Design principles of autocatalytic cycles constrain enzyme kinetics and force low substrate saturation at flux branch points

eLife

Volumn 6, Issue , 2017, Pages

  Barenholz, Uri ^a   Davidi, Dan ^a   Reznik, Ed ^b   Bar On, Yinon ^a   Antonovsky, Niv ^a   Noor, Elad ^c   Milo, Ron ^a  

^a WEIZMANN INSTITUTE OF SCIENCE   (Israel)

^b MEMORIAL SLOAN KETTERING CANCER CENTER   (United States)

^c ETH ZURICH   (Switzerland)

Author keywords

[No Author keywords available]

Indexed keywords

CARBON METABOLISM; CATALYSIS; ENZYME KINETICS; GENE OVEREXPRESSION; KINETIC PARAMETERS; METABOLITE; PROTEOMICS; ENZYMOLOGY; ESCHERICHIA COLI; GENE EXPRESSION REGULATION; GENETICS; KINETICS; METABOLIC FLUX ANALYSIS; METABOLISM;

CARBON;

CARBON; ESCHERICHIA COLI; GENE EXPRESSION REGULATION, BACTERIAL; GENE EXPRESSION REGULATION, ENZYMOLOGIC; KINETICS; METABOLIC FLUX ANALYSIS; METABOLIC NETWORKS AND PATHWAYS; PROTEOMICS;

EID: 85014611037     PISSN: None     EISSN: 2050084X     Source Type: Journal    
DOI: 10.7554/eLife.20667.001     Document Type: Article

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