DNA damage is a pervasive cause of sequencing errors, directly confounding variant identification

Science

Volumn 355, Issue 6326, 2017, Pages 752-756

  Chen, Lixin ^a   Liu, Pingfang ^a   Evans, Thomas C ^a   Ettwiller, Laurence M ^a  

^a NEW ENGLAND BIOLABS   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

GENOMIC DNA;

CANCER; DAMAGE; DNA; ERROR ANALYSIS; GENETIC ANALYSIS; GENOMICS; IDENTIFICATION METHOD; MUTATION; PATHOLOGY; PHENOTYPE;

ARTICLE; DNA DAMAGE; DNA REPAIR; DNA SEQUENCE; GENE FREQUENCY; GENE MUTATION; GENETIC ALGORITHM; GENETIC DATABASE; GENETIC VARIABILITY; GENETIC VARIATION; GERMLINE MUTATION; HUMAN; MALIGNANT NEOPLASM; PRIORITY JOURNAL; SOMATIC MUTATION; ARTIFACT; DNA MUTATIONAL ANALYSIS; GENETICS; HUMAN GENOME PROJECT; MUTATION; NEOPLASM; STANDARDS; STATISTICS AND NUMERICAL DATA;

ARTIFACTS; DNA DAMAGE; DNA MUTATIONAL ANALYSIS; GENETIC VARIATION; HUMAN GENOME PROJECT; HUMANS; MUTATION; NEOPLASMS;

EID: 85013170830     PISSN: 00368075     EISSN: 10959203     Source Type: Journal    
DOI: 10.1126/science.aai8690     Document Type: Article

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