Bug mapping and fitness testing of chemically synthesized chromosome X

Science

Volumn 355, Issue 6329, 2017, Pages

  Wu, Yi ^a   Li, Bing Zhi ^a   Zhao, Meng ^a   Mitchell, Leslie A ^b   Xie, Ze Xiong ^a   Lin, Qiu Hui ^a   Wang, Xia ^a   Xiao, Wen Hai ^a   Wang, Ying ^a   Zhou, Xiao ^a   Liu, Hong ^a   Li, Xia ^a   Ding, Ming Zhu ^a   Liu, Duo ^a   Zhang, Lu ^a   Liu, Bao Li ^a   Wu, Xiao Le ^a   Li, Fei Fei ^a   Dong, Xiu Tao ^a   Jia, Bin ^a   Zhang, Wen Zheng ^a   Jiang, Guo Zhen ^a   Liu, Yue ^a   Bai, Xue ^a   Song, Tian Qing ^a   Chen, Yan ^a   Zhou, Si Jie ^a   Zhu, Rui Ying ^a   Gao, Feng ^a   Kuang, Zheng ^b   Wang, Xuya ^b   Shen, Michael ^b   Yang, Kun ^c   Stracquadanio, Giovanni ^c,d   Richardson, Sarah M ^c   Lin, Yicong ^e   Wang, Lihui ^e   Walker, Roy ^f   Luo, Yisha ^f   Ma, Ping Sheng ^a   Yang, Huanming ^g,h   Cai, Yizhi ^f   Dai, Junbiao ^e   Bader, Joel S ^c   Boeke, Jef D ^b   Yuan, Ying Jin ^a   more..

^a TIANJIN UNIVERSITY   (China)

^b NEW YORK UNIVERSITY MEDICAL CENTER   (United States)

^c Johns Hopkins University School of Medicine   (United States)

^d UNIVERSITY OF ESSEX   (United Kingdom)

^e TSINGHUA UNIVERSITY   (China)

^f UNIVERSITY OF EDINBURGH   (United Kingdom)

^g BGI SHENZHEN   (China)

^h James D Watson Institute of Genome Sciences   (China)

Author keywords

[No Author keywords available]

Indexed keywords

ATP2 PROTEIN; DNA FRAGMENT; FIP1 PROTEIN; GENOMIC DNA; GREEN FLUORESCENT PROTEIN; PROTEIN; RED FLUORESCENT PROTEIN; SYNTHETIC DNA; TRANSFER RNA; UNCLASSIFIED DRUG;

CELLS AND CELL COMPONENTS; CHROMOSOME; EUKARYOTE; FITNESS; GENETIC ANALYSIS; GROWTH RATE; INSECT; POLYMERASE CHAIN REACTION; YEAST;

3' UNTRANSLATED REGION; AMPLICON; ARTICLE; BINDING SITE; CELL STRUCTURE; CHROMOSOME REARRANGEMENT; CONTROLLED STUDY; DILUTION; DNA EXTRACTION; DNA SEQUENCE; DNA SYNTHESIS; DOWN REGULATION; ENDOREDUPLICATION; GENE DUPLICATION; GENE EXPRESSION; GENE LOCUS; GENE MAPPING; GENE REARRANGEMENT; HOMOLOGOUS RECOMBINATION; KARYOTYPING; NONHUMAN; NUCLEOTIDE SEQUENCE; OPEN READING FRAME; PHENOTYPE; PLASMID; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; PROGENY; PROMOTER REGION; PULSED FIELD GEL ELECTROPHORESIS; RNA ANALYSIS; RNA SEQUENCE; SACCHAROMYCES CEREVISIAE; STOP CODON; WHOLE GENOME SEQUENCING; X CHROMOSOME; CHEMISTRY; CHROMOSOMAL MAPPING; FUNGAL GENOME; GENETICS; HIGH THROUGHPUT SEQUENCING; PROCEDURES; REPRODUCTIVE FITNESS; SYNTHETIC BIOLOGY; YEAST ARTIFICIAL CHROMOSOME;

EUKARYOTA;

BASE SEQUENCE; CHROMOSOMES, ARTIFICIAL, YEAST; GENE DUPLICATION; GENETIC FITNESS; GENOME, FUNGAL; HIGH-THROUGHPUT NUCLEOTIDE SEQUENCING; PHYSICAL CHROMOSOME MAPPING; SACCHAROMYCES CEREVISIAE; SYNTHETIC BIOLOGY;

EID: 85014820348     PISSN: 00368075     EISSN: 10959203     Source Type: Journal    
DOI: 10.1126/science.aaf4706     Document Type: Article

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