Altered interactions among thin filament proteins modulate cardiac function

Journal of Molecular and Cellular Cardiology

Volumn 28, Issue 2, 1996, Pages 217-230

  Solaro, R John ^a   Van Eyk, Jennifer ^a  

^a UNIVERSITY OF ILLINOIS   (United States)

Author keywords

Actin; Inotropic agents; Ischemia; Length dependent activation; Phosphorylation; roponin; Tropomyosin

Indexed keywords

INOTROPIC AGENT; MYOSIN; PROTEIN; TROPOMYOSIN; TROPONIN I; TROPONIN T;

FEEDBACK SYSTEM; HEART FUNCTION; HEART MUSCLE; HUMAN; HYPERTROPHIC CARDIOMYOPATHY; MYOFILAMENT; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; PROTEIN PROTEIN INTERACTION; REVIEW; THIN FILAMENT;

EID: 0029920689     PISSN: 00222828     EISSN: None     Source Type: Journal    
DOI: 10.1006/jmcc.1996.0021     Document Type: Review

References (104)

1. AL-HILLAWI E, BHANDAR DG, TRAYER HR, TRAYER IP, 1995. The effects of phosphorylation of cardiac troponin-I on its interactions with actin and cardiac troponin-C. Eur J Biochem 228: 962-970.
2. ALLEN DG, KENTISH JC, 1985. The cellular basis of the length-tension relation in cardiac muscle. J Mol Cell Cardiol 2: 17:821-840.
3. ANDERSON PAW, MALOUF NN, OAKELEY A, PAGANI ED, ALLEN PD, 1991. Troponin T isoform expression in humans: A comparison among normal and failing adult heart, fetal heart, and adult and fetal skeletal muscle. Circ Res 60: 1226-1233.
4. BABU A, SONNENBLICK E, GULATI J, 1988. Molecular basis for the influence of muscle length on myocardial performance. Science 240: 74-76.
5. 2+ on cross-bridge turnover kinetics in skinned single rabbit psoas fibers: implication for regulation of muscle contraction. Proc Natl Acad Sci USA 85: 3265-3269.
6. BUCK SH, STRANG KT, MOSS RL, 1995. Troponin-I isoform expression in immature cardiac myocytes: effect of beta-adrenergic stimulation on calcium sensitivity of tension. Biophys J 68: A71.
7. 2+ in adult rat cardiac myocytes. Circ Res 66: 1143-1155.
8. 2+ homeostasis of cardiac myocytes. Circ Res 69: 540-550.
9. CHALOVICH JM, EISENBERG E, 1982. Inhibition of actomyosin ATPase activity by troponin-tropomyosin without blocking the binding of myosin to actin. J Biol Chem 257: 2432-2437.
10. CHONG PCS, HODGES RS, 1982. Proximity of sulfhydryl groups to the sites of interaction between components of the troponin complex from rabbit skeletal muscle. J Biol Chem 257: 2549-2555.
11. COLE HA, PERRY SV, 1975. The phosphorylation of troponin I from cardiac muscle. Biochem J 149: 525-533.
12. COLYER J, WANG JH, 1991. Dependence of cardiac sarcoplasmic reticulum calcium pump activity on the phosphorylation status of phospholamban. J Biol Chem 266: 17486-17493.
13. DALGARNO DC, GRAND RJA, LEVINE BA, MOIR AJG, SCOTT GMM, PERRY SV, 1982. Interaction between troponin I and troponin C. FEBS Lett 149: 54-58.
14. DONG WJ, XING J, SHE M, CHANDRA M, SOLARO RJ, CHEUNG HC, 1996a. Phosphorylation induced decrease in distance in cardiac troponin I. (Abstract). Biophys J (in press).
15. DONG WJ, XING J, CHANDRA M, SOLARO RJ, CHEUNG HC, 1996b. Fluorescence studies of the N-terminal segment of cardiac troponin I. (Abstract). Biophys J (in press).
16. ENDOH M, SCHUMANN HJ, 1975. Frequency-dependence of the positive inotropic effect of mehoxamine and naphazoline medicated by α-adrenoceptors in isolated rabbit papillary muscle. Naunyn-Schmiedeberg's Arch Pharmacol 287: 377-389.
17. 2+ mediated through α- and β-adrenoceptors. Cire Res 62: 247-265.
18. 2-and COOH-terminal regions of skeletal muscle troponin I. J Biol Chem 269: 5230-5240.
19. FARAH CS, REINACH FC, 1995. The troponin complex and regulation of muscle contraction. FASEB J 9: 755-767.
20. FUCHS F, LIOU Y-M, GRABAREK Z, 1989. The reactivity of sulfhydryl groups of bovine cardiac troponin C. J Biol Chem 264: 20344-20349.
21. GARVEY JE, KRANIAS EG, SOLARO RJ, 1988. Phosphorylation of C-protein, troponin I and phospholamban in isolated rabbit hearts. Biochem J 249: 709-714.
22. GEEVES MA, LEHRER SS, 1994. Dynamics of the muscle thin filament regulatory switch: the size of the cooperative unit. Biophys J 67: 273-282.
23. GREEN L, EISENBERG E, 1980. Cooperative binding of myosin subfragment 1 to the actin-tropomyosin complex. Proc Natl Acad Sci USA 77: 2616-2620.
24. 2-terminal peptide in myofilament activation. J Biol Chem 269: 15210-15216.
25. 2+ sensitivity in intact and skinned muscles from normal and diseased human myocardium. Circ Res 67: 744-652.?
26. HARRISON SM, LAMONE C, MILLER DJ, 1988. Hysteresis and length dependence of calcium sensitivity in chemically skinned rate cardiac muscle. J Physiol (London) 401: 115-143.
27. HIBBERD MG, JEWELL BR, 1982. Calcium- and length-dependent force production in rat ventricular muscle. J Physiol (London) 329: 527-540.
28. HILL TL, EISENBERG E, GREENE LE, 1980. Theoretical model for the cooperative equilibrium binding of myosin subfragment 1 to actin-troponin-tropomyosin. Proc Natl Acad Sci USA 77: 3186-3190.
29. HITCHCOCK-DE GREGORI SE, 1982. Study of the structure of troponin-I by measuring the relative reactivities of lysines with acetic anhydride. J Biol Chem 257: 7372-7380.
30. HOFFMAN PA, FUCHS F, 1988. Bound calcium and force development in skinned cardiac muscle bundles: Effect of sarcomere length. J Mol Cell Cardiol 20: 667-677.
31. HOFFMAN PA, MILLER WP, MOSS RL, 1993. Altered calcium sensitivity of isometric tension in myocyte sized preparations of porcine post-ischemic stunned myocardium. Circ Res 70: 50-56.
32. HOIT BD, KHOURY EG, KRANIAS EG, BALL N, WALSH RA, 1995. In vivo echocardiographic detection of enhanced left ventricular function in gene-targeted mice with phospholamban deficiency. Circ Res 77: 632-637.
33. HOLMES KC, 1995. The actomyosin interaction and its control by tropomyosin. Biophys J 68: 2S-7S.
34. HOLROYDE MJ, HOWE E, SOLARO RJ, 1979. Modification of calcium requirements for activation of cardiac myofibrillar ATPase by cAMP dependent phosphorylation. Biochim Biophys Acta 586: 63-69.
35. HUXLEY HE, 1972. Structural changes in the actin- and myosin-containing filaments during contraction. Cold Spring Harbor Symp Quant Biol 37: 361-376.
36. JOHNSON JA, MOCHLY-ROSEN D, 1995. Inhibition of the spontaneous rate of contraction of neonatal cardiac myocytes by protein kinase C isozymes. A putative role for the ε isozyme. Circ Res 76: 654-663.
37. KARCZEWSKI P, BARTEL S, KRAUSE E-G, 1990. Differential sensitivity to isoprenaline of troponin I and phospholamban phosphorylation in isolated rat hearts. Biochem J 266: 115-122.
38. KLEEREKOPER Q, HOWARTH JW, GUO X, SOLARO RJ, ROSEVEAR PR. Cardiac troponin I induced conformational changes in cardiac troponin C as monitored by NMR using site directed spin and isotope labeling. Biochemistry (in press).
39. KOBAYASHI T, TAO T, GERGELY J, COLLINS JH, 1994. Structure of the troponin complex. J Biol Chem 269: 5725-5729.
40. KRANIAS EG, SOLARO RJ, 1982. Phosphorylation of troponin I and phospholamban during catecholamine stimulation of rabbit heart. Nature 298: 182-184.
41. KRANIAS EG, 1985. Regulation of calcium transport by protein phosphatase activity associated with cardiac sarcoplasmic reticulum. J Biol Chem 260: 11006-11010.
42. KRESS M, HUXLEY HE, FARUQI AR, KOCH MHJ, HENDRIX J, 1984. Thin filament x-ray diffraction in contracting frog muscle. In: The Eighth International Biophysics Congress Abstracts, Bristol, pp 119.
43. KRUDY G, KLEERKOPER Q, GUO X, HOWARTH JW, SOLARO RJ, ROSEVEAR PR, 1994. NMR studies delineating spatial relationships within the cardiac troponin I-troponin C complex. J Biol Chem 269: 23731-23735.
44. 2+-induced tropomyosin movement Limulus thin filaments revealed by three-dimensional reconstruction. Nature 368: 65-67.
45. 2+ or myosin heads? J Mus Res Cell Motility 15: 232-236.
46. LESYZK J, GRABAREK Z, GERGELY J, COLLINS JH, 1990. Characterization of zero-length cross-links between rabbit skeletal muscle troponin C and troponin I: Evidence for direct interaction between the inhibitory region of troponin I and the NH2-terminal, regulatory domain of troponin C. Biochemistry 29: 299-304.
47. LIAO R, WANG CK, CHEUNG HC, 1990. Effect of phosphorylation of cardiac troponin I on the fluorescence properties of its single tryptophan as determined by pico second spectroscopy. SPIE Proceedings 204: 699-705.
48. 2+-ATPase activity in guinea pig ventricles. J Biol Chem 258: 464-471.
49. LUO W, GRUPP IL, HARRER J, PONNIAH S, GRUPP G, DUFFY JJ, DOETSCHMAN T, KRANIAS EG, 1994. Targeted ablation of the phospholamban gene is associated with markedly enhanced myocardial contractility and loss of β-agonist stimulation. Circ Res 75: 401-409.
50. MARTIN AM, BALL K, GAO L, KUMAR PK, SOLARO RJ, 1991. Identification and functional significance of troponin I isoforms in neonatal rat heart myofibrils. Circ Res 69: 1244-1252.
51. 2+ sensitivity of tension in mouse cardiac myocytes expressing skeletal troponin C. J Physiol (London) 483.1: 131-139.
52. 2+ sensitivity of tension at short sarcomere length. Circ Res 77: 199-205.
53. MCKILLOP DF, GEEVES MA, 1993. Regulation of the interaction between actin and myosin subfragment 1 : Evidence for three states of the thin filament. Biophys J 65: 693-701.
54. MILLAR NC, HOMSHER E, 1990. The effect of phosphate and calcium on force generation in glycerinated rabbit skeletal muscle fibers. J Biol Chem 265: 20234-20240.
55. MITTMANN K, JAQUET K, HEILMEYER JR LMG, 1992. Ordered phosphorylation of a duplicated minimal recognition motif for cAMP-dependent protein kinase present in cardiac troponin I. FEBS Lett 302: 133-137.
56. 2+ sensitivity of tension. J Physiol 440: 273-289.
57. MUTHUCHAMY M, GRUPP I, GRUPP G, O'TOOLE B, KIER A, BOLVIN G, NEUMANN J, WIECZOREK D. Molecular and physiological effects of overexpressing striated muscle β-tropomyosin in the adult murine heart. J Biol Chem (in press).
58. NGAI S-M, HODGES RS, 1992. Biologically important interactions between synthetic peptides of the N-terminal region of troponin I and troponin C. J Biol Chem 267: 15715-15720.
59. NGAI S-M, SONNICHSEN FD, HODGES RS, 1994. Photochemical cross-linking between native rabbit skeletal troponin C and benzoyl-troponin I inhibitory peptide residues 104-115. J Biol Chem 269: 2798-2802.
60. 2+-stimulated actomyosin MgATPase activity. J Biol Chem 266: 4974-4978.
61. 2+-dependent actomyosin MgATPase and troponin T binding to tropomyosin F-actin complex. Biochem J 288: 2705-2711.
62. NOLAND JR TA, RAYNOR RL, KUO JF, 1989. Identification of sites phosphorylated in bovine cardiac troponin I and troponin T by protein kinase C and comparative substrate activity of synthetic peptides containing the phosphorylation sites. J Biol Chem 264: 20778-20785.
63. 2+-stimulated MgATPase of reconstituted actomyosin S-1. J Biol Chem 43: 25445-25454.
64. PALMITER KA, KITADA Y, MUTHUCHAMY M, WIECZOREK D, SOLARO RJ, 1995. Use of a transgenic mouse model to investigate the role of tropomyosin isoforms in the regulation of cardiac myofilament activation. Biophys J 68: A55.
65. PALMITER KA, PAN BA, SOLARO RJ, 1994. Effect of sarcomere length and myofilament lattice spacing on the activation properties of triton X-100 skinned soleus muscle fibers. Biophys J 66: A192.
66. 2+ sensitivity at acidic pH. (Abstract). Biophys J (in press).
67. PAN BS, SOLARO RJ, 1987. Calcium-binding properties of troponin C in detergent-skinned heart muscle fibers. J Biol Chem 262: 7839-7849.
68. 2+-specific fluorescence changes upon interaction of troponin I inhibitory peptides with the N and C domains of troponin C tryptophan mutants. Biophys J 68: A166.
69. 2+ regulation of muscle contraction. J Biol Chem 270: 2557-2562.
70. RAYMENT L, HOLDEN H, WHITTAKER M, YOHN CB, LORENZ M, HOLMES KC, MILLIGAN R, 1993. Structure of the actin-myosin complex and its implications for muscle contraction. Science 261: 58-65.
71. 2+-regulatory site of bovine cardiac troponin. J Biol Chem 257: 260-263.
72. RÜEGG JC, SOLARO RJ, 1993. Calcium sensitizing positive inotropic drugs. In: Gwathmey JK, Briggs GM, Allen PD, eds. Heart Failure Basic and Clinical Aspects. Marcel Dekker, Inc., New York, 457-477.
73. 2+ uptake in mammalian ventricular myocytes. Am J Physiol 261: H1344-H1349.
74. SOLARO RJ, 1986. Protein phosphorylation and the cardiac myofilaments. In: Solaro RJ, ed. Protein Phosphorylation in the Heart Muscle. CRC Press Inc, Boca Raton, 129-156.
75. SOLARO RJ, 1993. Modulation of activation of cardiac myofilaments by beta-adrenergic agonists. In: Allen DAG, Lee JA, eds. Modulation of Cardiac Calcium Sensitivity. Oxford, Oxford University Press, 160-177.
76. SOLARO RJ, 1995. Control mechanisms regulating contractile activity of cardiac myofilaments. In: Sperelakis N, ed. Physiology and Pathophysiology of the Heart. Third Edition. Boston, Kluwer Academic Publishers, 355-366.
77. SOLARO RJ, MOIR AJG, PERRY SV, 1976. Phosphorylation of troponin I and the inotropic effect of adrenalin in the perfused rabbit heart. Nature 262: 615-617.
78. 1-Adrenergic receptor stimulation decreases maximum shortening velocity of skinned single ventricular myocytes from rats. Circ Res 77: 114-120.
79. STRAUSS JD, VAN EYK JE, BARTH Z, KLUWE L, MAEDA K, WIESNER RJ, RÜEGG JC, 1995. Recombinant troponin I substitution and calcium responsiveness in skinned cardiac muscle. Pflügers Arch (in press).
80. SWARTZ DR, MOSS RL, 1992. Influence of a strong binding myosin analog on calcium sensitive mechanical properties of skinned skeletal muscle fibers. J Biol Chem 267: 20497-20506.
81. SWIDEREK K, JAQUET K, MEYER HE, HEILMEYER JR LMJ, 1988. Cardiac troponin I, isolated from bovine heart, contains two adjacent phosphoserines. Eur J Biochem 176: 335-342.
82. SYSKA H, WILKINSON JM, GRAND RJA, PERRY SV, 1976. The relationship between biological activity and primary structure of troponin I from white skeletal muscle of the rabbit. Biochem J 153: 375-387.
83. TALBOT JA, HODGES RS, 1981. Synthetic studies on the inhibitory region of rabbit skeletal troponin I. J Biol Chem 256: 2798-2802.
84. TANIGAWA G, JARCHO JA, KASS S, SOLOMON SD, VOSBERG JG, SEIDMAN JG, SEIDMAN CE, 1990. A molecular basis for familial hypertrophic cardiomyopathy: an α/β cardiac myosin heavy chain hybrid gene. Cell 622: 991-998.
85. 1-Adrenergic effects on intracellular pH and calcium and on myofilaments in single rat cardiac cells. J Physiol 447: 275-292.
86. THIERFELDER L, WATKINS H, MACRAE C et al., 1994. Alpha-tropomyosin and cardiac troponin T mutations cause familial hypertrophic cardiomyopathy: a disease of the sarcomere. Cell 77: 701-712.
87. THOMAS LT, VAN EYK JE, FARAH CS, REINACH FC, HODGES RS, SMILLIE LB, 1995. The role of troponin I and troponin T in the calcium-dependent regulation of reconstituted thin filaments. Biophys J 68: A166.
88. TRAUTWEIN W, HESCHELER J, 1990. Regulation of cardiac L-type calcium current by phosphorylation and G proteins. Ann Rev Physiol 52: 257-274.
89. 2+-sensitivity of the acto-S1-TM ATPase activity. (Submitted).
90. VAN EYK JE, HODGES RS, 1988. The biological importance of each amino acid residue of the troponin I inhibitory sequence 104-115 in the interaction with troponin C and tropomyosin-actin. J Biol Chem 263: 1726-1732.
91. VAN EYK JE, HODGES RS, 1993. The use of synthetic peptides to unravel the mechanism of muscle regulation. Methods: A Companion to Methods in Enzymology 5: 264-280.
92. VAN EYK JE, STRAUSS JD, HODGES RS, RÜEGG JC, 1993. A synthetic peptide mimics troponin I function in the calcium-dependent regulation of muscle contraction. FEBS Lett 323: 223-228.
93. VAN EYK JE, TRIPET B, THOMAS L, STRAUSS JD, RÜEGG JC, HODGES RS, 1995. Synthetic peptides unravels muscle regulation. (Abstract). Pflügers Arch (in press).
94. VENEMA RC, KUO JF, 1993. Protein kinase C-mediated phosphorylation of troponin I and C-protein in isolated myocardial cells is associated with inhibition of myofibrillar actomyosin ATPase. J Biol Chem 268: 2705-2711.
95. 2+ on the kinetics of phosphate release in skeletal muscle. J Biol Chem 267: 2459-2456.?
96. 2+-dependent interactions between the C-helix of troponin-C and troponin-T. Photocross-linking and fluorescence studies using a recombinant troponin-C. J Biol Chem 265: 4953-4957.
97. 2+-troponin C affinity in cardiac and slow skeletal muscle. Am J Physiol 266: C1077-C1082.
98. WATTANAPERMPOOL J, GUO X, SOLARO RJ, 1995. The unique amino-terminal peptide of cardiac troponin I regulates myofibrillar ATPase activity only when it is phosphorylated. J Mol Cell Cardiol 27: 1383-1391.
99. WESTFALL MV, SOLARO RJ, 1992. Alterations in myofibrillar function and protein profiles following global ischemia in rat hearts. Circ Res 70: 302-313.
100. WILKINSON JM, GRAND RJA, 1978. Comparison of amino acid sequence of troponin I from different striated muscles. Nature 271: 31-35.
101. WOLSKA BM, LUO W, KRANIAS EG, SOLARO RJ, 1995. Effects of β-adrenergic agonist on contractility of cardiac myocytes isolated from wild-type and phospholamban deficient mice. Biophys J 68: A180.
102. ZHANG R, ZHAO J, POTTER JD, 1994. Cardiac muscle regulation by troponin I phosphorylation. Biophys J 66: A316.
103. ZHANG R, ZHAO J, MANDVENO A, POTTER JD, 1995. Cardiac troponin I phosphorylation increases the rate of cardiac muscle relaxation. Circ Res 76: 1028-1035.
104. ZOT AS, POTTER JD, 1987. Structural aspects of troponin-tropomyosin regulation of skeletal muscle contraction. Ann Rev Biophys Chem 16: 535-559.