Single-cell transcriptome conservation in cryopreserved cells and tissues

Genome Biology

Volumn 18, Issue 1, 2017, Pages

  Guillaumet Adkins, Amy ^a,b   Rodríguez Esteban, Gustavo ^a,b   Mereu, Elisabetta ^a,b   Mendez Lago, Maria ^a,b   Jaitin, Diego A ^c   Villanueva, Alberto ^d,e   Vidal, August ^f   Martinez Marti, Alex ^g,h,i   Felip, Enriqueta ^g,h,i   Vivancos, Ana ⁱ   Keren Shaul, Hadas ^c   Heath, Simon ^a,b   Gut, Marta ^a,b   Amit, Ido ^c   Gut, Ivo ^a,b   Heyn, Holger ^a,b  

^a CENTRE FOR GENOMIC REGULATION CRG   (Spain)

^b UNIVERSITAT POMPEU FABRA   (Spain)

^c WEIZMANN INSTITUTE OF SCIENCE   (Israel)

^d CATALAN INSTITUTE OF ONCOLOGY   (Spain)

^e Xenopat SL   (Spain)

^f HOSPITAL UNIVERSITARI DE BELLVITGE   (Spain)

^g HOSPITAL UNIVERSITARI VALL D HEBRON   (Spain)

^h UNIVERSITAT AUTÒNOMA DE BARCELONA   (Spain)

ⁱ VALL D HEBRON UNIVERSITY HOSPITAL   (Spain)

Author keywords

Conservation; Cryopreservation; MARS Seq; Patient derived orthotopic xenograft; PBMC; PDOX; Peripheral blood mononuclear cells; RNA sequencing; Single cell genomics; Smart seq2; Transcriptomics

Indexed keywords

TRANSCRIPTOME; RNA;

ADULT; ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CELLS; CONTROLLED STUDY; CRYOPRESERVATION; EMBRYO; FEMALE; GENETIC CONSERVATION; HUMAN; HUMAN CELL; MOUSE; NONHUMAN; RNA PROCESSING; RNA SEQUENCE; RNA TRANSCRIPTION; TISSUES; TRANSCRIPTOMICS; ANIMAL; CELL LINE; CLUSTER ANALYSIS; DISEASE MODEL; DNA SEQUENCE; GENE EXPRESSION PROFILING; GENETICS; NEOPLASM; PATHOLOGY; PROCEDURES; REPRODUCIBILITY; RNA STABILITY; SINGLE CELL ANALYSIS; XENOGRAFT;

ANIMALS; CELL LINE; CLUSTER ANALYSIS; CRYOPRESERVATION; DISEASE MODELS, ANIMAL; GENE EXPRESSION PROFILING; HETEROGRAFTS; HUMANS; MICE; NEOPLASMS; REPRODUCIBILITY OF RESULTS; RNA; RNA STABILITY; SEQUENCE ANALYSIS, DNA; SINGLE-CELL ANALYSIS; TRANSCRIPTOME;

EID: 85014353565     PISSN: 14747596     EISSN: 1474760X     Source Type: Journal    
DOI: 10.1186/s13059-017-1171-9     Document Type: Article

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