메뉴 건너뛰기




Volumn 106, Issue 4, 2011, Pages 655-664

Common variants in the haemostatic gene pathway contribute to risk of early-onset myocardial infarction in the Italian population

Author keywords

Association study; Common genetic variants; Early onset myocardial infarction; Genetic risk score; Haemostatic gene pathway

Indexed keywords

ALANINE; ARGININE; ASPARTIC ACID; GLUTAMIC ACID; GLYCINE; HISTIDINE; LEUCINE; METHIONINE; PHENYLALANINE; PROLINE; SERINE; THREONINE; VALINE;

EID: 80053215612     PISSN: 03406245     EISSN: None     Source Type: Journal    
DOI: 10.1160/TH11-04-0247     Document Type: Article
Times cited : (24)

References (42)
  • 1
    • 0141885294 scopus 로고    scopus 로고
    • From vulnerable plaque to vulnerable patient: A call for new definitions and risk assessment strategies: Part I
    • Naghavi M, Libby P, Falk E, et al. From vulnerable plaque to vulnerable patient: a call for new definitions and risk assessment strategies: Part I. Circulation 2003; 108: 1664-1672.
    • (2003) Circulation , vol.108 , pp. 1664-1672
    • Naghavi, M.1    Libby, P.2    Falk, E.3
  • 2
    • 0032513756 scopus 로고    scopus 로고
    • Association of fibrinogen, C-reactive protein, albumin, or leukocyte count with coronary heart disease: Meta-analyses of prospective studies
    • Danesh J, Collins R, Appleby P, et al. Association of fibrinogen, C-reactive protein, albumin, or leukocyte count with coronary heart disease: meta-analyses of prospective studies. J Am Med Assoc 1998; 279: 1477-1482.
    • (1998) J Am Med Assoc , vol.279 , pp. 1477-1482
    • Danesh, J.1    Collins, R.2    Appleby, P.3
  • 3
    • 3242662502 scopus 로고    scopus 로고
    • Tissue plasminogen activator antigen and D-dimer as markers for atherothrombotic risk among healthy postmenopausal women
    • Pradhan AD, LaCroix AZ, Langer RD, et al. Tissue plasminogen activator antigen and D-dimer as markers for atherothrombotic risk among healthy postmenopausal women. Circulation 2004; 110: 292-300.
    • (2004) Circulation , vol.110 , pp. 292-300
    • Pradhan, A.D.1    Lacroix, A.Z.2    Langer, R.D.3
  • 4
    • 30944441643 scopus 로고    scopus 로고
    • Which hemostatic markers add to the predictive value of conventional risk factors for coronary heart disease and ischemic stroke? The Caerphilly Study
    • Smith A, Patterson C, Yarnell J, et al. Which hemostatic markers add to the predictive value of conventional risk factors for coronary heart disease and ischemic stroke? The Caerphilly Study. Circulation 2005; 112: 3080-3087.
    • (2005) Circulation , vol.112 , pp. 3080-3087
    • Smith, A.1    Patterson, C.2    Yarnell, J.3
  • 5
    • 0024529259 scopus 로고
    • Mortality and causes of death in Dutch haemophiliacs, 1973-86
    • Rosendaal FR, Varekamp I, Smit C, et al. Mortality and causes of death in Dutch haemophiliacs, 1973-86. Br J Haematol 1989; 71: 71-76.
    • (1989) Br J Haematol , vol.71 , pp. 71-76
    • Rosendaal, F.R.1    Varekamp, I.2    Smit, C.3
  • 6
    • 0028838605 scopus 로고
    • Mortality in patients with hemophilia: Changes in a Dutch population from 1986 to 1992 and 1973 to 1986
    • Triemstra M, Rosendaal FR, Smit C, et al. Mortality in patients with hemophilia: changes in a Dutch population from 1986 to 1992 and 1973 to 1986. Ann Intern Med 1995; 123: 823-827.
    • (1995) Ann Intern Med , vol.123 , pp. 823-827
    • Triemstra, M.1    Rosendaal, F.R.2    Smit, C.3
  • 7
    • 0023903660 scopus 로고
    • Cause of death in hemophilia A patients in the United States from 1968 to 1979
    • Aronson DL. Cause of death in hemophilia A patients in the United States from 1968 to 1979. Am J Hematol 1988; 27: 7-12.
    • (1988) Am J Hematol , vol.27 , pp. 7-12
    • Aronson, D.L.1
  • 8
    • 17144373675 scopus 로고    scopus 로고
    • Homozygosity for factor V Leiden leads to enhanced thrombosis and atherosclerosis in mice
    • Eitzman DT, Westrick RJ, Shen Y, et al. Homozygosity for factor V Leiden leads to enhanced thrombosis and atherosclerosis in mice. Circulation 2005; 111: 1822-1825.
    • (2005) Circulation , vol.111 , pp. 1822-1825
    • Eitzman, D.T.1    Westrick, R.J.2    Shen, Y.3
  • 9
    • 33745014423 scopus 로고    scopus 로고
    • Common genetic variation in five thrombosis genes and relations to plasma hemostatic protein level and cardiovascular disease risk
    • Kathiresan S, Yang Q, Larson MG, et al. Common genetic variation in five thrombosis genes and relations to plasma hemostatic protein level and cardiovascular disease risk. Arterioscler Thromb Vasc Biol 2006; 26: 1405-1412.
    • (2006) Arterioscler Thromb Vasc Biol , vol.26 , pp. 1405-1412
    • Kathiresan, S.1    Yang, Q.2    Larson, M.G.3
  • 10
    • 33645555323 scopus 로고    scopus 로고
    • Multi-locus candidate gene polymorphisms and risk of myocardial infarction: A population-based, prospective genetic analysis
    • Zee RYL, Cook NR, Cheng S, et al. Multi-locus candidate gene polymorphisms and risk of myocardial infarction: a population-based, prospective genetic analysis. J Thromb Haemost 2006; 4: 341-348.
    • (2006) J Thromb Haemost , vol.4 , pp. 341-348
    • Zee, R.Y.L.1    Cook, N.R.2    Cheng, S.3
  • 11
    • 37549055807 scopus 로고    scopus 로고
    • Variation in 24 hemostatic genes and associations with non-fatal myocardial infarction and ischemic stroke
    • Smith NL, Bis JC, Biagiotti S, et al. Variation in 24 hemostatic genes and associations with non-fatal myocardial infarction and ischemic stroke. J Thromb Haemost 2008; 6: 45-53.
    • (2008) J Thromb Haemost , vol.6 , pp. 45-53
    • Smith, N.L.1    Bis, J.C.2    Biagiotti, S.3
  • 12
    • 34247144499 scopus 로고    scopus 로고
    • Nonvalidation of reported genetic risk factors for acute coronary syndrome in a large-scale replication study
    • Morgan TM, Krumholz HM, Lifton RP, et al. Nonvalidation of reported genetic risk factors for acute coronary syndrome in a large-scale replication study. J Am Med Assoc 2007; 297: 1551-1561.
    • (2007) J Am Med Assoc , vol.297 , pp. 1551-1561
    • Morgan, T.M.1    Krumholz, H.M.2    Lifton, R.P.3
  • 13
    • 37549058754 scopus 로고    scopus 로고
    • Association of gene variants with incident myocardial infarction in the Cardiovascular Health Study
    • Shiffman D, O'Meara ES, Bare LA, et al. Association of gene variants with incident myocardial infarction in the Cardiovascular Health Study. Arterioscler Thromb Vasc Biol 2008; 28: 173-179.
    • (2008) Arterioscler Thromb Vasc Biol , vol.28 , pp. 173-179
    • Shiffman, D.1    O'Meara, E.S.2    Bare, L.A.3
  • 14
    • 42149120675 scopus 로고    scopus 로고
    • Polymorphisms in coagulation factors and the risk of recurrent cardiovascular events in men after a first myocardial infarction
    • van der Krabben MD, Rosendaal FR, van der Bom JG, et al. Polymorphisms in coagulation factors and the risk of recurrent cardiovascular events in men after a first myocardial infarction. J Thromb Haemost 2008; 6: 720-725.
    • (2008) J Thromb Haemost , vol.6 , pp. 720-725
    • van der Krabben, M.D.1    Rosendaal, F.R.2    van der Bom, J.G.3
  • 15
    • 0037442235 scopus 로고    scopus 로고
    • Genetic associations in large versus small studies: An empirical assessment
    • Ioannidis JP, Trikalinos TA, Ntzani EE, et al. Genetic associations in large versus small studies: an empirical assessment. Lancet 2003; 361: 567-571.
    • (2003) Lancet , vol.361 , pp. 567-571
    • Ioannidis, J.P.1    Trikalinos, T.A.2    Ntzani, E.E.3
  • 17
    • 33344478392 scopus 로고    scopus 로고
    • Seven haemostatic gene polymorphisms in coronary disease: Meta-analysis of 66,155 cases and 91,307 controls
    • Ye Z, Liu EHC, Higgins JPT, et al. Seven haemostatic gene polymorphisms in coronary disease: meta-analysis of 66,155 cases and 91,307 controls. Lancet 2006; 367: 651-658.
    • (2006) Lancet , vol.367 , pp. 651-658
    • Ye, Z.1    Liu, E.H.C.2    Higgins, J.P.T.3
  • 18
    • 78649348682 scopus 로고    scopus 로고
    • The association of factor V Leiden with myocardial infarction is replicated in 1880 patients with premature disease
    • Mannucci PM, Asselta R, Duga S, et al. The association of factor V Leiden with myocardial infarction is replicated in 1880 patients with premature disease. J Thromb Haemost 2010; 8: 2116-2121.
    • (2010) J Thromb Haemost , vol.8 , pp. 2116-2121
    • Mannucci, P.M.1    Asselta, R.2    Duga, S.3
  • 19
    • 0037418247 scopus 로고    scopus 로고
    • No evidence of association between prothrombotic gene polymorphisms and the development of acute myocardial infarction at a young age
    • Atherosclerosis, Thrombosis, and Vascular Biology Italian Study Group
    • Atherosclerosis, Thrombosis, and Vascular Biology Italian Study Group. No evidence of association between prothrombotic gene polymorphisms and the development of acute myocardial infarction at a young age. Circulation 2003; 107: 1117-1122.
    • (2003) Circulation , vol.107 , pp. 1117-1122
  • 20
    • 70749096913 scopus 로고    scopus 로고
    • Genome-wide association of early-onset myocardial infarction with single nucleotide polymorphisms and copy number variants
    • Kathiresan S, Voight BF, Purcell S, et al. Genome-wide association of early-onset myocardial infarction with single nucleotide polymorphisms and copy number variants. Nat Genet 2009; 41: 334-341.
    • (2009) Nat Genet , vol.41 , pp. 334-341
    • Kathiresan, S.1    Voight, B.F.2    Purcell, S.3
  • 21
    • 34548292504 scopus 로고    scopus 로고
    • PLINK: A tool set for whole-genome association and population-based linkage analyses
    • Purcell S, Neale B, Todd-Brown K, et al. PLINK: a tool set for whole-genome association and population-based linkage analyses. Am J Hum Genet 2007; 81: 559-575.
    • (2007) Am J Hum Genet , vol.81 , pp. 559-575
    • Purcell, S.1    Neale, B.2    Todd-Brown, K.3
  • 22
  • 23
    • 0001377483 scopus 로고
    • Statistical methods in cancer research: The design and analysis of cohort studies
    • Breslow NE, Day NE. Statistical methods in cancer research: The design and analysis of cohort studies. IARC Sci Publ 1987; 82: 289-302.
    • (1987) IARC Sci Publ , vol.82 , pp. 289-302
    • Breslow, N.E.1    Day, N.E.2
  • 24
    • 13444269543 scopus 로고    scopus 로고
    • Haploview: Analysis and visualization of LD and haplotype maps
    • Barrett JC, Fry B, Maller J, et al. Haploview: analysis and visualization of LD and haplotype maps. Bioinformatics 2005; 21: 263-265.
    • (2005) Bioinformatics , vol.21 , pp. 263-265
    • Barrett, J.C.1    Fry, B.2    Maller, J.3
  • 25
    • 61449255235 scopus 로고    scopus 로고
    • Risk prediction of prevalent diabetes in a Swiss population using a weighted genetic score - the CoLaus Study
    • Lin X, Song K, Lim N, et al. Risk prediction of prevalent diabetes in a Swiss population using a weighted genetic score - the CoLaus Study. Diabetologia 2009; 52: 600-608.
    • (2009) Diabetologia , vol.52 , pp. 600-608
    • Lin, X.1    Song, K.2    Lim, N.3
  • 26
    • 33748804424 scopus 로고    scopus 로고
    • A tutorial on statistical methods for population association studies
    • Balding DJ. A tutorial on statistical methods for population association studies. Nat Rev Genet 2006; 7: 781-791.
    • (2006) Nat Rev Genet , vol.7 , pp. 781-791
    • Balding, D.J.1
  • 27
    • 0016703755 scopus 로고
    • Effects of calcium ion and covalent crosslinking on formation and elasticity of fibrin cells
    • Shen LL, Hermans J, McDonagh J, et al. Effects of calcium ion and covalent crosslinking on formation and elasticity of fibrin cells. Thromb Res 1975; 6: 255-265.
    • (1975) Thromb Res , vol.6 , pp. 255-265
    • Shen, L.L.1    Hermans, J.2    McDonagh, J.3
  • 28
    • 34247137276 scopus 로고    scopus 로고
    • Factor XIII Val34Leu variant and the risk of myocardial infarction: A meta-analysis
    • Shafey M, Anderson JL, Scarvelis D, et al. Factor XIII Val34Leu variant and the risk of myocardial infarction: a meta-analysis. Thromb Haemost 2007; 97: 635-641.
    • (2007) Thromb Haemost , vol.97 , pp. 635-641
    • Shafey, M.1    Anderson, J.L.2    Scarvelis, D.3
  • 29
    • 0029790055 scopus 로고    scopus 로고
    • The endothelial cell protein C receptor augments protein C activation by the thrombin-thrombomodulin complex
    • Stearns-Kurosawa DJ, Kurosawa S, Mollica JS, et al. The endothelial cell protein C receptor augments protein C activation by the thrombin-thrombomodulin complex. Proc Natl Acad Sci USA 1996; 93: 10212-10216.
    • (1996) Proc Natl Acad Sci USA , vol.93 , pp. 10212-10216
    • Stearns-Kurosawa, D.J.1    Kurosawa, S.2    Mollica, J.S.3
  • 30
    • 50849093562 scopus 로고    scopus 로고
    • Endothelial protein C receptor polymorphisms and risk of myocardial infarction
    • Medina P, Navarro S, Corral J, et al. Endothelial protein C receptor polymorphisms and risk of myocardial infarction. Haematologica 2008; 93: 1358-1363.
    • (2008) Haematologica , vol.93 , pp. 1358-1363
    • Medina, P.1    Navarro, S.2    Corral, J.3
  • 31
    • 78649735165 scopus 로고    scopus 로고
    • Genome-wide association study identifies novel loci for plasma levels of protein C: The ARIC study
    • Tang W, Basu S, Kong X, et al. Genome-wide association study identifies novel loci for plasma levels of protein C: the ARIC study. Blood 2010; 116: 5032-5036.
    • (2010) Blood , vol.116 , pp. 5032-5036
    • Tang, W.1    Basu, S.2    Kong, X.3
  • 32
    • 79955658114 scopus 로고    scopus 로고
    • High levels of protein C are determined by PROCR haplotype 3
    • Pintao MC, Roshani S, DE Visser MC, et al. High levels of protein C are determined by PROCR haplotype 3. J Thromb Haemost 2011; 9: 969-976.
    • (2011) J Thromb Haemost , vol.9 , pp. 969-976
    • Pintao, M.C.1    Roshani, S.2    de Visser, M.C.3
  • 33
    • 52449099245 scopus 로고    scopus 로고
    • PROC, PROCR and PROS1 polymorphisms, plasma anticoagulant phenotypes, and risk of cardiovascular disease and mortality in older adults: The Cardiovascular Health Study
    • Reiner AP, Carty CL, Jenny NS, et al. PROC, PROCR and PROS1 polymorphisms, plasma anticoagulant phenotypes, and risk of cardiovascular disease and mortality in older adults: the Cardiovascular Health Study. J Thromb Haemost 2008; 6: 1625-1632.
    • (2008) J Thromb Haemost , vol.6 , pp. 1625-1632
    • Reiner, A.P.1    Carty, C.L.2    Jenny, N.S.3
  • 34
    • 0842307339 scopus 로고    scopus 로고
    • A haplotype of the EPCR gene is associated with increased plasma levels of sEPCR and is a candidate risk factor for thrombosis
    • Saposnik B, Reny JL, Gaussem P, et al. A haplotype of the EPCR gene is associated with increased plasma levels of sEPCR and is a candidate risk factor for thrombosis. Blood 2004; 103: 1311-1318.
    • (2004) Blood , vol.103 , pp. 1311-1318
    • Saposnik, B.1    Reny, J.L.2    Gaussem, P.3
  • 35
    • 77950217693 scopus 로고    scopus 로고
    • Novel associations of multiple genetic loci with plasma levels of factor VII, factor VIII, and von Willebrand factor: The CHARGE (Cohorts for Heart and Aging Research in Genome Epidemiology) Consortium
    • Smith NL, Chen MH, Dehghan A, et al. Novel associations of multiple genetic loci with plasma levels of factor VII, factor VIII, and von Willebrand factor: The CHARGE (Cohorts for Heart and Aging Research in Genome Epidemiology) Consortium. Circulation 2010; 121: 1382-1392.
    • (2010) Circulation , vol.121 , pp. 1382-1392
    • Smith, N.L.1    Chen, M.H.2    Dehghan, A.3
  • 36
    • 73949130775 scopus 로고    scopus 로고
    • FVII, FVIIa, and downstream markers of extrinsic pathway activation differ by EPCR Ser219Gly variant in healthy men
    • Ireland HA, Cooper JA, Drenos F, et al. FVII, FVIIa, and downstream markers of extrinsic pathway activation differ by EPCR Ser219Gly variant in healthy men. Arterioscler Thromb Vasc Biol 2009; 29: 1968-1974.
    • (2009) Arterioscler Thromb Vasc Biol , vol.29 , pp. 1968-1974
    • Ireland, H.A.1    Cooper, J.A.2    Drenos, F.3
  • 37
    • 65349192772 scopus 로고    scopus 로고
    • Joint effects of common genetic variants on the risk for type 2 diabetes in US men and women of European ancestry
    • Cornelis MC, Qi L, Zhang C, et al. Joint effects of common genetic variants on the risk for type 2 diabetes in US men and women of European ancestry. Ann Intern Med 2009; 150: 541-550.
    • (2009) Ann Intern Med , vol.150 , pp. 541-550
    • Cornelis, M.C.1    Qi, L.2    Zhang, C.3
  • 38
    • 68449086236 scopus 로고    scopus 로고
    • Common polygenic variation contributes to risk of schizophrenia and bipolar disorder
    • International Schizophrenia Consortium
    • International Schizophrenia Consortium, Purcell SM, Wray NR, Stone JL, et al. Common polygenic variation contributes to risk of schizophrenia and bipolar disorder. Nature 2009; 460: 748-752.
    • (2009) Nature , vol.460 , pp. 748-752
    • Purcell, S.M.1    Wray, N.R.2    Stone, J.L.3
  • 39
    • 79959579204 scopus 로고    scopus 로고
    • Genetic risk profiles for depression and anxiety in adult and elderly cohorts
    • Demirkan A, Penninx BW, Hek K, et al. Genetic risk profiles for depression and anxiety in adult and elderly cohorts. Mol Psychiatry 2011; 16: 773-783.
    • (2011) Mol Psychiatry , vol.16 , pp. 773-783
    • Demirkan, A.1    Penninx, B.W.2    Hek, K.3
  • 40
    • 1842539516 scopus 로고    scopus 로고
    • A simple correction for multiple testing for single-nucleotide polymorphisms in linkage disequilibrium with each other
    • Nyholt DR. A simple correction for multiple testing for single-nucleotide polymorphisms in linkage disequilibrium with each other. Am J Hum Genet 2004; 74: 765-769.
    • (2004) Am J Hum Genet , vol.74 , pp. 765-769
    • Nyholt, D.R.1
  • 41
    • 30344462556 scopus 로고    scopus 로고
    • Comparison of type I error for multiple test corrections in large single-nucleotide polymorphism studies using principal components versus haplotype blocking algorithms
    • Nicodemus KK, Liu W, Chase GA, et al. Comparison of type I error for multiple test corrections in large single-nucleotide polymorphism studies using principal components versus haplotype blocking algorithms. BMC Genet 2005; 6 (Suppl 1): S78.
    • (2005) BMC Genet , vol.6 , Issue.SUPPL. 1
    • Nicodemus, K.K.1    Liu, W.2    Chase, G.A.3
  • 42
    • 78049314943 scopus 로고    scopus 로고
    • A multilocus genetic risk score for coronary heart disease: Case-control and prospective cohort analyses
    • Ripatti S, Tikkanen E, Orho-Melander M, et al. A multilocus genetic risk score for coronary heart disease: case-control and prospective cohort analyses. Lancet 2010; 376: 1393-1400.
    • (2010) Lancet , vol.376 , pp. 1393-1400
    • Ripatti, S.1    Tikkanen, E.2    Orho-Melander, M.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.