenchymal stem cell protects kidneys against ischemiareperfusion injury through suppressing oxidative stress and inflammatory reaction. J Transl Med 9: 51
6. da Silva Meirelles L, Sand TT, Harman RJ, Lennon DP, Caplan AI (2009) Msc frequency correlates with blood vessel density in equine adipose tissue. Tissue Eng Part A 15: 221-229
7. Danoviz ME, Nakamuta JS, Marques FL, dos Santos L, Alvarenga EC, dos Santos AA, Antonio EL, Schettert IT, Tucci PJ, Krieger JE (2010) Rat adipose tissuederived stem cells transplantation attenuates cardiac dysfunction post infarction and biopolymers enhance cell retention. PLoS One 5: e12077
8. Fandel TM, Albersen M, Lin G, Qiu X, Ning H, Banie L, Lue TF, Lin CS (2012) Recruitment of intracavernously injected adipose-derived stem cells to the major pelvic ganglia improves erectile function in a rat model of cavernous nerve injury. Eu Urol 61: 201-210
9. Fatar M, Stroick M, Griebe M, Marwedel I, Kern S, Bieback K, Giesel FL, Zechmann C, Kreisel S, Vollmar F, Alonso A, Back W, Meairs S, Hennerici MG (2008) Lipoaspiratederived adult mesenchymal stem cells improve functional outcome during intracerebral hemorrhage by proliferation of endogenous progenitor cells stem cells in intracerebral hemorrhages. Neurosci Lett 443: 174-178
10. Feng Z, Ting J, Alfonso Z, Strem BM, Fraser JK, Rutenberg J, Kuo HC, Pinkernell K (2010) Fresh and cryopreserved, uncultured adipose tissue-derived stem and regenerative cells ameliorate ischemia-reperfusioninduced acute kidney injury. Nephrol Dial Transplant 25: 3874-3884
11. Gangenahalli GU, Singh VK, Verma YK, Gupta P, Sharma RK, Chandra R, Luthra PM (2006) Hematopoietic stem cell antigen cd34: role in adhesion or homing. Stem Cells Dev 15: 305-313
12. Garcia MM, Fandel TM, Lin G, Shindel AW, Banie L, Lin CS, Lue TF (2010) Treatment of erectile dysfunction in the obese type 2 diabetic zdf rat with adipose tissuederived stem cells. J Sex Med 7: 89-98
13. Ghannam S, Bouffi C, Djouad F, Jorgensen C, Noel D (2010) Immunosuppression by mesenchymal stem cells: mechanisms and clinical applications. Stem Cell Res Ther 1: 2
14. Housman TS, Lawrence N, Mellen BG, George MN, Filippo JS, Cerveny KA, DeMarco M, Feldman SR, Fleischer AB (2002) The safety of liposuction: results of a national survey. Dermatol Surg 28: 971-978
15. Huang YC, Ning H, Shindel AW, Fandel TM, Lin G, Harraz AM, Lue TF, Lin CS (2010a) The effect of intracavernous injection of adipose tissue-derived stem cells on hyperlipidemia-associated erectile dysfunction in a rat model. J Sex Med 7: 1391-1400
16. Huang YC, Shindel AW, Ning H, Lin G, Harraz AM, Wang G, Garcia M, Lue TF, Lin CS (2010b) Adipose derived stem cells ameliorate hyperlipidemia associated detrusor overactivity in a rat model. J Urol 183: 1232-1240
17. Hwangbo S, Kim J, Her S, Cho H, Lee J (2010) Therapeutic potential of human adipose stem cells in a rat myocardial infarction model. Yonsei Med J 51: 69-76
18. Ichim TE, Harman RJ, Min WP, Minev B, Solano F, Rodriguez JP, Alexandrescu DT, De Necochea-Campion R, Hu X, Marleau AM, Riordan NH (2010) Autologous stromal vascular fraction cells: a tool for facilitating tolerance in rheumatic disease. Cell Immunol 264: 7-17
19. Ii M, Horii M, Yokoyama A, Shoji T, Mifune Y, Kawamoto A, Asahi M, Asahara T (2011) Synergistic effect of adipose-derived stem cell therapy and bone marrow progenitor recruitment in ischemic heart. Lab Invest 91: 539-552
20. Ikegame Y, Yamashita K, Hayashi SI, Mizuno H, Tawada M, You F, Yamada K, Tanaka Y, Egashira Y, Nakashima S, Yoshimura SI, Iwama T (2011) Comparison of mesenchymal stem cells from adipose tissue and bone marrow for ischemic stroke therapy. Cytotherapy 13: 675-685
21. Kang SK, Lee DH, Bae YC, Kim HK, Baik SY, Jung JS (2003) Improvement of neurological deficits by intracerebral transplantation of human adipose tissuederived stromal cells after cerebral ischemia in rats. Exp Neurol 183: 355-366
22. Kim JM, Lee ST, Chu K, Jung KH, Song EC, Kim SJ, Sinn DI, Kim JH, Park DK, Kang KM, Hyung HN, Park HK, Won CH, Kim KH, Kim M, Kun LS, Roh JK (2007) Systemic transplantation of human adipose stem cells attenuated cerebral inflammation and degeneration in a hemorrhagic stroke model. Brain Res 1183: 43-50
23. Kim U, Shin DG, Park JS, Kim YJ, Park SI, Moon YM, Jeong KS (2011) Homing of adipose-derived stem cells to radiofrequency catheter ablated canine atrium and differentiation into cardiomyocyte-like cells. Int J Cardiol 146: 371-378
24. Leu S, Lin YC, Yuen CM, Yen CH, Kao YH, Sun CK, Yip HK (2010) Adipose-derived mesenchymal stem cells markedly attenuate brain infarct size and improve neurological function in rats. J Transl Med 8: 63
25. Li N, Yang H, Lu L, Duan C, Zhao C, Zhao H (2008) Comparison of the labeling efficiency of brdu, dii and fish labeling techniques in bone marrow stromal cells. Brain Res 1215: 11-19
26. Li K, Han Q, Yan X, Liao L, Zhao RC (2010) Not a process of simple vicariousness, the differentiation of human adipose-derived mesenchymal stem cells to renal tubular epithelial cells plays an important role in acute kidney injury repairing. Stem Cells Dev 19: 1267-1275
27. Lin G, Garcia M, Ning H, Banie L, Guo YL, Lue TF, Lin CS (2008) Defining stem and progenitor cells within adipose tissue. Stem Cells Dev 17: 1053-1063
28. Lin G, Wang G, Banie L, Ning H, Shindel AW, Fandel TM, Lue TF, Lin CS (2010a) Treatment of stress urinary incontinence with adipose tissue-derived stem cells. Cytotherapy 12: 88-95
29. Lin CS, Xin ZC, Deng CH, Ning H, Lin G, Lue TF (2010b) Defining adipose tissue-derived stem cells in tissue and in culture. Histol Histopathol 25: 807-815
30. Lin G, Liu G, Banie L, Wang G, Ning H, Lue TF, Lin CS (2011a) Tissue distribution of mesenchymal stem cell marker stro-1. Stem Cells Dev 20: 1747-1752
31. Lin G, Qiu X, Fandel T, Banie L, Wang G, Lue TF, Lin CS (2011b) Tracking intracavernously injected adiposederived stem cells to bone marrow. Int J Impot Res 23: 268-275
32. Mazo M, Planat-Benard V, Abizanda G, Pelacho B, Leobon B, Gavira JJ, Penuelas I, Cemborain A, Penicaud L, Laharrague P, Joffre C, Boisson M, Ecay M, Collantes M, Barba J, Casteilla L, Prosper F (2008) Transplantation of adipose derived stromal cells is associated with functional improvement in a rat model of chronic myocardial infarction. Eur J Heart Fail 10: 454-462
33. Mazo M, Gavira JJ, Pelacho B, Prosper F (2011) Adiposederived stem cells for myocardial infarction. J Cardiovasc Transl Res 4: 145-153
34. Ning H, Liu G, Lin G, Yang R, Lue TF, Lin CS (2009) Fibroblast growth factor 2 promotes endothelial differentiation of adipose tissue-derived stem cells. J Sex Med 6: 967-979
35. Okura H, Matsuyama A, Lee CM, Saga A, Kakuta-Yamamoto A, Nagao A, Sougawa N, Sekiya N, Takekita K, Shudo Y, Miyagawa S, Komoda H, Okano T, Sawa Y (2010) Cardiomyoblast-like cells differentiated from human adipose tissue-derived mesenchymal stem cells improve left ventricular dysfunction and survival in a rat myocardial infarction model. Tissue Eng Part C Methods 16: 417-425
36. Qiu X, Fandel TM, Lin G, Huang YC, Dai YT, Lue TF, Lin CS (2011) Cavernous smooth muscle hyperplasia in a rat model of hyperlipidemia-associated erectile dysfunction. BJU Int 108: 1866-1872
37. Rigol M, Solanes N, Farre J, Roura S, Roque M, Berruezo A, Bellera N, Novensa L, Tamborero D, Prat-Vidal C, Huzman MA, Batlle M, Hoefsloot M, Sitges M, Ramirez J, Dantas AP, Merino A, Sanz G, Brugada J, Bayes-Genis A, Heras M (2010) Effects of adipose tissue-derived stem cell therapy after myocardial infarction: impact of the route of administration. J Card Fail 16: 357-366
38. Sadat S, Gehmert S, Song YH, Yen Y, Bai X, Gaiser S, Klein H, Alt E (2007) The cardioprotective effect of mesenchymal stem cells is mediated by igf-i and vegf. Biochem Biophys Res Commun 363: 674-679
39. Schenke-Layland K, Strem BM, Jordan MC, Deemedio MT, Hedrick MH, Roos KP, Fraser JK, Maclellan WR (2009) Adipose tissue-derived cells improve cardiac function following myocardial infarction. J Surg Res 153: 217-223
40. Simmons PJ, Torok-Storb B (1991a) Cd34 expression by stromal precursors in normal human adult bone marrow. Blood 78: 2848-2853
41. Simmons PJ, Torok-Storb B (1991b) Identification of stromal cell precursors in human bone marrow by a novel monoclonal antibody, stro-1. Blood 78: 55-62
42. Strem BM, Hicok KC, Zhu M, Wulur I, Alfonso Z, Schreiber RE, Fraser JK, Hedrick MH (2005a) Multipotential differentiation of adipose tissue-derived stem cells. Keio J Med 54: 132-141
43. Strem BM, Zhu M, Alfonso Z, Daniels EJ, Schreiber R, Beygui R, MacLellan WR, Hedrick MH, Fraser JK (2005b) Expression of cardiomyocytic markers on adipose tissue-derived cells in a murine model of acute myocardial injury. Cytotherapy 7: 282-291
44. Suga H, Matsumoto D, Eto H, Inoue K, Aoi N, Kato H, Araki J, Yoshimura K (2009) Functional implications of cd34 expression in human adipose-derived stem/progenitor cells. Stem Cells Dev 18: 1201-1210
45. Valina C, Pinkernell K, Song YH, Bai X, Sadat S, Campeau RJ, Le Jemtel TH, Alt E (2007) Intracoronary administration of autologous adipose tissue-derived stem cells improves left ventricular function, perfusion, and remodelling after acute myocardial infarction. Eur Heart J 28: 2667-2677
46. Wang L, Deng J, Tian W, Xiang B, Yang T, Li G, Wang J, Gruwel M, Kashour T, Rendell J, Glogowski M, Tomanek B, Freed D, Deslauriers R, Arora RC, Tian G (2009) Adipose-derived stem cells are an effective cell candidate for treatment of heart failure: an MR imaging study of rat hearts. Am J Physiol Heart Circ Physiol 297: H1020-H1031
47. Yamamoto T, Gotoh M, Hattori R, Toriyama K, Kamei Y, Iwaguro H, Matsukawa Y, Funahashi Y (2010) Periurethral injection of autologous adipose-derived stem cells for the treatment of stress urinary incontinence in patients undergoing radical prostatectomy: report of two initial cases. Int J Urol 17: 75-82
48. Zhang H, Ning H, Banie L, Wang G, Lin G, Lue TF, Lin CS (2010) Adipose tissue-derived stem cells secrete cxcl5 cytokine with chemoattractant and angiogenic properties. Biochem Biophys Res Commun 402: 560-564
49. Zhang H, Yang R, Wang Z, Lin G, Lue TF, Lin CS (2011) Adipose tissue-derived stem cells secrete cxcl5 cytokine with neurotrophic effects on cavernous nerve regeneration. J Sex Med 8: 437-446
50. Zuk PA, Zhu M, Mizuno H, Huang J, Futrell JW, Katz AJ, Benhaim P, Lorenz HP, Hedrick MH (2001) Multilineage cells from human adipose tissue: implications for cell-based therapies. Tissue Eng 7: 211-228