Monoclonal antibody against Toll-like receptor 4 attenuatesventilator-induced lung injury in rats by inhibitingMyD88-and NF-κB-dependent signaling

International Journal of Molecular Medicine

Volumn 39, Issue 3, 2017, Pages 693-700

  Huang, Cuiyuan ^a   Pan, Linghui ^a   Lin, Fei ^a   Dai, Huijun ^a   Fu, Ruili ^a  

^a GUANGXI MEDICAL UNIVERSITY   (China)

Author keywords

Myeloid differentiation factor 88; Nuclear factor B; Signaling; Toll like receptor 4; Ventilator induced lung injury

Indexed keywords

IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 1BETA; INTERLEUKIN 6; MESSENGER RNA; MONOCLONAL ANTIBODY; MYELOID DIFFERENTIATION FACTOR 88; TOLL LIKE RECEPTOR 4; TOLL LIKE RECEPTOR 4 ANTIBODY; TOLL LIKE RECEPTOR 9; TUMOR NECROSIS FACTOR; UNCLASSIFIED DRUG; CYTOKINE;

ADULT; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; ARTIFICIAL VENTILATION; BRONCHOALVEOLAR LAVAGE FLUID; CELL INFILTRATION; CONTROLLED STUDY; DISEASE SEVERITY; GENE EXPRESSION; HISTOPATHOLOGY; IN VITRO STUDY; IN VIVO STUDY; INFLAMMATION; LUNG ALVEOLUS MACROPHAGE; LUNG EDEMA; MALE; MECHANICAL VENTILATOR; MEMBRANE PERMEABILITY; NONHUMAN; PNEUMONIA; PROTEIN BLOOD LEVEL; PROTEIN EXPRESSION; PROTEIN FUNCTION; RAT; SIGNAL TRANSDUCTION; TIDAL VOLUME; TLR4 GENE; TLR9 GENE; TRACHEOTOMY; VENTILATOR INDUCED LUNG INJURY; ANIMAL; ANTAGONISTS AND INHIBITORS; DISEASE MODEL; DRUG EFFECTS; GENETICS; METABOLISM; PATHOLOGY; PULMONARY EDEMA; ULTRASTRUCTURE; VENTILATOR-INDUCED LUNG INJURY;

ANIMALS; ANTIBODIES, MONOCLONAL; BRONCHOALVEOLAR LAVAGE FLUID; CYTOKINES; DISEASE MODELS, ANIMAL; MACROPHAGES, ALVEOLAR; MALE; MYELOID DIFFERENTIATION FACTOR 88; NF-KAPPA B; PULMONARY EDEMA; RATS; RNA, MESSENGER; SIGNAL TRANSDUCTION; TOLL-LIKE RECEPTOR 4; TUMOR NECROSIS FACTOR-ALPHA; VENTILATOR-INDUCED LUNG INJURY;

EID: 85013040553     PISSN: 11073756     EISSN: 1791244X     Source Type: Journal    
DOI: 10.3892/ijmm.2017.2873     Document Type: Article

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