Maternal common variant rs2305957 spanning PLK4 is associated with blastocyst formation and early recurrent miscarriage

Fertility and Sterility

Volumn 107, Issue 4, 2017, Pages 1034-1040.e5

  Zhang, Qian ^a,b,c,d   Li, Guangyu ^a,b,c,d   Zhang, Lei ^a,b,c,d   Sun, Xiaohe ^a,b,c,d   Zhang, Dandan ^a,b,c,d   Lu, Juanjuan ^a,b,c,d   Ma, Jinlong ^a,b,c,d   Yan, Junhao ^a,b,c,d   Chen, Zi Jiang ^a,b,c,d,e,f  

^a SHANDONG PROVINCIAL HOSPITAL AFFILIATED TO SHANDONG UNIVERSITY   (China)

^b NATIONAL RESEARCH CENTER FOR ASSISTED REPRODUCTIVE TECHNOLOGY AND REPRODUCTIVE GENETICS   (China)

^c SHANDONG UNIVERSITY   (China)

^d Shandong Provincial Key Laboratory of Biomedical Polymers   (China)

^e SHANGHAI JIAO TONG UNIVERSITY SCHOOL OF MEDICINE   (China)

^f Shanghai Key Laboratory for Assisted Reproduction and Reproductive Genetics   (China)

Author keywords

Aneuploidy; blastocyst formation; early recurrent miscarriage; infertility; rs2305957

Indexed keywords

POLO LIKE KINASE 4; PLK4 PROTEIN, HUMAN; PROTEIN SERINE THREONINE KINASE;

ADULT; ALLELE; ARTICLE; BLASTOCYST; CHINESE; CONTROLLED STUDY; EMBRYO DEVELOPMENT; FEMALE; FEMALE INFERTILITY; GENE FREQUENCY; GENETIC ASSOCIATION STUDY; GENETIC VARIABILITY; GENOTYPE; HIGH RESOLUTION MELTING ANALYSIS; HUMAN; IN VITRO FERTILIZATION; LIVE BIRTH; MAJOR CLINICAL STUDY; PHENOTYPE; PRIORITY JOURNAL; SPONTANEOUS ABORTION; UNIVERSITY HOSPITAL; ABORTION, HABITUAL; ADVERSE EFFECTS; CASE CONTROL STUDY; CHINA; EMBRYO TRANSFER; ENZYMOLOGY; GENETIC PREDISPOSITION; GENETICS; HETEROZYGOTE; HOMOZYGOTE; INFERTILITY, FEMALE; NIDATION; PATHOLOGY; PATHOPHYSIOLOGY; PREGNANCY; RISK FACTOR; SINGLE NUCLEOTIDE POLYMORPHISM; TREATMENT OUTCOME; YOUNG ADULT;

ABORTION, HABITUAL; ADULT; BLASTOCYST; CASE-CONTROL STUDIES; CHINA; EMBRYO IMPLANTATION; EMBRYO TRANSFER; EMBRYONIC DEVELOPMENT; FEMALE; FERTILIZATION IN VITRO; GENE FREQUENCY; GENETIC ASSOCIATION STUDIES; GENETIC PREDISPOSITION TO DISEASE; HETEROZYGOTE; HOMOZYGOTE; HOSPITALS, UNIVERSITY; HUMANS; INFERTILITY, FEMALE; LIVE BIRTH; PHENOTYPE; POLYMORPHISM, SINGLE NUCLEOTIDE; PREGNANCY; PROTEIN-SERINE-THREONINE KINASES; RISK FACTORS; TREATMENT OUTCOME; YOUNG ADULT;

EID: 85013628658     PISSN: 00150282     EISSN: 15565653     Source Type: Journal    
DOI: 10.1016/j.fertnstert.2017.01.006     Document Type: Article

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