Application of Whole Exome Sequencing in the Clinical Diagnosis and Management of Inherited Cardiovascular Diseases in Adults

Circulation: Cardiovascular Genetics

Volumn 10, Issue 1, 2017, Pages

  Seidelmann, Sara B ^a,b,c,d   Smith, Emily ^a,b   Subrahmanyan, Lakshman ^a,b   Dykas, Daniel ^a   Ziki, Maen D Abou ^a   Azari, Bani ^a   Hannah Shmouni, Fady ^b   Jiang, Yuexin ^e,f   Akar, Joseph G ^a   Marieb, Mark ^a   Jacoby, Daniel ^a   Bale, Allen E ^a   Lifton, Richard P ^a   Mani, Arya ^a,b  

^a YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b Yale Program for Cardiovascular Genetics   (United States)

^c Division of Cardiovascular Medicine   (United States)

^d Division of Cardiac Imaging   (United States)

^e BRIGHAM AND WOMEN S HOSPITAL   (United States)

^f FUWAI HOSPITAL   (China)

Author keywords

arrhythmia; cardiomyopathy; genetics; sudden cardiac death

Indexed keywords

GENOMIC DNA;

ADULT; ARTICLE; CARDIOVASCULAR DISEASE; CARDIOVASCULAR RISK; CATECHOLAMINERGIC POLYMORPHIC VENTRICULAR TACHYCARDIA; CONGESTIVE CARDIOMYOPATHY; CONTROLLED STUDY; EHLERS DANLOS SYNDROME; FEMALE; GENETIC SCREENING; HEART FUNCTION; HEART RIGHT VENTRICLE DYSPLASIA; HEART VENTRICLE ARRHYTHMIA; HUMAN; HYPERTROPHIC CARDIOMYOPATHY; LONG QT SYNDROME; MAJOR CLINICAL STUDY; MALE; MARFAN SYNDROME; NONISCHEMIC CARDIOMYOPATHY; PRIORITY JOURNAL; QT PROLONGATION; REAL TIME POLYMERASE CHAIN REACTION; RESTRICTIVE CARDIOMYOPATHY; SUDDEN CARDIAC DEATH; WHOLE EXOME SEQUENCING; CARDIOVASCULAR DISEASES; DEATH, SUDDEN, CARDIAC; EXOME; GENETIC ASSOCIATION STUDY; GENETIC DATABASE; GENETIC PREDISPOSITION; GENETIC VARIATION; GENETICS; HEREDITY; HIGH THROUGHPUT SEQUENCING; MIDDLE AGED; MORTALITY; PEDIGREE; PHENOTYPE; PREDICTIVE VALUE; PROGNOSIS; RISK FACTOR;

ADULT; CARDIOVASCULAR DISEASES; DATABASES, GENETIC; DEATH, SUDDEN, CARDIAC; EXOME; FEMALE; GENETIC ASSOCIATION STUDIES; GENETIC PREDISPOSITION TO DISEASE; GENETIC VARIATION; HEREDITY; HIGH-THROUGHPUT NUCLEOTIDE SEQUENCING; HUMANS; MALE; MIDDLE AGED; PEDIGREE; PHENOTYPE; PREDICTIVE VALUE OF TESTS; PROGNOSIS; RISK FACTORS;

EID: 85013421165     PISSN: 1942325X     EISSN: 19423268     Source Type: Journal    
DOI: 10.1161/CIRCGENETICS.116.001573     Document Type: Article

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