CD169+ macrophages regulate PD-L1 expression via type I interferon and thereby prevent severe immunopathology after LCMV infection

Cell Death and Disease

Volumn 7, Issue 11, 2016, Pages

  Shaabani, Namir ^a,b,c   Duhan, Vikas ^a   Khairnar, Vishal ^a   Gassa, Asmae ^a   Ferrer Tur, Rita ^a   Häussinger, Dieter ^b   Recher, Mike ^d   Zelinskyy, Gennadiy ^a   Liu, Jia ^e   Dittmer, Ulf ^a   Trilling, Mirko ^a   Scheu, Stefanie ^b   Hardt, Cornelia ^a   Lang, Philipp A ^b   Honke, Nadine ^a,b   Lang, Karl S ^a,b  

^a UNIVERSITY HOSPITAL ESSEN   (Germany)

^b HEINRICH HEINE UNIVERSITY   (Germany)

^c SCRIPPS RESEARCH INSTITUTE   (United States)

^d UNIVERSITY HOSPITAL BASEL   (Switzerland)

^e HUAZHONG UNIVERSITY OF SCIENCE AND TECHNOLOGY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

CD8 ANTIGEN; INTERFERON; MESSENGER RNA; PROGRAMMED DEATH 1 LIGAND 1; SIALOADHESIN; CD274 PROTEIN, MOUSE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIVIRAL ACTIVITY; ARTICLE; CD8+ T LYMPHOCYTE; CONTROLLED STUDY; DISEASE SEVERITY; IMMUNOPATHOLOGY; INTERFERON PRODUCTION; LYMPH NODE; LYMPHOCYTIC CHORIOMENINGITIS VIRUS; MACROPHAGE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; REGULATORY MECHANISM; SPLEEN; UPREGULATION; VIRUS INFECTION; VIRUS REPLICATION; VIRUS TYPING; ANIMAL; C57BL MOUSE; CHRONIC DISEASE; CROSS PRESENTATION; IMMUNOLOGY; LIVER; LYMPHOCYTIC CHORIOMENINGITIS; METABOLISM; PATHOLOGY; PHYSIOLOGY; VIROLOGY;

ANIMALS; ANTIGENS, CD274; CD8-POSITIVE T-LYMPHOCYTES; CHRONIC DISEASE; CROSS-PRIMING; INTERFERON TYPE I; LIVER; LYMPH NODES; LYMPHOCYTIC CHORIOMENINGITIS; LYMPHOCYTIC CHORIOMENINGITIS VIRUS; MACROPHAGES; MICE, INBRED C57BL; SIALIC ACID BINDING IG-LIKE LECTIN 1; SPLEEN;

EID: 85014407892     PISSN: None     EISSN: 20414889     Source Type: Journal    
DOI: 10.1038/cddis.2016.350     Document Type: Article

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