Developmental pathways to adiposity begin before birth and are influenced by genotype, prenatal environment and epigenome

BMC Medicine

Volumn 15, Issue 1, 2017, Pages

  Lin, Xinyi ^a   Lim, Ives Yubin ^a,b   Wu, Yonghui ^a   Teh, Ai Ling ^a   Chen, Li ^a   Aris, Izzuddin M ^a   Soh, Shu E ^a,b   Tint, Mya Thway ^b   MacIsaac, Julia L ^c   Morin, Alexander M ^c   Yap, Fabian ^d   Tan, Kok Hian ^d   Saw, Seang Mei ^e,f,g   Kobor, Michael S ^c   Meaney, Michael J ^a,h,j   Godfrey, Keith M ⁱ   Chong, Yap Seng ^a,b,j   Holbrook, Joanna D ^a   Lee, Yung Seng ^a,b,j   Gluckman, Peter D ^a,k   Karnani, Neerja ^a,b   Agarwal, Pratibha ^j   Biswas, Arijit ^j   Bong, Choon Looi ^j   Broekman, Birit F P ^j   Cai, Shirong ^j   Chan, Jerry Kok Yen ^j   Chan, Yiong Huak ^j   Chee, Cornelia Yin Ing ^j   Chen, Helen ^j   Cheung, Yin Bun ^j   Chinnadurai, Amutha ^j   Chng, Chai Kiat ^j   Chong, Mary Foong Fong ^j   Chong, Shang Chee ^j   Chua, Mei Chien ^j   Fok, Doris ^j   Fortier, Marielle V ^j   Goh, Anne Eng Neo ^j   Goh, Yam Thiam Daniel ^j   Gooley, Joshua J ^j   Han, Wee Meng ^j   Hanson, Mark ^j   Henry, Christiani Jeyakumar ^j   Hsu, Chin Ying ^j   Kapur, Jeevesh ^j   Kwek, Kenneth ^j   Lau, Ivy Yee Man ^j   Lee, Bee Wah ^j   Lek, Ngee ^j   Lim, Sok Bee ^j   Magiati, Iliana ^j   Daniel, Lourdes Mary ^j   Ngo, Cheryl ^j   Niduvaje, Krishnamoorthy ^j   Pang, Wei Wei ^j   Qiu, Anqi ^j   Quah, Boon Long ^j   Rajadurai, Victor Samuel ^j   Rauff, Mary ^j   Rebello, Salome A ^j   Richmond, Jenny L ^j   Rifkin Graboi, Anne ^j   Shek, Lynette Pei Chi ^j   Sheppard, Allan ^j   Shuter, Borys ^j   Singh, Leher ^j   Stunkel, Walter ^j   Su, Lin Lin ^j   Teoh, Oon Hoe ^j   van Bever, Hugo P S ^j   van Dam, Rob M ^j   Wong, Inez Bik Yun ^j   Wong, P C ^j   Yeo, George Seow Heong ^j   more..

^a AGENCY FOR SCIENCE   (Singapore)

^b NATIONAL UNIVERSITY OF SINGAPORE   (Singapore)

^c UNIVERSITY OF BRITISH COLUMBIA   (Canada)

^d KK WOMEN'S AND CHILDREN'S HOSPITAL   (Singapore)

^e NATIONAL UNIVERSITY OF SINGAPORE   (Singapore)

^f SINGAPORE EYE RESEARCH INSTITUTE   (Singapore)

^g DUKE NUS MEDICAL SCHOOL   (Singapore)

^h DOUGLAS MENTAL HEALTH UNIVERSITY INSTITUTE   (Canada)

ⁱ UNIVERSITY OF SOUTHAMPTON   (United Kingdom)

^j NATIONAL UNIVERSITY HEALTH SYSTEM   (Singapore)

^k UNIVERSITY OF AUCKLAND   (New Zealand)

more..

Author keywords

Birth weight; DNA methylation; Epigenome wide association study; Offspring adiposity; Prenatal environment

Indexed keywords

GLUCOSE; UNSATURATED FATTY ACID;

ADULT; ANK3 GENE; ARTICLE; BIRTH WEIGHT; CACNA1G GENE; CDKN2B GENE; CHILDHOOD OBESITY; COHORT ANALYSIS; DNA METHYLATION; EPIGENETICS; FATTY ACID BLOOD LEVEL; FEMALE; GENE; GENE LOCUS; GENETIC ASSOCIATION; GENETIC RISK; GENOTYPE; GLUCOSE BLOOD LEVEL; HUMAN; IGDCC4 GENE; MAJOR CLINICAL STUDY; MALE; MATERNAL OBESITY; MIRLET7BHG GENE; NEWBORN; OBSERVATIONAL STUDY; P4HA3 GENE; PRENATAL DEVELOPMENT; PROSPECTIVE STUDY; SINGLE NUCLEOTIDE POLYMORPHISM; SMOKING; ZNF423 GENE; COMPLICATION; ENVIRONMENT; GENETICS; GENOME-WIDE ASSOCIATION STUDY; OBESITY;

ADIPOSITY; BIRTH WEIGHT; DNA METHYLATION; ENVIRONMENT; EPIGENOMICS; FEMALE; GENOME-WIDE ASSOCIATION STUDY; GENOTYPE; HUMANS; INFANT, NEWBORN; OBESITY; PROSPECTIVE STUDIES;

EID: 85014609630     PISSN: None     EISSN: 17417015     Source Type: Journal    
DOI: 10.1186/s12916-017-0800-1     Document Type: Article

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