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Volumn 135, Issue 15, 2017, Pages 1444-1457

Infarcted Myocardium-Primed Dendritic Cells Improve Remodeling and Cardiac Function after Myocardial Infarction by Modulating the Regulatory T Cell and Macrophage Polarization

Author keywords

dendritic cells; heart failure; macrophage; myocardial infarction; regulatory T cells; ventricular remodeling

Indexed keywords

TUMOR NECROSIS FACTOR; ANTIGEN; BIOLOGICAL MARKER;

EID: 85013374549     PISSN: 00097322     EISSN: 15244539     Source Type: Journal    
DOI: 10.1161/CIRCULATIONAHA.116.023106     Document Type: Article
Times cited : (154)

References (39)
  • 2
    • 77953350982 scopus 로고    scopus 로고
    • Monocytes: Protagonists of infarct inflammation and repair after myocardial infarction
    • Nahrendorf M, Pittet MJ, Swirski FK. Monocytes: protagonists of infarct inflammation and repair after myocardial infarction. Circulation. 2010;121:2437-2445. doi: 10.1161/CIRCULATIONAHA. 109.916346.
    • (2010) Circulation. , vol.121 , pp. 2437-2445
    • Nahrendorf, M.1    Pittet, M.J.2    Swirski, F.K.3
  • 3
    • 84899010755 scopus 로고    scopus 로고
    • Anti-inflammatory strategies for ventricular remodeling following ST-segment elevation acute myocardial infarction
    • Seropian IM, Toldo S, Van Tassell BW, Abbate A. Anti-inflammatory strategies for ventricular remodeling following ST-segment elevation acute myocardial infarction. J Am Coll Cardiol. 2014;63:1593-1603. doi: 10.1016/j.jacc.2014.01.014.
    • (2014) J Am Coll Cardiol. , vol.63 , pp. 1593-1603
    • Seropian, I.M.1    Toldo, S.2    Van Tassell, B.W.3    Abbate, A.4
  • 5
    • 84903216099 scopus 로고    scopus 로고
    • Foxp3+ CD4+ T cells improve healing after myocardial infarction by modulating monocyte/macrophage differentiation
    • Weirather J, Hofmann UD, Beyersdorf N, Ramos GC, Vogel B, Frey A, Ertl G, Kerkau T, Frantz S. Foxp3+ CD4+ T cells improve healing after myocardial infarction by modulating monocyte/macrophage differentiation. Circ Res. 2014;115:55-67. doi: 10.1161/ CIRCRESAHA.115.303895.
    • (2014) Circ Res. , vol.115 , pp. 55-67
    • Weirather, J.1    Hofmann, U.D.2    Beyersdorf, N.3    Ramos, G.C.4    Vogel, B.5    Frey, A.6    Ertl, G.7    Kerkau, T.8    Frantz, S.9
  • 7
    • 84908089142 scopus 로고    scopus 로고
    • TREG-cell therapies for autoimmune rheumatic diseases
    • Miyara M, Ito Y, Sakaguchi S. TREG-cell therapies for autoimmune rheumatic diseases. Nat Rev Rheumatol. 2014;10:543-551. doi: 10.1038/nrrheum.2014.105.
    • (2014) Nat Rev Rheumatol. , vol.10 , pp. 543-551
    • Miyara, M.1    Ito, Y.2    Sakaguchi, S.3
  • 8
    • 70249122695 scopus 로고    scopus 로고
    • First-in-man clinical results of the treatment of patients with graft versus host disease with human ex vivo expanded CD4+CD25+CD127-T regulatory cells
    • Trzonkowski P, Bieniaszewska M, Juścińska J, Dobyszuk A, Krzystyniak A, Marek N, Myśliwska J, Hellmann A. First-in-man clinical results of the treatment of patients with graft versus host disease with human ex vivo expanded CD4+CD25+CD127-T regulatory cells. Clin Immunol. 2009;133:22-26. doi: 10.1016/j. clim.2009.06.001.
    • (2009) Clin Immunol. , vol.133 , pp. 22-26
    • Trzonkowski, P.1    Bieniaszewska, M.2    Juścińska, J.3    Dobyszuk, A.4    Krzystyniak, A.5    Marek, N.6    Myśliwska, J.7    Hellmann, A.8
  • 10
    • 84864036920 scopus 로고    scopus 로고
    • Photodynamic therapy-mediated DC immunotherapy is highly effective for the inhibition of established solid tumors
    • Jung NC, Kim HJ, Kang MS, Lee JH, Song JY, Seo HG, Bae YS, Lim DS. Photodynamic therapy-mediated DC immunotherapy is highly effective for the inhibition of established solid tumors. Cancer Lett. 2012;324:58-65. doi: 10.1016/j. canlet.2012.04.024.
    • (2012) Cancer Lett. , vol.324 , pp. 58-65
    • Jung, N.C.1    Kim, H.J.2    Kang, M.S.3    Lee, J.H.4    Song, J.Y.5    Seo, H.G.6    Bae, Y.S.7    Lim, D.S.8
  • 12
    • 0033939942 scopus 로고    scopus 로고
    • Immature dendritic cells generated with low doses of GM-CSF in the absence of IL-4 are maturation resistant and prolong allograft survival in vivo
    • Lutz MB, Suri RM, Niimi M, Ogilvie AL, Kukutsch NA, Rössner S, Schuler G, Austyn JM. Immature dendritic cells generated with low doses of GM-CSF in the absence of IL-4 are maturation resistant and prolong allograft survival in vivo. Eur J Immunol. 2000;30:1813-1822. doi: 10.1002/1521-4141(200007)30 CO;2-8.
    • (2000) Eur J Immunol. , vol.30 , pp. 1813-1822
    • Lutz, M.B.1    Suri, R.M.2    Niimi, M.3    Ogilvie, A.L.4    Kukutsch, N.A.5    Rössner, S.6    Schuler, G.7    Austyn, J.M.8
  • 13
    • 78649852489 scopus 로고    scopus 로고
    • Therapeutic effect of tolerogenic dendritic cells in established collagen-induced arthritis is associated with a reduction in Th17 responses
    • Stoop JN, Harry RA, von Delwig A, Isaacs JD, Robinson JH, Hilkens CM. Therapeutic effect of tolerogenic dendritic cells in established collagen-induced arthritis is associated with a reduction in Th17 responses. Arthritis Rheum. 2010;62:3656-3665. doi: 10.1002/art.27756.
    • (2010) Arthritis Rheum. , vol.62 , pp. 3656-3665
    • Stoop, J.N.1    Harry, R.A.2    Von Delwig, A.3    Isaacs, J.D.4    Robinson, J.H.5    Hilkens, C.M.6
  • 14
    • 0034653828 scopus 로고    scopus 로고
    • CD8+ T cell-dependent elimination of dendritic cells in vivo limits the induction of antitumor immunity
    • Hermans IF, Ritchie DS, Yang J, Roberts JM, Ronchese F. CD8+ T cell-dependent elimination of dendritic cells in vivo limits the induction of antitumor immunity. J Immunol. 2000;164:3095-3101.
    • (2000) J Immunol. , vol.164 , pp. 3095-3101
    • Hermans, I.F.1    Ritchie, D.S.2    Yang, J.3    Roberts, J.M.4    Ronchese, F.5
  • 15
    • 85027952623 scopus 로고    scopus 로고
    • Noninvasive assessment of myocardial inflammation by cardiovascular magnetic resonance in a rat model of experimental autoimmune myocarditis
    • Moon H, Park HE, Kang J, Lee H, Cheong C, Lim YT, Ihm SH, Seung KB, Jaffer FA, Narula J, Chang K, Hong KS. Noninvasive assessment of myocardial inflammation by cardiovascular magnetic resonance in a rat model of experimental autoimmune myocarditis. Circulation. 2012;125:2603-2612. doi: 10.1161/CIRCULATIONAHA. 111.075283.
    • (2012) Circulation. , vol.125 , pp. 2603-2612
    • Moon, H.1    Park, H.E.2    Kang, J.3    Lee, H.4    Cheong, C.5    Lim, Y.T.6    Ihm, S.H.7    Seung, K.B.8    Jaffer, F.A.9    Narula, J.10    Chang, K.11    Hong, K.S.12
  • 16
    • 67649910765 scopus 로고    scopus 로고
    • Semi-mature DC are immunogenic and not tolerogenic when inoculated at a high dose in collagen-induced arthritis mice
    • Lim DS, Kang MS, Jeong JA, Bae YS. Semi-mature DC are immunogenic and not tolerogenic when inoculated at a high dose in collagen-induced arthritis mice. Eur J Immunol. 2009;39:1334-1343. doi: 10.1002/eji.200838987.
    • (2009) Eur J Immunol. , vol.39 , pp. 1334-1343
    • Lim, D.S.1    Kang, M.S.2    Jeong, J.A.3    Bae, Y.S.4
  • 17
    • 84880748603 scopus 로고    scopus 로고
    • Pathological ventricular remodeling: Mechanisms: Part 1 of 2
    • Burchfield JS, Xie M, Hill JA. Pathological ventricular remodeling: mechanisms: part 1 of 2. Circulation. 2013;128:388-400. doi: 10.1161/CIRCULATIONAHA.113.001878.
    • (2013) Circulation. , vol.128 , pp. 388-400
    • Burchfield, J.S.1    Xie, M.2    Hill, J.A.3
  • 18
    • 78650985392 scopus 로고    scopus 로고
    • Left ventricular remodeling in the postinfarction heart: A review of cellular, molecular mechanisms, and therapeutic modalities
    • Gajarsa JJ, Kloner RA. Left ventricular remodeling in the postinfarction heart: a review of cellular, molecular mechanisms, and therapeutic modalities. Heart Fail Rev. 2011;16:13-21. doi: 10.1007/s10741-010-9181-7.
    • (2011) Heart Fail Rev. , vol.16 , pp. 13-21
    • Gajarsa, J.J.1    Kloner, R.A.2
  • 20
    • 0025266820 scopus 로고
    • Ventricular remodeling after myocardial infarction: Experimental observations and clinical implications
    • Pfeffer MA, Braunwald E. Ventricular remodeling after myocardial infarction: experimental observations and clinical implications. Circulation. 1990;81:1161-1172.
    • (1990) Circulation. , vol.81 , pp. 1161-1172
    • Pfeffer, M.A.1    Braunwald, E.2
  • 22
    • 77955713353 scopus 로고    scopus 로고
    • STEMI and heart failure in the elderly: Role of adverse remodeling
    • Jelani A, Jugdutt BI. STEMI and heart failure in the elderly: role of adverse remodeling. Heart Fail Rev. 2010;15:513-521. doi: 10.1007/s10741-010-9177-3.
    • (2010) Heart Fail Rev. , vol.15 , pp. 513-521
    • Jelani, A.1    Jugdutt, B.I.2
  • 23
    • 33750846654 scopus 로고    scopus 로고
    • Large-scale expansion of rat CD4+ CD25+ T(reg) cells in the absence of T-cell receptor stimulation
    • Beyersdorf N, Balbach K, Hünig T, Kerkau T. Large-scale expansion of rat CD4+ CD25+ T(reg) cells in the absence of T-cell receptor stimulation. Immunology. 2006;119:441-450. doi: 10.1111/j.1365-2567.2006.02455.x.
    • (2006) Immunology. , vol.119 , pp. 441-450
    • Beyersdorf, N.1    Balbach, K.2    Hünig, T.3    Kerkau, T.4
  • 25
    • 0345827684 scopus 로고    scopus 로고
    • Dendritic cells: Emerging pharmacological targets of immunosuppressive drugs
    • Hackstein H, Thomson AW. Dendritic cells: emerging pharmacological targets of immunosuppressive drugs. Nat Rev Immunol. 2004;4:24-34. doi: 10.1038/nri1256.
    • (2004) Nat Rev Immunol. , vol.4 , pp. 24-34
    • Hackstein, H.1    Thomson, A.W.2
  • 26
    • 0344984407 scopus 로고    scopus 로고
    • Dendritic cells: Regulators of alloimmunity and opportunities for tolerance induction
    • Morelli AE, Thomson AW. Dendritic cells: regulators of alloimmunity and opportunities for tolerance induction. Immunol Rev. 2003;196:125-146.
    • (2003) Immunol Rev. , vol.196 , pp. 125-146
    • Morelli, A.E.1    Thomson, A.W.2
  • 27
    • 34547152610 scopus 로고    scopus 로고
    • Tolerogenic dendritic cells and the quest for transplant tolerance
    • Morelli AE, Thomson AW. Tolerogenic dendritic cells and the quest for transplant tolerance. Nat Rev Immunol. 2007;7:610-621. doi: 10.1038/nri2132.
    • (2007) Nat Rev Immunol. , vol.7 , pp. 610-621
    • Morelli, A.E.1    Thomson, A.W.2
  • 28
    • 0037033427 scopus 로고    scopus 로고
    • Repetitive injections of dendritic cells matured with tumor necrosis factor alpha induce antigen-specific protection of mice from autoimmunity
    • Menges M, Rössner S, Voigtländer C, Schindler H, Kukutsch NA, Bogdan C, Erb K, Schuler G, Lutz MB. Repetitive injections of dendritic cells matured with tumor necrosis factor alpha induce antigen-specific protection of mice from autoimmunity. J Exp Med. 2002;195:15-21.
    • (2002) J Exp Med. , vol.195 , pp. 15-21
    • Menges, M.1    Rössner, S.2    Voigtländer, C.3    Schindler, H.4    Kukutsch, N.A.5    Bogdan, C.6    Erb, K.7    Schuler, G.8    Lutz, M.B.9
  • 29
    • 79961235625 scopus 로고    scopus 로고
    • Developing tolerogenic dendritic cell therapy for rheumatoid arthritis: What can we learn from mouse models
    • Stoop JN, Robinson JH, Hilkens CM. Developing tolerogenic dendritic cell therapy for rheumatoid arthritis: what can we learn from mouse models? Ann Rheum Dis. 2011;70:1526-1533. doi: 10.1136/ard.2011.151654.
    • (2011) Ann Rheum Dis. , vol.70 , pp. 1526-1533
    • Stoop, J.N.1    Robinson, J.H.2    Hilkens, C.M.3
  • 30
    • 84856094049 scopus 로고    scopus 로고
    • Phase i (safety) study of autologous tolerogenic dendritic cells in type 1 diabetic patients
    • Giannoukakis N, Phillips B, Finegold D, Harnaha J, Trucco M. Phase I (safety) study of autologous tolerogenic dendritic cells in type 1 diabetic patients. Diabetes Care. 2011;34:2026-2032. doi: 10.2337/dc11-0472.
    • (2011) Diabetes Care. , vol.34 , pp. 2026-2032
    • Giannoukakis, N.1    Phillips, B.2    Finegold, D.3    Harnaha, J.4    Trucco, M.5
  • 31
    • 78149277909 scopus 로고    scopus 로고
    • How tolerogenic dendritic cells induce regulatory T cells
    • Maldonado RA, von Andrian UH. How tolerogenic dendritic cells induce regulatory T cells. Adv Immunol. 2010;108:111-165. doi: 10.1016/B978-0-12-380995-7.00004-5.
    • (2010) Adv Immunol. , vol.108 , pp. 111-165
    • Maldonado, R.A.1    Von Andrian, U.H.2
  • 32
    • 84899650478 scopus 로고    scopus 로고
    • The inflammatory response in myocardial injury, repair, and remodelling
    • Frangogiannis NG. The inflammatory response in myocardial injury, repair, and remodelling. Nat Rev Cardiol. 2014;11:255-265. doi: 10.1038/nrcardio.2014.28.
    • (2014) Nat Rev Cardiol. , vol.11 , pp. 255-265
    • Frangogiannis, N.G.1
  • 33
    • 84872166189 scopus 로고    scopus 로고
    • Leukocyte behavior in atherosclerosis, myocardial infarction, and heart failure
    • Swirski FK, Nahrendorf M. Leukocyte behavior in atherosclerosis, myocardial infarction, and heart failure. Science. 2013;339:161-166. doi: 10.1126/science.1230719.
    • (2013) Science. , vol.339 , pp. 161-166
    • Swirski, F.K.1    Nahrendorf, M.2
  • 36
    • 84902994989 scopus 로고    scopus 로고
    • Regulating repair: Regulatory T cells in myocardial infarction
    • Nahrendorf M, Swirski FK. Regulating repair: regulatory T cells in myocardial infarction. Circ Res. 2014;115:7-9. doi: 10.1161/ CIRCRESAHA.114.304295.
    • (2014) Circ Res. , vol.115 , pp. 7-9
    • Nahrendorf, M.1    Swirski, F.K.2
  • 37
    • 67649864074 scopus 로고    scopus 로고
    • Nasal vaccination with troponin reduces troponin specific T-cell responses and improves heart function in myocardial ischemia-reperfusion injury
    • Frenkel D, Pachori AS, Zhang L, Dembinsky-Vaknin A, Farfara D, Petrovic-Stojkovic S, Dzau VJ, Weiner HL. Nasal vaccination with troponin reduces troponin specific T-cell responses and improves heart function in myocardial ischemia-reperfusion injury. Int Immunol. 2009;21:817-829. doi: 10.1093/intimm/ dxp051.
    • (2009) Immunol. , vol.21 , pp. 817-829
    • Frenkel, D.1    Pachori, A.S.2    Zhang, L.3    Dembinsky-Vaknin, A.4    Farfara, D.5    Petrovic-Stojkovic, S.6    Dzau, V.J.7    Weiner, H.L.8
  • 38
    • 33644863719 scopus 로고    scopus 로고
    • Factor XIII (FXIII) and angiogenesis
    • Dardik R, Loscalzo J, Inbal A. Factor XIII (FXIII) and angiogenesis. J Thromb Haemost. 2006;4:19-25. doi: 10.1111/j.1538-7836.2005.01473.x.
    • (2006) J Thromb Haemost. , vol.4 , pp. 19-25
    • Dardik, R.1    Loscalzo, J.2    Inbal, A.3
  • 39
    • 33947523753 scopus 로고    scopus 로고
    • Endothelial progenitor cells: Characterization, in vitro expansion, and prospects for autologous cell therapy
    • Smadja DM, Cornet A, Emmerich J, Aiach M, Gaussem P. Endothelial progenitor cells: characterization, in vitro expansion, and prospects for autologous cell therapy. Cell Biol Toxicol. 2007;23:223-239. doi: 10.1007/s10565-007-0177-6.
    • (2007) Cell Biol Toxicol. , vol.23 , pp. 223-239
    • Smadja, D.M.1    Cornet, A.2    Emmerich, J.3    Aiach, M.4    Gaussem, P.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.