PREVENT-DM Comparative Effectiveness Trial of Lifestyle Intervention and Metformin

American Journal of Preventive Medicine

Volumn 52, Issue 6, 2017, Pages 788-797

  O'Brien, Matthew J ^a,b   Perez, Alberly ^b,c   Scanlan, Adam B ^d   Alos, Victor A ^b,c   Whitaker, Robert C ^c   Foster, Gary D ^e   Ackermann, Ronald T ^a   Ciolino, Jody D ^a   Homko, Carol ^c  

^a NORTHWESTERN UNIVERSITY   (United States)

^b Puentes de Salud Health Center   (United States)

^c TEMPLE UNIVERSITY   (United States)

^d UNIVERSITY OF PENNSYLVANIA   (United States)

^e Weight Watchers International   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

GLUCOSE; HEMOGLOBIN A1C; INSULIN; LIPID; METFORMIN; ANTIDIABETIC AGENT; GLYCOSYLATED HEMOGLOBIN;

ADULT; ARTICLE; BEHAVIOR CHANGE; BLOOD PRESSURE; CLINICAL EFFECTIVENESS; COMPARATIVE EFFECTIVENESS; CONTROLLED STUDY; DIABETES MELLITUS; DIET RESTRICTION; DIETARY INTAKE; DIZZINESS; DRUG EFFICACY; DRUG WITHDRAWAL; FEEDBACK SYSTEM; FEMALE; GASTROINTESTINAL SYMPTOM; GLUCOSE BLOOD LEVEL; HEADACHE; HEALTH AUXILIARY; HEALTH BEHAVIOR; HIGH RISK POPULATION; HISPANIC; HUMAN; IMPAIRED GLUCOSE TOLERANCE; LIFESTYLE MODIFICATION; MEDICAL CARE; MIDDLE AGED; PATIENT COMPLIANCE; PHYSICAL ACTIVITY; RANDOMIZED CONTROLLED TRIAL; TREATMENT DURATION; URBAN POPULATION; VERTIGO; WAIST CIRCUMFERENCE; WEIGHT CHANGE; WEIGHT REDUCTION; BODY WEIGHT LOSS; ETHNOLOGY; LIFESTYLE; STATISTICS AND NUMERICAL DATA;

FEMALE; GLYCATED HEMOGLOBIN A; HISPANIC AMERICANS; HUMANS; HYPOGLYCEMIC AGENTS; LIFE STYLE; METFORMIN; MIDDLE AGED; PREDIABETIC STATE; WAIST CIRCUMFERENCE; WEIGHT LOSS;

EID: 85013777317     PISSN: 07493797     EISSN: 18732607     Source Type: Journal    
DOI: 10.1016/j.amepre.2017.01.008     Document Type: Article

References (45)

1. Knowler, W., Barrett-Connor, E., Fowler, S., et al. Reduction in the incidence of type 2 diabetes with lifestyle intervention or metformin. N Engl J Med 346:6 (2002), 393–403, 10.1056/NEJMoa012512.
2. Ali, M.K., Echouffo-Tcheugui, J., Williamson, D.F., How effective were lifestyle interventions in real-world settings that were modeled on the Diabetes Prevention Program?. Health Aff (Millwood) 31:1 (2012), 67–75, 10.1377/hlthaff.2011.1009.
3. Dunkley, A.J., Bodicoat, D.H., Greaves, C.J., et al. Diabetes prevention in the real world: effectiveness of pragmatic lifestyle interventions for the prevention of type 2 diabetes and of the impact of adherence to guideline recommendations: a systematic review and meta-analysis. Diabetes Care 37:4 (2014), 922–923, 10.2337/dc13-2195.
4. Balk, E.M., Earley, A., Raman, G., Avendano, E.A., Pittas, A.G., Remington, P.L., Combined diet and physical activity promotion programs to prevent type 2 diabetes among persons at increased risk: a systematic review for the Community Preventive Services Task Force. Ann Intern Med 163:6 (2015), 437–451, 10.7326/M15-0452.
5. Albright, A.L., Gregg, E.W., Preventing type 2 diabetes in communities across the U.S.: the National Diabetes Prevention Program. Am J Prev Med 44:4 suppl (2013), S346–S351, 10.1016/j.amepre.2012.12.009.
6. Pear R. Medicare proposal takes aim at diabetes. New York Times. 2016; www.nytimes.com/2016/03/23/us/politics/medicare-proposal-takes-aim-at-diabetes.html?_r=0. Accessed May 16, 2016.
7. Ramachandran, A., Snehalatha, C., Mary, S., Mukesh, B., Bhaskar, A., Vijay, V., The Indian Diabetes Prevention Programme shows that lifestyle modification and metformin prevent type 2 diabetes in Asian Indian subjects with impaired glucose tolerance (IDPP-1). Diabetoogia 49:2 (2006), 289–297, 10.1007/s00125-005-0097-z.
8. Menke, A., Casagrande, S., Geiss, L., Cowie, C.C., Prevalence of and trends in diabetes among adults in the United States, 1988-2012. JAMA 314:10 (2015), 1021–1029, 10.1001/jama.2015.10029.
9. Venkat Narayan, K.M., Boyle, J.P., Thompson, T.J., Sorensen, S.W., Williamson, D.F., Lifetime risk for diabetes mellitus in the United States. JAMA 290:14 (2003), 1884–1890, 10.1001/jama.290.14.1884.
10. Ockene, I.S., Tellez, T.L., Rosal, M.C., et al. Outcomes of a Latino community-based intervention for the prevention of diabetes: the Lawrence Latino Diabetes Prevention Project. Am J Public Health 102:2 (2012), 336–342, 10.2105/AJPH.2011.300357.
11. Vincent, D., McEwen, M.M., Hepworth, J.T., Stump, C.S., The effects of a community-based, culturally tailored diabetes prevention intervention for high-risk adults of Mexican descent. Diabetes Educ 40:2 (2014), 202–213, 10.1177/0145721714521020.
12. Van Name, M.A., Camp, A.W., Magenheimer, E.A., et al. Effective translation of an intensive lifestyle intervention for Hispanic women with prediabetes in a community health center setting. Diabetes Care 39:4 (2016), 525–531, 10.2337/dc15-1899.
13. O'Brien, M.J., Squires, A.P., Bixby, R.A., Larson, S.C., Role development of community health workers: an examination of selection and training processes in the intervention literature. Am J Prev Med 37:6 Suppl 1 (2009), S262–S269, 10.1016/j.amepre.2009.08.011.
14. Katula, J.A., Vitolins, M.Z., Rosenberger, E.L., et al. Healthy Living Partnerships to Prevent Diabetes (HELP PD): design and methods. Contemp Clin Trials 31:1 (2010), 71–81, 10.1016/j.cct.2009.09.002.
15. Perez, A., Alos, V.A., Scanlan, A., et al. The rationale, design, and baseline characteristics of PREVENT-DM: a community-based comparative effectiveness trial of lifestyle intervention and metformin among Latinas with prediabetes. Contemp Clin Trials 45:Part B (2015), 320–327, 10.1016/j.cct.2015.10.011.
16. O'Brien, M.J., Halbert, C.H., Bixby, R., Pimentel, S., Shea, J.A., Community health worker intervention to decrease cervical cancer disparities in Hispanic women. J Gen Intern Med 25:11 (2010), 1186–1192, 10.1007/s11606-010-1434-6.
17. American Diabetes Association. Diabetes Risk Test. 2011; http://main.diabetes.org/dorg/PDFs/risk-test-paper-version.pdf. Accessed June 28, 2016.
18. Diabetes Prevention Program Research Group. The Diabetes Prevention Program (DPP) description of lifestyle intervention. Diabetes Care., 25(12), 2002, 2165–2171, 10.2337/diacare.25.12.2165.
19. Kramer, M.K., Kriska, A.M., Venditti, E.M., et al. Translating the Diabetes Prevention Program: a comprehensive model for prevention training and program delivery. Am J Prev Med 37:6 (2009), 505–511, 10.1016/j.amepre.2009.07.020.
20. O'Brien, M.J., Davey, A., Alos, V.A., Whitaker, R.C., Diabetes-related behaviors in Latinas and non-Latinas in California. Diabetes Care 36:2 (2013), 355–361, 10.2337/dc12-0548.
21. O'Brien, M.J., Shuman, S.J., Barrios, D.M., Alos, V.A., Whitaker, R.C., A qualitative study of acculturation and diabetes risk among urban immigrant Latinas: implications for diabetes prevention efforts. Diabetes Educ 40:5 (2014), 616–625, 10.1177/0145721714535992.
22. Salpeter, S.R., Buckley, N.S., Kahn, J.A., Salpeter, E.E., Meta-analysis: metformin treatment in persons at risk for diabetes mellitus. Am J Med 121:2 (2008), 149–157, 10.1016/j.amjmed.2007.09.016.
23. National Diabetes Education Program. Publications. 2014; http://ndep.nih.gov/publications/index.aspx. Accessed April 8, 2016.
24. Hamman, R.F., Wing, R.R., Edelstein, S.L., et al. Effect of weight loss with lifestyle intervention on risk of diabetes. Diabetes Care 29:9 (2006), 2102–2107, 10.2337/dc06-0560.
25. Lachin, J.M., Christophi, C.A., Edelstein, S.L., et al. Factors associated with diabetes onset during metformin versus placebo therapy in the diabetes prevention program. Diabetes 56:4 (2007), 1153–1159, 10.2337/db06-0918.
26. Mudaliar, U., Zabetian, A., Goodman, M., et al. Cardiometabolic risk factor changes observed in diabetes prevention programs in U.S. settings: a systematic review and meta-analysis. PLoS Med, 13(7), 2016, e1002095, 10.1371/journal.pmed.1002095.
27. O'Brien, M.J., Lee, J.Y., Carnethon, M.R., et al. Detecting dysglycemia using the 2015 United States Preventive Services Task Force screening criteria: a cohort analysis of community health center patients. PLoS Med, 13(7), 2016, e1002074, 10.1371/journal.pmed.1002074.
28. YMCA's Diabetes Prevention Program. Diabetes Prevention Program FACT SHEET. November, 2015, YMCA of the USA; 2015, Chicago, IL.
29. Look AHEAD Research Group. The Look AHEAD study: a description of the lifestyle intervention and the evidence supporting it. Obesity (Silver Spring, Md.) 14:5 (2006), 737–752, 10.1038/oby.2006.84.
30. Matthews, D., Hosker, J., Rudenski, A., Naylor, B., Treacher, D., Turner, R., Homeostasis model assessment: insulin resistance and β-cell function from fasting plasma glucose and insulin concentrations in man. Diabetologia 28:7 (1985), 412–419, 10.1007/BF00280883.
31. Little, R.R., Glycated hemoglobin standardization–National Glycohemoglobin Standardization Program (NGSP) perspective. Clin Chem Lab Med 41:9 (2003), 1191–1198, 10.1515/CCLM.2003.183.
32. O'Brien, M.J., Perez, A., Alos, V.A., et al. The feasibility, acceptability, and preliminary effectiveness of a Promotora-Led Diabetes Prevention Program (PL-DPP) in Latinas: a pilot study. Diabetes Educ 41:4 (2015), 485–494, 10.1177/0145721715586576.
33. Matts, J.P., Lachin, J.M., Properties of permuted-block randomization in clinical trials. Control Clin Trials 9:4 (1988), 327–344, 10.1016/0197-2456(88)90047-5.
34. Ackermann, R.T., Liss, D.T., Finch, E.A., et al. A randomized comparative effectiveness trial for preventing type 2 diabetes. Am J Public Health 105:11 (2015), 2328–2334, 10.2105/AJPH.2015.302641.
35. Kanaya, A.M., Herrington, D., Vittinghoff, E., et al. Understanding the high prevalence of diabetes in U.S. South Asians compared with four racial/ethnic groups: the MASALA and MESA studies. Diabetes Care 37:6 (2014), 1621–1628, 10.2337/dc13-2656.
36. West, D.S., Prewitt, T.E., Bursac, Z., Felix, H.C., Weight loss of black, white, and Hispanic men and women in the Diabetes Prevention Program. Obesity (Silver Spring) 16:6 (2008), 1413–1420, 10.1038/oby.2008.224.
37. Diabetes Prevention Program Research Group. Long-term safety, tolerability, and weight loss associated with metformin in the Diabetes Prevention Program Outcomes Study. Diabetes Care 35:4 (2012), 731–737, 10.2337/dc11-1299.
38. Ealovega, M.W., Tabaei, B.P., Brandle, M., Burke, R., Herman, W.H., Opportunistic screening for diabetes in routine clinical practice. Diabetes Care 27:1 (2004), 9–12, 10.2337/diacare.27.1.9.
39. Schneiderman, N., Llabre, M., Cowie, C.C., et al. Prevalence of diabetes among Hispanics/Latinos from diverse backgrounds: the Hispanic Community Health Study/Study of Latinos (HCHS/SOL). Diabetes Care 37:8 (2014), 2233–2239, 10.2337/dc13-2939.
40. Pew Hispanic Center. Statistical Portrait of Hispanics in the United States, 2013. http://assets.pewresearch.org/wp-content/uploads/sites/7/2015/05/2015-05-12_statistical-portrait-of-hispanics-in-the-united-states-2013_final.pdf. Accessed October 17, 2016.
41. Ackermann, R.T., Finch, E.A., Brizendine, E., Zhou, H., Marrero, D.G., Translating the Diabetes Prevention Program into the community. The DEPLOY Pilot Study. Am J Prev Med 35:4 (2008), 357–363, 10.1016/j.amepre.2008.06.035.
42. Ackermann, R.T., Finch, E.A., Schmidt, K.K., et al. Rationale, design, and baseline characteristics of a community-based comparative effectiveness trial to prevent type 2 diabetes in economically disadvantaged adults: The RAPID Study. Contemp Clin Trials 37:1 (2014), 1–9, 10.1016/j.cct.2013.10.003.
43. Katula, J.A., Vitolins, M.Z., Rosenberger, E.L., et al. One-year results of a community-based translation of the diabetes prevention program. Diabetes Care 34:7 (2011), 1451–1457, 10.2337/dc10-2115.
44. Song, X., Qiu, M., Zhang, X., et al. Gender-related affecting factors of prediabetes on its 10-year outcome. BMJ Open Diabetes Res Care, 4, 2016, e000169, 10.1136/bmjdrc-2015-000169.
45. CDC. National Diabetes Prevention Program: Registry of Recognized Programs. 2016; https://nccd.cdc.gov/DDT_DPRP/State.aspx?STATE=ALL. Accessed April 15, 2016.