Freund's complete adjuvant effect on BALB/c mice: An insight into inflammation and oxidative stress after immunity challenge

Bratislava Medical Journal

Volumn 117, Issue 5, 2016, Pages 268-271

  Pohanka, M ^a,b   Vobornikova, I ^a   Fusek, J ^c  

^a UNIVERSITY OF DEFENCE   (Czech Republic)

^b MENDEL UNIVERSITY IN BRNO   (Czech Republic)

^c UNIVERSITY OF PARDUBICE   (Czech Republic)

Author keywords

Adjuvant; Arthritis; Immunity; Inflammation; glutathione; Oxidative stress; Vaccination

Indexed keywords

CASP3 PROTEIN, MOUSE; CASPASE 3; CYTOKINE; FREUND ADJUVANT; GLUTATHIONE; IMMUNOLOGICAL ADJUVANT; INTERLEUKIN 2; INTERLEUKIN 4; MALONALDEHYDE; THIOBARBITURIC ACID REACTIVE SUBSTANCE; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL; BAGG ALBINO MOUSE; DRUG EFFECTS; FEMALE; INFLAMMATION; LIVER; METABOLISM; MOUSE; OXIDATIVE STRESS; SKELETAL MUSCLE;

ADJUVANTS, IMMUNOLOGIC; ANIMALS; CASPASE 3; CYTOKINES; FEMALE; FREUND'S ADJUVANT; GLUTATHIONE; INFLAMMATION; INTERLEUKIN-2; INTERLEUKIN-4; LIVER; MALONDIALDEHYDE; MICE; MICE, INBRED BALB C; MUSCLE, SKELETAL; OXIDATIVE STRESS; THIOBARBITURIC ACID REACTIVE SUBSTANCES; TUMOR NECROSIS FACTOR-ALPHA;

EID: 85014816464     PISSN: 00069248     EISSN: 13360345     Source Type: Journal    
DOI: 10.4149/BLL_2016_052     Document Type: Article

References (21)

1. Toth LA, Dunlap AW, Olson GA, Hessler JR. An evalua tion of distress following intraperitoneal immunization with freund adjuvant in mice Lab Anim Sci 1989; 39 (2): 122-126.
2. Alter G, Sekaly RP. Beyond adjuvants: Antagonizing inflammation to enhance vaccine immunity. Vaccine 2015; 33: B55-B59.
3. Guruprasad B, Chaudhary P, Choedon T, Kumar VL. Art esunate ameliorates functional limitations in freund's complete adjuvant-induced monoarthritis in rat by maintaining oxidative homeostasis and inhibiting cox-2 expression. Inflammation 2015; 38 (3): 1028-1035.
4. Chang XY, He H, Zhu LP et al. Protective effect of apigenin on freund's complete adjuvant-induced arthritis in rats via inhibiting p2x7/nf-kappa b pathway. Chem-Biol Interact 2015; 236: 41-46.
5. Li R, Cai L, Hu CM, Wu TN, Li J. Expression of hedg ehog signal pathway in articular cartilage is associated with the severity of cartilage damage in rats with adjuvant-induced arthritis. J Inflamm (Lond) 2015; 12.
6. Huang WY, Dai SP, Chang YC, Sun WH. Acidosis mediat es the switching of g(s)-pka and g(i)-pkc epsilon dependence in prolonged hyperalgesia induced by inflammation. PLoS One 2015; 10 (5).
7. Kampman-van de Hoek E, Sakkas P, Gerrits WJJ, van den Borne J, van der Peet-Schwering CMC, Jansman AJM. Induced lung inflammation and dietary protein supply affect nitrogen retention and amino acid metabolism in growing pigs. Br J Nutr 2015; 113 (3): 414-425.
8. Suri A, Calderon B, Esparza TJ, Frederick K, Bittne r P, Unanue ER. Immunological reversal of autoimmune diabetes without hematopoietic replacement of beta cells. Science 2006; 311 (5768): 1778-1780.
9. Armentero MT, Levandis G, Nappi G, Bazzini E, Bland ini F. Peripheral inflammation and neuroprotection: Systemic pretreatment with complete freund's adjuvant reduces 6-hydroxydopamine toxicity in a rodent model of parkinson's disease. Neurobiol Dis 2006; 24 (3): 492-505.
10. Broderson JR. A retrospective review of lesions ass ociated with the use of freund's adjuvant. Lab Anim Sci 1989; 39 (5): 400-405.
11. Srivastava S, Singh P, Jha KK, Srivastava S, Khosa RL. Evaluation of anti-arthritic potential of the methanolic extract of the aerial parts of costus speciosus. J Ayurveda Integr Med 2012; 3 (4): 204-208.
12. Pohanka M. Caffeine alters oxidative homeostasis in the body of balb/c mice. Bratisl Med J 2014; 115 (11): 699-703.
13. Pohanka M, Sobotka J, Stetina R. Sulfur mustard ind uced oxidative stress and its alteration by epigallocatechin gallate. Toxicol Lett 2011; 201 (2): 105-109.
14. Pohanka M, Sobotka J, Jilkova M, Stetina R. Oxidati ve stress after sulfur mustard intoxication and its reduction by melatonin: Efficacy of antioxidant therapy during serious intoxication. Drug Chem Toxicol 2011; 34 (1): 85-91.
15. Castilhos LG, Rezer JFP, Ruchel JB et al. Effect of uncaria tomentosa extract on purinergic enzyme activities in lymphocytes of rats submitted to experimental adjuvant arthritis model. BMC Complement Altern Med 2015; 15.
16. Li R, Cai L, Hu CM, Wu TN, Li J. Expression of hedg ehog signal pathway in articular cartilage is associated with the severity of cartilage damage in rats with adjuvant-induced arthritis. J Inflamm (Lond) 2015; 12.
17. Pohanka M. Role of oxidative stress in infectious d iseases. A review. Folia Microbiol 2013; 58 (6): 503-513.
18. Pohanka M. Impact of melatonin on immunity: A revie w. Cent Eur J Med 2013; 8 (4): 369-376.
19. Yamada T, Abe M, Lee J et al. Muscle dysfunction as sociated with adjuvant-induced arthritis is prevented by antioxidant treatment. Skeletal Muscle 2015; 5.
20. Arora R, Kuhad A, Kaur IP, Chopra K. Curcumin loade d solid lipid nanoparticles ameliorate adjuvant-induced arthritis in rats. Eur J Pain 2015; 19 (7): 940-952.
21. Ali EAI, Barakat BM, Hassan R. Antioxidant and angi ostatic effect of spirulina platensis suspension in complete freund's adjuvant-induced arthritis in rats. PLoS One 2015; 10 (4).