Use of self-collected capillary blood samples for islet autoantibody screening in relatives: a feasibility and acceptability study

Diabetic Medicine

Volumn 34, Issue 7, 2017, Pages 934-937

  Liu, Y ^a   Rafkin, L E ^b   Matheson, D ^b   Henderson, C ^c   Boulware, D ^c   Besser, R E J ^d   Ferrara, C ^e   Yu, L ^f   Steck, A K ^f   Bingley, P J ^g  

^a KING'S COLLEGE LONDON   (United Kingdom)

^b UNIVERSITY OF MIAMI MILLER SCHOOL OF MEDICINE   (United States)

^c UNIVERSITY OF SOUTH FLORIDA   (United States)

^d UNIVERSITY OF OXFORD   (United Kingdom)

^e UNIVERSITY OF CALIFORNIA   (United States)

^f UNIVERSITY OF COLORADO SCHOOL OF MEDICINE   (United States)

^g UNIVERSITY OF BRISTOL   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

AUTOANTIBODY; GLUTAMATE DECARBOXYLASE ANTIBODY; INSULIN ANTIBODY; ISLET ANTIGEN 2 ANTIBODY; PANCREAS ISLET CELL ANTIBODY; UNCLASSIFIED DRUG; ZINC TRANSPORTER 8 ANTIBODY;

ADOLESCENT; ADULT; ANTIBODY SCREENING; ARTICLE; BLOOD ANALYSIS EQUIPMENT; BLOOD SAMPLING; CAPILLARY BLOOD; CAPILLARY TUBE; CHILD; FEASIBILITY STUDY; FEMALE; HUMAN; INSULIN DEPENDENT DIABETES MELLITUS; MAJOR CLINICAL STUDY; MALE; OUTPATIENT CARE; PANCREAS ISLET; RELATIVE; SELF CARE; VEIN PUNCTURE; ASYMPTOMATIC DISEASE; AUTOIMMUNE DISEASE; BLOOD; CAPILLARY; EARLY DIAGNOSIS; EVALUATION STUDY; FAMILY HEALTH; IMMUNOLOGY; MASS SCREENING; PATIENT ATTITUDE; PROCEDURES; RISK; UNITED KINGDOM;

ADOLESCENT; ADULT; ASYMPTOMATIC DISEASES; AUTOANTIBODIES; AUTOIMMUNE DISEASES; BLOOD SPECIMEN COLLECTION; CAPILLARIES; CHILD; DIABETES MELLITUS, TYPE 1; EARLY DIAGNOSIS; FAMILY HEALTH; FEASIBILITY STUDIES; FEMALE; HUMANS; ISLETS OF LANGERHANS; MALE; MASS SCREENING; PATIENT ACCEPTANCE OF HEALTH CARE; RISK; SELF CARE; UNITED KINGDOM;

EID: 85014779178     PISSN: 07423071     EISSN: 14645491     Source Type: Journal    
DOI: 10.1111/dme.13338     Document Type: Article

References (13)

1. Ziegler A, Rewers M, Simell O, Simell T, Lempainen J, Steck A et al. Seroconversion to multiple islet autoantibodies and risk of progression to diabetes in children. JAMA 2013; 309: 2473–2479.
2. Insel A, Dunne J, Atkinson M, Chiang J, Dabelea D, Gottlieb P et al. Staging Presymptomatic Type 1 Diabetes: A Scientific Statement of JDRF, the Endocrine Society, and the American Diabetes Association. Diabetes Care 2015; 38: 1964–1974.
3. Bazzigaluppi E, Bonfanti R, Bingley P, Bosi E, Bonifacio E. Capillary Whole Blood Measurement of Islet Autoantibodies. Diabetes Care 1999; 22: 275–279.
4. Siraj E, Rogers D, Gupta M, Reddy S. A simple screening method for individuals at risk of developing type 1 diabetes: Measurement of islet cell autoantibodies (GADA, IA-2A, and IAA) on dried capillary blood spots collected on filter paper. Horm Metab Res 2012; 44: 855–860.
5. Bingley P, Rafkin L, Matheson D, Steck A, Yu L, Henderson C et al. Use of Dried Capillary Blood Sampling for Islet Autoantibody Screening in Relatives: A Feasibility Study. Diabetes Technol Ther 2015; 17: 867–871.
6. Mahon J, Sosenko J, Rafkin-Mervis L, Lachin J, Thompson C, Bingley P et al. The TrialNet Natural History Study of the Development of Type 1 Diabetes: objectives, design, and initial results. Pediatr Diabetes 2009; 10: 97–104.
7. Yu L, Robles D, Abiru N, Kaur P, Rewers M, Kelemen K et al. Early expression of antiinsulin autoantibodies of humans and the NOD mouse: evidence for early determination of subsequent diabetes. Proc Natl Acad Sci USA 2000; 97: 1701–1706.
8. Yu L, Boulware D, Beam C, Hutton J, Wenzlau J, Greenbaum C et al. Zinc transporter-8 autoantibodies improve prediction of type 1 diabetes in relatives positive for the standard biochemical autoantibodies. Diabetes Care 2012; 35: 1213–1218.
9. Strebelow M, Schlosser M, Ziegler B, Rjasanowski I, Ziegler M. Karlsburg Type I diabetes risk study of a general population: frequencies and interactions of the four major Type I diabetes-associated autoantibodies studied in 9419 schoolchildren. Diabetologia 1999; 42: 661–670.
10. Raab J, Haupt F, Scholz M, Matzke C, Warncke K, Lange K et al. Capillary blood islet autoantibody screening for identifying pre-type 1 diabetes in the general population: design and initial results of the Fr1da study. BMJ Open 2016; 6: e011144.
11. Ziegler A, Haupt F, Scholz M, Weininger K, Wittich S, Löbner S et al. 3 Screen ELISA for High-Throughput Detection of Beta Cell Autoantibodies in Capillary Blood. Diabetes Technol Ther 2016; 18: 687–693.
12. Simmons K, Alkanani A, McDaniel K, Goyne C, Miao D, Zhao Z et al. Islet Autoantibody Measurements from Dried Blood Spots on Filter Paper Strongly Correlate to Serum Levels. PLoS One 2016; 11.
13. Ziegler A, Bonifacio E. Age-related islet autoantibody incidence in offspring of patients with type 1 diabetes. Diabetologia 2012; 55: 1937–1943.