Perspectives on model forecasts of the 2014-2015 Ebola epidemic in West Africa: Lessons and the way forward

BMC Medicine

Volumn 15, Issue 1, 2017, Pages

  Chowell, Gerardo ^a,b   Viboud, Cécile ^b   Simonsen, Lone ^c,d   Merler, Stefano ^e   Vespignani, Alessandro ^f  

^a GEORGIA STATE UNIVERSITY   (United States)

^b NATIONAL INSTITUTES OF HEALTH   (United States)

^c UNIVERSITY OF COPENHAGEN   (Denmark)

^d GEORGE WASHINGTON UNIVERSITY   (United States)

^e FONDAZIONE BRUNO KESSLER   (Italy)

^f NORTHEASTERN UNIVERSITY   (United States)

Author keywords

Data sharing; Disease forecast; Ebola; Epidemic model; Exponential growth; Lessons learned; Polynomial growth; Sub exponential growth; West Africa

Indexed keywords

ACCURACY; AFRICA; ARTICLE; DATA ANALYSIS; DISEASE SEVERITY; EBOLA HEMORRHAGIC FEVER; EPIDEMIC; EPIDEMIOLOGICAL DATA; FORECASTING; HUMAN; INFECTION CONTROL; MATHEMATICAL MODEL; NONHUMAN; PREDICTION; PROCESS OPTIMIZATION; SENSITIVITY ANALYSIS; VIRUS TRANSMISSION; BIOLOGICAL MODEL; EPIDEMIOLOGY; HEMORRHAGIC FEVER, EBOLA; TRANSMISSION;

AFRICA, WESTERN; EPIDEMICS; EPIDEMIOLOGIC METHODS; FORECASTING; HEMORRHAGIC FEVER, EBOLA; HUMANS; MODELS, BIOLOGICAL;

EID: 85014099278     PISSN: None     EISSN: 17417015     Source Type: Journal    
DOI: 10.1186/s12916-017-0811-y     Document Type: Article

References (50)

1. Tomori O. Will Africa's future epidemic ride on forgotten lessons from the Ebola epidemic? BMC Med. 2015;13:116.
2. Kucharski A, Piot P. Containing Ebola virus infection in West Africa. Euro Surveill. 2014;19(36):20899.
3. World Health Organization. Ebola data and statistics. Ebola Situation Report - 30 March 2016. http://apps.who.int/gho/data/node.ebola-sitrep.ebola-country?lang=en. Accessed 1 June 2016.
4. Chretien JP, Riley S, George DB. Mathematical modeling of the West Africa Ebola epidemic. Elife. 2015;4.
5. Chowell G, Viboud C, Hyman JM, Simonsen L. The Western Africa ebola virus disease epidemic exhibits both global exponential and local polynomial growth rates. PLoS Curr. 2015;7.
6. McNamara LA, Schafer IJ, Nolen LD, Gorina Y, Redd JT, Lo T, Ervin E, Henao O, Dahl BA, Morgan O, et al. Ebola surveillance - Guinea, Liberia, and Sierra Leone. MMWR Suppl. 2016;65(3):35-43.
7. cmrivers/ebola. Data for the 2014 ebola outbeak in West Africa. GitHub. https://github.com/cmrivers/ebola. Accessed 16 May 2016.
8. The Western Africa Ebola Outbreak. The Centre for the Mathematical Modelling of Infectious Diseases. London School of Hygiene & Tropical Medicine. http://ntncmch.github.io/ebola/. Accessed 16 May 2016.
9. Nishiura H, Chowell G. Early transmission dynamics of Ebola virus disease (EVD), West Africa, March to August 2014. Euro Surveill. 2014;19(37).
10. WHO Ebola Response Team. Ebola virus disease in West Africa - the first 9 months of the epidemic and forward projections. N Engl J Med. 2014;371(16):1481-95.
11. Althaus CL. Estimating the reproduction number of Zaire ebolavirus (EBOV) during the 2014 outbreak in West Africa. PLoS Curr. 2014;6.
12. Gomes MF, Piontti AP, Rossi L, Chao D, Longini I, Halloran ME, Vespignani A. Assessing the international spreading risk associated with the 2014 West African Ebola outbreak. PLOS Curr. 2014;6.
13. Pandey A, Atkins KE, Medlock J, Wenzel N, Townsend JP, Childs JE, Nyenswah TG, Ndeffo-Mbah ML, Galvani AP. Strategies for containing Ebola in West Africa. Science. 2014;346(6212):991-5.
14. Meltzer MI, Atkins CY, Santibanez S, Knust B, Petersen BW, Ervin ED, Nichol ST, Damon IK, Washington ML. Estimating the future number of cases in the ebola epidemic - Liberia and Sierra leone, 2014-2015. MMWR Suppl. 2014;63:1-14.
15. Fisman D, Khoo E, Tuite A. Early epidemic dynamics of the west african 2014 ebola outbreak: estimates derived with a simple two-parameter model. PLoS Curr. 2014;6.
16. Achenbach J, Sun LH, Dennis B. The ominous math of the Ebola epidemic. The Washington Post. 2014. https://www.washingtonpost.com/national/health-science/the-ominous-math-of-the-ebola-epidemic/2014/10/09/3cad9e76-4fb2-11e4-8c24-487e92bc997b_story.html?utm_term=.d33fb8b27be2. Accessed 16 May 2016.
17. Viboud C, Simonsen L, Chowell G. A generalized-growth model to characterize the early ascending phase of infectious disease outbreaks. Epidemics. 2016;15:27-37.
18. Funk S, Knight GM, Jansen VA. Ebola: the power of behaviour change. Nature. 2014;515(7528):492.
19. Szendroi B, Csányi G. Polynomial epidemics and clustering in contact networks. Proc Biol Sci. 2004;271 Suppl 5:S364-6.
20. Anderson RM, May RM. Infectious diseases of humans. Oxford: Oxford University Press; 1991.
21. Chowell G, Viboud C, Simonsen L, Moghadas SM. Characterizing the reproduction number of epidemics with early sub-exponential growth dynamics. J R Soc Interface. 2016;13(123).
22. May RM, Anderson RM. Transmission dynamics of HIV infection. Nature. 1987;326(6109):137-42.
23. Colgate SA, Stanley EA, Hyman JM, Layne SP, Qualls C. Risk behavior-based model of the cubic growth of acquired immunodeficiency syndrome in the United States. Proc Natl Acad Sci U S A. 1989;86(12):4793-7.
24. Rothenberg R. A Reality of Its Own. In: Chowell G, Hyman JM, editors. Mathematical and Statistical Modeling for Emerging and Re-emerging Infectious Diseases. Basel: Springer; 2016.
25. Chowell G, Sattenspiel L, Bansal S, Viboud C. Mathematical models to characterize early epidemic growth: a review. Phys Life Rev. 2016;18:66-97.
26. Brauer F. Some simple epidemic models. Math Biosci Eng. 2006;3(1):1-15.
27. Salem D, Smith RJ. A mathematical model of Ebola Virus Disease: using sensitivity analysis to determine effective intervention targets. SCSC '16 Proceedings of the Summer Computer Simulation Conference. Article 3. Montreal. 2016.
28. Webb GF, Browne CJ. A model of the Ebola epidemics in West Africa incorporating age of infection. J Biol Dyn. 2016;10:18-30.
29. Balcan D, Hu H, Goncalves B, Bajardi P, Poletto C, Ramasco JJ, Paolotti D, Perra N, Tizzoni M, Van den Broeck W, et al. Seasonal transmission potential and activity peaks of the new influenza A(H1N1): a Monte Carlo likelihood analysis based on human mobility. BMC Med. 2009;7:45.
30. Merler S, Ajelli M, Fumanelli L, Gomes MF, Piontti AP, Rossi L, Chao DL, Longini Jr IM, Halloran ME, Vespignani A. Spatiotemporal spread of the 2014 outbreak of Ebola virus disease in Liberia and the effectiveness of non-pharmaceutical interventions: a computational modelling analysis. Lancet Infect Dis. 2015;15(2):204-11.
31. Ajelli M, Parlamento S, Bome D, Kebbi A, Atzori A, Frasson C, Putoto G, Carraro D, Merler S. The 2014 Ebola virus disease outbreak in Pujehun, Sierra Leone: epidemiology and impact of interventions. BMC Med. 2015;13:281.
32. Faye O, Boelle PY, Heleze E, Faye O, Loucoubar C, Magassouba N, Soropogui B, Keita S, Gakou T, el Bah HI, et al. Chains of transmission and control of Ebola virus disease in Conakry, Guinea, in 2014: an observational study. Lancet Infect Dis. 2015;15(3):320-6.
33. Nyenswah T, Blackley DJ, Freeman T, Lindblade KA, Arzoaquoi SK, Mott JA, Williams JN, Halldin CN, Kollie F, Laney AS, et al. Community quarantine to interrupt Ebola virus transmission - Mawah Village, Bong County, Liberia, August-October, 2014. MMWR Morb Mortal Wkly Rep. 2015;64(7):179-82.
34. Chowell G, Hincapia-Palacio D, Ospina J, Pell B, Tariq A, Dahal S, Moghadas S, Smirnova A, Simonsen L, Viboud C. Using phenomenological models to characterize transmissibility and forecast patterns and final burden of Zika epidemics. PLoS Curr. 2016;8.doi: 10.1371/currents.outbreaks.f14b2217c902f453d9320a43a35b9583.
35. Wallinga J, Lipsitch M. How generation intervals shape the relationship between growth rates and reproductive numbers. Proc Biol Sci. 2007;274(1609):599-604.
36. Nishiura H, Chowell G. The Effective Reproduction Number as a Prelude to Statistical Estimation of Time-dependent Epidemic Trends. In: Chowell G, Hyman JM, Bettencourt LMA, Castillo-Chavez C, editors. Mathematical and Statistical Estimation Approaches in Epidemiology. Rotterdam: Springer; 2009. p. 103-21.
37. Chowell G, Abdirizak F, Lee S, Lee J, Jung E, Nishiura H, Viboud C. Transmission characteristics of MERS and SARS in the healthcare setting: a comparative study. BMC Med. 2015;13:210.
38. Vera DM, Hora RA, Murillo A, Wong JF, Torre AJ, Wang D, Boulay D, Hancock K, Katz JM, Ramos M, et al. Assessing the impact of public health interventions on the transmission of pandemic H1N1 influenza a virus aboard a Peruvian navy ship. Influenza Other Respir Viruses. 2014;8(3):353-9.
39. White LF, Pagano M. Transmissibility of the influenza virus in the 1918 pandemic. PloS One. 2008;3(1), e1498.
40. Vynnycky E, Edmunds WJ. Analyses of the 1957 (Asian) influenza pandemic in the United Kingdom and the impact of school closures. Epidemiol Infect. 2008;136(2):166-79.
41. Cleaton JM, Viboud C, Simonsen L, Hurtado AM, Chowell G. Characterizing Ebola transmission patterns based on internet news reports. Clin Infect Dis. 2015;62(1):24-31.
42. Fasina F, Shittu A, Lazarus D, Tomori O, Simonsen L, Viboud C, Chowell G. Transmission dynamics and control of Ebola virus disease outbreak in Nigeria, July to September 2014. Euro Surveill. 2014;19(40):20920.
43. Schuster P. Ebola - challenge and revival of theoretical epidemiology: why extrapolations from early phases of epidemics are problematic. Complexity. 2015;20(5):7-12.
44. Yang W, Zhang W, Kargbo D, Yang R, Chen Y, Chen Z, Kamara A, Kargbo B, Kandula S, Karspeck A, et al. Transmission network of the 2014-2015 Ebola epidemic in Sierra Leone. J R Soc Interface. 2015;12(112).
45. International Ebola Response Team, Agua-Agum J, Ariyarajah A, Aylward B, Bawo L, Bilivogui P, Blake IM, Brennan RJ, Cawthorne A, Cleary E, et al. Exposure Patterns driving Ebola transmission in West Africa: a retrospective observational study. PLoS Med. 2016;13(11):e1002170.
46. Chretien JP, Rivers CM, Johansson MA. Make data sharing routine to prepare for public health emergencies. PLoS Med. 2016;13(8), e1002109.
47. Breman JG, Piot P, Johnson KM, White MK, Mbuyi M, Sureau P, Heymann DL, Van Nieuwenhove S, McCormick JB, Ruppol JP, et al. The epidemiology of Ebola hemorrhagic fever in Zaire, 1976. Bull World Health Organ. 1978;56(2):271-93.
48. Khan AS, Tshioko FK, Heymann DL, Le Guenno B, Nabeth P, Kerstiens B, Fleerackers Y, Kilmarx PH, Rodier GR, Nkuku O, et al. The reemergence of Ebola hemorrhagic fever, Democratic Republic of the Congo, 1995. Commission de Lutte contre les Epidemies a Kikwit. J Infect Dis. 1999;179 Suppl 1:S76-86.
49. Maganga GD, Kapetshi J, Berthet N, Kebela Ilunga B, Kabange F, Mbala Kingebeni P, Mondonge V, Muyembe JJ, Bertherat E, Briand S, et al. Ebola virus disease in the Democratic Republic of Congo. N Engl J Med. 2014;371(22):2083-91.
50. Centers for Disease Control and Prevention (CDC). Outbreak of Ebola hemorrhagic fever, Uganda, August 2000-January 2001. MMWR Morb Mortal Wkly Rep. 2001;50(5):73-7.