Circular permutation of a synthetic eukaryotic chromosome with the telomerator

Proceedings of the National Academy of Sciences of the United States of America

Volumn 111, Issue 48, 2014, Pages 17003-17010

  Mitchell, Leslie A ^a   Boeke, Jef D ^a  

^a NEW YORK UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Chromosome engineering; Sc2.0; Synthetic chromosome; Telomerator; Telomeric silencing

Indexed keywords

EUKARYOTA; SACCHAROMYCES CEREVISIAE;

CIRCULAR DNA; SACCHAROMYCES CEREVISIAE PROTEIN; SCEI PROTEIN, S CEREVISIAE; TYPE II SITE SPECIFIC DEOXYRIBONUCLEASE; URA3 PROTEIN, S CEREVISIAE;

BINDING SITE; GENE EXPRESSION REGULATION; GENETICS; METABOLISM; MOLECULAR GENETICS; NUCLEOTIDE SEQUENCE; PROCEDURES; PULSED FIELD GEL ELECTROPHORESIS; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SACCHAROMYCES CEREVISIAE; SEQUENCE HOMOLOGY; SYNTHETIC BIOLOGY; TELOMERE; YEAST ARTIFICIAL CHROMOSOME;

BASE SEQUENCE; BINDING SITES; CHROMOSOMES, ARTIFICIAL, YEAST; DEOXYRIBONUCLEASES, TYPE II SITE-SPECIFIC; DNA, CIRCULAR; ELECTROPHORESIS, GEL, PULSED-FIELD; GENE EXPRESSION REGULATION, FUNGAL; MOLECULAR SEQUENCE DATA; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; SACCHAROMYCES CEREVISIAE; SACCHAROMYCES CEREVISIAE PROTEINS; SEQUENCE HOMOLOGY, NUCLEIC ACID; SYNTHETIC BIOLOGY; TELOMERE;

EID: 84914145408     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1414399111     Document Type: Article

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