Fresh and cryopreserved, uncultured adipose tissue-derived stem and regenerative cells ameliorate ischemia-reperfusion-induced acute kidney injury

Nephrology Dialysis Transplantation

Volumn 25, Issue 12, 2010, Pages 3874-3884

  Feng, Zheng ^a   Ting, Joey ^a   Alfonso, Zeni ^a   Strem, Brian M ^a   Fraser, John K ^a   Rutenberg, Joshua ^a   Kuo, Hai Chien ^a   Pinkernell, Kai ^a  

^a Cytori Therapeutics Inc   (United States)

Author keywords

acute renal failure; adipose tissue derived stem and regenerative cells; adult stem cells; cell therapy; ischemia reperfusion injury

Indexed keywords

CREATININE; CXCL2 CHEMOKINE; INTERLEUKIN 6;

ADIPOSE TISSUE; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL THERAPY; CONTROLLED STUDY; CREATININE BLOOD LEVEL; CRYOPRESERVATION; KIDNEY FUNCTION; KIDNEY INJURY; KIDNEY ISCHEMIA; KIDNEY TUBULE NECROSIS; MORTALITY; NONHUMAN; PRIORITY JOURNAL; RAT; RENAL PROTECTION; REPERFUSION INJURY; STEM CELL;

ACUTE KIDNEY INJURY; ADIPOSE TISSUE; ANIMALS; CELL MOVEMENT; CELL PROLIFERATION; CHEMOKINE CXCL2; CRYOPRESERVATION; INTERLEUKIN-6; KIDNEY TUBULES; MACROPHAGES; MESENCHYMAL STEM CELL TRANSPLANTATION; MODELS, ANIMAL; NECROSIS; RATS; REPERFUSION INJURY; STEM CELLS; TISSUE THERAPY;

EID: 78649505867     PISSN: 09310509     EISSN: 14602385     Source Type: Journal    
DOI: 10.1093/ndt/gfq603     Document Type: Article

References (51)

1. Kidney Disease: A Growing Public Health and Economic Concern http://www.asn-online.org/facts-and-statistics/kd-health-threat.pdf (9 June 2009, date last accessed)
2. Devarajan P. Update on mechanisms of ischemic acute kidney injury. J Am Soc Nephrol 2006; 17: 1503-1520
3. Endre ZH. Acute kidney injury: definitions and new paradigms. Adv Chronic Kidney Dis 2008; 15: 213-221
4. Hoste EA, Schurgers M. Epidemiology of acute kidney injury: how big is the problem? Crit Care Med 2008; 36: S146-S151
5. Kellum JA, Hoste EA. Acute kidney injury: epidemiology and assessment. Scand J Clin Lab Invest Suppl 2008; 241: 6-11
6. Hoste EA, Cruz DN, Davenport A et al. The epidemiology of cardiac surgery-associated acute kidney injury. Int J Artif Organs 2008; 31: 158-165 (Pubitemid 351425013)
7. Langenberg C, Bagshaw SM, May CN et al. The histopathology of septic acute kidney injury: a systematic review. Crit Care 2008; 12: R38
8. Lin J, Bonventre JV Prevention of radiocontrast nephropathy. Curr Opin Nephrol Hypertens 2005; 14: 105-110
9. Schetz M, Bove T, Morelli A et al. Prevention of cardiac surgery-associated acute kidney injury. Int J Artif Organs 2008; 31: 179-189
10. Chatterjee PK, Thiemermann C. Emerging drugs for renal failure. Expert Opin Emerg Drugs 2003; 8: 389-435
11. Chatterjee PK. Novel pharmacological approaches to the treatment of renal ischemia-reperfusion injury: a comprehensive review. Naunyn Schmiedebergs Arch Pharmacol 2007; 376: 1-43
12. Cantley LG. Adult stem cells in the repair of the injured renal tubule. Nat Clin Pract Nephrol 2005; 1: 22-32
13. Fraser JK, Schreiber RE, Zuk PA et al. Adult stem cell therapy for the heart. Int J Biochem Cell Biol 2004; 36: 658-666
14. Strem BM, Hedrick MH. The growing importance of fat in regenerative medicine. Trends Biotechnol 2005; 23: 64-66
15. Alt E, Pinkernell K, Scharlau M et al. Effect of freshly isolated autologous tissue resident stromal cells on cardiac function and perfusion following acute myocardial infarction. Int J Cardiol 2009 May 13. [Epub ahead of print]
16. Schenke-Layland K, Strem BM, Jordan MC et al. Adipose tissue-derived cells improve cardiac function following myocardial infarction. J Surg Res 2008; 153: 217-223
17. Lin K, Matsubara Y, Masuda Y et al. Characterization of adipose tissue-derived cells isolated with the Celution system. Cytotherapy 2008; 10: 417-426
18. Bi B, Schmitt R, Israilova M et al. Stromal cells protect against acute tubular injury via an endocrine effect. J Am Soc Nephrol 2007; 18: 2486-2496
19. Togel F, Hu Z, Weiss K et al. Administered mesenchymal stem cells protect against ischemic acute renal failure through differentiation-independent mechanisms. Am J Physiol Renal Physiol 2005; 289: F31-F42 (Pubitemid 40863570)
20. Fiorina P, Ansari MJ, Jurewicz M et al. Role of CXC chemokine receptor 3 pathway in renal ischemic injury. J Am Soc Nephrol 2006; 17: 716-723
21. Coombes JD, Mreich E, Liddle C et al. Rapamycin worsens renal function and intratubular cast formation in protein overload nephropathy. Kidney Int 2005; 68: 2599-2607
22. Beillard E, Pallisgaard N, Van der Velden Vet al. Evaluation of candidate control genes for diagnosis and residual disease detection in leukemic patients using 'real-time' quantitative reverse-transcriptase polymerase chain reaction (RQ-PCR)-a Europe Against Cancer Program. Leukemia 2003; 17: 2474-2486
23. Strem BM, Hicok KC, Zhu M et al. Multipotential differentiation of adipose tissue-derived stem cells. Keio J Med 2005; 54: 132-141
24. Duffield JS, Bonventre JV Kidney tubular epithelium is restored without replacement with bone marrow-derived cells during repair after ischemic injury. Kidney Int 2005; 68: 1956-1961
25. Morigi M, Introna M, Imberti B et al. Human bone marrow mesenchymal stem cells accelerate recovery of acute renal injury and prolong survival in mice. Stem Cells 2008; 26: 2075-2082
26. Tögel F, Cohen A, Zhang P et al. Autologous and allogeneic marrow stromal cells are safe and effective for the treatment of acute kidney injury. Stem Cells Dev 2009; 18: 475-485
27. Vulliet PR, Greeley M, Halloran SM et al. Intra-coronary arterial injection of mesenchymal stromal cells and microinfarction in dogs. Lancet 2004; 363: 783-784
28. Moelker AD, Baks T, Wever KM et al. Intracoronary delivery of umbilical cord blood derived unrestricted somatic stem cells is not suitable to improve LV function after myocardial infarction in swine. J Mol Cell Cardiol 2007; 42: 735-745
29. Meliga E, Duckers HJ, Van Geuns RJ et al. Adipose derived stem cells: new kids on the block. EuroIntervention 2007; 2: B26-B32
30. Mukherjee D, Cho L. Renal and mesenteric artery intervention. Guide to Peripheral and Cerebrovascular Intervention. London, UK: Remedica Medical Education and Publishing, 2004, 108-116
31. Kinsey GR, Li L, Okusa MD. Inflammation in acute kidney injury. Nephron Exp Nephrol 2008; 109: e102-e107
32. Thurman JM. Triggers of inflammation after renal ischemia/reperfu-sion. Clin Immunol 2007; 123: 7-13
33. Furuichi K, Wada T, Iwata Yet al. Interleukin-1-dependent sequential chemokine expression and inflammatory cell infiltration in ischemia-reperfusion injury. Crit Care Med 2006; 34: 2447-2455
34. Furuichi K, Wada T, Kaneko S et al. Roles of chemokines in renal ischemia/reperfusion injury. Front Biosci 2008; 13: 4021-4028
35. Li L, Huang L, Sung SS et al. NKT cell activation mediates neutrophil IFN-gamma production and renal ischemia-reperfusion injury. J Immunol 2007; 178: 5899-5911
36. Shigeoka AA, Holscher TD, King AJ et al. TLR2 is constitutively expressed within the kidney and participates in ischemic renal injury through both MyD88-dependent and -independent pathways. J Immunol 2007; 178: 6252-6258
37. Ko GJ, Boo CS, Jo SK et al. Macrophages contribute to the development of renal fibrosis following ischaemia/reperfusion-induced acute kidney injury. Nephrol Dial Transplant 2008; 23: 842-852
38. Simmons EM, Himmelfarb J, Sezer MT et al. Plasma cytokine levels predict mortality in patients with acute renal failure. Kidney Int 2004; 65: 1357-1365 (Pubitemid 38406974)
39. Jo SK, Sung SA, Cho WY et al. Macrophages contribute to the initiation of ischaemic acute renal failure in rats. Nephrol Dial Transplant 2006; 21: 1231-1239
40. Cui L, Yin S, Liu W et al. Expanded adipose-derived stem cells suppress mixed lymphocyte reaction by secretion of prostaglandin E2. Tissue Eng 2007; 13: 1185-1195
41. Fang B, Song Y, Liao L et al. Favorable response to human adipose tissue-derived mesenchymal stem cells in steroid-refractory acute graft-versus-host disease. Transplant Proc 2007; 39: 3358-3362 (Pubitemid 350251475)
42. Fang B, Song YP, Liao LM et al. Treatment of severe therapy-resistant acute graft-versus-host disease with human adipose tissue-derived mesenchymal stem cells. Bone Marrow Transplant 2006; 38: 389-390
43. Rehman J, Traktuev D, Li J et al. Secretion of angiogenic and anti-apoptotic factors by human adipose stromal cells. Circulation 2004; 109: 1292-1298
44. Zhu M, Zhou Z, Chen Y et al. Supplementation of fat grafts with adipose-derived regenerative cells (ADRCs) improves long-term graft retention. Ann Plast Surg 2010; 64: 222-228
45. Lin F, Moran A, Igarashi P. Intrarenal cells, not bone marrow-derived cells, are the major source for regeneration in postischemic kidney. J Clin Invest 2005; 115: 1756-1764
46. Chen J, Park HC, Addabbo F et al. Kidney-derived mesenchymal stem cells contribute to vasculogenesis, angiogenesis and endothelial repair. Kidney Int 2008; 74: 879-889
47. Sagrinati C, Ronconi E, Lazzeri E et al. Stem-cell approaches for kidney repair: choosing the right cells. Trends Mol Med 2008; 14: 277-285
48. Baxter MA, Wynn RF, Jowitt SN et al. Study of telomere length reveals rapid aging of human marrow stromal cells following in vitro expansion. Stem Cells 2004; 22: 675-682
49. Walter DH, Dimmeler S. Endothelial progenitor cells: regulation and contribution to adult neovascularization. Herz 2002; 27: 579-588
50. Fraser JK, Wulur I, Alfonso Z et al. Differences in stem and progenitor cell yield in different subcutaneous adipose tissue depots. Cytotherapy 2007; 9: 459-467
51. Zhu M, Kohan E, Bradley J et al. The effect of age on osteogenic, adipogenic and proliferative potential of female adipose-derived stem cells. J Tissue Eng Regen Med 2009; 3: 290-301